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Journals Journal of Neonatal-perinatal ...

Journal of Neonatal-perinatal Medicine

https://read.qxmd.com/read/38607768/congenital-fibrous-fusion-of-the-jaws-synechiae-with-cleft-palate-a-case-report
#1
JOURNAL ARTICLE
W Alhussin, S Susnerwala
BACKGROUND: Congenital maxillomandibular fusion is a rare disorder. Maxillomandibular fusion is usually discovered immediately after birth because the newborn is unable to open mouth or feed normally. The fusion defects can present with a wide range of severity, ranging from mucosal band (synechiae) to complete bony fusion (syngnathia). CASE DESCRIPTION: We report a case of congenital alveolar synechiae with posterior cleft palate in a 3-day-old male neonate. The newborn was managed with the help of a multi-disciplinary approach...
April 8, 2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38607766/association-of-hypermagnesemia-at-birth-and-admission-hypothermia-in-pre-term-infants-a-secondary-analysis-of-a-prospective-cohort-study
#2
JOURNAL ARTICLE
J P de Siqueira Caldas, E de Almeida Orro Junqueira, J Fernandes de Camargo, S T M Marba
BACKGROUND: Hypothermia on admission is associated with increased mortality in preterm infants. Drugs administered to pregnant women is implicated in its occurrence. Since magnesium sulfate has a myorelaxant effect, we aimed evaluating the association of hypermagnesemia at birth and admission hypothermia (axillary temperature <36.5°C) in preterm infants. METHODS: We performed a secondary analysis of a prospective cohort study database including inborn infants <34 weeks, without congenital malformations...
April 8, 2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38607769/influence-of-umbilical-cord-clamping-time-on-cerebral-oxygenation-and-early-cardiac-function-in-term-infants
#3
JOURNAL ARTICLE
M Satar, A H Erol, M Özdemir, N Özbarlas, A Atmış, F Özlü, S Büyükkurt
BACKGROUND: Delayed cord clamping is the standard of care for both term and preterm infants worldwide. The aim of this study was to evaluate the effect of 60-second or 180-second delayed cord clamping during labor on cerebral oxygenation and cardiac function. METHODS: Healthy newborns were divided into two groups: a 60-second delay in cord clamping (60-s DCC) and a 180-second delay in cord clamping (180-s DCC) at birth. Pulse oximetry and cerebral near-infrared spectroscopy (cNIRS) probes were placed during postnatal care...
April 6, 2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38607767/evaluation-of-systemic-inflammatory-indices-in-the-diagnosis-of-early-onset-neonatal-sepsis-in-very-low-birth-weight-infants
#4
JOURNAL ARTICLE
U Cakir, C Tayman
BACKGROUND: Previously, not six systemic inflammatory indices were evaluated in the diagnosis of early onset sepsis (EOS) in very low birth weight (VLBW, <1500g) premature infants. OBJECTIVES: We evaluated the effectiveness of systemic inflammatory indices in the diagnosis of EOS in VLBW infants. METHODS: Premature infants with birth weight <1500 g were included in the study. Six systemic inflammatory indices including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), systemic immune-inflammation index (SII), pan-immune-inflammation value (PIV), and systemic inflammation response index (SIRI) were compared in patients with EOS (treatment group) and without EOS (control group)...
April 6, 2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38578905/heart-rate-and-oxygen-saturation-patterns-in-very-low-birth-weight-infants-with-early-onset-sepsis-and-histologic-chorioamnionitis
#5
JOURNAL ARTICLE
Charlene R Bultmann, Jiaxang Qiu, Briana Belmonte, Karen D Fairchild, Brynne A Sullivan
BACKGROUND: Chorioamnionitis and early onset sepsis (EOS) in very low birth weight (VLBW,< 1500 g) infants may cause a systemic inflammatory response reflected in patterns of heart rate (HR) and oxygenation measured by pulse oximetry (SpO2). Identification of these patterns might inform decisions about duration of antibiotic therapy after birth. OBJECTIVE: Compare early HR and SpO2 patterns in VLBW infants with or without early onset sepsis (EOS) or histologic chorioamnionitis (HC)...
April 2, 2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38457156/a-quality-improvement-strategy-to-reduce-unintended-extubation-in-the-very-low-birth-weight-infant-a-case-report
#6
JOURNAL ARTICLE
N Chahin, M S Yitayew, L Shaver, J L Reed, M Ridore, J Santoro, R R Moores, L Soghier, B Short, K D Hendricks-Muñoz
BACKGROUND: Unintended extubations remain a common complication across neonatal intensive care units, with very low birthweight infants being the most vulnerable of them all. Ongoing efforts across different institutions exist with the goal of reducing the rate of unintended extubations to keep a median rate of <2 events per 100 ventilator days as defined by the Vermont Oxford Network. Our objective was to reduce unintended extubations in the very low birthweight infant in a large delivery hospital to ≤2/100 ventilator days...
March 5, 2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38427505/hyperbilirubinemia-screening-and-treatment-in-neonates-born-prior-to-35-weeks-of-gestation
#7
JOURNAL ARTICLE
S Khan, H Coo, F Khurshid
BACKGROUND: Guidelines on when to screen for neonatal hyperbilirubinemia apply to infants born at 35 weeks or later of gestation. It is unknown whether infants born earlier would benefit from similar guidelines. Our objective was to examine hyperbilirubinemia screening and phototherapy prescription among early preterm infants during the first 6 days of life. METHODS: We reviewed the charts of 193 infants born prior to 35 weeks of gestation who were admitted to a tertiary care NICU in Southeastern Ontario in 2018-2019...
February 24, 2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38393924/oral-feeding-trajectories-and-neurodevelopmental-outcomes-at-12-and-24%C3%A2-month-follow-up-for-preterm-infants
#8
JOURNAL ARTICLE
L J Dietrich, A Gong, J Gelfond, C L Blanco
BACKGROUND: Few studies characterize feeding performance in the NICU when predicting neurodevelopmental outcomes. Our objective was to investigate the relationship between time to full oral feeds (FULL-PO) and neurodevelopmental and feeding outcomes in the first 2 years in preterm infants admitted to the NICU. METHODS: This retrospective study included infants born between 01/01/2014-07/31/2017, gestational age <  32 weeks and/or birth weight <  1500 g...
February 23, 2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38393923/trial-of-labor-after-cesarean-maternal-and-neonatal-outcomes-from-the-consortium-on-safe-labor
#9
JOURNAL ARTICLE
J M Phillips, D Polyakov, R L Amdur, H K Ahmadzia
BACKGROUND: The aim of our study is to describe maternal and neonatal morbidity and mortality in patients undergoing trial of labor after cesarean from the Consortium on Safe Labor. METHODS: This was a secondary analysis of the Consortium on Safe Labor database, a retrospective cohort study over a 7 year study period. Maternal and neonatal outcomes were evaluated based on desired delivery mode: planned elective repeat cesarean delivery or trial of labor after cesarean...
February 23, 2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38277305/external-biliary-drainage-before-choledochal-cyst-treatment-in-a-very-low-birth-weight-infant
#10
JOURNAL ARTICLE
T Lee, C-W Chen
Choledochal cysts (CC) are congenital biliary tract dilatations. Infantile CC (IFCC) in very low birth weight (VLBW) infants is rare. This is a case of a huge IFCC presented in VLBW preterm infant managed with external biliary drainage prior to definitive treatment. Electrolyte imbalance, poor weight gain, and infections were managed during external biliary drainage maintenance. Choledochal cyst excision and Roux-en-Y hepaticoenterostomy were successfully performed when the infant weighed 4.9 kg 5 months later...
January 24, 2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38277306/risk-of-orofacial-clefts-in-relation-to-maternal-body-mass-index-diabetes-and-hypertension
#11
JOURNAL ARTICLE
A M Da Silva, J R De Lavôr, V S Freitas, A R Vieira
BACKGROUND: To investigate if maternal body mass index, diabetes and hypertension are associated with orofacial clefts. METHODS: Case-control study. Information from 53,188 live births with and without orofacial cleft registered at USA Vital Statistics Natality Birth Data between 2017 and 2021. Case group consisted of all affected live births diagnosed with orofacial clefts (13,297 cases). Comparison group consisted of 39,891 live births without clefts or any other congenital malformation...
January 20, 2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38251067/twins-with-alveolar-capillary-dysplasia-with-misalignment-of-pulmonary-veins-strategies-for-diagnosis-and-management
#12
JOURNAL ARTICLE
S Brady, U Krishnan, A Saqi, D Vargas
We present a case of dichorionic-diamniotic twin females who developed hypoxemic respiratory failure. They were ultimately diagnosed by lung biopsy with alveolar capillary dysplasia with misalignment of pulmonary veins. This case highlights a practical approach to reaching a diagnosis in infants with suspected developmental lung disease.
January 16, 2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38251066/the-effects-of-gestational-age-on-neonatal-cholestasis-a-retrospective-cohort-study
#13
JOURNAL ARTICLE
N El Raichani, M Thibault, F Alvarez, J-C Lavoie, I Mohamed
BACKGROUND: Reference guidelines for neonatal conjugated hyperbilirubinemia (cholestasis) management use a uniform approach regardless of gestational age (GA). We hypothesize that the clinical pattern of neonatal cholestasis is tightly related to GA. The aim of this study was to describe the effects of GA on neonatal cholestasis. METHODS: A retrospective 4-year cohort study in a 70-beds neonatal care unit. Neonates with conjugated bilirubin≥34.2μmol/L (2 mg/dL) were identified...
January 13, 2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38217617/rapid-cycle-deliberate-practice-improves-resident-performance-during-elbw-resuscitation
#14
JOURNAL ARTICLE
B R Hadfield, T Sawyer, A G Moreira, R Farner, M M Vasquez
BACKGROUND: Neonatal Resuscitation is a required competency for pediatric and family medicine residency programs. Simulation-based training can be used to supplement clinical experience. Rapid Cycle Deliberate Practice (RCDP) has been validated as an effective education model and is gaining favor over traditional simulation models. The aim of this study was to evaluate the effectiveness of a simulation-based rapid cycle deliberate practice (RCDP) intervention on extremely low birth weight (ELBW) infant resuscitation...
January 12, 2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38217616/risk-factors-for-postoperative-complications-in-preterm-infants-with-surgical-necrotizing-enterocolitis-and-associated-outcomes
#15
JOURNAL ARTICLE
P P Garg, R Riddick, M A Y Ansari, I Pittman, M R Ladd, P Porcelli, P M Garg
BACKGROUND: We aim to determine clinical risk factors for postoperative complications in preterm infants with surgical necrotizing enterocolitis (NEC) or spontaneous intestinal perforation (SIP). METHODS: A retrospective cohort study of preterm infants with surgical NEC or SIP to compare clinical factors between those with and without postoperative complications. RESULTS: 78/109 (71.5%) infants had any complication following surgical NEC. Adhesions (20/35, 57...
January 8, 2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38217615/the-hero-score-enhancing-prognosis-and-predicting-nosocomial-infections-in-newborns-insights-from-the-neonatal-intensive-care-unit
#16
JOURNAL ARTICLE
Fatiha Bennaoui, Abdessamad Lalaoui, Nadia El Idrissi Slitine, Nabila Soraa, Fadl Mrabih Rabou Maoulainine
BACKGROUND: Nosocomial infections pose a significant health risk to neonates, and traditional biomarkers used for diagnosis often fall short in predicting such infections. In this study, we evaluate the efficacy of the HeRO (Heart Rate Observation score), a novel predictive tool for late-onset neonatal sepsis, in improving neonatal prognosis and reducing morbidity and mortality rates. METHODS: A prospective study was conducted from September 2020 to May 2021, reviewing patient evaluation for all neonates admitted to the neonatal intensive care unit during this period after the implementation of the HeRO score...
January 6, 2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38217614/fetal-circular-shunt-in-ebstein-s-anomaly-and-non-steroidal-anti-inflammatory-treatment
#17
JOURNAL ARTICLE
F L Peña, T W Emanuelson, S H Todman, R C Jones, S Mahajan
A circular shunt is a poor prognostic factor associated with Ebstein's anomaly. Targeting the constriction of the ductus arteriosus (DA) in order to limit or resolve the circular shunt, has been shown to improve fetal outcomes. Prenatal non-steroidal anti-inflammatory drugs (NSAIDs) have been known to constrict the DA. Recently, prenatal NSAIDs have been used for that purpose in the treatment of circular shunt. Limited research shows that it may be an effective treatment leading to improved fetal outcomes. In this article, we did an extensive review of literature to describe this therapy's effectiveness and outcomes...
January 6, 2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38189715/congenital-diaphragmatic-hernia-with-associated-broncho-pulmonary-sequestration-a-report-of-two-cases-and-a-literature-review
#18
JOURNAL ARTICLE
Moath Alhamad, Dhullipala Anand
BACKGROUND: Congenital Diaphragmatic Hernia (CDH) is a severe congenital anomaly with significant morbidity and mortality. It can be isolated or can be associated with other congenital anomalies, including broncho-pulmonary sequestration (BPS). The association of CDH with BPS (CDH+BPS) is uncommon but has been previously reported, and it can complicate the course of the disease in patients with CDH. We report two cases of CDH+BPS that were recently treated at our CDH-Qatar (CDH-Q) program...
January 5, 2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38189716/the-association-of-cumulative-vasoactive-drugs-and-neurodevelopmental-outcomes-in-preterm-infants-29-weeks-gestation
#19
JOURNAL ARTICLE
R Amer, C DeCabo, M Elnagary, M M Seshia, Y N Elsayed
OBJECTIVE: To assess the effect of cardiovascular medications on the neurodevelopment of preterm infants, as measured by calculated cumulative time of vasoactive-inotropic score (VISct). METHODS: A retrospective study was conducted on preterm infants who developed significant hypotension defined as a mean BP more than 2SDs below the mean for GA and received treatment with duration >  6 hours for each hypotensive episode, we calculated the vasoactive inotropic score (VIS) and cumulative exposure to cardiovascular medications over time (VISct)...
January 4, 2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38189714/periventricular-hemorrhagic-infarction-in-preterm-neonates-etiology-and-time-of-development
#20
JOURNAL ARTICLE
N Ilves, T Metsvaht, R Laugesaar, K Rull, M Lintrop, M Laan, D Loorits, P Kool, P Ilves
BACKGROUND: To find the obstetrical and delivery associated risk factors of antenatal and postnatal grade III intraventricular hemorrhage (IVH) or periventricular hemorrhagic infarction (PVHI) in preterm neonates. METHODS: A retrospective study of obstetric and delivery associated risk factors included neonates (<35 gestational weeks) with severe IVH/PVHI (n = 120) and a prospectively collected control group (n = 50). The children were divided into: (1) antenatal onset group (n = 27) with insult visible on cerebral ultrasonography within the first 12 hours of birth or periventricular cystic changes visible in PVHI within the first 3 days; (2) neonatal onset group (n = 70) with insult diagnosed after initial normal findings or I-II grade IVH, and (3) unknown time-onset group (n = 23) with insult visible at >  12 h of age...
January 4, 2024: Journal of Neonatal-perinatal Medicine
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