journal
https://read.qxmd.com/read/38808324/compliance-and-lifestyle-of-children-with-celiac-disease-in-the-iranian-children
#1
JOURNAL ARTICLE
Mandana Rafeey, Robabeh Ghergherehchi, Zeinab Nikniaz, Maryam Shoaran, Amaneh Hosseinalizadeh
BACKGROUND: Celiac disease is popular and needs a proper and constant gluten-free diet. However, data on the experience of the disease by children are insufficient. A few children have difficulty adjusting their lifestyles, and gluten-free foods are difficult for them. The present study aimed to find influential factors in the growth disorders and nonresponse to the treatment diet in celiac patients. MATERIALS AND METHODS: We gave a list of all children with celiac disease to the project manager and according to the criteria extracted additional information from their files...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38808323/effect-of-silybum-marianum-on-reduction-of-chemotherapy-induced-peripheral-neurotoxicity-with-cisplatin
#2
JOURNAL ARTICLE
Ali Haji Gholami, Hourieh Ansari, Adeleh Dadkhah
BACKGROUND: Chemotherapy-induced peripheral neurotoxicity (CIPN) is one of the major complications of chemotherapy regimens commonly used in the treatment of solid and hematologic cancers. Given the high incidence of CIPN in antitumor therapies in patients and limited studies on antioxidants, this study was aimed to investigate the effect of Silybum marianum (SM) on cisplatin-induced peripheral neuropathy. MATERIALS AND METHODS: This double-blind randomized clinical trial study was performed on 60 cancer patients treated with cisplatin chemotherapy at Seyyed-o-Shohada Hospital of Isfahan during 2019-2020...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38808322/cytotoxic-sulfoquinovosyl-glycerols-from-the-seaweed-sargassum-angustifolium-from-persian-gulf
#3
JOURNAL ARTICLE
Seyed Ebrahim Sajjadi, Sahar Ghobeishavi, Afsaneh Yegdaneh
BACKGROUNDS: Seaweeds are an important source of marine organisms that produce a lot of bioactive compounds. MATERIALS AND METHODS: In this research, the seaweed Sargassum angustifolium was collected from Bushehr province of Persian Gulf of Iran. The seaweed was extracted by methanol:ethyl acetate (1:1) using maceration method. The compounds were isolated with different column chromatography and HPLC(High Performance Liquid Chromatography) by silica gel and hexane:ethyl acetate as mobile phase...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38808321/diagnostic-value-of-dermoscopic-structures-in-predicting-superficial-basal-cell-carcinoma-in-the-skin-of-color
#4
JOURNAL ARTICLE
Maryam Khalili, Sare Mirahmadi, Simin Shamsimeymandi, Shahriar Dabiri, Rezvan Amiri, Mohammad Rezaei Zadeh Rukerd, Mahin Aflatoonian
BACKGROUND: Basal cell carcinoma (BCC) manifests different dermoscopic patterns in individuals with dark skin complexion compared to those with fair skin types. This study aimed to investigate the diagnostic utility of dermoscopy in discerning superficial BCC from other types of BCC, specifically in patients with dark skin complexion. MATERIALS AND METHODS: This cross-sectional study focuses on patients diagnosed with BCC who were referred for skin biopsy between July 2020 and September 2022...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38808320/evaluation-of-ip3r3-gene-silencing-effect-on-pyruvate-dehydrogenase-pdh-enzyme-activity-in-breast-cancer-cells-with-and-without-estrogen-receptor
#5
JOURNAL ARTICLE
Golnaz Vaseghi, Laleh Shariati, Majed Bahri Najafi, Zahra Malakootikhah, Hajar Naji Esfahani, Shaghayegh Haghjooy Javanmard
BACKGROUND: Inositol 1,4,5-trisphosphate receptor (IP3R), a critical calcium ion (Ca2+) regulator, plays a vital role in breast cancer (BC) metabolism. Dysregulated IP3R in BC cells can drive abnormal growth or cell death. Estradiol increases IP3R type 3 (IP3R3) levels in BC, promoting cell proliferation and metabolic changes, including enhanced pyruvate dehydrogenase (PDH) activity, which, when reduced, leads to cell apoptosis. The study silenced IP3R3 to assess its impact on PDH. MATERIALS AND METHODS: The study used IP3R3 small interfering RNA (siRNA) to target Michigan Cancer Foundation-7 (MCF-7) and MDA-MB-231 cell lines...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38525405/ovarian-yolk-sac-tumors-is-fertility-preservation-possible
#6
Fariba Behnamfar, Maryam Nazemi, Behnoosh Mohamadi
Yolk sac tumors make up 14% to 20% of all malignant ovarian germ cell tumors. Serum alpha-fetoprotein (AFP) levels are elevated in a significant number of patients and are useful for monitoring the response to treatment and for post-treatment surveillance. Surgery is required for diagnosis, staging, and treatment. The first case is a 12-year-old girl presented with abdominal pain. The ultrasonography (US) showed a huge pelvic tumor. AFP level was high (1000 mg/ml). Right salpingo-oophorectomy and pelvic lymphadenectomy were done...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38525404/toll-like-receptor-4-2-and-interleukin-1-receptor-associated-kinase4-possible-diagnostic-biomarkers-in-myelodysplastic-syndrome-patients
#7
JOURNAL ARTICLE
Parvin Khalilian, Nahid Eskandari, Mohammad Jafar Sharifi, Mohammad Soltani, Pardis Nematollahi
BACKGROUND: Myelodysplastic syndrome (MDS) is a clonal hematologic disorder that requires the integration of morphologic, cytogenetic, hematologic, and clinical findings for a successful diagnosis. Trying to find ancillary tests such as biomarkers improve the diagnosis process. Several studies showed that a disordered immune system is associated with MDS. The chronic activated innate immune system, particularly the Toll-like receptors (TLRs) pathway could be involved in the induction of the inflammation...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38525403/a-rare-case-of-klippel-trenaunay-syndrome-with-von-willebrand-factor-deficiency-and-multiple-accessory-spleens-a-case-report-and-brief-literature-review
#8
Vahid Falahati, Mahsa Fallahi, Mona Shahriarpour, Ali Ghasemi, Kazem Ghaffari
Klippel Trenaunay Syndrome (KTS) is an uncommon inherited syndrome identified by venous varicosities and capillary abnormalities. von Willebrand Disease is the most common inherited hemorrhage disturbance in humans, leading to insufficiency in von Willebrand Factor, which is a complex multimeric protein with two functions: it forms a bridge between the platelets and injured vascular areas and it attaches factor VIII and stabilizes it. We present a 13-year-old son with a typical clinical manifestation of KTS, including "port-wine stains" as capillary malformation, venous malformation, and hypertrophy of the left lower extremity, who also suffers from von Willebrand Disease type 3...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38525402/comparison-of-misoprostol-with-foley-catheter-vs-misoprostol-alone-for-cervical-ripening-and-induction-of-labor-in-patients-with-premature-rupture-of-membrane-a-randomized-clinical-trial-study
#9
JOURNAL ARTICLE
Seyyedeh Azam PoorHosseini, Masoumeh Mirteimouri, Maliheh RakhshaniFar, Seyede Houra Mousavi Vahed, Fedyeh Haghollahi
BACKGROUND: This study evaluates the effect of misoprostol alone in comparison with misoprostol with Foley catheter in preparing the cervix for induction of labor in women with premature rupture of the amniotic sac. MATERIALS AND METHODS: This randomized clinical trial study was performed from 2017 to 2019 on 206 pregnant women with singleton pregnancy and gestational age more than 36 weeks, whose rupture of the amniotic sac had occurred less than 12 hours and had a Bishop score less than 4...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38525401/effect-of-combined-application-of-hydrofluoric-and-phosphoric-acids-and-active-irrigation-with-a-microbrush-on-shear-bond-strength-of-lithium-disilicate-ceramics-to-enamel
#10
JOURNAL ARTICLE
Masoud Hatami, Farhood Massoumi, Mohammad Sadegh Safarian
BACKGROUND: This study assessed the effect of combined application of hydrofluoric (HF) acid and phosphoric acid (PA) and active irrigation (AI) with a microbrush on shear bond strength (SBS) of lithium disilicate (LDS) ceramics to enamel. MATERIALS AND METHODS: This in vitro study was conducted on 40 extracted teeth that received enamel preparation with a #12 cylindrical bur. Forty IPS e.max LT rods (3mm diameter, 6mm height) were fabricated and randomly assigned to four groups (n = 10) for surface treatment with 5% HF (group 1), 5% HF and AI with a microbrush for 20 seconds (group 2), 5% HF and 32% PA (group 3), and 5% HF and 32% PA plus AI with a microbrush for 20 seconds (group 4)...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38525400/co-occurrence-analysis-of-covid-19-publications-with-an-emphasis-on-the-global-health-governance-ghg
#11
JOURNAL ARTICLE
Leili Allahbakhshian Farsani, Nosrat Riahinia, Farshid Danesh, Ali Azimi
BACKGROUND: Analyzing co-occurrence is an effective way to monitor the overview of topic spreading. The present study aimed to conduct a co-occurrence analysis of scientific publications related to COVID-19, emphasizing Global Health Governance (GHG). MATERIALS AND METHODS: This applied research with an analytical approach was carried out on all the scientific publications related to COVID-19, emphasizing GHG (51056 records), extracted from PubMed Central on 26/01/2022...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38525399/quality-of-life-in-patients-with-phenylketonuria-a-systematic-review
#12
REVIEW
Zahra Jahangiri, Noushin Rostampour, Silva Hovsepian, Rojin Chegini, Mahin Hashemipour
The impact of phenylketonuria (PKU) on Quality of life (QoL) has been a topic of interest in recent research. This article reviews current researches on the impact of PKU on QoL. The review examines factors that may influence QoL, such as age, metabolic control, and treatment adherence. In this systematic review study, relevant articles were identified using a search strategy built with the keywords phenylketonuria, PKU, or hyperphenylalaninemia (or their synonyms) and QoL in Web of Science, Scopus, and PubMed databases...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38525398/the-application-of-artificial-intelligence-and-drug-repositioning-for-the-identification-of-fibroblast-growth-factor-receptor-inhibitors-a-review
#13
REVIEW
Parvin Zarei, Fahimeh Ghasemi
Artificial intelligence talks about modeling intelligent behavior through a computer with the least human involvement. Drug repositioning techniques based on artificial intelligence accelerate the research process and decrease the cost of experimental studies. Dysregulation of fibroblast growth factor (FGF) receptors as the tyrosine kinase family of receptors plays a vital role in a wide range of malignancies. Because of their functional significance, they were considered promising drug targets for the therapy of various cancers...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38525397/the-effect-of-dextrose-hypotonic-vs-saline-hydration-on-methotrexate-induced-nephrotoxicity-in-male-and-female-rats
#14
JOURNAL ARTICLE
Zahra Hasanpour, Samira Choopani, Farzaneh Ashrafi, Ardeshir Talebi, Mehdi Nematbaksh
BACKGROUND: High-dose methotrexate (HDMTX) as a cytotoxic agent might cause various side effects. Hyperhydration has been implemented as the major strategy to decrease the potential risk of toxicities induced by HDMTX. This study aims to assess the renoprotective effect of hydration with dextrose water (DW) 5% versus normal saline (N/S) 0.9% against methotrexate (MTX) induced nephrotoxicity. MATERIALS AND METHODS: This experimental animal study has been conducted on 36 Wistar rats (200-250 g) categorized into six groups, including male ( n = 6) and female ( n = 6) rats receiving sodium chloride 0...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38525396/therapeutic-effects-of-tretinoin-and-caffeine-treated-bone-marrow-derived-mesenchymal-stem-cell-on-immunological-features-of-ulcerative-colitis-an-animal-model-study
#15
JOURNAL ARTICLE
Behnaz Movaffaghbani, Hadi Esmaeili Gouvarchinghaleh, Mahdieh Farzanehpour, Jalal Shayegh
BACKGROUND: Ulcerative colitis (UC) is one of the inflammatory gastrointestinal diseases. It causes irritation, inflammation, and ulcers in the digestive tract. UC is distinguished clinically by abdominal and rectal pain and intestinal secretion abnormalities. Mesenchymal stem cell (MSC) therapy could be the underlying treatment for UC. This study aimed to compare the results of MSC therapy with tretinoin and caffeine in an animal model. MATERIALS AND METHODS: Sixty male BALB/c mice were randomly divided into six equal groups...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38525395/the-effect-of-rivaroxaban-in-the-complementary-therapy-of-sudden-sensorineural-hearing-loss
#16
JOURNAL ARTICLE
Mehrdad Rogha, Ehsan Moshtaghi
BACKGROUND: Due to the importance of sudden sensorineural hearing loss (SSNHL) and the possible role of blood coagulation in its mechanism and the likely therapeutic effect of anticoagulants and also the lack of studies in this field, this study aimed to evaluate the effect of rivaroxaban (RXA) in the treatment of this disease. MATERIALS AND METHODS: The present double-blind randomized clinical trial study was performed on 34 patients with SSNHL. Patients were randomly divided into two groups...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38525394/the-effectiveness-of-neurodynamic-techniques-in-patients-with-diabetic-peripheral-neuropathy-study-protocol-for-a-randomized-sham-controlled-trial
#17
JOURNAL ARTICLE
Mahdi Ashoori, Mohammadreza Pourahmadi, Seyed Ebrahim Hashemi, Mehdi Dadgoo, Mahboobeh Sadat Hosseini
BACKGROUND: Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes mellitus (DM). DPN is the primary risk factor for diabetic foot ulcers that can cause amputation. Although several observational studies have investigated the morphological and biomechanical characteristics of peripheral nerves in DPN, interventional studies regarding the effectiveness of neurodynamic techniques (NDT) in DPN patients are confined to a handful. The effects of NDT on neuropathy severity, nerve conduction parameters, quality of life (QoL), and mechanosensitivity have not been explored yet in this population...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38525393/comparative-evaluation-of-direct-laryngoscopy-versus-glidescope-for-the-purpose-of-laryngoscopy-management-and-intubation-in-candidates-of-cesarean-delivery-with-general-anesthesia
#18
JOURNAL ARTICLE
Azim Honarmand, Mahtab Ebrahim Babaei, Mohammad Jafari, Mohammad Reza Safavi
BACKGROUND: The present study aimed at comparing the hemodynamic responses to laryngoscopy and initiation of intubation with either direct or video-assisted laryngoscopy. MATERIALS AND METHODS: This double-blind clinical trial was performed on 90 pregnant women candidates for cesarean section under general anesthesia. The participants were divided into two groups. In the first group, intubation was performed using direct Macintosh laryngoscope (MCL group). The second group underwent intubation using the GlideScope video laryngoscope (GSL group)...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38525392/the-efficacy-of-repetitive-transcranial-magnetic-stimulation-rtms-versus-transcranial-direct-current-stimulation-tdcs-on-migraine-headaches-a-randomized-clinical-trial
#19
JOURNAL ARTICLE
Fatemeh Naji, Mohammad Reza Sharbafchi, Fariborz Khorvash, Mohammad R Maracy, Niloofar Ghasemi Mobarak Abadi
BACKGROUND: Non-pharmacologic prophylactic methods for chronic migraine have been developed, including the promising non-invasive techniques of repetitive transcranial magnetic stimulation (rTMS) and transcranial direct-current stimulation (tDCS). This study aimed to compare the efficacy of rTMS and tDCS on pain intensity, the impact of headaches on daily life, anxiety, and depression in migraine headaches patients. MATERIALS AND METHODS: This randomized clinical trial was conducted on 72 patients with migraine headaches, randomly allocated to the rTMS and tDCS groups...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38525391/a-randomized-comparative-study-of-the-use-of-individual-modality-and-combination-of-endoscopic-retrograde-cholangiopancreatography-ercp-and-digital-single-operator-cholangioscopy-dsoc-for-diagnosis-of-indeterminate-biliary-strictures
#20
JOURNAL ARTICLE
Dheeraj Kumar, Vishwa M Dayal, Sanjeev K Jha, Ashish K Jha, Ravi K Kumar
BACKGROUND: To determine the superiority of the combination of endoscopic retrograde cholangiopancreatography (ERCP) and digital single-operator cholangioscopy (DSOC) in the same sitting over the individual modality alone in patients with indeterminate biliary strictures. MATERIALS AND METHODS: A randomized study enrolled 60 adult patients with biliary strictures who were randomized into two groups: ERCP + DSOC and ERCP/DSOC. Histopathologic or cytologic assessment was performed in terms of benign, indeterminate, or malignant nature of the strictures...
2024: Advanced Biomedical Research
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