journal

JAMA Neurology

journal
https://read.qxmd.com/read/31682711/error-in-affiliation
#1
(no author information available yet)
No abstract text is available yet for this article.
November 4, 2019: JAMA Neurology
https://read.qxmd.com/read/31682709/distinctive-magnetic-resonance-imaging-findings-in-iglon5-antibody-disease
#2
Han Chen, Jinze Wu, Sarosh R Irani
No abstract text is available yet for this article.
November 4, 2019: JAMA Neurology
https://read.qxmd.com/read/31682684/are-daylight-saving-time-changes-bad-for-the-brain
#3
Beth A Malow, Olivia J Veatch, Kanika Bagai
No abstract text is available yet for this article.
November 4, 2019: JAMA Neurology
https://read.qxmd.com/read/31682678/associations-between-vascular-risk-across-adulthood-and-brain-pathology-in-late-life-evidence-from-a-british-birth-cohort
#4
Christopher A Lane, Josephine Barnes, Jennifer M Nicholas, Carole H Sudre, David M Cash, Ian B Malone, Thomas D Parker, Ashvini Keshavan, Sarah M Buchanan, Sarah E Keuss, Sarah-Naomi James, Kirsty Lu, Heidi Murray-Smith, Andrew Wong, Elizabeth Gordon, William Coath, Marc Modat, David Thomas, Marcus Richards, Nick C Fox, Jonathan M Schott
Importance: Midlife vascular risk burden is associated with late-life dementia. Less is known about if and how risk exposure in early adulthood influences late-life brain health. Objective: To determine the associations between vascular risk in early adulthood, midlife, and late life with late-life brain structure and pathology using measures of white matter-hyperintensity volume, β-amyloid load, and whole-brain and hippocampal volumes. Design, Setting, and Participants: This prospective longitudinal cohort study, Insight 46, is part of the Medical Research Council National Survey of Health and Development, which commenced in 1946...
November 4, 2019: JAMA Neurology
https://read.qxmd.com/read/31682673/prevention-of-dementia-thinking-beyond-the-age-and-amyloid-boxes
#5
Sudha Seshadri
No abstract text is available yet for this article.
November 4, 2019: JAMA Neurology
https://read.qxmd.com/read/31657834/selective-vulnerability-of-the-nucleus-basalis-of-meynert-among-neuropathologic-subtypes-of-alzheimer-disease
#6
Fadi S Hanna Al-Shaikh, Ranjan Duara, Julia E Crook, Elizabeth R Lesser, Jolien Schaeverbeke, Kelly M Hinkle, Owen A Ross, Nilufer Ertekin-Taner, Otto Pedraza, Dennis W Dickson, Neill R Graff-Radford, Melissa E Murray
Importance: Corticolimbic patterns of neurofibrillary tangle (NFT) accumulation define neuropathologic subtypes of Alzheimer disease (AD), which underlie the clinical heterogeneity observed antemortem. The cholinergic system, which is the target of acetylcholinesterase inhibitor therapy, is selectively vulnerable in AD. Objective: To investigate the major source of cholinergic innervation, the nucleus basalis of Meynert (nbM), in order to determine whether there is differential involvement of NFT accumulation or neuronal loss among AD subtypes...
October 28, 2019: JAMA Neurology
https://read.qxmd.com/read/31657826/coexistence-of-myelin-oligodendrocyte-glycoprotein-and-aquaporin-4-antibodies-in-adult-and-pediatric-patients
#7
Amy Kunchok, John J Chen, Andrew McKeon, John R Mills, Eoin P Flanagan, Sean J Pittock
No abstract text is available yet for this article.
October 28, 2019: JAMA Neurology
https://read.qxmd.com/read/31657825/epidemiology-of-dementia-and-alzheimer-disease-in-individuals-with-down-syndrome
#8
Eric Rubenstein, Sigan Hartley, Lauren Bishop
No abstract text is available yet for this article.
October 28, 2019: JAMA Neurology
https://read.qxmd.com/read/31657824/the-mask-sign-an-imaging-marker-of-traumatic-spinal-cord-hemorrhage
#9
Jacqueline C Junn, Jason Talbott, Jared Narvid
No abstract text is available yet for this article.
October 28, 2019: JAMA Neurology
https://read.qxmd.com/read/31633748/error-in-byline
#10
(no author information available yet)
No abstract text is available yet for this article.
October 21, 2019: JAMA Neurology
https://read.qxmd.com/read/31633742/interrater-reliability-of-experts-in-identifying-interictal-epileptiform-discharges-in-electroencephalograms
#11
Jin Jing, Aline Herlopian, Ioannis Karakis, Marcus Ng, Jonathan J Halford, Alice Lam, Douglas Maus, Fonda Chan, Marjan Dolatshahi, Carlos Muniz, Catherine Chu, Valeria Sacca, Jay Pathmanathan, WenDong Ge, Haoqi Sun, Justin Dauwels, Andrew J Cole, Daniel B Hoch, Sydney S Cash, M Brandon Westover
Importance: The validity of using electroencephalograms (EEGs) to diagnose epilepsy requires reliable detection of interictal epileptiform discharges (IEDs). Prior interrater reliability (IRR) studies are limited by small samples and selection bias. Objective: To assess the reliability of experts in detecting IEDs in routine EEGs. Design, Setting, and Participants: This prospective analysis conducted in 2 phases included as participants physicians with at least 1 year of subspecialty training in clinical neurophysiology...
October 21, 2019: JAMA Neurology
https://read.qxmd.com/read/31633741/incorrect-affiliation
#12
(no author information available yet)
No abstract text is available yet for this article.
October 21, 2019: JAMA Neurology
https://read.qxmd.com/read/31633740/development-of-expert-level-automated-detection-of-epileptiform-discharges-during-electroencephalogram-interpretation
#13
Jin Jing, Haoqi Sun, Jennifer A Kim, Aline Herlopian, Ioannis Karakis, Marcus Ng, Jonathan J Halford, Douglas Maus, Fonda Chan, Marjan Dolatshahi, Carlos Muniz, Catherine Chu, Valeria Sacca, Jay Pathmanathan, Wendong Ge, Justin Dauwels, Alice Lam, Andrew J Cole, Sydney S Cash, M Brandon Westover
Importance: Interictal epileptiform discharges (IEDs) in electroencephalograms (EEGs) are a biomarker of epilepsy, seizure risk, and clinical decline. However, there is a scarcity of experts qualified to interpret EEG results. Prior attempts to automate IED detection have been limited by small samples and have not demonstrated expert-level performance. There is a need for a validated automated method to detect IEDs with expert-level reliability. Objective: To develop and validate a computer algorithm with the ability to identify IEDs as reliably as experts and classify an EEG recording as containing IEDs vs no IEDs...
October 21, 2019: JAMA Neurology
https://read.qxmd.com/read/31633735/a-rare-form-of-lipid-metabolic-encephalopathy
#14
Qian Qian, Du Cao, You-Dong Wei
No abstract text is available yet for this article.
October 21, 2019: JAMA Neurology
https://read.qxmd.com/read/31621797/ethical-challenges-of-risk-informed-consent-and-posttrial-responsibilities-in-human-research-with-neural-devices-a-review
#15
Saskia Hendriks, Christine Grady, Khara M Ramos, Winston Chiong, Joseph J Fins, Paul Ford, Sara Goering, Henry T Greely, Katrina Hutchison, Michael L Kelly, Scott Y H Kim, Eran Klein, Sarah H Lisanby, Helen Mayberg, Hannah Maslen, Franklin G Miller, Karen Rommelfanger, Sameer A Sheth, Anna Wexler
Importance: Developing more and better diagnostic and therapeutic tools for central nervous system disorders is an ethical imperative. Human research with neural devices is important to this effort and a critical focus of the National Institutes of Health Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative. Despite regulations and standard practices for conducting ethical research, researchers and others seek more guidance on how to ethically conduct neural device studies...
October 17, 2019: JAMA Neurology
https://read.qxmd.com/read/31609383/mendelian-randomization-a-journey-from-obscurity-to-center-stage-with-a-few-potholes-along-the-way
#16
Sara Bandres-Ciga, Alastair J Noyce, Bryan J Traynor
No abstract text is available yet for this article.
October 14, 2019: JAMA Neurology
https://read.qxmd.com/read/31609382/cautious-interpretation-of-observational-data-reply
#17
Katharine E Harding, Emma C Tallantyre, Neil P Robertson
No abstract text is available yet for this article.
October 14, 2019: JAMA Neurology
https://read.qxmd.com/read/31609381/endovascular-therapy-for-childhood-stroke-working-together-to-reach-prime-time
#18
Christine Fox, Nomazulu Dlamini
No abstract text is available yet for this article.
October 14, 2019: JAMA Neurology
https://read.qxmd.com/read/31609380/feasibility-safety-and-outcome-of-endovascular-recanalization-in-childhood-stroke-the-save-childs-study
#19
Peter B Sporns, Ronald Sträter, Jens Minnerup, Heinz Wiendl, Uta Hanning, René Chapot, Hans Henkes, Elina Henkes, Astrid Grams, Franziska Dorn, Omid Nikoubashman, Martin Wiesmann, Georg Bier, Anushe Weber, Gabriel Broocks, Jens Fiehler, Alex Brehm, Marios Psychogios, Daniel Kaiser, Umut Yilmaz, Andrea Morotti, Wolfgang Marik, Richard Nolz, Ulf Jensen-Kondering, Bernd Schmitz, Stefan Schob, Oliver Beuing, Friedrich Götz, Johannes Trenkler, Bernd Turowski, Markus Möhlenbruch, Christina Wendl, Peter Schramm, Patricia Musolino, Sarah Lee, Marc Schlamann, Alexander Radbruch, Nicole Rübsamen, André Karch, Walter Heindel, Moritz Wildgruber, André Kemmling
Importance: Randomized clinical trials have shown the efficacy of thrombectomy of large intracranial vessel occlusions in adults; however, any association of therapy with clinical outcomes in children is unknown. Objective: To evaluate the use of endovascular recanalization in pediatric patients with arterial ischemic stroke. Design, Setting, and Participants: This retrospective, multicenter cohort study, conducted from January 1, 2000, to December 31, 2018, analyzed the databases from 27 stroke centers in Europe and the United States...
October 14, 2019: JAMA Neurology
https://read.qxmd.com/read/31609379/cautious-interpretation-of-observational-data
#20
Ricardo Soares-Dos-Reis, Silvia Messina
No abstract text is available yet for this article.
October 14, 2019: JAMA Neurology
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