journal
https://read.qxmd.com/read/33825827/effects-of-slowmo-a-blended-digital-therapy-targeting-reasoning-on-paranoia-among-people-with-psychosis-a-randomized-clinical-trial
#1
Philippa Garety, Thomas Ward, Richard Emsley, Kathryn Greenwood, Daniel Freeman, David Fowler, Elizabeth Kuipers, Paul Bebbington, Mar Rus-Calafell, Alison McGourty, Catarina Sacadura, Nicola Collett, Kirsty James, Amy Hardy
Importance: Persistent paranoia is common among patients with psychosis. Cognitive-behavioral therapy for psychosis can be effective. However, challenges in engagement and effectiveness remain. Objective: To investigate the effects on paranoia and mechanisms of action of SlowMo, a digitally supported reasoning intervention, plus usual care compared with usual care only. Design, Setting, and Participants: This parallel-arm, assessor-blinded, randomized clinical trial recruited participants at UK community health services from May 1, 2017, to May 14, 2019...
April 7, 2021: JAMA Psychiatry
https://read.qxmd.com/read/33825824/errors-in-text
#2
(no author information available yet)
No abstract text is available yet for this article.
April 7, 2021: JAMA Psychiatry
https://read.qxmd.com/read/33825819/a-new-consensus-framework-for-phenotyping-and-treatment-selecting-in-addiction-and-obsessive-compulsive-related-disorders
#3
Murat Yücel, Rico S C Lee, Leonardo F Fontenelle
No abstract text is available yet for this article.
April 7, 2021: JAMA Psychiatry
https://read.qxmd.com/read/33787853/discriminating-heterogeneous-trajectories-of-resilience-and-depression-after-major-life-stressors-using-polygenic-scores
#4
Katharina Schultebraucks, Karmel W Choi, Isaac R Galatzer-Levy, George A Bonanno
Importance: Major life stressors, such as loss and trauma, increase the risk of depression. It is known that individuals show heterogeneous trajectories of depressive symptoms following major life stressors, including chronic depression, recovery, and resilience. Although common genetic variation has been associated with depression risk, genomic factors that could help discriminate trajectories of risk vs resilience following adversity have not been identified. Objective: To assess the discriminatory accuracy of a deep neural net combining joint information from 21 psychiatric and health-related multiple polygenic scores (PGSs) for discriminating resilience vs other longitudinal symptom trajectories with use of longitudinal, genetically informed data on adults exposed to major life stressors...
March 31, 2021: JAMA Psychiatry
https://read.qxmd.com/read/33787832/cost-effectiveness-of-treatments-for-opioid-use-disorder
#5
Michael Fairley, Keith Humphreys, Vilija R Joyce, Mark Bounthavong, Jodie Trafton, Ann Combs, Elizabeth M Oliva, Jeremy D Goldhaber-Fiebert, Steven M Asch, Margaret L Brandeau, Douglas K Owens
Importance: Opioid use disorder (OUD) is a significant cause of morbidity and mortality in the US, yet many individuals with OUD do not receive treatment. Objective: To assess the cost-effectiveness of OUD treatments and association of these treatments with outcomes in the US. Design and Setting: This model-based cost-effectiveness analysis included a US population with OUD. Interventions: Medication-assisted treatment (MAT) with buprenorphine, methadone, or injectable extended-release naltrexone; psychotherapy (beyond standard counseling); overdose education and naloxone distribution (OEND); and contingency management (CM)...
March 31, 2021: JAMA Psychiatry
https://read.qxmd.com/read/33787824/psychiatry-and-deaths-of-despair
#6
Lilly Shanahan, William E Copeland
No abstract text is available yet for this article.
March 31, 2021: JAMA Psychiatry
https://read.qxmd.com/read/33769431/how-covid-19-affects-the-brain
#7
Maura Boldrini, Peter D Canoll, Robyn S Klein
No abstract text is available yet for this article.
March 26, 2021: JAMA Psychiatry
https://read.qxmd.com/read/33760059/data-errors-in-table
#8
(no author information available yet)
No abstract text is available yet for this article.
March 24, 2021: JAMA Psychiatry
https://read.qxmd.com/read/33760055/jama-psychiatry-the-year-in-review-2020
#9
Dost Öngür
No abstract text is available yet for this article.
March 24, 2021: JAMA Psychiatry
https://read.qxmd.com/read/33760039/risk-of-suicide-attempt-in-patients-with-recent-diagnosis-of-mild-cognitive-impairment-or-dementia
#10
Mia Maria Günak, Deborah E Barnes, Kristine Yaffe, Yixia Li, Amy L Byers
Importance: Little is known about the association between mild cognitive impairment (MCI) and suicide. Most studies have focused on dementia and suicidal behavior, with inconsistent results. Objectives: To examine the association between diagnoses of MCI and dementia and suicide attempt and explore potential psychiatric moderators and to assess whether the association differs based on recency of diagnosis. Design, Setting, and Participants: This nationwide cohort study integrated 5 national databases from the Department of Veterans Affairs (VA) and Centers for Medicare & Medicaid Services and included all VA medical centers in the US...
March 24, 2021: JAMA Psychiatry
https://read.qxmd.com/read/33760038/error-in-figure-3
#11
(no author information available yet)
No abstract text is available yet for this article.
March 24, 2021: JAMA Psychiatry
https://read.qxmd.com/read/33729460/caring-for-the-patient-with-catatonia
#12
Stephan Heckers, Sebastian Walther
No abstract text is available yet for this article.
March 17, 2021: JAMA Psychiatry
https://read.qxmd.com/read/33729432/accuracy-requirements-for-cost-effective-suicide-risk-prediction-among-primary-care-patients-in-the-us
#13
Eric L Ross, Kelly L Zuromski, Ben Y Reis, Matthew K Nock, Ronald C Kessler, Jordan W Smoller
Importance: Several statistical models for predicting suicide risk have been developed, but how accurate such models must be to warrant implementation in clinical practice is not known. Objective: To identify threshold values of sensitivity, specificity, and positive predictive value that a suicide risk prediction method must attain to cost-effectively target a suicide risk reduction intervention to high-risk individuals. Design, Setting, and Participants: This economic evaluation incorporated published data on suicide epidemiology, the health care and societal costs of suicide, and the costs and efficacy of suicide risk reduction interventions into a novel decision analytic model...
March 17, 2021: JAMA Psychiatry
https://read.qxmd.com/read/33729431/three-important-considerations-for-studies-examining-pathophysiological-pathways-in-psychiatric-illness-in-depth-phenotyping-biological-assessment-and-causal-inferences
#14
Mary L Phillips, Kenneth S Kendler
No abstract text is available yet for this article.
March 17, 2021: JAMA Psychiatry
https://read.qxmd.com/read/33688938/age-specific-prevalence-and-incidence-of-dementia-diagnoses-among-older-us-adults-with-schizophrenia
#15
T Scott Stroup, Mark Olfson, Cecilia Huang, Melanie M Wall, Terry Goldberg, Davangere P Devanand, Tobias Gerhard
Importance: People with schizophrenia are at high risk of receiving a diagnosis of dementia. Understanding the magnitude and timing of this increased risk has important implications for practice and policy. Objective: To estimate the age-specific incidence and prevalence of dementia diagnoses among older US adults with schizophrenia and in a comparison group without serious mental illness (SMI). Design, Setting, and Participants: This retrospective cohort study used a 50% random national sample of Medicare beneficiaries 66 years or older with fee-for-service plans and Part D prescription drug coverage from January 1, 2007, to December 31, 2017...
March 10, 2021: JAMA Psychiatry
https://read.qxmd.com/read/33688937/top-down-and-bottom-up-pathways-to-developing-psychological-interventions
#16
Ioana A Cristea, Tomaso Vecchi, Pim Cuijpers
No abstract text is available yet for this article.
March 10, 2021: JAMA Psychiatry
https://read.qxmd.com/read/33688928/association-of-antihypertensive-drug-target-genes-with-psychiatric-disorders-a-mendelian-randomization-study
#17
Solal Chauquet, Zhihong Zhu, Michael C O'Donovan, James T R Walters, Naomi R Wray, Sonia Shah
Importance: Observational studies have reported associations between antihypertensive medication and psychiatric disorders, although the reported direction of association appears to be dependent on drug class. Objective: To estimate the potential effect of different antihypertensive drug classes on schizophrenia, bipolar disorder, and major depressive disorder. Design, Setting, and Participants: This 2-sample mendelian randomization study assessed the association between a single-nucleotide variant (SNV) and drug target gene expression derived from existing expression quantitative trait loci (eQTL) data in blood (sample 1) and the SNV-disease association from published case-control genome-wide association studies (sample 2)...
March 10, 2021: JAMA Psychiatry
https://read.qxmd.com/read/33656561/effect-of-incentives-for-alcohol-abstinence-in-partnership-with-3-american-indian-and-alaska-native-communities-a-randomized-clinical-trial
#18
Michael G McDonell, Katherine A Hirchak, Jalene Herron, Abram J Lyons, Karl C Alcover, Jennifer Shaw, Gordon Kordas, Lisa G Dirks, Kelley Jansen, Jaedon Avey, Kate Lillie, Dennis Donovan, Sterling M McPherson, Denise Dillard, Richard Ries, John Roll, Dedra Buchwald
Importance: Many American Indian and Alaska Native communities are disproportionately affected by problems with alcohol use and seek culturally appropriate and effective interventions for individuals with alcohol use disorders. Objective: To determine whether a culturally tailored contingency management intervention, in which incentives were offered for biologically verified alcohol abstinence, resulted in increased abstinence among American Indian and Alaska Native adults...
March 3, 2021: JAMA Psychiatry
https://read.qxmd.com/read/33656549/error-in-figure
#19
(no author information available yet)
No abstract text is available yet for this article.
March 3, 2021: JAMA Psychiatry
https://read.qxmd.com/read/33656541/bringing-together-behavioral-science-community-engagement-and-cultural-adaptations-to-increase-alcohol-abstinence-among-american-indian-and-alaska-native-people-using-contingency-management-therapy
#20
Stephanie S O'Malley, Maria C Crouch, Stephen T Higgins
No abstract text is available yet for this article.
March 3, 2021: JAMA Psychiatry
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