journal
https://read.qxmd.com/read/38885009/%C3%AE-amyloid-in-cognitively-unimpaired-individuals-blame-mom
#1
JOURNAL ARTICLE
Dena B Dubal, Holly C Elser
No abstract text is available yet for this article.
June 17, 2024: JAMA Neurology
https://read.qxmd.com/read/38884991/medical-forecasting-a-skill-set-worthy-of-attention
#2
JOURNAL ARTICLE
Claire J Creutzfeldt, Robert G Holloway
No abstract text is available yet for this article.
June 17, 2024: JAMA Neurology
https://read.qxmd.com/read/38884986/angiotensin-receptor-blockers-for-hypertension-and-risk-of-epilepsy
#3
JOURNAL ARTICLE
Xuerong Wen, Marianne N Otoo, Jie Tang, Todd Brothers, Kristina E Ward, Nicole Asal, Kimford J Meador
IMPORTANCE: Animal and human studies have suggested that the use of angiotensin receptor blockers (ARBs) may be associated with a lower risk of incident epilepsy compared with other antihypertensive medications. However, observational data from the US are lacking. OBJECTIVE: To evaluate the association between ARB use and epilepsy incidence in subgroups of US patients with hypertension. DESIGN, SETTING, AND PARTICIPANTS: This retrospective cohort study used data from a national health administrative database from January 2010 to December 2017 with propensity score (PS) matching...
June 17, 2024: JAMA Neurology
https://read.qxmd.com/read/38884955/parental-history-of-memory-impairment-and-%C3%AE-amyloid-in-cognitively-unimpaired-older-adults
#4
JOURNAL ARTICLE
Mabel Seto, Timothy J Hohman, Elizabeth C Mormino, Kathryn V Papp, Rebecca E Amariglio, Dorene M Rentz, Keith A Johnson, Aaron P Schultz, Reisa A Sperling, Rachel F Buckley, Hyun-Sik Yang
IMPORTANCE: Studies have suggested that maternal history of late-onset Alzheimer disease, but not paternal, predisposes individuals to higher brain β-amyloid (Aβ) burden, reduced brain metabolism, and lower gray matter volumes. OBJECTIVE: To characterize maternal vs paternal history of memory impairment in terms of brain Aβ-positron emission tomography (Aβ-PET) and baseline cognition among a large sample of cognitively unimpaired older adults...
June 17, 2024: JAMA Neurology
https://read.qxmd.com/read/38857029/tau-positron-emission-tomography-for-predicting-dementia-in-individuals-with-mild-cognitive-impairment
#5
JOURNAL ARTICLE
Colin Groot, Ruben Smith, Lyduine E Collij, Sophie E Mastenbroek, Erik Stomrud, Alexa Pichet Binette, Antoine Leuzy, Sebastian Palmqvist, Niklas Mattsson-Carlgren, Olof Strandberg, Hanna Cho, Chul Hyoung Lyoo, Giovanni B Frisoni, Debora E Peretti, Valentina Garibotto, Renaud La Joie, David N Soleimani-Meigooni, Gil Rabinovici, Rik Ossenkoppele, Oskar Hansson
IMPORTANCE: An accurate prognosis is especially pertinent in mild cognitive impairment (MCI), when individuals experience considerable uncertainty about future progression. OBJECTIVE: To evaluate the prognostic value of tau positron emission tomography (PET) to predict clinical progression from MCI to dementia. DESIGN, SETTING, AND PARTICIPANTS: This was a multicenter cohort study with external validation and a mean (SD) follow-up of 2.0 (1...
June 10, 2024: JAMA Neurology
https://read.qxmd.com/read/38857026/incorrect-nomenclature-may-lead-to-questionable-concepts
#6
JOURNAL ARTICLE
Carsten A Wagner
No abstract text is available yet for this article.
June 10, 2024: JAMA Neurology
https://read.qxmd.com/read/38857022/bilateral-calcification-of-the-meckel-cave-causing-hemicrania-continua
#7
JOURNAL ARTICLE
Cristian Eduardo Navarro
No abstract text is available yet for this article.
June 10, 2024: JAMA Neurology
https://read.qxmd.com/read/38857015/acetaminophen-and-ibuprofen-in-pediatric-central-nervous-system-malaria-a-randomized-clinical-trial
#8
JOURNAL ARTICLE
Gretchen L Birbeck, Karl B Seydel, Suzanna Mwanza, Derby Tembo, Moses Chilombe, Arthur Watts, Ifunanya Ume-Ezeoke, Manoj Mathews, Archana A Patel, Musaku Mwenechanya, Paul Pensulo, Michael P McDermott
IMPORTANCE: A third of children who survive malaria with neurological involvement (central nervous system [CNS] malaria) develop sequelae. A higher maximum temperature (Tmax) and seizures are risk factors for sequelae. OBJECTIVE: To compare aggressive antipyretic therapy using scheduled acetaminophen and ibuprofen vs usual care with acetaminophen alone given only for a temperature of 38.5 °C or higher. DESIGN, SETTING, AND PARTICIPANTS: This randomized clinical trial was conducted at inpatient pediatric services of 1 tertiary care and 1 district hospital in Zambia and a tertiary care center in Malawi...
June 10, 2024: JAMA Neurology
https://read.qxmd.com/read/38856983/cerebral-amyloid-angiopathy-and-nontraumatic-subdural-hemorrhage-reply
#9
JOURNAL ARTICLE
Cyprien A Rivier, Guido J Falcone, Santosh B Murthy
No abstract text is available yet for this article.
June 10, 2024: JAMA Neurology
https://read.qxmd.com/read/38856979/cerebral-amyloid-angiopathy-and-nontraumatic-subdural-hemorrhage
#10
JOURNAL ARTICLE
Francesco Bax, Steven M Greenberg
No abstract text is available yet for this article.
June 10, 2024: JAMA Neurology
https://read.qxmd.com/read/38829667/status-epilepticus-identification-and-treatment-among-emergency-medical-services-agencies
#11
JOURNAL ARTICLE
Andrew J Wood, James F Burke, Daniel H Lowenstein, Elan L Guterman
No abstract text is available yet for this article.
June 3, 2024: JAMA Neurology
https://read.qxmd.com/read/38829666/time-to-think-about-myocardial-infarction-in-acute-ischemic-stroke
#12
JOURNAL ARTICLE
Alison Seitz, Alexander E Merkler
No abstract text is available yet for this article.
June 3, 2024: JAMA Neurology
https://read.qxmd.com/read/38829660/time-from-hospital-arrival-until-endovascular-thrombectomy-and-patient-reported-outcomes-in-acute-ischemic-stroke
#13
JOURNAL ARTICLE
Raed A Joundi, Eric E Smith, Aravind Ganesh, Raul G Nogueira, Ryan A McTaggart, Andrew M Demchuk, Alexandre Y Poppe, Jeremy L Rempel, Thalia S Field, Dar Dowlatshahi, Jim Sahlas, Richard Swartz, Ruchir Shah, Eric Sauvageau, Volker Puetz, Frank L Silver, Bruce Campbell, René Chapot, Michael Tymianski, Mayank Goyal, Michael D Hill
IMPORTANCE: The time-benefit association of endovascular thrombectomy (EVT) in ischemic stroke with patient-reported outcomes is unknown. OBJECTIVE: To assess the time-dependent association of EVT with self-reported quality of life in patients with acute ischemic stroke. DESIGN, SETTING, AND PARTICIPANTS: Data were used from the Safety and Efficacy of Nerinetide in Subjects Undergoing Endovascular Thrombectomy for Stroke (ESCAPE-NA1) trial, which tested the effect of nerinetide on functional outcomes in patients with large vessel occlusion undergoing EVT and enrolled patients from March 1, 2017, to August 12, 2019...
June 3, 2024: JAMA Neurology
https://read.qxmd.com/read/38829651/temperature-control-after-cardiac-arrest-a-rational-approach
#14
JOURNAL ARTICLE
Daniel S Harrison, David M Greer
No abstract text is available yet for this article.
June 3, 2024: JAMA Neurology
https://read.qxmd.com/read/38829625/type-1-myocardial-infarction-in-patients-with-acute-ischemic-stroke
#15
JOURNAL ARTICLE
Christian H Nolte, Regina von Rennenberg, Simon Litmeier, David M Leistner, Kristina Szabo, Stefan Baumann, Annerose Mengel, Dominik Michalski, Timo Siepmann, Stephan Blankenberg, Gabor C Petzold, Martin Dichgans, Hugo Katus, Burkert Pieske, Vera Regitz-Zagrosek, Tim Bastian Braemswig, Ida Rangus, Amra Pepic, Eik Vettorazzi, Andreas M Zeiher, Jan F Scheitz, Karl Wegscheider, Ulf Landmesser, Matthias Endres
IMPORTANCE: Elevated values of high-sensitivity cardiac troponin (hs-cTn) are common in patients with acute ischemic stroke and are associated with poor prognosis. However, diagnostic and therapeutic implications in patients with ischemic stroke remain unclear. OBJECTIVE: To identify factors indicative of myocardial infarction (MI) in patients with acute ischemic stroke and hs-cTn elevation. The primary hypothesis was that a dynamic change of hs-cTn values (>50% change) in patients with acute ischemic stroke indicates MI...
June 3, 2024: JAMA Neurology
https://read.qxmd.com/read/38805232/isolated-diffuse-precentral-gyrus-signals-in-creutzfeldt-jakob-disease
#16
JOURNAL ARTICLE
Zhongyun Chen, Zhen Wang, Liyong Wu
No abstract text is available yet for this article.
May 28, 2024: JAMA Neurology
https://read.qxmd.com/read/38805216/immediate-or-delayed-intensive-statin-in-acute-cerebral-ischemia-the-inspires-randomized-clinical-trial
#17
JOURNAL ARTICLE
Ying Gao, Lingling Jiang, Yuesong Pan, Weiqi Chen, Jing Jing, Chunjuan Wang, S Claiborne Johnston, Pierre Amarenco, Philip M Bath, Yingying Yang, Tingting Wang, Shangrong Han, Xia Meng, Jinxi Lin, Xingquan Zhao, Liping Liu, Jinguo Zhao, Ying Li, Yingzhuo Zang, Shuo Zhang, Hongqin Yang, Jianbo Yang, Yuanwei Wang, Dali Li, Yanxia Wang, Dongqi Liu, Guangming Kang, Yongjun Wang, Yilong Wang
IMPORTANCE: Comparisons are limited for immediate-intensive and delayed-intensive statin for secondary stroke prevention and neuroprotection in patients with acute mild ischemic stroke or transient ischemic attack (TIA) from atherosclerosis. OBJECTIVE: To estimate whether immediate-intensive statin therapy is safe and can lower the risk of recurrent stroke compared with delayed-intensive statin in patients with acute mild ischemic stroke or high-risk TIA from atherosclerosis...
May 28, 2024: JAMA Neurology
https://read.qxmd.com/read/38805215/time-windows-between-symptom-onset-and-treatment-an-outdated-myth
#18
JOURNAL ARTICLE
Louis R Caplan
No abstract text is available yet for this article.
May 28, 2024: JAMA Neurology
https://read.qxmd.com/read/38805207/early-vs-late-anticoagulation-in-minor-moderate-and-major-ischemic-stroke-with-atrial-fibrillation-post-hoc-analysis-of-the-elan-randomized-clinical-trial
#19
JOURNAL ARTICLE
Martina B Goeldlin, Arsany Hakim, Mattia Branca, Stefanie Abend, Markus Kneihsl, Waldo Valenzuela Pinilla, Sabine Fenzl, Beata Rezny-Kasprzak, Roman Rohner, Daniel Strbian, Maurizio Paciaroni, Goetz Thomalla, Patrik Michel, Krassen Nedeltchev, Thomas Gattringer, Else Charlotte Sandset, Leo Bonati, Diana Aguiar de Sousa, P N Sylaja, George Ntaios, Masatoshi Koga, Zuzana Gdovinova, Robin Lemmens, Natan M Bornstein, Peter Kelly, Mira Katan, Thomas Horvath, Jesse Dawson, Urs Fischer
IMPORTANCE: Whether infarct size modifies the treatment effect of early vs late direct oral anticoagulant (DOAC) initiation in people with ischemic stroke and atrial fibrillation is unknown. OBJECTIVE: To assess whether infarct size modifies the safety and efficacy of early vs late DOAC initiation. DESIGN, SETTING, AND PARTICIPANTS: Post hoc analysis of participants from the multinational (>100 sites in 15 countries) randomized clinical Early Versus Later Anticoagulation for Stroke With Atrial Fibrillation (ELAN) trial who had (1) acute ischemic stroke, (2) atrial fibrillation, and (3) brain imaging available before randomization...
May 28, 2024: JAMA Neurology
https://read.qxmd.com/read/38778793/early-access-to-first-seizure-clinics-subsequent-outcomes-and-factors-associated-with-attendance
#20
JOURNAL ARTICLE
Yingtong Li, Tianrui Ren, Michael Burgess, Zhibin Chen, Patrick W Carney, Terence J O'Brien, Patrick Kwan, Emma Foster
IMPORTANCE: First-seizure clinics (FSCs) aim to deliver prompt specialist care to patients with new-onset undifferentiated seizure events. OBJECTIVE: To determine whether FSC attendance and time to FSC are associated with subsequent health care utilization and mortality and to investigate factors associated with FSC nonattendance. DESIGN, SETTING, AND PARTICIPANTS: This was a record-linkage, retrospective, cohort study of patients who booked appointments at 2 FSCs between 2007 and 2018...
May 23, 2024: JAMA Neurology
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