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Alcohol Research: Current Reviews

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https://read.qxmd.com/read/30557153/binge-drinking-s-effects-on-the-body
#1
Patricia E Molina, Steve Nelson
Studies have focused on the effects of chronic alcohol consumption and the mechanisms of tissue injury underlying alcoholic hepatitis and cirrhosis, with less focus on the pathophysiological consequences of binge alcohol consumption. Alcohol binge drinking prevalence continues to rise, particularly among individuals ages 18 to 24. However, it is also frequent in individuals ages 65 and older. High blood alcohol levels achieved with this pattern of alcohol consumption are of particular concern, as alcohol can permeate to virtually all tissues in the body, resulting in significant alterations in organ function, which leads to multisystemic pathophysiological consequences...
2018: Alcohol Research: Current Reviews
https://read.qxmd.com/read/30557152/nih-s-adolescent-brain-cognitive-development-abcd-study
#2
(no author information available yet)
No abstract text is available yet for this article.
2018: Alcohol Research: Current Reviews
https://read.qxmd.com/read/30557151/effects-of-binge-drinking-on-the-developing-brain
#3
Scott A Jones, Jordan M Lueras, Bonnie J Nagel
Binge drinking is a pattern of alcohol drinking that raises a person's blood alcohol concentration to at least .08%, which amounts to consuming five alcoholic drinks for men and four alcoholic drinks for women in about 2 hours. It is the most common form of alcohol misuse in adolescents and young adults. Heavy drinking includes the same criterion as binge drinking, but with higher frequency (i.e., 5 or more days in the past 30 days). Although binge drinking or heavy drinking alone is insufficient to meet the criteria for an alcohol use disorder (AUD) diagnosis, there are neurobiological changes, as well as an increased risk of developing an AUD later in life, associated with this form of alcohol misuse...
2018: Alcohol Research: Current Reviews
https://read.qxmd.com/read/30557150/binge-drinking-s-effects-on-the-developing-brain-animal-models
#4
Susanne Hiller-Sturmhöfel, Linda Patia Spear
Adolescence typically is a time of experimentation, including alcohol use and, particularly, binge drinking. Because the brain is still developing during adolescence, such exposure could have long-lasting effects. Animal models and adolescent intermittent ethanol exposure (AIE) paradigms have been used to help elucidate the consequences of adolescent binge drinking. These studies have identified cognitive deficits, particularly in challenging cognitive tasks, and behavioral alterations such as greater risk preferences, impulsivity, and disinhibition...
2018: Alcohol Research: Current Reviews
https://read.qxmd.com/read/30557149/gender-differences-in-binge-drinking
#5
Richard W Wilsnack, Sharon C Wilsnack, Gerhard Gmel, Lori Wolfgang Kantor
Just as binge drinking rates differ for men and women, the predictors and consequences of binge drinking vary by gender as well. This article examines these differences and how binge drinking definitions and research samples and methods may influence findings. It also describes the relationship between age and binge drinking among men and women, and how drinking culture and environment affect this relationship. It examines gender-specific trends in binge drinking, predictors of binge drinking for men and women, and binge drinking in the context of smoking...
2018: Alcohol Research: Current Reviews
https://read.qxmd.com/read/30557148/high-intensity-drinking
#6
Megan E Patrick, Beth Azar
Binge drinking thresholds have long been set at four or more drinks for women and five or more drinks for men over the course of a few hours. However, a significant number of people regularly consume much higher amounts of alcohol: double or even triple the standard binge drinking threshold. Researchers have begun to distinguish between typical binge drinking and this kind of "high-intensity drinking," which is common among certain types of binge drinkers and is often associated with special occasions, including holidays, sporting events, and, notably, 21st birthdays...
2018: Alcohol Research: Current Reviews
https://read.qxmd.com/read/30557147/niaaa-s-college-alcohol-intervention-matrix
#7
Jessica M Cronce, Traci L Toomey, Kathleen Lenk, Toben F Nelson, Jason R Kilmer, Mary E Larimer
The College Alcohol Intervention Matrix (CollegeAIM) is a user-friendly, interactive decision tool based on a synthesis of the substantial and growing literature on campus alcohol use prevention. It includes strategies targeted at both the individual and environmental levels. Commissioned by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), CollegeAIM reflects the collective knowledge of 16 separate experts in the field, which makes it unique relative to other summaries of the science. CollegeAIM is designed to help college stakeholders compare and contrast different evidence-based prevention strategies to select a mix of individual and environmental strategies that will work best on and around their campuses...
2018: Alcohol Research: Current Reviews
https://read.qxmd.com/read/30557146/-maturing-out-of-binge-and-problem-drinking
#8
Matthew R Lee, Kenneth J Sher
This article reviews literature aiming to explain the widespread reductions in binge and problem drinking that begin around the transition to young adulthood (i.e., "maturing out"). Whereas most existing literature on maturing out emphasizes contextual effects of transitions into adult roles and responsibilities, this article also reviews recent work demonstrating further effects of young adult personality maturation. As possible mechanisms of naturally occurring desistance, these processes could inform both public health and clinical interventions aimed at spurring similar types of drinking-related behavior change...
2018: Alcohol Research: Current Reviews
https://read.qxmd.com/read/30557145/the-epidemiology-of-binge-drinking-among-college-age-individuals-in-the-united-states
#9
Heather Krieger, Chelsie M Young, Amber M Anthenien, Clayton Neighbors
Rates of alcohol consumption continue to be a concern, particularly for individuals who are college age. Drinking patterns have changed over time, with the frequency of binge drinking (consuming four/five or more drinks for women/men) remaining high (30% to 40%). Young adults in the college age range are developmentally and socially at higher risk for drinking at binge levels. Changes in autonomy, parental control, norms, and attitudes affect binge drinking behaviors. This article reviews those changes, as well as the individual and environmental factors that increase or decrease the risk of participating in binge drinking behaviors...
2018: Alcohol Research: Current Reviews
https://read.qxmd.com/read/30557144/surveys-that-include-information-relevant-to-binge-drinking
#10
(no author information available yet)
No abstract text is available yet for this article.
2018: Alcohol Research: Current Reviews
https://read.qxmd.com/read/30557143/drinking-patterns-and-their-definitions
#11
(no author information available yet)
No abstract text is available yet for this article.
2018: Alcohol Research: Current Reviews
https://read.qxmd.com/read/30557142/adolescent-binge-drinking
#12
Tammy Chung, Kasey G Creswell, Rachel Bachrach, Duncan B Clark, Christopher S Martin
Binge drinking, commonly defined as consuming five or more standard drinks per occasion for men and four or more drinks for women, typically begins in adolescence. Adolescents, although they may drink less often, tend to consume higher quantities of alcohol per occasion compared with adults. This developmental difference in pattern of alcohol consumption may result, in part, from maturational changes that involve an adolescent-specific sensitivity to certain alcohol effects and greater propensity for risk-taking behaviors, such as binge drinking...
2018: Alcohol Research: Current Reviews
https://read.qxmd.com/read/30557141/binge-drinking
#13
Aaron M White, Susan Tapert, Shivendra D Shukla
No abstract text is available yet for this article.
2018: Alcohol Research: Current Reviews
https://read.qxmd.com/read/28988580/development-prevention-and-treatment-of-alcohol-induced-organ-injury-the-role-of-nutrition
#14
REVIEW
Shirish Barve, Shao-Yu Chen, Irina Kirpich, Walter H Watson, Craig Mcclain
Alcohol and nutrition have the potential to interact at multiple levels. For example, heavy alcohol consumption can interfere with normal nutrition, resulting in overall malnutrition or in deficiencies of important micronutrients, such as zinc, by reducing their absorption or increasing their loss. Interactions between alcohol consumption and nutrition also can affect epigenetic regulation of gene expression by influencing multiple regulatory mechanisms, including methylation and acetylation of histone proteins and DNA...
2017: Alcohol Research: Current Reviews
https://read.qxmd.com/read/28988579/alcohol-misuse-and-kidney-injury-epidemiological-evidence-and-potential-mechanisms
#15
REVIEW
Zoltan V Varga, Csaba Matyas, Janos Paloczi, Pal Pacher
Chronic alcohol consumption is a well-known risk factor for tissue injury. The link between alcohol use disorder (AUD) and kidney injury is intriguing but controversial, and the molecular mechanisms by which alcohol may damage the kidneys are poorly understood. Epidemiological studies attempting to link AUD and kidney disease are, to date, inconclusive, and there is little experimental evidence directly linking alcohol consumption to kidney injury. However, studies conducted primarily in other organs and tissues suggest several possible mechanisms by which alcohol may promote kidney dysfunction...
2017: Alcohol Research: Current Reviews
https://read.qxmd.com/read/28988578/alcohol-and-puberty
#16
REVIEW
William L Dees, Jill K Hiney, Vinod K Srivastava
Adolescence represents a vulnerable period for developing youth. Alcohol use and misuse are especially problematic behaviors during this time. Adolescents are more sensitive to alcohol and less tolerant of its detrimental effects than are adults. Research in humans and animals has revealed that early alcohol consumption can result in delayed pubertal development. Animal studies have shown that alcohol detrimentally affects neuroendocrine systems within the hypothalamic region of the brain that are associated with the normal, timely onset of the pubertal process...
2017: Alcohol Research: Current Reviews
https://read.qxmd.com/read/28988577/pathophysiology-of-the-effects-of-alcohol-abuse-on-the-endocrine-system
#17
REVIEW
Nadia Rachdaoui, Dipak K Sarkar
Alcohol can permeate virtually every organ and tissue in the body, resulting in tissue injury and organ dysfunction. Considerable evidence indicates that alcohol abuse results in clinical abnormalities of one of the body's most important systems, the endocrine system. This system ensures proper communication between various organs, also interfacing with the immune and nervous systems, and is essential for maintaining a constant internal environment. The endocrine system includes the hypothalamic-pituitary-adrenal axis, the hypothalamic-pituitary-gonadal axis, the hypothalamic-pituitary-thyroid axis, the hypothalamic-pituitary-growth hormone/insulin-like growth factor-1 axis, and the hypothalamic-posterior pituitary axis, as well as other sources of hormones, such as the endocrine pancreas and endocrine adipose tissue...
2017: Alcohol Research: Current Reviews
https://read.qxmd.com/read/28988576/alcohol-and-the-lung
#18
REVIEW
Ashish J Mehta, David M Guidot
Among the many organ systems affected by harmful alcohol use, the lungs are particularly susceptible to infections and injury. The mechanisms responsible for rendering people with alcohol use disorder (AUD) vulnerable to lung damage include alterations in host defenses of the upper and lower airways, disruption of alveolar epithelial barrier integrity, and alveolar macrophage immune dysfunction. Collectively, these derangements encompass what has been termed the "alcoholic lung" phenotype. Alcohol-related reductions in antioxidant levels also may contribute to lung disease in people with underlying AUD...
2017: Alcohol Research: Current Reviews
https://read.qxmd.com/read/28988575/alcohol-s-effects-on-the-cardiovascular-system
#19
REVIEW
Mariann R Piano
Alcohol use has complex effects on cardiovascular (CV) health. The associations between drinking and CV diseases such as hypertension, coronary heart disease, stroke, peripheral arterial disease, and cardiomyopathy have been studied extensively and are outlined in this review. Although many behavioral, genetic, and biologic variants influence the interconnection between alcohol use and CV disease, dose and pattern of alcohol consumption seem to modulate this most. Low-to-moderate alcohol use may mitigate certain mechanisms such as risk and hemostatic factors affecting atherosclerosis and inflammation, pathophysiologic processes integral to most CV disease...
2017: Alcohol Research: Current Reviews
https://read.qxmd.com/read/28988574/alcoholic-myopathy-pathophysiologic-mechanisms-and-clinical-implications
#20
REVIEW
Liz Simon, Sarah E Jolley, Patricia E Molina
Skeletal muscle dysfunction (i.e., myopathy) is common in patients with alcohol use disorder. However, few clinical studies have elucidated the significance, mechanisms, and therapeutic options of alcohol-related myopathy. Preclinical studies indicate that alcohol adversely affects both anabolic and catabolic pathways of muscle-mass maintenance and that an increased proinflammatory and oxidative milieu in the skeletal muscle is the primary contributing factor leading to alcohol-related skeletal muscle dysfunction...
2017: Alcohol Research: Current Reviews
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