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Case Reports in Dermatological Medicine

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https://read.qxmd.com/read/30719357/diagnosis-of-woolly-hair-using-trichoscopy
#1
Mahesh Mathur, Prakash Acharya, Alina Karki, Nisha Kc, Jyoti Shah
Hair shaft abnormalities including woolly hair are traditionally diagnosed by clinical examination and light microscopy which involves plucking of multiple hairs for examination. This is usually an inconvenient procedure especially in children. Trichoscopy may be a useful tool allowing close visualization of multiple hairs without causing discomfort to the patients. Trichoscopic findings of woolly hair have been described only in few reports. We report all of the trichoscopic findings of this rare disorder in one case which have only been reported separately in previous reports...
2019: Case Reports in Dermatological Medicine
https://read.qxmd.com/read/30693114/bathing-suit-variant-of-autosomal-recessive-congenital-ichthyosis-arci-in-two-indian-patients
#2
Dharshini Sathishkumar, Dincy Peter, Susanne Pulimood, Henning Wiegmann, Frederic Valentin, Meera Thomas, Hans Christian Hennies, Vinzenz Oji
Bathing suit ichthyosis (BSI) is a rare variant of autosomal recessive congenital ichthyosis (ARCI) due to transglutaminase-1 gene ( TGM1 ) mutations leading to a temperature sensitive phenotype. It is characterized by dark-grey or brownish scaling restricted to the "bathing suit" areas. We report two Indian girls with bathing suit ichthyosis and mutations in TGM1 (patient 1: homozygous for c.1147G>A; patient 2: compound heterozygous for c.832G>A, c.919C>G).
2018: Case Reports in Dermatological Medicine
https://read.qxmd.com/read/30662775/anogenital-ulcers-an-unusual-manifestation-of-invasive-aspergillosis
#3
Pablo Vargas, Fernando Valenzuela, Viera Kaplan, Jacob Yumha, Montserrat Arceu, Claudia Morales
Aspergillus spp. is one of the most ubiquitous fungi but generally does not cause disease in immunocompetent patients. It is the second most frequent agent of opportunistic fungal infections, after Candida albicans , with a rise in its incidence on recent years. Invasive fungal diseases represent an important cause of morbidity and mortality. Its origin can be primary, in relation to a cutaneous injury, or secondary, by extension from contiguous tissues, or by hematogenous spread, usually in the context of pulmonary aspergillosis...
2018: Case Reports in Dermatological Medicine
https://read.qxmd.com/read/30643651/a-case-series-of-bowen-s-disease-treated-with-the-combination-of-cryosurgery-and-ingenol-mebutate-and-followed-up-with-optical-coherence-tomography
#4
Georgios Gaitanis, Theodora Tsironi, Panagiota Spyridonos, Ioannis D Bassukas
Bowen's disease (BD) is a relatively rare in situ squamous cell carcinoma (SCC) with a limited potential of becoming invasive. Ingenol mebutate (IM) was relatively successful for the treatment of BD lesions in small case series. Optical coherence tomography (OCT) is a promising method for the diagnosis of cutaneous keratinocytic carcinomas, including BD. Herein we report the treatment of BD with the combination of cryosurgery and IM and the application of OCT imagining in treatment monitoring. Patients treated within a period of 12 months are retrospectively compiled...
2018: Case Reports in Dermatological Medicine
https://read.qxmd.com/read/30581634/mycosis-fungoides-involving-the-dorsal-tongue
#5
Ashley E Brown, Lindsey Schmidtberger, Kathleeen Kroger, Richard R Jahan-Tigh, Sarah S Pinney
Mycosis fungoides (MF) is a rare cutaneous T-cell lymphoma (CTCL) which can cause significant morbidity. During the disease course, it classically will progress through three clinical stages in the skin: patch-, plaque-, and tumor-stage. The early stages exhibit various histopathological mimics that often lead to misdiagnosis. It rarely affects the oral cavity. Oral MF is historically associated with poor prognosis. We present a rare case of MF afflicting the dorsal tongue and extremities of a 72-year-old male...
2018: Case Reports in Dermatological Medicine
https://read.qxmd.com/read/30538869/an-unusual-presentation-of-lupus-vulgaris-and-the-practical-usefulness-of-dermatoscopy
#6
Grigorios Theodosiou, Marina Papageorgiou, Ioanna Mandekou-Lefaki
We report a case report of lupus vulgaris (LV) presented on the extremities of an 80-year-old man. He was misdiagnosed as having psoriasis and referred to our department for a second-opinion evaluation. The discrepancy between the clinical manifestation which was misleading and the dermatoscopic findings raised the suspicion of an underlying granulomatous disease and we proceeded to skin biopsy. The histopathologic examination set the diagnosis of LV.
2018: Case Reports in Dermatological Medicine
https://read.qxmd.com/read/30510811/clinical-manifestation-dermoscopy-and-scanning-electron-microscopy-in-two-cases-of-contagious-ecthyma-orf-nodule
#7
Ana Laura Rosifini Alves Rezende, Fred Bernardes Filho, Natália Aparecida de Paula, Loan Towersey, Roderick Hay, Marco Andrey Cipriani Frade
Orf is a highly contagious skin disease commonly seen in goats and sheep that can be transmitted to people who have direct contact with infected animals. Here, we report the clinical manifestation, dermoscopy, and scanning electron microscopy in two women who developed skin lesions on their hands after handling goats with wounds in the udders. Human orf is usually self-limiting and no specific treatment is needed.
2018: Case Reports in Dermatological Medicine
https://read.qxmd.com/read/30254768/concurrent-diagnoses-of-cutaneous-sarcoidosis-and-recurrent-metastatic-breast-cancer-more-than-a-coincidental-occurrence
#8
Jacqueline Deen, Nick Mellick, Laura Wheller
Sarcoidosis is a rare, chronic, multisystem disease of unknown aetiology, characterised by non-caseating epithelioid cell granulomas. Its association with internal malignancy, in particular haematological cancers has been strongly documented in the literature, while its link with solid organ malignancies is less extensively reported. We present an atypical case of cutaneous sarcoidosis occurring in association with breast cancer recurrence in a 49-year-old female. Physician recognition of this link between sarcoidosis and internal malignancy is vital because many cases of sarcoidosis in association with neoplasia present initially, or even exclusively, with cutaneous sarcoidal lesions that may precede the development of cancer by several years, or as in our case, present as a cutaneous marker of concomitant underlying malignancy...
2018: Case Reports in Dermatological Medicine
https://read.qxmd.com/read/30245894/prurigo-nodularis-after-radiotherapy-an-isoradiotopic-response
#9
Caspar Weel Krammer, Rami Mossad Ibrahim
Prurigo nodularis is a rare and chronic skin disorder with multiple, pruritic, and firm nodules. The exact pathophysiology is still unknown. Skin disorders appearing at sites of radiation can be defined as isoradiotopic. A 35-year-old male had developed a skin lesion in the left submandibular area on a base of irradiated skin which was initially suspected as a skin malignancy. The patient had a history of undifferentiated nasopharyngeal cancer with lymph node involvement which was treated by radiochemotherapy thirteen years previously...
2018: Case Reports in Dermatological Medicine
https://read.qxmd.com/read/30174962/extensive-cutaneous-t-cell-lymphoma-of-the-feet-treated-with-high-dose-rate-brachytherapy-and-external-beam-radiation
#10
Joy Tao, Courtney Hentz, Michael L Mysz, Issra Rashed, David Eilers, James Swan, Rebecca Tung, Bahman Emami
Cutaneous T-cell lymphoma (CTCL) is a chronic, debilitating disease that has a severe impact on quality of life. We present a patient with multiple CTCL lesions on the bilateral feet, which impaired his ability to ambulate. His lesions on both feet were successfully treated with a total of 8 Gy in two fractions via high-dose-rate surface brachytherapy using the Freiburg Flap applicator. The deeper aspects of the bulkier lesions on the left foot were boosted with electron beam therapy. The radiation therapy was well tolerated, and the patient was able to regain his mobility after completing radiation therapy...
2018: Case Reports in Dermatological Medicine
https://read.qxmd.com/read/30147966/palliative-radiotherapy-for-disfiguring-mycosis-fungoides-lesion-a-key-treatment-to-reduce-psychological-and-social-impact
#11
Axel Egal, Caroline Ram-Wolf, Laurent Quero, Martine Bagot, Marie-Dominique Vignon-Pennamen, Christophe Hennequin, Basma M'Barek
Mycosis Fungoides (MF) is a rare disease with a relatively good prognosis at early stage. However, skin lesions can impair quality of life due to extensive skin lesions. In some cases, skin lesions, and especially those of the face, become visible and change the physical appearance of the patients. This aspect can deeply affect patients psychologically and can impact their social life. Here, we report the case of a patient with multiple lesions including a disfiguring lesion arising from the nose. The extent of his skin lesions gave a palliative intent to his treatment project...
2018: Case Reports in Dermatological Medicine
https://read.qxmd.com/read/30112222/dasatinib-induced-hypopigmentation-in-pediatric-patient-with-chronic-myeloid-leukemia-a-case-report-and-review-of-the-literature
#12
Bader Alharbi, Samer Alamri, Ahmed Mahdi, Siham Marghalani
Dasatinib is an oral second-generation multitarget tyrosine-kinase inhibitor (TKI) that is efficacious in treating imatinib-resistant chronic myeloid leukemia (CML) or intolerant cases. Noncutaneous adverse effects with dasatinib are well known in the literature, most commonly cytopenias and fluid retention, while pigmentary abnormalities have rarely been reported. We report the case of a 12-year-old male known case of CML, who presented to dermatology clinic approximately 2 years after initiating dasatinib treatment, with new-onset hypopigmentation of his upper limb, upper chest, and both knees of six months' duration...
2018: Case Reports in Dermatological Medicine
https://read.qxmd.com/read/30112221/vitiligo-appearing-after-oral-isotretinoin-therapy-for-acne
#13
Amal A Kokandi
Isotretinoin is an effective treatment for severe and scarring acne. In this report, we describe a case developing vitiligo after isotretinoin therapy for scarring acne. It is not known whether this was a coincidence or might be precipitated by the treatment.
2018: Case Reports in Dermatological Medicine
https://read.qxmd.com/read/30112220/erythema-dyschromicum-perstans-in-an-8-year-old-indian-child
#14
Alexander K C Leung, Joseph M Lam
We report an 8-year-old East Indian boy with erythema dyschromicum perstans. The condition has very rarely been reported in prepubertal Indian children. A perusal of the literature revealed but two cases, to which we add another one. Recognition of erythema dyschromicum perstans in prepubertal Indian children is important for proper diagnosis and to prevent unnecessary investigations.
2018: Case Reports in Dermatological Medicine
https://read.qxmd.com/read/30105102/prurigo-pigmentosa-a-clinicopathological-report-of-three-middle-eastern-patients
#15
N Almaani, A H Al-Tarawneh, H Msallam
Prurigo pigmentosa is a unique cutaneous inflammatory disorder characterized by a sudden onset of pruritic and erythematous macules, urticarial papules, and plaques that may coalesce to form a reticulated pattern. Lesions typically heal within weeks leaving a reticulated and mottled postinflammatory hyperpigmentation. The majority of reported cases originate from Japan with much fewer cases described worldwide without predominant ethnicity. The histopathological features of prurigo pigmentosa can be nonspecific; however, distinct features exist for each stage of the disease...
2018: Case Reports in Dermatological Medicine
https://read.qxmd.com/read/30046495/clozapine-induced-phototoxicity-an-unusual-side-effect-of-atypical-antipsychotics
#16
S Al-Aojan, A Al-Khalifah
Introduction: Clozapine is a second-generation antipsychotic used for treatment-refractory schizophrenia. Photosensitivity is a major concern when prescribing typical antipsychotics, while atypical antipsychotics are thought to be less photosensitive. Case Report: We report a 27-year-old military personnel who developed a phototoxic drug reaction after using clozapine for schizophrenia. Conclusion: Recognition of rare but possible ability of atypical antipsychotics to cause photosensitivity is pertinent to patients care and proper counseling...
2018: Case Reports in Dermatological Medicine
https://read.qxmd.com/read/30034888/extensive-cutaneous-scalp-angiosarcoma
#17
Zabeer Bhatti, Rameez Bhatti, Sharon Brangman, Kerry Whiting, Amit Dhamoon
Angiosarcoma is a cancer that is derived from endothelial cells that line blood vessels and lymphatic channels. Cutaneous angiosarcoma can appear anywhere on the skin and the clinical presentation is highly variable. Most cases appear on the scalp and face de novo. Our case describes a 91-year-old female with cutaneous scalp angiosarcoma. Our case serves to remind physicians that an abnormal skin finding in older adults should raise their index of suspicion for angiosarcoma and an early biopsy should be performed...
2018: Case Reports in Dermatological Medicine
https://read.qxmd.com/read/30026989/squamous-cell-carcinoma-arising-within-verruca-vulgaris-on-the-nipple
#18
Araya Zaesim, Amanda C Jackson, Sang Wook Lee, Shaun A Price
Cutaneous squamous cell carcinoma (SCC) is a common form of skin cancer and often appears as a hard, scaly lump that occasionally ulcerates. It is usually associated with cumulative exposure to ultraviolet light, although prior scarring, chronic wounds, exposure to radiation, HPV infection, and immunosuppression are also associated risk factors. Primary SCC of the nipple is very rare and only a few cases have been reported. We present a case of a 49-year-old female with concerns of a right nipple lesion with erythema and pain...
2018: Case Reports in Dermatological Medicine
https://read.qxmd.com/read/29992061/two-cases-of-pachydermodactyly-presenting-as-polyarthritis
#19
Roxana Mititelu, Sarah Finch, Paul Dancey, Ian Landells
Pachydermodactyly is characterized by asymptomatic, progressive swelling of the lateral aspects of the 2nd to 4th finger along the proximal interphalangeal (PIP) joint without involving the joint itself. We present 2 interesting cases of patients with periarticular swelling who were initially diagnosed and treated as juvenile idiopathic arthritis (JIA) with subsequent clinical and pathology confirmation of pachydermodactyly. These cases emphasize the importance of considering pachydermodactyly in young patients with development of periarticular swelling and no joint involvement...
2018: Case Reports in Dermatological Medicine
https://read.qxmd.com/read/29984008/asymmetric-bilateral-lichen-striatus-a-rare-presentation-following-multiple-blaschko-s-lines
#20
Jeffrey S Dickman, McKay D Frandsen, Andrew J Racette
Lichen striatus (LS) is an uncommon, acquired, self-limited, and benign linear dermatosis of unknown etiology that most often occurs unilaterally and is confined to the lines of Blaschko. A healthy 7-year-old girl presented to our clinic with bilateral asymmetric LS occurring on the right arm and left leg of 1-year duration. Very few cases of bilateral LS have been previously reported in the literature, with none from clinics within the United States. The etiology of LS is currently unknown; however its confinement to Blaschko's lines, which represent embryologic migration of skin cell clones, does provide insight into a possible pathogenesis...
2018: Case Reports in Dermatological Medicine
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