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Journals Hepatic Medicine : Evidence an...

Hepatic Medicine : Evidence and Research

https://read.qxmd.com/read/37013139/covid-associated-cast-forming-cholangiopathy-a-commentary-on-disease-mechanism-treatment-and-prognosis
#21
JOURNAL ARTICLE
Yara Sarkis, Nasir Saleem, Raj Vuppalanchi, Mark Gromski
The complete impact of COVID-19 infection continues to develop since the onset of the COVID-19 pandemic. COVID-19 cholangiopathy has been recently described in a subset of patients who recovered from severe COVID-19 infection. The most common phenotype of patients suffering from COVID-19 cholangiopathy had severe infection requiring a stay in the intensive care unit, mechanical ventilation and vasopressor medications. Patients with COVID-cholangiopathy present with severe and prolonged cholestatic liver injury...
2023: Hepatic Medicine: Evidence and Research
https://read.qxmd.com/read/36938483/factors-associated-with-in-hospital-mortality-in-malagasy-patients-with-acute-decompensation-of-liver-cirrhosis-a-retrospective-cohort
#22
JOURNAL ARTICLE
Chantelli Iamblaudiot Razafindrazoto, Nitah Harivony Randriamifidy, Behoavy Mahafaly Ralaizanaka, Jean Tsitamita Andrianoelison, Haga Tsilavo Ravelomanantsoa, Mialitiana Rakotomaharo, Domoina Harivonjy Hasina Laingonirina, Sonny Maherison, Jolivet Auguste Rakotomalala, Anjaramalala Sitraka Rasolonjatovo, Andry Lalaina Rinà Rakotozafindrabe, Tovo Harimanana Rabenjanahary, Soloniaina Hélio Razafimahefa, Rado Manitrala Ramanampamonjy
BACKGROUND: Cirrhosis is a pathology responsible for a significant hospital morbidity and mortality. The objective of this study was to determine the factors associated with hospital mortality in a sample of Malagasy cirrhotics. PATIENTS AND METHODS: This was a retrospective cohort study from January 2018 to August 2020 conducted in the Hepato-Gastroenterology Unity, University Hospital Joseph Raseta Befelatanana, Antananarivo, Madagascar. RESULTS: One hundred and eight patients were included...
2023: Hepatic Medicine: Evidence and Research
https://read.qxmd.com/read/36923368/medicinal-plants-used-for-the-management-of-hepatitis-over-the-past-15-years-in-ethiopia-a-systematic-review
#23
REVIEW
Yibeltal Aschale, Bantayehu Addis Tegegne, Wubetu Yihunie
BACKGROUND: Treatment of human and animal ailments using botanical sources has obtained significant attention in Ethiopia. The compounds available in plants comprise a plentiful source of bioactive ingredients able to treat many complications. The review aimed to present an updated list of plants used for managing hepatitis over the past 15 years in Ethiopia. METHODS: Systematic, comprehensive search was undertaken from electronic databases (PubMed, Google Scholar, Science Direct, and Scopus) between September 01 and October 15, 2022, using standard search terms...
2023: Hepatic Medicine: Evidence and Research
https://read.qxmd.com/read/36852138/covid-19-associated-liver-injury
#24
REVIEW
Daniel T Gildea, Stephanie M Woo, Corinne E O'Connor, Amol S Rangnekar
This review analyzes data regarding liver injury associated with COVID-19 infection. We discuss reported effects on the liver from both COVID-19 and COVID-19 treatment as well as pathophysiology, review the potential role of drug-induced liver injury as an etiology of COVID-19-associated liver injury, and touch on other reports of significant outcomes including COVID-19 cholangiopathy and autoimmune hepatitis. Finally, we review the implications of COVID-19 infection in liver transplant recipients.
2023: Hepatic Medicine: Evidence and Research
https://read.qxmd.com/read/36320211/perspectives-on-sarcopenia-as-a-predictor-for-outcomes-in-pediatric-patients-with-chronic-liver-disease
#25
REVIEW
Connie Chen, Mary Ayers, Judy H Squires, James E Squires
Sarcopenia, a pathologic deficiency of muscle mass and function, has emerged as an important secondary feature of many chronic disease states. For adults with end stage liver disease, there are multiple mechanisms which contribute to sarcopenia and its presence has proven to be an important predictor of morbidity and mortality. In children, there are only a limited number of reports which investigate the role of sarcopenia in liver disease. These studies, which are discussed and summarized in this review, report small, single-center analyses with dissimilar study cohorts and varying clinical definitions...
2022: Hepatic Medicine: Evidence and Research
https://read.qxmd.com/read/36304917/prevalence-and-factors-associated-with-hepatitis-b-infection-among-outpatient-adults-in-south-western-uganda
#26
JOURNAL ARTICLE
Elias Rugaatwa Ndibarema, Ronald Olum, David Ayebare, Jerome Kabakyenga
Background: About 2 billion people in the world are exposed to hepatitis B virus. Africa contributes 25% of the global Hepatitis B burden and prevalence in Uganda is 4.3%. Routine testing to establish the burden, improve prevention and control through early diagnosis and management are rare in hospital settings. We aimed at establishing the prevalence and factors associated with hepatitis B infection among adults attending outpatient clinic at Mbarara Regional Referral Hospital (MRRH) in Uganda...
2022: Hepatic Medicine: Evidence and Research
https://read.qxmd.com/read/36200122/polycystic-liver-disease-pathophysiology-diagnosis-and-treatment
#27
REVIEW
Luiz Fernando Norcia, Erika Mayumi Watanabe, Pedro Tadao Hamamoto Filho, Claudia Nishida Hasimoto, Leonardo Pelafsky, Walmar Kerche de Oliveira, Ligia Yukie Sassaki
Polycystic liver disease (PLD) is a clinical condition characterized by the presence of more than 10 cysts in the liver. It is a rare disease Of genetic etiology that presents as an isolated disease or assoc\iated with polycystic kidney disease. Ductal plate malformation, ciliary dysfunction, and changes in cell signaling are the main factors involved in its pathogenesis. Most patients with PLD are asymptomatic, but in 2-5% of cases the disease has disabling symptoms and a significant reduction in quality of life...
2022: Hepatic Medicine: Evidence and Research
https://read.qxmd.com/read/36171754/histopathological-evaluation-of-ethanolic-leaf-extract-of-lippia-adoensis-on-liver-kidney-and-biochemical-parameters-in-swiss-albino-mice
#28
JOURNAL ARTICLE
Abayneh Tunta Boye, Peter Etim Ekanem, Tesfamichael Berhe Hailu, Ifa Dereje Hordofa, Mulu Shiferaw Asfaw
Background: Eighty percent of Ethiopians use traditional medicine, one of which is the leaf of Lippea adoensis . Objective: To investigate subacute toxicity of aqueous extracts of L. adoensis leaves on the liver and kidney and biochemical parameters in Swiss albino mice. Methods: LD50 was assessed with nine experimental groups and one control group of adult female Swiss albino mice (five in each group). In the subacute study, 40 mice of both sexes were randomly divided into four groups of ten mice (both sexes) per group...
2022: Hepatic Medicine: Evidence and Research
https://read.qxmd.com/read/35971532/undiagnosed-seroprevalence-of-hepatitis-b-and-c-virus-infections-in-the-community-of-wolaita-zone-southern-ethiopia
#29
JOURNAL ARTICLE
Abera Kumalo, Takele Teklu, Tigistu Demisse, Abebe Anjulo
Background: Despite Ethiopia's hepatitis endemic status with intermediate to hyperendemic level, there is no national strategy for monitoring, preventing, and controlling viral hepatitis. In order to advise community-based intervention programs, studies on the magnitude, determinant factors, and understanding of indigenous social organization are important. Thus, this study examined undiagnosed seroprevalence and associated factors for HBV and HCV infections among community members in Wolaita Zone, Southern Ethiopia...
2022: Hepatic Medicine: Evidence and Research
https://read.qxmd.com/read/35936811/clinical-laboratory-and-bacterial-profile-of-spontaneous-bacterial-peritonitis-in-vietnamese-patients-with-liver-cirrhosis
#30
JOURNAL ARTICLE
Long Cong Nguyen, Thuy Thi-Bich Lo, Huong Dieu La, Ha Thi-Ngoc Doan, Ngoan Tran Le
Aim: To determine several clinical and laboratory features as well as the bacterial profile of spontaneous bacterial peritonitis (SBP) in 58 Vietnamese patients admitted to a single center due to liver cirrhosis. Methods: We retrospectively analyzed bacteriological, clinical and laboratory characteristics of patients with SBP admitted to the Gastroenterology and Hepatology Center from July 2019 to July 2020. Results: Out of a total 58 SBP patients, 41 (70...
2022: Hepatic Medicine: Evidence and Research
https://read.qxmd.com/read/35936810/current-perspectives-on-nucleos-t-ide-analogue-therapy-for-the-long-term-treatment-of-hepatitis-b-virus
#31
REVIEW
Teresa Broquetas, José A Carrión
The hepatitis B virus (HBV) infection remains a global public health problem. This review presents updated recommendations for the optimal current treatment of choice with nucleos(t)ide analogues (NA). Current clinical practice guidelines on the management of chronic hepatitis B (CHB) by the Asian Pacific Association for the Study of the Liver, the European Association for the Study of the Liver and the American Association for the Study of Liver Diseases have been considered. Patients with chronic HBV infection are at increased risk of liver disease progression to cirrhosis and hepatocellular carcinoma (HCC) development...
2022: Hepatic Medicine: Evidence and Research
https://read.qxmd.com/read/35611387/splenectomy-combined-with-endoscopic-variceal-ligation-evl-versus-evl-alone-for-secondary-prophylaxis-of-variceal-bleeding-in-hepatosplenic-schistosomiasis-a-retrospective-case-control-study
#32
JOURNAL ARTICLE
Jolivet Auguste Rakotomalala, Chantelli Iamblaudiot Razafindrazoto, Nitah Harivony Randriamifidy, Behoavy Mahafaly Ralaizanaka, Sonny Maherison, Domoina Harivonjy Hasina Laingonirina, Mialitiana Rakotomaharo, Anjaramalala Sitraka Rasolonjatovo, Mamisoa Anicet Rakotovao, Andry Lalaina Rinà Rakotozafindrabe, Tovo Harimanana Rabenjanahary, Rija Fanantenantsoa, Soloniaina Hélio Razafimahefa, Rado Manitrala Ramanampamonjy
Background: Hepatosplenic schistosomiasis (HSS) is one of the most common causes of portal hypertension in developing countries. Variceal bleeding is the most common cause of mortality during HSS. The objective of this study was to evaluate the efficacy of splenectomy associated with endoscopic variceal ligation (EVL) compared with EVL alone in preventing variceal bleeding in patients with HSS. Methods: This was a single-center, retrospective, case-control study...
2022: Hepatic Medicine: Evidence and Research
https://read.qxmd.com/read/35591850/prevalence-of-hiv-and-its-co-infection-with-hepatitis-b-c-virus-among-chronic-liver-disease-patients-in-ethiopia
#33
JOURNAL ARTICLE
Yayehyirad Tassachew, Tamrat Abebe, Yeshambel Belyhun, Tezazu Teffera, Abate Bane Shewaye, Hailemichael Desalegn, Henok Andualem, Abiy Kinfu, Andargachew Mulu, Adane Mihret, Rawleigh Howe, Abraham Aseffa
Background: The efficient use of antiretroviral drugs has significantly reduced AIDS-related morbidities and mortalities; however, mortality due to non-AIDS-related end-stage liver diseases is escalating in those living with HIV. Objective: The study was designed to determine the prevalence of HIV and its co-infection with HBV and HCV among chronic liver disease (CLD) patients in Ethiopia. Methods: Three hundred and forty-five CLD patients were included in this study in two groups: Hepatocellular carcinoma (HCC) (n=128) and non-HCC (n=217) patients...
2022: Hepatic Medicine: Evidence and Research
https://read.qxmd.com/read/35530746/post-marketing-surveillance-study-of-the-safety-and-efficacy-of-nalfurafine-capsules-2-5-%C3%AE-g-oral-dispersing-tablets-2-5-%C3%AE-g-in-1186-patients-with-chronic-liver-disease-and-intractable-pruritus
#34
JOURNAL ARTICLE
Hiroshi Yoshitani, Junko Ito, Hideki Kozono
Background: Nalfurafine (Remitch® , Toray Industries, Inc.) is a selective κ-receptor agonist approved in Japan for the improvement of pruritus in patients with chronic liver diseases (only when existing treatments bring insufficient efficacy) in May 2015. Methods: A post-marketing Specific Drug Use Survey was conducted in Japan (March 1, 2016 to June 30, 2020) of the safety and efficacy of nalfurafine for the improvement of pruritus in patients with chronic liver disease...
2022: Hepatic Medicine: Evidence and Research
https://read.qxmd.com/read/35514530/special-considerations-in-the-management-of-hiv-and-viral-hepatitis-coinfections-in-liver-transplantation
#35
REVIEW
Josiah D McCain, David M Chascsa
Modern therapies for hepatitis B virus, hepatitis C virus, and human immunodeficiency virus have become so effective that patients treated for these conditions can have normal life-expectancies. Suitable livers for transplantation remain a scarce and valuable resource. As such, significant efforts have been made to expand donation criteria at many centers. This constant pressure, coupled with the increasing effectiveness of antiviral therapies, has meant that more and more patients infected with hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) may be considered appropriate donors in the right circumstances...
2022: Hepatic Medicine: Evidence and Research
https://read.qxmd.com/read/35300491/viral-hepatitis-the-road-traveled-and-the-journey-remaining
#36
REVIEW
Ghulam Fareed Malik, Noval Zakaria, Muhammad Ibrahim Majeed, Faisal Wasim Ismail
Hepatitis is defined as inflammation of the liver and is commonly due to infection with The hepatotropic viruses - hepatitis A, B, C, D and E. Hepatitis carries one of the highest disease burdens globally and has caused significant morbidity and mortality among different patient populations. Clinical presentation varies from asymptomatic or acute flu-like illness to acute liver failure or chronic liver disease, characterized by jaundice, hepatomegaly and ascites among many other signs. Eventually, this can lead to fibrosis (cirrhosis) of the liver parenchyma and carries a risk of development into hepatocellular carcinoma...
2022: Hepatic Medicine: Evidence and Research
https://read.qxmd.com/read/35237077/evaluation-of-the-effect-of-hydromethanolic-seed-extract-of-lepidium-sativum-l-fetto-on-deep-fried-palm-oil-diet-induced-nonalcoholic-fatty-liver-disease-on-male-swiss-albino-mice
#37
JOURNAL ARTICLE
Ebsa Tofik Ahmed, Belay Zawdie, Suresh Kumar P Nair, Mengistu Welde, Tigist Mateos Husen
Introduction: Nonalcoholic fatty liver disease (NAFLD) is the most prevalent disease due to a dramatic change in dietary habits, especially an increase in consumption of fat and carbohydrates in deep-fried foods. Objective: The objective was to evaluate the effect of hydromethanolic seed extract of Lepidium sativum on deep-fried palm oil diet induced NAFLDon male mice. Methods: An experimental study design was conducted. Twenty-four male mice aged 8 to 10 weeks, weighing 32-42 g were divided into four groups...
2022: Hepatic Medicine: Evidence and Research
https://read.qxmd.com/read/35221734/minimally-invasive-surgery-for-intrahepatic-cholangiocarcinoma-patient-selection-and-special-considerations
#38
REVIEW
MacKenzie L Owen, Eliza W Beal
Intrahepatic cholangiocarcinoma (ICC) is an aggressive primary hepatic malignancy. Unfortunately, despite advancements in diagnosis, staging and management, mortality is high. Surgery remains the only curative treatment, but many patients present with advanced, unresectable disease. For patients able to undergo surgical resection, overall survival is improved, but remains low, with high rates of disease recurrence. Minimally invasive surgery (MIS), including laparoscopic and robotic approaches, are increasingly used in surgical resection for ICC...
2021: Hepatic Medicine: Evidence and Research
https://read.qxmd.com/read/35002337/reply-to-chemical-risk-factors-of-primary-liver-cancer-a-short-comment-response-to-letter
#39
COMMENT
Adam Barsouk, Krishna Chaitanya Thandra, Kalyan Saginala, Prashanth Rawla
No abstract text is available yet for this article.
2021: Hepatic Medicine: Evidence and Research
https://read.qxmd.com/read/34984034/erratum-the-prognostic-values-of-neutrophil-to-lymphocyte-ratio-and-platelet-to-lymphocyte-ratio-at-baseline-in-predicting-the-in-hospital-mortality-in-black-african-patients-with-advanced-hepatocellular-carcinoma-in-palliative-treatment-a-comparative-cohort
#40
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