journal
https://read.qxmd.com/read/31031834/nine-contemporary-therapeutic-directions-in-heart-failure
#21
REVIEW
Zaid Almarzooq, Manan Pareek, Lauren Sinnenberg, Muthiah Vaduganathan, Mandeep R Mehra
The global burden of heart failure has continued to increase dramatically with 26 million people affected and an estimated health expenditure of $31 billion worldwide. Several practice-influencing studies were reported recently, bringing advances along many frontiers in heart failure, particularly heart failure with reduced ejection fraction. In this article, we discuss nine distinct therapeutic areas that were significantly influenced by this scientific progress. These distinct areas include the emergence of sodium-glucose cotransporter-2 inhibitors, broadening the application of angiotensin-neprilysin inhibition, clinical considerations in therapy withdrawal in those patients with heart failure that 'recover' myocardial function, benefits of low-dose direct oral anticoagulants in sinus rhythm, targeted therapy for treating cardiac amyloidosis, usefulness of mitral valve repair in heart failure, the advent of newer left ventricular assist devices for advanced heart failure, the role of ablation in atrial fibrillation in heart failure, and finally the use of wearable defibrillators to address sudden death...
2019: Heart Asia
https://read.qxmd.com/read/31031833/the-safety-of-morphine-use-in-acute-coronary-syndrome-a-meta-analysis
#22
JOURNAL ARTICLE
Rugheed Ghadban, Tariq Enezate, Joshua Payne, Haytham Allaham, Ahmad Halawa, Hee Kong Fong, Obai Abdullah, Kul Aggarwal
Background: Morphine is widely used for pain control in patients with acute coronary syndrome (ACS). Several studies have questioned the safety of morphine in this setting with a concern of interaction with and reduced efficacy of antiplatelet agents. Objective: This study aims to systematically review the safety of morphine use in ACS. Methods: MEDLINE, EMBASE and the Cochrane Central Register of Controlled Trials were queried from inception through April 2018...
2019: Heart Asia
https://read.qxmd.com/read/31031832/knowledge-of-risk-factors-for-hypertension-in-a-rural-indian-population
#23
JOURNAL ARTICLE
Doreen Busingye, Simin Arabshahi, Roger G Evans, Michaela A Riddell, Velandai K Srikanth, Kamakshi Kartik, Kartik Kalyanram, Xuan Zhu, Oduru Suresh, George Howard, Amanda G Thrift
Objective: To study knowledge of risk factors and consequences of hypertension in a rural population in South India. Methods: This is a community-based study conducted among adults of a rural population in the Rishi Valley, India. Residents of randomised rural villages were invited to participate in a study of hypertension. We obtained measures of blood pressure, height, weight, waist and hip circumferences and questionnaire-based information on knowledge about hypertension, sociodemographic characteristics and health behaviours...
2019: Heart Asia
https://read.qxmd.com/read/31031831/mir-93-5p-is-a-novel-predictor-of-coronary-in-stent-restenosis
#24
JOURNAL ARTICLE
John F O'Sullivan, Antoinette Neylon, Eoin F Fahy, Pengyi Yang, Catherine McGorrian, Gavin J Blake
Aims: MicroRNAs (miRNAs), small non-coding RNAs, have been implicated as regulators of multiple phases of atherothrombosis, and some reports have suggested altered levels in coronary artery in-stent restenosis (ISR). We recently demonstrated that miR-93-5 p was able to discriminate between patients with stable coronary artery disease (CAD) and those with no CAD, after adjusting for traditional risk factors (RFs). Thus, we wanted to determine if circulating miRNAs could predict coronary ISR...
2019: Heart Asia
https://read.qxmd.com/read/31031830/managing-hypertension-in-2018-which-guideline-to-follow
#25
JOURNAL ARTICLE
Fabio Angeli, Gianpaolo Reboldi, Monica Trapasso, Adolfo Aita, Paolo Verdecchia
Hypertension is a global public health issue and a major cause of morbidity and mortality. Its prevalence is increasing in many Asian countries, with a number of countries with blood pressure above the global average. Although the average systolic blood pressure is decreasing worldwide since the 1980s at the rate of about 1 mm Hg systolic blood pressure per decade, it is increasing in low-income and middle-income countries, especially in the East and South Asian population. Of note, the much larger base Asian population results in a considerably larger absolute number of individuals affected...
2019: Heart Asia
https://read.qxmd.com/read/31031829/influence-of-type-and-duration-of-training-on-the-presence-of-an-abnormal-ecg-in-high-performance-athletes
#26
JOURNAL ARTICLE
Geoffrey Verrall, Angus Hains, Bronte Ayres, Richard Hillock
OBJECTIVE: To undertake an ECG in high level athletes to determine the morphology of the ECG and to assess the influences on the ECG of the amount of time in a high-performance programme and the type of sport played. DESIGN: Cross-sectional cohort study. SETTING: High-performance sports programme. INTERVENTIONS: Current symptoms (questionnaire) and length of time in a high-performance sports programme were recorded. Sports were classified as either high maximal oxygen uptake continuous, high maximal oxygen uptake repeated effort or static...
2019: Heart Asia
https://read.qxmd.com/read/31031828/antithrombotic-therapy-after-femoropopliteal-artery-stenting-12-month-results-from-japan-postmarketing-surveillance
#27
JOURNAL ARTICLE
Osami Kawarada, Michikazu Nakai, Kunihiro Nishimura, Hideki Miwa, Yusuke Iwasaki, Daitaro Kanno, Tatsuya Nakama, Yoshito Yamamoto, Nobuhiko Ogata, Masato Nakamura, Satoshi Yasuda
Objective: To investigate the effects of antithrombotic therapy on target lesion revascularisation (TLR) and major adverse cardiovascular and cerebrovascular events (MACCEs) at 12 months after femoropopliteal intervention with second-generation bare metal nitinol stents. Methods: A total of 277 lesions in 258 limbs of 248 patients with de novo atherosclerosis in the above-the-knee femoropopliteal segment were analysed from the Japan multicentre postmarketing surveillance...
2019: Heart Asia
https://read.qxmd.com/read/31031827/determinants-of-coronary-artery-disease-risk-factor-management-across-three-world-regions
#28
JOURNAL ARTICLE
Min Zhao, Ian Graham, Marie Therese Cooney, Diederick E Grobbee, Ilonca Vaartjes, Kerstin Klipstein-Grobusch
Background: The SUrvey of Risk Factors (SURF) indicated poor control of risk factors in subjects with established coronary heart disease (CHD). The present study aimed to investigate determinants of risk factor management in patients with CHD. Methods and results: SURF recruited 9987 consecutive patients with CHD from Europe, Asia and the Middle East between 2012 and 2013. Risk factor management was summarised as a Cardiovascular Health Index Score (CHIS) based on six risk factor targets (non-smoker/ex-smoker, body mass index <30, adequate exercise, controlled blood pressure, controlled low-density lipoprotein and controlled glucose)...
2019: Heart Asia
https://read.qxmd.com/read/31031826/prevalence-of-non-acute-ischaemic-cardiomyopathy-in-a-pakistani-cohort
#29
JOURNAL ARTICLE
Muhammad Salman Ghazni, Saba Aijaz, Rehan Malik, Asad Z Pathan
Heart failure with reduced left ventricular ejection fraction (HFrEF) is a frequently encountered clinical scenario. Coronary angiography (CAG) is usually performed to assess obstructive epicardial coronary artery disease (CAD) and the resultant ischaemia as causes of HFrEF. Objectives: To determine the frequency of obstructive CAD (OCAD) in patients with HFrEF and its independent predictors and outcomes. Methods: Retrospective observational study in Tabba Heart Institute on patients who underwent CAG during the past 4 years...
2019: Heart Asia
https://read.qxmd.com/read/30792824/global-cardiac-surgery-lessons-learnt-from-the-global-neurosurgery-movement
#30
JOURNAL ARTICLE
Dominique Vervoort, Kee B Park, JaBaris D Swain
No abstract text is available yet for this article.
2019: Heart Asia
https://read.qxmd.com/read/30728865/low-levels-of-ideal-cardiovascular-health-in-a-semi-urban-population-of-western-nepal-a-population-based-cross-sectional-study
#31
JOURNAL ARTICLE
Bishal Gyawali, Shiva Raj Mishra, Salim S Virani, Per Kallestrup
Background: The aim of this study was to assess the status of cardiovascular health among a semi-urban population of Nepal, and determine factors associated with ideal cardiovascular health. Methods: A population-based, cross-sectional study using a systematic random sample was conducted among 2310 adults aged ≥ 25 years in a semi-urban area of the Pokhara Metropolitan City previously named Lekthnath in Nepal. The ideal, intermediate and poor cardiovascular health were defined as the presence of 6-7, 4-5 or 1-3 health metrics, among a list of 7 health behaviours and healthfactors, namely smoking, body mass index, physical activity, fruits and vegetables intakes, harmful alcohol consumption, blood pressure, and fasting blood glucose...
2019: Heart Asia
https://read.qxmd.com/read/30728864/secondary-prevention-therapies-in-acute-coronary-syndrome-and-relation-to-outcomes-observational-study
#32
JOURNAL ARTICLE
Clara K Chow, David Brieger, Mark Ryan, Nadarajah Kangaharan, Karice K Hyun, Tom Briffa
Objective: To ascertain the use of secondary prevention medications and cardiac rehabilitation after an acute coronary syndrome (ACS) and the impact on 2-year outcomes. Methods: CONCORDANCE (Cooperative National Registry of Acute Coronary care, Guideline Adherence and Clinical Events) is a prospective, observational registry of 41 Australian hospitals. A representative sample of 6859 patients with an ACS and 6 months' follow-up on 31 May 2016 were included. The main outcome measure was use of ≥75% of indicated medications (≥4/5 (or ≥3/4 if contraindicated) of angiotensin-converting enzyme (ACE) inhibitor/angiotensin receptor blocker, beta-blocker, lipid-lowering therapy, aspirin and other antiplatelet)...
2019: Heart Asia
https://read.qxmd.com/read/30728863/impact-of-congenital-cardiac-catheterization-project-on-outcomes-quality-improvement-c3po-qi-in-lmics
#33
JOURNAL ARTICLE
Fatima Ali, Mohammad Qasim Mehdi, Saleem Akhtar, Nadeem Aslam, Rashid Abbas, Izat Shah, Jabbir Abidi, Sajid Arthur, Zeenat Nizar, Andrea Goodmann, Lisa Bergersen, Babar Hasan
Background: The importance of registries for collaborative quality improvement has been overlooked in low/middle-income countries (LMIC). Aga Khan University Hospital (AKUH) in Pakistan joined the Congenital Cardiac Catheterization Project on Outcomes-Quality Improvement (C3PO-QI) in March 2017 with the goal of leveraging international collaboration to improve patient care and institutional standards. Methods: The C3PO-QI key driver-based approach was used, with certain modifications, for process re-engineering in AKUH's congenital cardiac catheterisation laboratory (CCL) to reduce radiation exposure during cardiac catheterisation procedures (the primary outcome of C3PO- QI)...
2019: Heart Asia
https://read.qxmd.com/read/30728862/novel-technique-to-manage-pacemaker-exposure-with-buried-flap-reconstruction-case-series%C3%AF
#34
JOURNAL ARTICLE
Raja Tiwari, Shruti Marwah, Ambuj Roy, Maneesh Singhal
Objective: Exposure of implantable electrical devices may increase morbidity and mortality significantly. Usually superficial infections are conservatively managed whereas invasive infections necessitate complete capsulectomy, sub-pectoral placement or implant exchange. Most commonly inadequate soft tissue coverage, soft tissue thinning and scar dehiscence over the edge of the pacemaker are the primary predisposing event. Multiple local surgical options have been described, however, with all these designs, the final scar still remains over the edge of the pacemaker and continue to have a tendency of thinning out with time...
2019: Heart Asia
https://read.qxmd.com/read/30556816/reuse-of-catheters-and-devices-labelled-for-single-use-evidence-recommendations-and-oversight
#35
EDITORIAL
Thomas C Crawford, Kim A Eagle
No abstract text is available yet for this article.
2018: Heart Asia
https://read.qxmd.com/read/30556542/single-use-medical-devices-economic-issues
#36
JOURNAL ARTICLE
Philip Jacobs, Ilke Akpinar
No abstract text is available yet for this article.
2018: Heart Asia
https://read.qxmd.com/read/30555537/electrophysiological-properties-of-the-south-asian-heart
#37
JOURNAL ARTICLE
James O Neill, Muzahir Hassan Tayebjee
Objective: The South Asian population has a lower burden of arrhythmia compared with Caucasians despite a higher prevalence of traditional cardiovascular risk factors. We aimed to determine whether this was due to differences in the electrophysiological properties of the South Asian heart. Methods: We performed a retrospective cohort study of South Asian and Caucasian patients who underwent an electrophysiology study for supraventricular tachycardia between 2005 and 2017...
2018: Heart Asia
https://read.qxmd.com/read/30555536/optimal-duration-and-predictors-of-diagnostic-utility-of-patient-activated-ambulatory-ecg-monitoring
#38
JOURNAL ARTICLE
Eugene S J Tan, Swee-Chong Seow, Pipin Kojodjojo, Devinder Singh, Wee Tiong Yeo, Toon Wei Lim
Objective: We studied the optimal duration of ambulatory event monitors for symptomatic patients and the predictors of detected events. Methods: Patients with palpitations or dizziness received a patient-activated handheld event monitor which records 30 s single-lead ECG strips. Patients were monitored in an ambulatory setting for a range of 1-4 weeks and ECG strips interpreted by five independent electrophysiologists. Event pick-up rates and clinical covariates were analysed...
2018: Heart Asia
https://read.qxmd.com/read/30402141/cancer-antigen-125-and-outcomes-in-acute-heart-failure-a-systematic-review-and-meta-analysis
#39
JOURNAL ARTICLE
Ka Hou Christien Li, Mengqi Gong, Guangping Li, Adrian Baranchuk, Tong Liu, Martin C S Wong, Aaron Jesuthasan, Rachel W C Lai, Jenny Chi Ling Lai, Alex Pui Wai Lee, Antoni Bayés-Genis, Rafael de la Espriella, Juan Sanchis, William K K Wu, Gary Tse, Julio Nuñez
Background: Carbohydrate antigen-125 (CA125) is an ovarian cancer marker, but recent work has examined its role in risk stratification in heart failure. A recent meta-analysis examined its prognostic value in heart failure generally. However, there has been no systematic evaluation of its role specifically in acute heart failure (AHF). Methods: PubMed and EMBASE databases were searched until 11 May 2018 for studies that evaluated the prognostic value of CA125 in AHF...
2018: Heart Asia
https://read.qxmd.com/read/30397415/preoperative-cigarette-smoking-and-short-term-morbidity-and-mortality-after-cardiac-surgery-a-meta-analysis
#40
JOURNAL ARTICLE
Nicholas Gregory Ross Bayfield, Adrian Pannekoek, David Hao Tian
Currently, the choice of whether or not to electively operate on current smokers is varied among cardiothoracic surgeons. This meta-analysis aims to determine whether preoperative current versus ex-smoking status is related to short-term postoperative morbidity and mortality in cardiac surgical patients. Systematic literature searches of the PubMed, MEDLINE and Cochrane databases were carried out to identify all studies in cardiac surgery that investigated the relationship between smoking status and postoperative outcomes...
2018: Heart Asia
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