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Journals Journal of Neonatal-perinatal ...

Journal of Neonatal-perinatal Medicine

https://read.qxmd.com/read/38143377/three-or-four-doses-of-intravenous-immunoglobulin-g-treatment-for-isoimmune-hemolytic-disease-a-case-series-and-literature-review
#21
JOURNAL ARTICLE
Y Zheng, Y Almeyda-Alejo, D Tumin, N S J Redpath, J Guillen-Hernandez
BACKGROUND: Neonates affected by isoimmune hemolytic disease (HDN) are at risk of developing severe hyperbilirubinemia. Studies show that increasing levels of bilirubin impact neonatal neurodevelopment. To avoid complications associated with exchange transfusion, intravenous immunoglobulin G (IVIG) is used to treat hyperbilirubinemia. We included all infants who received more than two doses of IVIG treatment for isoimmune hemolytic disease. We analyzed the incidence of side effects associated with IVIG treatment and the rate of exchange transfusion...
December 20, 2023: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38073400/hypothermia-on-admission-and-its-association-with-neonatal-mortality-and-morbidity-in-neonatal-intensive-care-unit
#22
JOURNAL ARTICLE
M A Mostafa, O M AbdelHaie, S A Abdelmegiud, B K M Lasheen, R M Zakaria
BACKGROUND: Neonatal hypothermia is a drop in the newborn's core temperature less than 36.5°C. It is crucial in neonatal morbidity and mortality, particularly in preterm infants. This research aimed to assess the incidence and risk factors of neonatal hypothermia and its effect on neonatal mortality and short-term morbidity during Neonatal Intensive Care Unit (NICU) admission. METHODS: This observational study was conducted on all neonates admitted to the NICU at Benha University Hospital...
December 8, 2023: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38073401/a-rare-case-of-hepatic-sinusoidal-occlusive-syndrome-in-a-premature-neonate-with-trisomy-21
#23
JOURNAL ARTICLE
A J Alenchery, N K Yeaney, C B Chen, R Talati, E Vogelius, C Tan, K Radhakrishnan
Trisomy 21 (Down Syndrome) may lead to multiple hematological and hepatobiliary manifestations including the development of transient abnormal myelopoiesis. While many cases resolve, transient abnormal myelopoiesis may lead to significant morbidity and mortality in a small percentage of patients. This condition may present a diagnostic challenge for physicians and currently there is only limited data on effective treatments, particularly with low blast percent transient abnormal myelopoiesis. We present a case of a neonate with trisomy 21 and multiple congenital anomalies who consequently developed hepatic failure with evidence of non-cirrhotic portal hypertension likely due to transient abnormal myelopoiesis...
December 7, 2023: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38073399/the-influence-of-late-prematurity-on-the-encephalopathy-exam-of-infants-with-neonatal-encephalopathy
#24
JOURNAL ARTICLE
A Kodidhi, M Riley, Z Vesoulis
BACKGROUND: Late preterm (LPT) infants are increasingly treated for hypoxic-ischemic encephalopathy (HIE). However, neurodevelopmental differences of LPT infants may independently influence the neurologic exam and confound care. METHODS: Perinatal and outcome characteristics were extracted along with the worst autonomic and state/neuromuscular/reflex Sarnat components in a cross-section of infants with moderate/severe HIE. Infants were classified as late preterm (LPT, 34-36 weeks) or term (>36 weeks)...
December 7, 2023: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38073398/identifying-neonatal-intensive-care-nicu-admissions-using-administrative-claims-data
#25
JOURNAL ARTICLE
A J Vance, S Bell, A Tilea, D Beck, K M Tabb, K Zivin
BACKGROUND: To define a method for identifying neonatal intensive care unit (NICU) admissions using administrative claims data. METHODS: This was a retrospective cohort study using claims from Optum's de-identified Clinformatics ® Data Mart Database (CDM) from 2016 -2020. We developed a definition to identify NICU admissions using a list of codes from the International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM), Current Procedural Terminology (CPT), and revenue codes frequently associated with NICU admissions...
December 7, 2023: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38043027/postpartum-care-discussions-and-counseling-for-the-peripartum-period
#26
JOURNAL ARTICLE
A Prince, J Wade, M L Power, N Gunawansa, A Cruz-Bendezú, J Schulkin, C J Macri
BACKGROUND: Traditionally, postpartum care is confined to inpatient care immediately post birth and one appointment approximately six weeks postpartum. Data supports a continuum of care model as best for the health of mother and baby. Despite most women having significant concerns about the postpartum period, these concerns are frequently incompletely addressed by providers. We surveyed prenatal and postpartum patients to understand their concerns and experiences discussing postpartum care with providers...
December 1, 2023: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38043023/prognostic-dilemmas-for-sids-in-idiopathic-fetal-right-atrium-dilatation-case-report-and-review-literature
#27
JOURNAL ARTICLE
M Stabile, L M A Cipullo, S Carlucci, A F Rispoli, G Stabile
The authors describe a case of fetal isolated right atrial enlargement or IDRA (idiopathic dilatations of the right atrium) evident in third trimester, complicated by arrhythmia in the female infant during the 1° month of life with ECG diagnosis of Wolf-Parkinson-White syndrome (WPW). The eldest sister died at 6 years because of an arrhythmia with the same diagnosis of WPW. The review of the literature on IDRA frequently shows a familial genetic aggregation. The pathogenetic mechanism underlying the dilation of the right atrium could consist of a myopathy or electrical conduction disorder...
December 1, 2023: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38043022/multiple-vascular-malformations-in-a-newborn
#28
JOURNAL ARTICLE
P Krcho, J Derco, M Juhas, S M Donn
We describe the case of a term newborn who presented with congenital testicular torsion at 10 hours of age. During the evaluation of this problem, additional malformations were encountered. Diagnostic and therapeutic considerations are addressed.
December 1, 2023: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38043021/the-possible-role-of-artificial-intelligence-in-deciding-postnatal-steroid-management-in-extremely-premature-ventilated-infants
#29
JOURNAL ARTICLE
A Bottu, S Manzar
Clinical decision support (CDS) has shown a positive effect on physicians. There is variability among physicians about using postnatal steroids (PNS) in preterm (PT) infants. It is, therefore, essential to develop tools supporting the decision to use PNS in PT infants. We propose a model using online tools such as CDS in deciding to use PNS in PT infants. We combined the online bronchopulmonary dysplasia (BPD) estimator and extubation success calculator tools to be used as a simple bedside tool assisting decisions about using PNS in ventilated PT infants...
December 1, 2023: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38043020/noise-survey-of-neonatal-intensive-care-unit-at-a-government-tertiary-care-centre
#30
JOURNAL ARTICLE
P Lokwani, N Gupta, S K Choudhary, A K Singh
BACKGROUND: With technological advancement, Neonatal Intensive Care Units (NICU) have become noisier than ever. Studies have shown the detrimental effects of increasing noise in NICU on growing pre-term and sick neonates. The present study aimed to survey the amount of noise in one of the NICU blocks of a government tertiary care centre and explore ways to control it when dealing with these sick babies. METHODS: A detailed noise survey was carried out, for February 2023, in one of the two blocks of NICU in a government tertiary-care centre...
November 29, 2023: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38007677/clinical-determinants-of-intestinal-failure-and-death-in-preterm-infants-with-surgical-necrotizing-enterocolitis
#31
JOURNAL ARTICLE
P M Garg, M X Denton, R Talluri, M A Y Ansari, R Riddick, M M Ostrander, A G McDonald, M H Premkumar, W B Hillegass, P P Garg
OBJECTIVE: We sought to investigate the clinical determinants of intestinal failure and death in preterm infants with surgical NEC. METHODS: Retrospective comparison of clinical information between Group A = intestinal failure (Parenteral nutrition (PN) >90 days) and death and Group B = survivors and with PN dependence <  90 days in preterm infants with surgical NEC. RESULTS: Group A (n = 99/143) had a lower mean gestational age (26...
November 22, 2023: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38007676/delayed-cord-clamping-versus-cord-milking-in-vigorous-neonates-%C3%A2-35-weeks-gestation-born-via-cesarean-a-randomized-clinical-trial
#32
JOURNAL ARTICLE
Mithuna Murali, Giridhar Sethuraman, Jaishree Vasudevan, L Umadevi, Usha Devi
BACKGROUND: Delayed cord clamping (DCC) is the recommended strategy in neonates not requiring resuscitation, but umbilical cord milking (UCM) can also be used in term babies. DCC has been found to offer advantages more than just placental transfusion. OBJECTIVE: To compare the neonatal outcomes of DCC and UCM at birth in vigorous neonates ≥35 weeks born via cesarean section. METHODS: We included all vigorous neonates born ≥35 weeks of gestation through the cesarean section in this open-label randomized controlled trial...
November 22, 2023: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38007675/improving-maternal-update-rates-within-the-first-hour-of-nicu-admission
#33
JOURNAL ARTICLE
S Manzar, S R Cole, R Bhat
BACKGROUND: Timely communication is essential in attaining maternal satisfaction, developing an excellent physician-patient rapport, and increasing trust. This study reports a significant improvement in maternal communication rates through the quality improvement method. METHODS: An educational module was developed, and NICU staff was presented with the slides, followed by a performance questionnaire to demonstrate understanding. The first phase was completed by obtaining feedback from mothers through a questionnaire...
November 22, 2023: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/37742666/safety-evaluation-of-the-use-of-calcineurin-inhibitor-to-prenatal-and-postpartum-women-in-japan-from-a-health-administrative-database
#34
JOURNAL ARTICLE
K Yashima, A Noda, T Ishikawa, F Matsuzaki, K Miyakoda, H Nishigori, N Mano, T Obara
BACKGROUND: To investigate the use of calcineurin inhibitors (CNIs) in pregnant Japanese women and to evaluate their safety in infants. METHODS: Data were extracted from the claims database of the Japan Medical Data Center. The prevalence of CNIs was evaluated 180 days before pregnancy onset, during pregnancy, and at 180-day postpartum. We investigated the characteristics of the infants, including the presence of major malformations and their diagnoses, for 1 year after birth...
September 22, 2023: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/37742664/clinical-impact-of-analgesic-sedative-agents-and-peri-operative-clinical-status-on-white-matter-brain-injury-in-preterm-infants-following-surgical-nec
#35
JOURNAL ARTICLE
P M Garg, A Rebentisch, M Zhang, J Ware, M Pippins, C Taylor, K Reddy, T Lewis, T E Inder, W B Hillegass
BACKGROUND: The potential influence of exposure to analgesic-sedative agents (ASA) before, during, and after surgical NEC and peri-operative clinical status on white matter injury (WMI) in preterm infants has not been fully defined, and a comprehensive evaluation may inform future research and clinical interventions. METHODS: A retrospective study comparing ASA exposure before/during /after surgical NEC and peri-operative clinical status in neonates with and without WMI...
September 16, 2023: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/37718865/noninvasive-high-frequency-oscillatory-ventilation-versus-noninvasive-positive-pressure-ventilation-in-preterm-neonates-after-extubation-a-randomized-controlled-trial
#36
JOURNAL ARTICLE
W O Ahmed, I S H AbuSaif, S A Salaheldin, H E Hashem, O A Obaid, A A Obaid, S M AbdElrazik, M E Ibrahim, D M Shinkar
BACKGROUND: Weaning from mechanical ventilation is a challenging phase of neonatal respiratory support [1]. Choosing efficient and safe noninvasive modality to prevent re-intubation and choosing the optimal time for weaning are key points for weaning success. The aim of the study is to compare the efficiency and safety of noninvasive high frequency oscillatory ventilation (NHFOV) versus noninvasive positive pressure ventilation (NIPPV) as respiratory support after extubation in preterms with respiratory distress syndrome (RDS)...
September 15, 2023: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/37718856/clinical-and-neurodevelopmental-outcomes-in-premature-infants-exposed-to-intravenous-fish-and-soybean-oil-based-lipid-emulsions
#37
JOURNAL ARTICLE
D G A Guerra, L A Winter, A G Moreira, A K Gong, T L Johnson-Pais, C L Blanco
BACKGROUND: The optimal composition of lipid emulsions in parenteral nutrition (PN) for premature infants remains controversial. This study examined the effects of a combination of soybean oil-based (SoyLE) and fish oil-based (FishLE) lipid emulsions compared to FishLE as monotherapy on the lipid and fatty acid profiles and clinical outcomes of premature infants requiring prolonged PN. METHODS: 42 premature infants received FishLE+SoyLE or FishLE. Serum concentrations of lipoproteins and 29 fatty acids (FA) were measured at baseline, 4, and 8 weeks of PN and growth and neurodevelopmental outcomes were measured at 3, 6, 12, 18, and 24 months of life...
September 15, 2023: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/37718874/accidental-lipid-overdose-in-a-preterm-infant-a-case-report
#38
JOURNAL ARTICLE
M S Ryan, J McIntyre, L D Bramwell, S Ojha
BACKGROUND: Intravenous lipid emulsions (ILEs) provide essential fatty acids during parenteral nutrition (PN). Serious adverse events including death can occur from overdose. We report an accidental overdose in a preterm infant. METHOD: On Day 2 of life, a 29-week gestational age (GA) twin was accidentally given 47.5 mL of Intralipid20% (≈3x daily amount) in 50-minutes. RESULTS: No apparent clinical deterioration occurred, although blood samples were lipemic...
September 14, 2023: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/37718873/congenital-neuroblastoma-presenting-as-profound-neonatal-metabolic-acidosis-with-systemic-hypertension-case-report
#39
JOURNAL ARTICLE
H F Morris, S Sran
BACKGROUND: Clinical collapse in the newborn most often occurs secondary to sepsis, delivery complications, congenital cardiac defects, or inborn errors of metabolism. We report on a neonate with respiratory, cardiac, and hepatic failure, with disproportionate metabolic acidosis and systemic hypertension, found to be caused by a congenital neuroblastoma. CASE DESCRIPTION: A term infant presented to our Level IV NICU via emergent transport at 12 hours of life with clinical and laboratory findings consistent with respiratory, cardiac, and hepatic failure...
September 14, 2023: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/37718872/effects-of-iron-supplementation-to-iron-depleted-and-iron-replete-pregnant-danish-women-defining-criteria-for-identification-of-women-who-can-manage-without-supplements-a-randomized-placebo-controlled-study
#40
JOURNAL ARTICLE
N T Milman
OBJECTIVE: To define criteria based on iron status parameters for the identification of healthy women who do need/do not need iron supplementation during normal pregnancy. METHODS: Randomized, double-blind, placebo-controlled study of 113 women (62 iron-, 51 placebo treated) and their newborns. Iron dose was 66 mg elemental iron as ferrous fumarate daily from 14-18 weeks gestation to delivery. Hemoglobin (Hb), serum (S)-ferritin, S-transferrin saturation percentage, and S-erythropoietin were measured during gestation, prepartum, one week and 8 weeks postpartum...
September 14, 2023: Journal of Neonatal-perinatal Medicine
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