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JOURNAL ARTICLE
Natalie Saremi, Katherine A Lewis, Jeffrey D Klausner
No abstract text is available yet for this article.
April 12, 2024: Journal of the Pediatric Infectious Diseases Society
#2
JOURNAL ARTICLE
Stanley Plotkin
No abstract text is available yet for this article.
April 10, 2024: Journal of the Pediatric Infectious Diseases Society
#3
JOURNAL ARTICLE
Alison Rousseau, Eric McGrath, Laura Benjamins, Salome Cockern, Jill Meade, Keshaum Houston, Melina Breaux, Elizabeth Secord
Nineteen youth living with HIV (YLWH) opted for injectable cabotegravir and rilpivirine without oral lead in and without achieving an undetectable HIV viral load (VL) for the 3 months prior to initiation. All achieved undetectable status within 3 months (3 injections) and maintained an undetectable status through 6-12 months of therapy.
April 9, 2024: Journal of the Pediatric Infectious Diseases Society
#4
JOURNAL ARTICLE
Naseem Ravanbakhsh, Catherine A Chapin, Yun Li, Ravi Jhaveri
For patients with Biliary atresia, antibiotic prophylaxis after Kasai portoenterostomy is a common practice. Societal guidelines often cite one reference as supportive evidence for this practice. In this paper, we go back to review the quality of this evidence and suggest more research is required to demonstrate the efficacy of antibiotic prophylaxis in this population.
April 8, 2024: Journal of the Pediatric Infectious Diseases Society
#5
JOURNAL ARTICLE
Amir M Mohareb, Miriam Deukmejian, Cesar Guerra Castillo, Tyler S Brown, Regina LaRocque, Elsie Taveras, Priya Sarin Gupta
No abstract text is available yet for this article.
April 8, 2024: Journal of the Pediatric Infectious Diseases Society
#6
JOURNAL ARTICLE
Rana E El Feghaly, Preeti Jaggi, Sophie E Katz, Nicole M Poole
Acute respiratory tract infections (ARTIs) account for most antibiotic prescriptions in pediatrics. Although US guidelines continue to recommend ≥10 days antibiotics for common ARTIs, evidence suggests that 5-day courses can be safe and effective. Academic imprinting seems to play a major role in the continued use of prolonged antibiotic durations. In this report, we discuss the evidence supporting short antibiotic courses for group A streptococcal pharyngitis, acute otitis media, and acute bacterial rhinosinusitis...
April 6, 2024: Journal of the Pediatric Infectious Diseases Society
#7
JOURNAL ARTICLE
Asif Noor, Leonard R Krilov
The efforts to prevent RSV infection in infants span over half a century. RSV vaccine development began in the 1960s, and it confronted a significant disappointment after testing a formalin inactivated RSV (FI RSV) vaccine candidate. This inactivated RSV vaccine was not protective. A large number of the vaccinated RSV naïve children, when subsequently exposed to natural RSV infection from wild type virus in the community, developed severe lung inflammation termed enhanced respiratory disease. This resulted in a halt in RSV vaccine development...
April 5, 2024: Journal of the Pediatric Infectious Diseases Society
#8
JOURNAL ARTICLE
New and Emerging Passive Immunization Strategies for the Prevention of RSV Infection During Infancy.
Joseph B Domachowske
To date, safe and effective strategies to prevent medically attended RSV illness across the infant population have been limited to passive immunoprophylaxis for those at highest risk. While active vaccination strategies are finally available to protect adults 60 years and older from serious RSV infection, safe and effective vaccines for use in children have yet to emerge. In contrast, passive immunization strategies designed to protect all infants against RSV has finally met with success, with two new strategies approved by the United States Food and Drug Administration during the second half of 2023...
March 30, 2024: Journal of the Pediatric Infectious Diseases Society
#9
JOURNAL ARTICLE
Ashleah Courtney, Gregory Cook, Margarita Silio
Acute bacterial upper respiratory infections are common indications for antibiotics in pediatrics, and many prescriptions may be inappropriate. Novel approaches to outpatient antimicrobial stewardship interventions are needed. This quasi-experimental study of an order set and best practice advisory alert targeting cefdinir prescriptions demonstrated an 8.4% decrease in cefdinir prescribing (p=<0.001).
March 23, 2024: Journal of the Pediatric Infectious Diseases Society
#10
JOURNAL ARTICLE
Alexander E Johnson, Aditi Upadhye, Veronicah Knight, Erik L Gaskin, Lindsey B Turnbull, David Ayuku, Mark Nyalumbe, Emily Abuonji, Chandy C John, Megan S McHenry, Tuan M Tran, George Ayodo
BACKGROUND: Subclinical inflammation and cognitive deficits have been separately associated with asymptomatic Plasmodium falciparum infections in schoolchildren. However, whether parasite-induced inflammation is associated with worse cognition has not been addressed. We conducted a cross-sectional pilot study to better assess the effect of asymptomatic P. falciparum parasitemia and inflammation on cognition in Kenyan schoolchildren. METHODS: We enrolled 240 children aged 7-14 years residing in high malaria transmission in Western Kenya...
March 21, 2024: Journal of the Pediatric Infectious Diseases Society
#11
JOURNAL ARTICLE
Alice Lehman, Lea Goren, Michael D Evans, Olivia Toles, Daniel Drozdov, Shannon Andrews, Shane McAllister, Beth K Thielen
No abstract text is available yet for this article.
March 14, 2024: Journal of the Pediatric Infectious Diseases Society
#12
JOURNAL ARTICLE
Brooke Baker, Frances Hung, Michael J Smith, Alaattin Erkanli, Katherine Greenhill, Jillian Hayes, Alice Parish, Grace Zhou, Ganga S Moorthy, Connor R Deri
Observational studies in adults suggest nasal methicillin-resistant Staphylococcus aureus (MRSA) swabs have a high negative predictive value (NPV) for ruling out MRSA pneumonia, however pediatric data are limited. This retrospective study of 505 pediatric patients found a 99.8% NPV among children with suspected respiratory infections.
March 11, 2024: Journal of the Pediatric Infectious Diseases Society
#13
JOURNAL ARTICLE
Jenna H Tan, Caitlin L McGrath, Adam W Brothers, Yasaman Fatemi, Victoria Konold, Daniel Pak, Scott J Weissman, Danielle M Zerr, Matthew P Kronman
We sought to evaluate whether children hospitalized with acute respiratory infections experienced differences in antibiotic use by race and ethnicity. We found that likelihood of broad-spectrum antibiotic receipt differed across racial and ethnic groups. Future work should confirm this finding, evaluate causes, and ensure equitable antibiotic use.
March 8, 2024: Journal of the Pediatric Infectious Diseases Society
#14
JOURNAL ARTICLE
Jérémie F Cohen, Robert R Tanz, Stanford T Shulman
The most common cause of bacterial pharyngitis is Group A Streptococcus (GAS). Accurate diagnosis of GAS pharyngitis is crucial to identify children who would benefit from antibiotic treatment. Rapid diagnosis has the potential to reduce antibiotic overuse. Current national guidelines differ in their recommendations for GAS testing. While rapid antigen detection tests are widely used, their sensitivity is considered too low for stand-alone testing by several expert bodies. Newer molecular tests using nucleic acid amplification show higher accuracy and fast results, but their cost, complexity, and very high sensitivity may limit widespread adoption...
March 8, 2024: Journal of the Pediatric Infectious Diseases Society
#15
JOURNAL ARTICLE
Ardythe L Morrow, Daniel C Payne, Shannon C Conrey, Meredith McMorrow, Monica M McNeal, Liang Niu, Allison R Burrell, Elizabeth P Schlaudecker, Claire Mattison, Rachel M Burke, Emily DeFranco, Zheyi Teoh, Jens Wrammert, Lydia J Atherton, Natalie J Thornburg, Mary A Staat
BACKGROUND: The endemic coronaviruses OC43, HKU1, NL63 and 229E cause cold-like symptoms and are related to SARS-CoV-2, but their natural histories are poorly understood. In a cohort of children followed from birth to 4 years, we documented all coronavirus infections, including SARS-CoV-2, to understand protection against subsequent infections with the same virus (homotypic immunity) or a different coronavirus (heterotypic immunity). METHODS: Mother-child pairs were enrolled in metropolitan Cincinnati during the third trimester of pregnancy in 2017-18...
March 5, 2024: Journal of the Pediatric Infectious Diseases Society
#16
JOURNAL ARTICLE
Priya Mallikarjuna, Nicholas DeFelice, Matthew J Ward, Jose A Suarez, Juan David Ramirez, Alberto Paniz Mondolfi
No abstract text is available yet for this article.
March 4, 2024: Journal of the Pediatric Infectious Diseases Society
#17
JOURNAL ARTICLE
James D Cherry
Measles is a vaccine preventable illness. Nevertheless, in recent years, measles is still endemic and epidemic in both the developed world and the developing world. The public perception of measles in the past was that it was not a big deal. However, measles is associated with a number of complications which can be places in three categories which are: acute(diarrhea, otitis media, pneumonia, encephalitis, seizures, and death) and delayed-subacute sclerosing panencephalitis (SSPE) and post measles immune amnesia...
February 29, 2024: Journal of the Pediatric Infectious Diseases Society
#18
JOURNAL ARTICLE
Todd A Florin, Stephen B Freedman, Jianling Xie, Anna L Funk, Daniel J Tancredi, Kelly Kim, Mark I Neuman, Adriana Yock-Corrales, Kelly R Bergmann, Kristen A Breslin, Yaron Finkelstein, Fahd A Ahmad, Usha R Avva, Maren M Lunoe, Pradip P Chaudhari, Nipam P Shah, Amy C Plint, Vikram J Sabhaney, Usha Sethuraman, Michael A Gardiner, Laura F Sartori, Bruce Wright, Nidhya Navanandan, Santiago Mintegi, Iker Gangoiti, Meredith L Borland, Shu-Ling Chong, Maria Y Kwok, Michelle Eckerle, Naveen Poonai, Carlos Miguel Angelats Romero, Muhammad Waseem, Jasmine R Nebhrajani, Maala Bhatt, Kerry Caperell, Carmen Campos, Sarah M Becker, Claudia R Morris, Alexander J Rogers, April J Kam, Viviana Pavlicich, Laura Palumbo, Stuart R Dalziel, Andrea K Morrison, Pedro B Rino, Jonathan C Cherry, Marina I Salvadori, Lilliam Ambroggio, Terry P Klassen, Daniel C Payne, Richard Malley, Norma-Jean Simon, Nathan Kuppermann
No abstract text is available yet for this article.
February 23, 2024: Journal of the Pediatric Infectious Diseases Society
#19
JOURNAL ARTICLE
Zheyi Teoh, Shannon Conrey, Monica McNeal, Allison Burrell, Rachel M Burke, Claire P Mattison, Meredith McMorrow, Natalie Thornburg, Daniel C Payne, Ardythe L Morrow, Mary Allen Staat
BACKGROUND: Respiratory viral shedding is incompletely characterized by existing studies due to the lack of longitudinal nasal sampling and limited inclusion of healthy/asymptomatic children. We describe characteristics associated with prolonged virus detection by PCR in a community-based birth cohort. METHODS: Children were followed from birth to 2 years of age in the PREVAIL cohort. Weekly nasal swabs were collected and tested using the Luminex Respiratory Pathogen Panel...
February 15, 2024: Journal of the Pediatric Infectious Diseases Society
#20
JOURNAL ARTICLE
Ivan F Gutierrez-Tobar, Claudia Beltran-Arroyave, Juan P Rojas-Hernandez, Andres F Arias-Sanchez, Juan P Londoño, Julián C Galvis-Ayala
No abstract text is available yet for this article.
February 13, 2024: Journal of the Pediatric Infectious Diseases Society
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