Elle C Moore, Gerard C Blobe, Nicholas C DeVito, Brent A Hanks, Michael R Harrison, Christopher J Hoimes, Jingquan Jia, Michael A Morse, Parvathy Jayaprakasan, Andrew MacKelfresh, Hillary Mulder, Adam J Hockenberry, Alia Zander, Martin C Stumpe, Jackson Michuda, Kyle A Beauchamp, Eric Perakslis, Timothy Taxter, Daniel J George
BACKGROUND: Roughly 5% of metastatic cancers present with uncertain origin, for which molecular classification could influence subsequent management; however, prior studies of molecular diagnostic classifiers have reported mixed results with regard to clinical impact. In this retrospective study, we evaluated the utility of a novel molecular diagnostic classifier by assessing theoretical changes in treatment and additional testing recommendations from oncologists before and after the review of classifier predictions...
September 15, 2023: Cancer Medicine