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Scandinavian Journal of Urology

Mads Hvid Poulsen, Morten Frost, Bo Abrahamsen, Oke Gerke, Steen Walter, Lars Lund
OBJECTIVE: To analyze the prevalence of osteoporosis during androgen deprivation therapy (A.D.T.). BACKGROUND: Treatment and prognosis of prostate cancer necessitate management of long-term consequences of A.D.T., including accelerated bone loss resulting in osteoporosis; osteoporotic fractures are associated with excess morbidity and mortality. PATIENTS AND METHODS: Patients with prostate cancer awaiting initiation of A.D.T. were consecutively included from the daily clinic...
February 19, 2019: Scandinavian Journal of Urology
André Jacobsen, Ulla Nordström Joensen, Pernille Hammershøj Jensen
No abstract text is available yet for this article.
February 18, 2019: Scandinavian Journal of Urology
D M O Freitas, G L Andriole, R Castro-Santamaria, S J Freedland, D M Moreira
INTRODUCTION: To evaluate whether the presence of prostate atrophy (P.A.) in negative prostate biopsy is associated with prostate cancer (P.C.a) grade at surgical pathology among men who are ultimately diagnosed with P.C.a and undergo radical prostatectomy (R.P.). METHODS: A retrospective analysis was performed of 136 men from the placebo arm of the Reduction by Dutasteride of P.C.a Events (R.E.D.U.C.E.) trial who had a baseline prostate biopsy negative for P.C...
February 14, 2019: Scandinavian Journal of Urology
Carina Danemalm Jägervall, Jelmer Brüggemann, Ericka Johnson
BACKGROUND: The needs of gay men after prostate cancer treatment are becoming visible. This patient group reports a more negative impact of treatment than heterosexual men. Yet, gay men's experiences of post-treatment sexual changes are still little explored. This study aims to determine specific concerns of gay men's post-treatment sexual practices. METHODS: A qualitative study design was deployed using semi-structured interviews as data. Participants were purposefully sampled through advertisements and the snowball method...
February 7, 2019: Scandinavian Journal of Urology
Anna Wallerstedt Lantz, Johan Stranne, Stavros I Tyritzis, David Bock, David Wallin, Hanna Nilsson, Stefan Carlsson, Thordis Thorsteinsdottir, Ove Gustafsson, Jonas Hugosson, Anders Bjartell, Peter Wiklund, Gunnar Steineck, Eva Haglind
PURPOSE: All types of surgery are associated with complications. The debate is ongoing whether robot-assisted radical prostatectomy can lower this risk compared to open surgery. The objective of the present study was to evaluate post-operative adverse events leading to readmissions, using clinical records to classify these adverse events systematically. MATERIALS AND METHODS: A prospective controlled trial of men who underwent robot-assisted laparoscopic (RALP) or retropubic radical prostatectomy (RRP) at 14 departments of Urology (LAPPRO) between 2008 and 2011...
February 6, 2019: Scandinavian Journal of Urology
Sigurdur Gudjonsson
No abstract text is available yet for this article.
February 4, 2019: Scandinavian Journal of Urology
Frid Sofie Lichtwarck Bjugn, Elin Storjord, Roy Morten Kristensen, Ole-Lars Brekke
No abstract text is available yet for this article.
February 4, 2019: Scandinavian Journal of Urology
Frederik M Jacobsen, Mikkel Fode, Jens Sønksen, Dana A Ohl, Christian Fuglesang S Jensen
We present a case where microdissection testicular sperm extraction (m.T.E.S.E.) was used in a 36-year-old man after non-Hodgkin T-cell lymphoma treated with 2.5 years of chemotherapy, radiation therapy and autologous bone marrow transplantation (B.M.T.). During m.T.E.S.E. two areas of testis tissue with dilated seminiferous tubules were found both containing several sperm cells. These were cryopreserved and subsequently used for intracytoplasmic sperm injection, resulting in a pregnancy. Although the prognosis for sperm retrieval appears to be poor in most men who have undergone B...
January 30, 2019: Scandinavian Journal of Urology
Aino Siltari, Teemu J Murtola, Kirsi Talala, Kimmo Taari, Teuvo L J Tammela, Anssi Auvinen
BACKGROUND: The etiology of prostate cancer (PCa) involves environmental and genetic factors. Understanding the role of medication use on PCa risk may clarify the pathophysiological changes and mechanisms in development of cancer. METHODS: This study investigated PCa risk in relation to overall use of anti-hypertensive drugs and those with specific mechanisms of action. The study cohort (78,615 men) was linked to the prescription database to obtain information on medication use during 20-year follow-up...
January 30, 2019: Scandinavian Journal of Urology
Erik Sagen, Hans Hedelin, Olle Nelzén, Ralph Peeker
BACKGROUND: Transurethral resection of the prostate (TURP) is the reference standard surgical treatment for lower urinary tract symptoms (LUTS) related to benign prostatic enlargement. The aim of this study was to investigate the response rate following TURP in two distinctly different patient categories; men with bothersome LUTS and men in urinary retention (UR) requiring catheterisation. METHODS: In total, 355 men underwent TURP due to LUTS or UR. Responders in the LUTS group were defined as having an International Prostate Symptom Score ≤7 or >50% loss compared to baseline, a Qmax ≥ 15 mL/s or >50% gain compared to baseline, a post-void residual ≤100 mL or a bother score ≤2...
January 25, 2019: Scandinavian Journal of Urology
Sara V Tornberg, Harri Visapää, Tuomas P Kilpeläinen, Kimmo Taari, Riikka Järvinen, Kaisa Erkkilä, Harry Nisen, Petrus Järvinen
AIM: This study was conducted to evaluate the efficacy of surgical treatment for metastases accompanied by modern targeted therapies and to evaluate the performance of the Leuven-Udine (L.U.) prognostic groups model. METHODS: This retrospective analysis included 97 consecutive patients with metastatic renal cell carcinoma (mR.C.C.) who underwent surgery for metastases at Helsinki University Hospital between 2006 and 2017. The endpoints were overall survival (O.S...
January 20, 2019: Scandinavian Journal of Urology
Sophia Liff Maibom, Phillip Ryom, Katrine Schou-Jensen
A 40 year old woman had undergone surgery as a newborn due to a left sided congenital Bochdalek hernia with the ventricle, spleen, left kidney and adrenal gland located intrathoracically. After three pregnancies, she developed left sided flank pain and dyspnea. A CT scan showed a diaphragmatic hernia with a malrotated intrathoracic placed left kidney with minimal hydronephrosis. The spleen was located caudally in the left iliac fossa; there were no other abnormalities. The patient underwent a thoracotomy with a small resection of the diaphragm in order to replace the kidney in the abdominal cavity and closure of the diaphragmatic defect with a Gore-Tex patch...
January 17, 2019: Scandinavian Journal of Urology
M Skott, H Schrøder, J Hindkjaer, H J Kirkeby
BACKGROUND: This report presents a case where electroejaculation (EEJ) was used for semen cryopreservation (SCP), prior to gonadotoxic anti-cancer treatment in a 14-year old boy diagnosed with Hodgkins disease. METHOD: Two sessions of EEJ were performed with an interval of 48 hours. RESULTS: No complications were seen and the procedures resulted in nine frozen straws of motile spermatozoa. CONCLUSION: EEJ is a safe and feasible procedure for SCP in an adolescent cancer patient who is unable to masturbate or use penile vibratory stimulation (PVS)...
January 17, 2019: Scandinavian Journal of Urology
Per-Uno Malmström, Erik Skaaheim Haug, Peter J Boström, Sigidur Gudjónsson, Jørgen Bjerggaard Jensen
OBJECTIVE: To describe the management of patients with hematuria in the Nordic countries in relation to bladder cancer epidemiology, especially in the context of introducing fast track pathways with the aim of proposing a common guideline. MATERIALS AND METHODS: Epidemiological data on bladder cancer from each country, and the combined cancer registry, Nordcan, were analyzed. The evolution of the different national recommendations and the introduction of fast track pathways were assessed...
January 14, 2019: Scandinavian Journal of Urology
Takehisa Onishi, Sho Sekito, Takuji Shibahara, Katsunori Uchida, Takeshi Sasaki
OBJECTIVE: To compare the efficacy and safety of continuous saline bladder irrigation (CSBI) to a single immediate instillation of chemotherapy after transurethral resection of bladder tumor (TURBT) in patients with high grade primary non-muscle invasive bladder cancer (HG-NMIBC). MATERIALS AND METHODS: This study retrospectively reviewed 250 patients with primary NMIBC who were enrolled in a prospective randomized trial of CSBI vs single instillation of mitomycin C (SI-MMC) immediately after TURBT...
January 10, 2019: Scandinavian Journal of Urology
Erik Skaaheim Haug
No abstract text is available yet for this article.
January 10, 2019: Scandinavian Journal of Urology
Lucas Regis, Ana Celma, Jacques Planas, Ricardo Lopez, Sarai Roche, David Lorente, Jose Placer, Enrique Trilla, Juan Morote
PURPOSE: It remains unclear whether patients with prostate cancer suspicion and negative magnetic resonance imaging (M.R.I.) can safely obviate biopsy. The purpose of this study was to assess the clinical negative predictive value (N.P.V.) of M.R.I. in excluding prostate cancer. The secondary end-point was to compare N.P.V. to detect significant prostate cancer of M.R.I.The secondary end-point was to compare N.P.V. to detect significant prostate cancer in M.R.I. classified as P.I.-R.A...
January 10, 2019: Scandinavian Journal of Urology
Muhammad Elmussareh, Pia Carstensen Simonsen, Matthew Young, Pernille Skjold Kingo, Jakob Kristian Jakobsen, Jørgen Bjerggaard Jensen
OBJECTIVE: To evaluate the association between patients' organ-specific co-morbidities and post-operative complications following radical cystectomy for bladder cancer. PATIENTS AND METHODS: All patients who underwent radical cystectomy at Aarhus University Hospital during the period from January 2006 to February 2014 were included retrospectively. A total of 40 comorbidities and 59 complications were registered meticulously. Univariate and multivariate analyses were used to detect associations between the individual comorbidities and specific post-operative complications...
January 9, 2019: Scandinavian Journal of Urology
E David Crawford, B Tombal, T Keane, F Boccardo, K Miller, N Shore, J W Moul, J-E Damber, L Collette, B-E Persson
BACKGROUND: Gonadotropin releasing hormone (GnRH) antagonists suppress follicle-stimulating hormone (FSH) to lower levels than GnRH agonists. This may partially explain the differences between these agents on prostate cancer outcomes. In this post-hoc analysis, FSH and prostate specific antigen (PSA) responses and the impact of cross-over from leuprolide to degarelix were evaluated from a 1-year comparative study (CS21) and its extension study (CS21A). MATERIALS AND METHODS: Overall, 610 patients were enrolled in CS21, wherein PSA and FSH levels were evaluated monthly...
January 9, 2019: Scandinavian Journal of Urology
Simon Jønck, John Thomas Helgstrand, Martin Andreas Røder, Nina Klemann, Birgitte Grønkaer Toft, Klaus Brasso
BACKGROUND: To determine the prevalence and prognostic impact of incidental prostate cancer in patients undergoing radical cystoprostatectomy. METHODS: A nationwide population-based study of incidental prostate cancer diagnosed following radical cystoprostatectomy. Information on vital status, Gleason score, positive and negative tumor margins, pT-category and subsequent prostate cancer therapies were obtained from the Danish Prostate Cancer Registry and by manual chart review...
January 9, 2019: Scandinavian Journal of Urology
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