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World Journal of Men's Health

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https://read.qxmd.com/read/30644235/traditional-chinese-medicine-as-a-remedy-for-male-infertility-a-review
#1
REVIEW
Shao Hu Zhou, Yu Fei Deng, Zhi Wei Weng, Hao Wei Weng, Zhi Dan Liu
Male infertility (MI) is a complex multifactorial disease, and idiopathic infertility accounts for 30% of cases of MI. At present, the evidence for the effectiveness of empirical drugs is limited, and in vitro fertilization is costly and may increase the risk of birth defects and childhood cancers. Therefore, affected individuals may feel obliged to pursue natural remedies. Traditional Chinese medicine (TCM) may represent a useful option for infertile men. It has been demonstrated that TCM can regulate the hypothalamic-pituitary-testicular axis and boost the function of Sertoli cells and Leydig cells...
January 10, 2019: World Journal of Men's Health
https://read.qxmd.com/read/30644234/the-relationships-between-thyroid-hormone-levels-and-lower-urinary-tract-symptoms-benign-prostatic-hyperplasia
#2
Jun Ho Lee, Yeon Won Park, Sung Won Lee
PURPOSE: We examined the association between thyroid hormone and lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: A total of 5,708 middle aged men were included. LUTS/BPH were assessed using the international prostate symptom score (IPSS), total prostate volume (TPV), maximal flow rate (Qmax), and a full metabolic workup. Thyroid stimulating hormone (TSH) and free thyroxine (FT4) levels were measured using chemiluminescence immunoassay...
January 4, 2019: World Journal of Men's Health
https://read.qxmd.com/read/30644236/review-of-guidelines-for-the-evaluation-and-treatment-of-leukocytospermia-in-male-infertility
#3
REVIEW
Robert J Brunner, Jonathan H Demeter, Puneet Sindhwani
Leukocytospermia is an ill-defined and poorly understood condition affecting up to 30% of male factor infertility. Current guidelines on leukocytospermia vary significantly, although it has been linked to increased rates of infertility, uncertainty about its clinical significance, diagnosis, and treatment remains. The guidelines are conflicting with sparse data scattered across different specialties and continents. This study aims to compare and contrast available international guidelines and recommendations...
December 31, 2018: World Journal of Men's Health
https://read.qxmd.com/read/30588787/persistent-erectile-dysfunction-after-discontinuation-of-5-alpha-reductase-inhibitor-therapy-in-rats-depending-on-the-duration-of-treatment
#4
Hyun Hwan Sung, Jiwoong Yu, Su Jeong Kang, Mee Ree Chae, Insuk So, Jong Kwan Park, Sung Won Lee
PURPOSE: The current study is aimed to assess whether a longer duration of 5α-reductase inhibitor (5α-RI) exposure was associated with higher rate of permanent erectile dysfunction (ED) in a rat model. MATERIALS AND METHODS: Male Sprague-Dawley rats (n=76) were assigned to five groups: (i) normal control group; (ii) dutasteride (0.5 mg/rat/d) for 4-weeks group; (iii) dutasteride for 4-weeks plus 2-weeks of resting group; (iv) dutasteride for 8-weeks group; and (v) dutasteride for 8-weeks plus 2-weeks of resting group...
December 26, 2018: World Journal of Men's Health
https://read.qxmd.com/read/30588786/long-term-experience-of-sperm-cryopreservation-in-cancer-patients-in-a-single-fertility-center
#5
Seung Hun Song, Dae Keun Kim, Su Ye Sung, Young Sun Her, Ok Hee Lee, Myoung Hwa Choi, Hae Kyung Kim, Sang Woo Lyu, Dong Suk Kim
PURPOSE: Sperm cryopreservation before cancer treatment is the most effective method to preserve the fertility of male patients. We present our 21 years experience with sperm cryopreservation for cancer patients, including an examination of semen quality, the current status of cryopreserved sperm, and the rate of sperm use for assisted reproductive technology (ART). MATERIALS AND METHODS: A total of 721 cancer patients at Fertility Center of CHA Gangnam Medical Center successfully performed sperm cryopreservation for fertility preservation from January 1996 to December 2016...
December 26, 2018: World Journal of Men's Health
https://read.qxmd.com/read/30588785/it-s-time-to-take-advantage-of-robotic-assisted-simple-prostatectomy-in-large-benign-prostatic-hyperplasia
#6
LETTER
Myong Kim, Yu Seob Shin
No abstract text is available yet for this article.
December 21, 2018: World Journal of Men's Health
https://read.qxmd.com/read/30588784/new-insights-on-the-mechanisms-affecting-fertility-in-men-with-non-seminoma-testicular-cancer-before-cancer-therapy
#7
Tania R Dias, Ashok Agarwal, Peter N Pushparaj, Gulfam Ahmad, Rakesh Sharma
PURPOSE: Patients with non-seminoma testicular cancer (NSTC) cancer can be subfertile or infertile, and present reduced sperm quality, but the underlying mechanisms are unknown. The aim of this study was to compare the sperm proteome of patients with NSTC, who cryopreserved their sperm before starting cancer treatment, with that from healthy fertile men. MATERIALS AND METHODS: Semen volume, sperm motility and sperm concentration were evaluated before the cryopreservation of samples from patients with NSTC (n=15) and the control group (n=15)...
December 21, 2018: World Journal of Men's Health
https://read.qxmd.com/read/30588783/metabolic-syndrome-is-an-independent-risk-factor-for-acquired-premature-ejaculation
#8
Seong Uk Jeh, Sol Yoon, Jae Hwi Choi, Jungmo Do, Deok Ha Seo, Sin Woo Lee, See Min Choi, Chunwoo Lee, Sung Chul Kam, Jeong Seok Hwa, Ky Hyun Chung, Ho Won Kang, Jae Seog Hyun
PURPOSE: To determine the role of metabolic syndrome (MetS) as a risk factor for acquired premature ejaculation (PE) after considering the various risk factors, such as lower urinary tract symptoms, erectile dysfunction, hypogonadism, and prostatitis. MATERIALS AND METHODS: From January 2012 to January 2017, records of 1,029 men were analyzed. We performed multivariate analysis to identify risk factors for PE, including the covariate of age, marital status, International Prostate Symptom Score, International Index of Erectile Function (IIEF) score, National Institutes of Health-Chronic Prostatitis Symptom Index (NIH-CPSI) score, serum testosterone levels, and all components of MetS...
December 11, 2018: World Journal of Men's Health
https://read.qxmd.com/read/30588782/changes-in-the-prevalence-and-risk-factors-of-erectile-dysfunction-during-a-decade-the-korean-internet-sexuality-survey-kiss-a-10-year-interval-web-based-survey
#9
Won Hoon Song, Juhyun Park, Sangjun Yoo, Sohee Oh, Sung Yong Cho, Min Chul Cho, Hyeon Jeong, Hwancheol Son
PURPOSE: Although the prevalence of erectile dysfunction (ED) can be affected by social changes, this association has not been well evaluated. We aimed to evaluate the prevalence and risk factors of ED through a 10-year-interval web-based survey using the previous database of same group of panels, with same methodology. MATERIALS AND METHODS: We sent e-mails and surveyed the panels registered in the Internet survey agency. RESULTS: In total, 900 participants were recruited in 2016...
December 5, 2018: World Journal of Men's Health
https://read.qxmd.com/read/30588781/the-impact-of-clostridium-histolyticum-collagenase-on-the-prevalence-and-management-of-peyronie-s-disease-in-the-united-states
#10
Andrew J Sun, Shufeng Li, Michael L Eisenberg
PURPOSE: We evaluated the impact of collagenase clostridium histolyticum (CCH) on rates of diagnosis, treatment, and corporal rupture in Peyronie's disease (PD). We examined the impact of CCH on cost of PD treatment. MATERIALS AND METHODS: We extracted data on PD diagnosis (ICD-9 607.95 and ICD-10 N48.6), corporal rupture (ICD-9 959.13 and ICD-10 S39.840A), CCH use (J0775), penile injections (CPT 54200), and corporal rupture repair from 2008 to 2016 in men over 40 years old using the Clinformatics® Data Mart Database (3...
November 30, 2018: World Journal of Men's Health
https://read.qxmd.com/read/30588780/comparison-of-improving-effects-for-diabetic-erectile-dysfunction-according-to-the-anti-glycemic-agents-phlorizin-and-insulin
#11
Juhyun Park, Ohseong Kwon, Sung Yong Cho, Min Chul Cho, Jae Seung Paick, Soo Woong Kim
PURPOSE: To compare the improving effects of diabetic erectile dysfunction with two anti-glycemic agents; phlorizin and insulin. MATERIALS AND METHODS: Sixty Sprague-Dawley rats were divided into four groups (n=15 in each group): normal control (C), untreated diabetic rats (D), and diabetic rats treated by phlorizin (P) or insulin (I). Ten weeks after the diabetic induction using an injection of streptozotocin (55 mg/kg), four weeks of diabetic control was conducted...
November 27, 2018: World Journal of Men's Health
https://read.qxmd.com/read/30588779/recovery-of-spermatogenesis-following-cancer-treatment-with-cytotoxic-chemotherapy-and-radiotherapy
#12
REVIEW
Keisuke Okada, Masato Fujisawa
The survival rates of boys and men with cancer have increased due to advances in cancer treatments; however, maintenance of quality of life, including fertility preservation, remains a major issue. Fertile male patients who receive radiation and/or chemotherapy face temporary, long-term, or permanent gonadal damage, particularly with exposure to alkylating agents and whole-body irradiation, which sometimes induce critical germ cell damage. These cytotoxic treatments have a significant impact on a patient's ability to have their own biological offspring, which is of particular concern to cancer patients of reproductive age...
November 27, 2018: World Journal of Men's Health
https://read.qxmd.com/read/30588778/epigenetics-of-male-fertility-effects-on-assisted-reproductive-techniques
#13
REVIEW
Filippo Giacone, Rossella Cannarella, Laura M Mongioì, Angela Alamo, Rosita A Condorelli, Aldo E Calogero, Sandro La Vignera
During the last decades the study of male infertility and the introduction of the assisted reproductive techniques (ARTs) has allowed to understand that normal sperm parameters do not always predict fertilization. Sperm genetic components could play an important role in the early stages of embryonic development. Based on these acquisitions, several epigenetic investigations have been developed on spermatozoa, with the aim of understanding the multifactorial etiology of male infertility and of showing whether embryonic development may be influenced by sperm epigenetic abnormalities...
November 27, 2018: World Journal of Men's Health
https://read.qxmd.com/read/30584994/effect-of-korean-herbal-formula-modified-ojayeonjonghwan-on-androgen-receptor-expression-in-an-aging-rat-model-of-late-onset-hypogonadism
#14
Sae Woong Choi, Seung Hwan Jeon, Eun Bi Kwon, Guan Qun Zhu, Kyu Won Lee, Jin Bong Choi, Hyun Cheol Jeong, Kang Sup Kim, Sang Rak Bae, Woong Jin Bae, Su Jin Kim, Hyuk Jin Cho, U Syn Ha, Sung Hoo Hong, Sung Yeoun Hwang, Sae Woong Kim
PURPOSE: Testosterone replacement therapy is an effective treatment for late-onset hypogonadism (LOH) despite a few contraindications and side-effects. The aim of this study was to determine whether modified Ojayeonjonghwan (KH-204, Korean herbal formula) improved LOH. KH-204 is a strong antioxidant herbal formula. We evaluated the effect of Korean herbal prescription on androgen receptor (AR) expression in an aged rat model of LOH. MATERIALS AND METHODS: Eighteen-month-old rats were used as aged LOH rat models...
January 2019: World Journal of Men's Health
https://read.qxmd.com/read/30584993/neutrophil-lymphocyte-ratio-predicts-organ-salvage-in-testicular-torsion-with-marginal-diagnostic-delay
#15
Jun Bo Jang, Young Hwii Ko, Jae Young Choi, Phil Hyun Song, Ki Hak Moon, Hee Chang Jung
PURPOSE: Though prompt diagnosis to minimize symptom duration (SD) is highly associated with organ salvage in cases of testicular torsion (TT), SD is subjective and hard to determine. We thus investigated the clinical implications of systemic inflammatory responses (SIRs) as potential surrogates of SD to improve testis survival. MATERIALS AND METHODS: Sixty men with TT that underwent immediate operation among orchiectomy and orchiopexy following a visit to a single emergency department were retrospectively enrolled...
January 2019: World Journal of Men's Health
https://read.qxmd.com/read/30584992/choroidal-thickness-analysis-in-patients-with-erectile-dysfunction
#16
Yong Kyu Kim, Jang Hoon Lee, Sung Pyo Park, Dae Yul Yang
PURPOSE: To investigate the morphological features of choroidal vasculature in patients with erectile dysfunction (ED) by analyzing choroidal thickness using optical coherence tomography. MATERIALS AND METHODS: We enrolled 39 patients with ED and 19 controls. ED was defined as an erectile function domain score <26 on the International Index of Erectile Function (IIEF) questionnaire. Small-choroidal-vessel-layer (SCVL) thickness was calculated by subtracting large-choroidal-vessel-layer (which corresponded to Haller's layer) thickness from total choroidal thickness...
January 2019: World Journal of Men's Health
https://read.qxmd.com/read/30584991/testicular-fine-needle-aspiration-for-sperm-retrieval-in-azoospermia-a-small-step-toward-the-technical-standardization
#17
Gianmartin Cito, Maria Elisabetta Coccia, Francesco Sessa, Andrea Cocci, Pierangelo Verrienti, Rita Picone, Rossella Fucci, Luciana Criscuoli, Sergio Serni, Marco Carini, Alessandro Natali
PURPOSE: The aim was to describe our preliminary experience performing testicular fine-needle aspiration (TEFNA) with a larger needle in infertile patients with obstructive azoospermia, and to provide a systematic literature review of the different testicular sperm aspiration techniques, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement recommendations. MATERIALS AND METHODS: We prospectively collected data between March 2017 and June 2018...
January 2019: World Journal of Men's Health
https://read.qxmd.com/read/30358184/c-type-natriuretic-peptide-natriuretic-peptide-receptor-2-is-involved-in-cell-proliferation-and-testosterone-production-in-mouse-leydig-cells
#18
Lei Yang, Lanjie Lei, Qihan Zhao, Ying Gong, Gaopeng Guan, Shaoxin Huang
PURPOSE: This study investigated the role of natriuretic peptide receptor 2 (NPR2) on cell proliferation and testosterone secretion in mouse Leydig cells. MATERIALS AND METHODS: Mouse testis of different postnatal stages was isolated to detect the expression C-type natriuretic peptide (CNP) and its receptor NPR2 by quantitative reverse transcription polymerase chain reaction (RT-qPCR). Leydig cells isolated from mouse testis were cultured and treated with shNPR2 lentiviruses or CNP...
October 23, 2018: World Journal of Men's Health
https://read.qxmd.com/read/30350487/microtubular-dysfunction-and-male-infertility
#19
REVIEW
Sezgin Gunes, Pallav Sengupta, Ralf Henkel, Aabed Alguraigari, Mariana Marques Sinigaglia, Malik Kayal, Ahmad Joumah, Ashok Agarwal
Microtubules are the prime component of the cytoskeleton along with microfilaments. Being vital for organelle transport and cellular divisions during spermatogenesis and sperm motility process, microtubules ascertain functional capacity of sperm. Also, microtubule based structures such as axoneme and manchette are crucial for sperm head and tail formation. This review (a) presents a concise, yet detailed structural overview of the microtubules, (b) analyses the role of microtubule structures in various male reproductive functions, and (c) presents the association of microtubular dysfunctions with male infertility...
October 22, 2018: World Journal of Men's Health
https://read.qxmd.com/read/30350486/metabolic-syndrome-and-male-fertility
#20
REVIEW
Ana Dias Martins, Ahmad Majzoub, Ashok Agawal
Metabolic syndrome (MetS) represents a cluster of conditions that have a negative impact on human health overall. Its prevalence has been rapidly increasing worldwide and has coincided with a global decrease in birth rates and fertility potential. This review aims to address this observation through studying the relationship between MetS and male reproductive health. The effects of obesity, dyslipidemia, hypertension, and insulin resistance on male fertility were examined and supporting evidence explaining the pathophysiology of sperm dysfunction with each MetS component were described...
October 22, 2018: World Journal of Men's Health
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