journal
https://read.qxmd.com/read/38535614/-blastocystis-spp-and-other-intestinal-parasites-in-polish-soldiers-deployed-to-lebanon-and-iraq
#1
JOURNAL ARTICLE
Danuta Izabela Kosik-Bogacka, Krzysztof Korzeniewski, Natalia Łanocha-Arendarczyk, Joanna Korycińska, Małgorzata Lepczyńska, Ewa Dzika, Małgorzata Marchelek-Myśliwiec
Intestinal parasitic infections are one of the most common infectious diseases worldwide, particularly in developing countries. A distinct group at increased risk of infection is military personnel deployed overseas for extended periods, typically six months at a time. The aim of this study was to determine the prevalence of Blastocystis spp. and other intestinal parasites in Polish military personnel returning from deployments to Lebanon (n = 206) and Iraq (n = 220). In this group of subjects, we found Blastocystis spp...
March 21, 2024: Pathogens
https://read.qxmd.com/read/38535613/vector-borne-and-zoonotic-pathogens-in-raccoon-dogs-nyctereutes-procyonoides-and-raccoons-procyon-lotor-from-schleswig-holstein-germany
#2
JOURNAL ARTICLE
Jana C Klink, Alexandra Rieger, Peter Wohlsein, Ursula Siebert, Anna Obiegala
Raccoon dogs ( Nyctereutes procyonoides ) and raccoons ( Procyon lotor ) are invasive alien species originating from East Asia and North America, respectively. They are discussed as vectors and reservoirs for various infectious diseases, including vector-borne and zoonotic pathogens, and are therefore a potential threat to human and domestic animal health, as well as to biodiversity and conservation. In the years 2021 and 2022, 110 raccoon dogs ( Nyctereutes procyonoides ) and 30 raccoons ( Procyon lotor ) were screened via qPCR for the presence of Leptospira spp...
March 21, 2024: Pathogens
https://read.qxmd.com/read/38535612/fungemia-by-wickerhamomyces-anomalus-a-narrative-review
#3
REVIEW
Petros Ioannou, Stella Baliou, Diamantis P Kofteridis
Wickerhamomyces anomalus has been previously classified as Hansenula anomala , Pichia anomala , and Candida pelliculosa and was recently reclassified in the genus Wickerhamomyces after phylogenetic analysis of its genetic sequence. An increasing number of reports of human infections by W. anomalus have emerged, suggesting that this microorganism is an emerging pathogen. The present review aimed to provide data on the epidemiology, antifungal resistance, clinical characteristics, treatment, and outcomes of fungemia by W...
March 21, 2024: Pathogens
https://read.qxmd.com/read/38535611/community-directed-vector-control-to-accelerate-onchocerciasis-elimination
#4
REVIEW
Benjamin Jacob, Edwin Michael, Thomas R Unnasch
Onchocerciasis, or river blindness, has historically been one of the most important causes of blindness worldwide, and a major cause of socio-economic disruption, particularly in sub-Saharan Africa. Its importance as a cause of morbidity and an impediment to economic development in some of the poorest countries in the world motivated the international community to implement several programs to control or eliminate this scourge. Initially, these involved reducing transmission of the causative agent Onchocerca volvulus through controlling the vector population...
March 21, 2024: Pathogens
https://read.qxmd.com/read/38535610/the-course-of-covid-19-and-long-covid-identifying-risk-factors-among-patients-suffering-from-the-disease-before-and-during-the-omicron-dominant-period
#5
JOURNAL ARTICLE
Mateusz Babicki, Damian Kołat, Żaneta Kałuzińska-Kołat, Joanna Kapusta, Agnieszka Mastalerz-Migas, Piotr Jankowski, Michał Chudzik
SARS-CoV-2 has acquired many mutations that influence the severity of COVID-19's course or the risk of developing long COVID. In 2022, the dominant SARS-CoV-2 variant was Omicron. This study aimed to compare the course of COVID-19 in the periods before and during the dominance of the Omicron variant. Risk factors for developing long COVID were also assessed. This study was based on stationary visits of patients after COVID-19 and follow-up assessments after 3 months. Clinical symptoms, comorbidities, and vaccination status were evaluated in 1967 patients...
March 20, 2024: Pathogens
https://read.qxmd.com/read/38535609/regulation-of-autophagosome-lysosome-fusion-by-human-viral-infections
#6
REVIEW
Po-Yuan Ke
Autophagy plays a fundamental role in maintaining cellular homeostasis by eliminating intracellular components via lysosomes. Successful degradation through autophagy relies on the fusion of autophagosomes to lysosomes, which leads to the formation of autolysosomes containing acidic proteases that degrade the sequestered materials. Viral infections can exploit autophagy in infected cells to balance virus-host cell interactions by degrading the invading virus or promoting viral growth. In recent years, cumulative studies have indicated that viral infections may interfere with the fusion of autophagosomes and lysosomes, thus benefiting viral replication and associated pathogenesis...
March 20, 2024: Pathogens
https://read.qxmd.com/read/38535608/beau-s-lines-and-covid-19-a-systematic-review-on-their-association
#7
REVIEW
Aris P Agouridis, Christina Mastori-Kourmpani, Polyna Antoniou, Paschalis Konstantinou, Evangelos C Rizos, Constantinos Tsioutis
BACKGROUND: Beau's lines are transverse grooves in the nail plate that result from transient interruption of the growth of the proximal nail matrix after severe disease. The aim of this study is to systematically report all evidence on the association of Beau's lines with COVID-19 infection or vaccination against COVID-19. METHODS: PubMed and Scopus databases were searched up to January 2024 for articles reporting Beau's lines associated with COVID-19 infection or vaccination for COVID-19...
March 20, 2024: Pathogens
https://read.qxmd.com/read/38535607/metagenomic-detection-and-genetic-characterization-of-human-sapoviruses-among-children-with-acute-flaccid-paralysis-in-nigeria
#8
JOURNAL ARTICLE
Uwem Etop George, Temitope O C Faleye, Lander De Coninck, Sheriff Tunde Agbaje, Ijeoma Maryjoy Ifeorah, Bernard Anyebe Onoja, Elijah Igbekele Oni, Adebowale Oluseyi Olayinka, Toluwani Goodnews Ajileye, Arthur Obinna Oragwa, Toluwanimi Emmanuel Akinleye, Bolutife Olubukola Popoola, Oluwadamilola Gideon Osasona, Olaitan Titilola Olayinka, Oluwadamilola Adefunke George, Ahmed Iluoreh Muhammad, Isaac Komolafe, Adekunle Johnson Adeniji, Jelle Matthijnssens, Moses Olubusuyi Adewumi
Using a metagenomic sequencing approach on stool samples from children with Acute Flaccid Paralysis (AFP), we describe the genetic diversity of Sapoviruses (SaVs) in children in Nigeria. We identified six complete genome sequences and two partial genome sequences. Several SaV genogroups and genotypes were detected, including GII (GII.4 and GII.8), GIV (GIV.1), and GI (GI.2 and GI.7). To our knowledge, this is the first description of SaV infections and complete genomes from Nigeria. Pairwise identity and phylogenetic analysis showed that the Nigerian SaVs were related to previously documented gastroenteritis outbreaks with associated strains from China and Japan...
March 19, 2024: Pathogens
https://read.qxmd.com/read/38535606/recent-advances-in-the-epidemiology-of-pathogenic-agents
#9
EDITORIAL
Wei-Chuan Chen, Yusen Eason Lin
The COVID-19 pandemic has underscored the pivotal role of epidemiology in studying pathogenic agents [...].
March 19, 2024: Pathogens
https://read.qxmd.com/read/38535605/genetic-diversity-of-trypanosomes-infesting-cattle-from-savannah-district-in-north-of-c%C3%A3-te-d-ivoire-using-conserved-genomic-signatures-rrna-its1-and-ggapdh
#10
JOURNAL ARTICLE
Jean-Yves Ekra, Eliakunda Michael Mafie, Edouard K N'Goran, Dramane Kaba, Biégo Guillaume Gragnon, Jagan Srinivasan
The potential danger to livestock from African animal trypanosomiasis is well known. However, the trypanosome species circulating in cattle and their genetics are poorly understood. After different alignments according to three regions (ITS1, gGAPDH and rRNA gene) of the trypanosome genome, phylogenetic analyses were used to show the genetic diversity of the different species that were circulating in the cattle in three regions (Bagoue, Poro and Tchologo) of Côte d'Ivoire. These analyses were performed by alignment of ITS1; by alignment of partial 18S, ITS1, 5...
March 19, 2024: Pathogens
https://read.qxmd.com/read/38535604/genome-sequencing-of-historical-encephalomyocarditis-viruses-from-south-africa-links-the-historical-1993-4-savanna-elephant-loxodonta-africana-outbreak-to-cryptic-mastomys-rodents
#11
JOURNAL ARTICLE
Vanessa van Meer, Janusz T Pawęska, Robert Swanepoel, Antoinette Grobbelaar, Armanda D Bastos
From 1993 to 1994, 64 free-ranging elephants ( Loxodonta africana ) succumbed to encephalomyocarditis in the Kruger National Park, South Africa, of which 83% were adult bulls. Mastomys rodents were implicated as the reservoir host of the Encephalomyocarditis virus (EMCV) based on serology and RT-PCR. However, in the absence of sequence-confirmation of both the virus and the rodent host, definitive links between the elephant outbreak strains and rodent reservoir could not be established. In this study, we generate the first reference genome sequences for three historical EMCVs isolated from two Mastomys rodents and one Mastomys -associated mite, Laelaps muricola , in Gauteng Province, South Africa, in 1961...
March 19, 2024: Pathogens
https://read.qxmd.com/read/38535603/obtaining-microbiologically-safe-hatching-eggs-from-hatcheries-using-essential-oils-for-integrated-sanitization-strategies-in-hatching-eggs-poultry-houses-and-poultry
#12
REVIEW
Gabriel da Silva Oliveira, Concepta McManus, Igor Rafael Ribeiro Vale, Vinícius Machado Dos Santos
Essential oils are liquids containing non-toxic compounds that are unfavorable to the growth of microorganisms. They are sold globally at affordable or very high prices, depending on the availability and type of plant, the scale of production, the extraction method, costs associated with logistics and electricity consumption, among other variables. Each year, the quantity of research dedicated to the antimicrobial potential of essential oils in poultry farming is expanding. Researchers consensually relay that this increase is due to the growing resistance of microorganisms to traditional antimicrobials and concerns about the toxicity of these products...
March 18, 2024: Pathogens
https://read.qxmd.com/read/38535602/infections-in-disorders-of-immune-regulation
#13
REVIEW
Abarna Thangaraj, Reva Tyagi, Deepti Suri, Sudhir Gupta
Primary immune regulatory disorders (PIRDs) constitute a spectrum of inborn errors of immunity (IEIs) that are primarily characterized by autoimmunity, lymphoproliferation, atopy, and malignancy. In PIRDs, infections are infrequent compared to other IEIs. While susceptibility to infection primarily stems from antibody deficiency, it is sometimes associated with additional innate immune and T or NK cell defects. The use of immunotherapy and chemotherapy further complicates the immune landscape, increasing the risk of diverse infections...
March 17, 2024: Pathogens
https://read.qxmd.com/read/38535601/an-entomological-investigation-during-a-recent-rift-valley-fever-epizootic-epidemic-reveals-new-aspects-of-the-vectorial-transmission-of-the-virus-in-madagascar
#14
JOURNAL ARTICLE
Luciano Michaël Tantely, Soa Fy Andriamandimby, Maminirina Fidelis Ambinintsoa, Manou Rominah Raharinirina, Jean Théophile Rafisandratantsoa, Jean-Pierre Ravalohery, Aina Harimanana, Nirina Nantenaina Ranoelison, Judickaelle Irinantenaina, Miamina Fidy Ankasitrahana, Dany Bakoly Ranoaritiana, Laurence Randrianasolo, Rindra Vatosoa Randremanana, Vincent Lacoste, Philippe Dussart, Romain Girod
A Rift Valley fever (RVF) outbreak occurred in at least five regions of Madagascar in 2021. The aim of this study was to provide an overview of the richness, abundance, ecology, and trophic preferences of mosquitoes in the Mananjary district and to investigate the distribution of mosquitoes that were RT-PCR-positive for RVFV. Three localities were prospected from 26 April to 4 May 2021, using light traps, BG-Sentinel traps baited with an artificial human odor, Muirhead-Thomson pit traps, and indoor pyrethroid spray catches...
March 16, 2024: Pathogens
https://read.qxmd.com/read/38535600/the-re-emergence-of-rift-valley-fever-in-mananjary-district-madagascar-in-2021-a-call-for-action
#15
JOURNAL ARTICLE
Aina Nirina Harimanana, Soa Fy Andriamandimby, Dany Bakoly Ranoaritiana, Laurence Randrianasolo, Judickaelle Irinantenaina, Nirina Nantenaina Ranoelison, Jean Théophile Rafisandrantatsoa, Miamina Fidy Ankasitrahana, Antso Hasina Raherinandrasana, Manuela Vololoniaina Andriamahatana, Michael Luciano Tantely, Romain Girod, Philippe Dussart, Vincent Lacoste, Rindra Vatosoa Randremanana
An epizootic of rift valley fever (RVF) was suspected on 21 February 2021 in various districts of Madagascar, with a lab confirmation on 1 April 2021. A cross-sectional survey aiming to detect cases of RVF in humans and to study the circulation of rift valley fever virus (RVFV) in animals was conducted from 22 April to 4 May 2021 in the district of Mananjary. Blood samples from cattle and humans were tested using serological and molecular techniques. In cattle, the circulation of RVFV was confirmed between 5 February and 4 May 2021...
March 16, 2024: Pathogens
https://read.qxmd.com/read/38535599/alterations-in-n-glycosylation-of-hcv-e2-protein-in-children-patients-with-ifn-rbv-therapy-failure
#16
JOURNAL ARTICLE
Karolina Zimmer, Alicja M Chmielewska, Paulina Jackowiak, Marek Figlerowicz, Krystyna Bienkowska-Szewczyk
The glycosylation of viral envelope proteins plays an important role in virus biology and the immune response of the host to infection. Hepatitis C virus (HCV) envelope proteins E1 and E2, key players in virus entry and spread, are highly N-glycosylated and possess 4 (5 in certain genotypes) to 11 conserved glycosylation sites, respectively. Many published results based on recombinant proteins indicate that the glycan shield can mask the epitopes targeted by neutralizing antibodies. Glycan shifting within the conserved linear E2 region (412-423) could be one of the escape strategies used by HCV...
March 15, 2024: Pathogens
https://read.qxmd.com/read/38535598/the-zoonotic-angiostrongylus-cantonensis-and-the-veterinary-parasite-aelurostrongylus-abstrusus-infecting-terrestrial-gastropods-from-urban-areas-of-macap%C3%A3-brazilian-amazon-region
#17
JOURNAL ARTICLE
Tatiane Alves Barbosa, Silvana Carvalho Thiengo, Monica Ammon Fernandez, Jucicleide Ramos-de-Souza, Suzete Rodrigues Gomes
Metastrongyloidea includes nematodes that parasitize mammals, mainly infecting their respiratory and cardiovascular systems, and are responsible for emerging zoonosis in the world. Terrestrial mollusks are their main intermediate hosts, with few exceptions. Here we present the results of a malacological survey to know the distribution of Angiostrongylus cantonensis in Macapá, Amapá, in the Brazilian Amazon region, after the report of a case of eosinophilic meningitis in 2018. Mollusks were collected in 45 neighborhoods between March 2019 and February 2020...
March 15, 2024: Pathogens
https://read.qxmd.com/read/38535597/challenges-in-toxocariasis-diagnosis-from-pericarditis-through-hepatic-tumor-to-the-detection-of-brain-aneurysms-case-report
#18
Martyna Biała, Joanna Nieleńczuk, Anna Chodorowska, Bartosz Szetela
Toxocariasis is the parasitic infection caused by the larvae of Toxocara roundworms species: Toxocara canis from dogs and, less frequently, Toxocara cati from cats. The high proportion of asymptomatic cases of toxocariasis and the uncharacteristic clinical manifestations mimicking other medical conditions make diagnosis challenging. The main clinical presentations of toxocariasis are visceral and ocular larva migrans. Migration to the central nervous system (neurotoxocariasis) is rare and can cause meningitis, encephalitis, myelitis, cerebral vasculitis, seizures, headache or asymptomatic CNS infection...
March 15, 2024: Pathogens
https://read.qxmd.com/read/38535596/the-influence-of-l-lysine-alpha-oxidase-on-the-biofilm-formation-of-opportunistic-microorganisms-associated-with-inflammatory-diseases-of-the-urinary-tract
#19
JOURNAL ARTICLE
Alexandr Senyagin, Nadezhda Sachivkina, Milana Das, Anna Arsenyuk, Ramziya Mannapova, Alfir Mannapov, Tursumbai Kubatbekov, Dmitriy Svistunov, Olesya Petrukhina, Andrey Zharov, Natallia Zhabo
Urinary tract infections occupy a special niche among diseases of infectious etiology. Many microorganisms associated with urinary tract infections, such as Klebsiella oxytoca , Enterococcus spp., Morganella morganii , Moraxella catarrhalis , Pseudomonas aeruginosa , Proteus mirabilis , Staphylococcus aureus , Staphylococcus spp., and Candida spp., can form biofilms. The aim of this research was to study the effect of the enzyme L-lysine-Alpha-oxidase (LO) produced by the fungus Trichoderma harzianum Rifai on the biofilm formation process of microorganisms associated with urinary tract infections...
March 15, 2024: Pathogens
https://read.qxmd.com/read/38535595/epidemiology-clinical-signs-and-risk-factors-associated-with-theileriosis-in-australian-cattle-2006-2022
#20
JOURNAL ARTICLE
Emily Onizawa, Cheryl Jenkins
For over a decade, bovine anaemia caused by Theileria orientalis Ikeda has been a significant disease in the Australian cattle industry. In this study, we conducted a spatial and temporal analysis of theileriosis in Australia using historic data from submissions to the New South Wales Department of Primary Industries (NSW DPI) from 2006 to 2022, where herd history, clinical signs, and PCR results were available. Since the first detections of bovine theileriosis in the Sydney area in 2006, the disease spread north- and southward and is now endemic to the southeast coast of Australia, closely mirroring the distribution of the principal vector Haemaphysalis longicornis...
March 15, 2024: Pathogens
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