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Journals Frontiers in Cellular and Infe...

Frontiers in Cellular and Infection Microbiology

https://read.qxmd.com/read/38873099/detection-of-hanseniaspora-opuntiae-in-anovaginal-samples-of-pregnant-women-in-rio-de-janeiro-brazil-a-case-report
#1
JOURNAL ARTICLE
Tatiane Nobre Pinto, Laura M A Oliveira, Gisela L da Costa, Natália Silva Costa, Elaine Cristina Francisco, Tatiana C A Pinto, Manoel M E Oliveira
In this study, we report the first isolation of Hanseniaspora opuntiae obtained from four pregnant women in Brazil. Clinical isolates were obtained from four samples taken between 35 and 37 gestational weeks, as part of the routine antenatal care for maternal colonization screening for Streptococcus agalactiae group B. The patients were immunocompetent, with two of them diagnosed with gestational diabetes mellitus. Species identification was performed by MALDI-TOF MS and rDNA sequencing. While Hanseniaspora species have not traditionally been considered a typical opportunist pathogen, our findings emphasize the importance of investigating and screening for Hanseniaspora in pregnant populations, highlighting H...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38873098/editorial-molecular-mechanisms-of-resistance-to-last-resort-antimicrobials-in-enterobacterales
#2
EDITORIAL
John Osei Sekyere, Thamarai Schneiders, Piotr Majewski
No abstract text is available yet for this article.
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38873097/influences-of-bacterial-extracellular-vesicles-on-macrophage-immune-functions
#3
REVIEW
Bowei Jiang, Junyun Huang
Bacterial extracellular vesicles (EVs) are crucial mediators of information transfer between bacteria and host cells. Macrophages, as key effector cells in the innate immune system, have garnered widespread attention for their interactions with bacterial EVs. Increasing evidence indicates that bacterial EVs can be internalized by macrophages through multiple pathways, thereby influencing their immune functions. These functions include inflammatory responses, antimicrobial activity, antigen presentation, and programmed cell death...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38873096/a-novel-diagnostic-approach-to-paratuberculosis-in-dairy-cattle-using-near-infrared-spectroscopy-and-aquaphotomics
#4
JOURNAL ARTICLE
Saba Behdad, Abbas Pakdel, Reza Massudi
INTRODUCTION: As a contagious and chronic disease in the livestock industry, Paratuberculosis is a significant threat to dairy herds' genetic and economic resources. Due to intensive breeding and high production of dairy cattle, the incidence and prevalence are higher. Developing non-destructive diagnostic methods for the early detection and identification of healthy animals is paramount for breeding programs. Conventional methods are almost entirely destructive, have low accuracy, lack precision, and are time-consuming...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38873095/a-rare-case-of-successful-treatment-of-peritoneal-dialysis-patient-with-serratia-marcescens-peritonitis-without-catheter-removal-case-report-and-literature-review
#5
REVIEW
Ruizhi Xie, Ying Ling, Yaru Huang, Lulu Qin, Kun Bao, Xindong Qin
Serratia marcescens, as a Gram-negative opportunistic pathogen, is a rare cause of peritonitis and has worse clinical outcomes than Gram-positive peritonitis. In this case report, we describe a case of Serratia marcescens associated peritonitis that was successfully cured without catheter removal. A 40-year-old male patient with peritoneal dialysis who worked in the catering industry was admitted to the hospital for 16 hours after the discovery of cloudy peritoneal dialysate and abdominal pain. Ceftazidime and cefazolin sodium were immediately given intravenously as an empirical antibiotic regimen...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38868299/relationship-between-gut-microbiota-and-the-pathogenesis-of-gestational-diabetes-mellitus-a-systematic-review
#6
JOURNAL ARTICLE
Sheng Ma, Yuping Wang, Xiaoxia Ji, Sunjuan Dong, Shengnan Wang, Shuo Zhang, Feiying Deng, Jingxian Chen, Benwei Lin, Barkat Ali Khan, Weiting Liu, Kaijian Hou
INTRODUCTION: Gestational diabetes mellitus (GDM) is a form of gestational diabetes mellitus characterized by insulin resistance and abnormal function of pancreatic beta cells. In recent years, genomic association studies have revealed risk and susceptibility genes associated with genetic susceptibility to GDM. However, genetic predisposition cannot explain the rising global incidence of GDM, which may be related to the increased influence of environmental factors, especially the gut microbiome...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38868298/manuka-honey-as-a-non-antibiotic-alternative-against-staphylococcus-spp-and-their-small-colony-variant-scvs-phenotypes
#7
REVIEW
Laura A Onyango, Jiawei Liang
The antibiotic resistance (ABR) crisis is an urgent global health priority. Staphylococci are among the problematic bacteria contributing to this emergency owing to their recalcitrance to many clinically important antibiotics. Staphylococcal pathogenesis is further complicated by the presence of small colony variants (SCVs), a bacterial subpopulation displaying atypical characteristics including retarded growth, prolific biofilm formation, heightened antibiotic tolerance, and enhanced intracellular persistence...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38863834/progress-of-research-and-application-of-heyndrickxia-coagulans-bacillus-coagulans-as-probiotic-bacteria
#8
REVIEW
Jie Liang, Chunhai Li, Zouquan Chen, Fangyu Guo, Jiaxin Dou, Ting Wang, Zhen Shang Xu
Probiotics are defined as living or dead bacteria and their byproducts that maintain the balance of the intestinal microbiome. They are non-toxic, non-pathogenic, and do not release any toxins either within or outside the body. Adequate consumption of probiotics can enhance metabolite production, increase immunity, maintain a balanced intestinal flora, and stimulate growth. Probiotics do not have negative antibiotic effects and help maintain the natural flora in animals in a balanced state or prevent dysbacteriosis...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38863833/exploring-monkeypox-virus-proteins-and-rapid-detection-techniques
#9
REVIEW
Kamila Sagdat, Assel Batyrkhan, Damira Kanayeva
Monkeypox (mpox) is an infectious disease caused by the mpox virus and can potentially lead to fatal outcomes. It resembles infections caused by viruses from other families, challenging identification. The pathogenesis, transmission, and clinical manifestations of mpox and other Orthopoxvirus species are similar due to their closely related genetic material. This review provides a comprehensive discussion of the roles of various proteins, including extracellular enveloped virus (EEV), intracellular mature virus (IMV), and profilin-like proteins of mpox...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38863832/oral-microbiome-sequencing-revealed-the-enrichment-of-fusobacterium-sp-porphyromonas-sp-campylobacter-sp-and-neisseria-sp-on-the-oral-malignant-fibroma-surface-of-giant-panda
#10
JOURNAL ARTICLE
Xiaowan Wang, Meiling Jing, Qizhao Ma, Yongwang Lin, Ting Zheng, Jiangchuan Yan, Libing Yun, Chengdong Wang, Yuqing Li
INTRODUCTION: Microbial community composition is closely associated with host disease onset and progression, underscoring the importance of understanding host-microbiota dynamics in various health contexts. METHODS: In this study, we utilized full-length 16S rRNA gene sequencing to conduct species-level identification of the microorganisms in the oral cavity of a giant panda ( Ailuropoda melanoleuca ) with oral malignant fibroma. RESULTS: We observed a significant difference between the microbial community of the tumor side and non-tumor side of the oral cavity of the giant panda, with the latter exhibiting higher microbial diversity...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38863831/novel-anti-acanthamoeba-effects-elicited-by-a-repurposed-poly-adp-ribose-polymerase-inhibitor-az9482
#11
JOURNAL ARTICLE
Lijun Chen, Wei Han, Wenwen Jing, Meng Feng, Qingtong Zhou, Xunjia Cheng
INTRODUCTION: Acanthamoeba infection is a serious public health concern, necessitating the development of effective and safe anti-Acanthamoeba chemotherapies. Poly (ADP-ribose) polymerases (PARPs) govern a colossal amount of biological processes, such as DNA damage repair, protein degradation and apoptosis. Multiple PARP-targeted compounds have been approved for cancer treatment. However, repurposing of PARP inhibitors to treat Acanthamoeba is poorly understood. METHODS: In the present study, we attempted to fill these knowledge gaps by performing anti-Acanthamoeba efficacy assays, cell biology experiments, bioinformatics, and transcriptomic analyses...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38863830/metagenomic-next-generation-sequencing-assisted-diagnosis-of-a-rare-case-of-primary-cutaneous-acanthamoebiasis-in-an-hiv-patient-a-case-report
#12
JOURNAL ARTICLE
Wei Fan, Pin Li, Qihao Wei, Xinru Liu, Yuxiang Cai, Bin Li, Yaping Lu
Pathogenic and free-living Acanthamoeba are widely distributed in the environment and have been reported to cause keratitis and universally fatal encephalitis. Primary cutaneous acanthamoebiasis caused by Acanthamoeba is exceedingly rare and presents as isolated necrotic cutaneous lesions without involvement of the cornea or central nervous system. Cutaneous acanthamoebiasis often occurs in immunocompromised patients and is likely overlooked or even misdiagnosed only by cutaneous biopsy tissue histopathological analysis...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38863829/covid-19-influenced-gut-dysbiosis-post-acute-sequelae-immune-regulation-and-therapeutic-regimens
#13
REVIEW
Sterlin T Raj, Alexander W Bruce, Muralidharan Anbalagan, Hemalatha Srinivasan, Sasikala Chinnappan, Mogana Rajagopal, Kushagra Khanna, Harish C Chandramoorthy, Ravishankar Ram Mani
The novel coronavirus disease 2019 (COVID-19) pandemic outbreak caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has garnered unprecedented global attention. It caused over 2.47 million deaths through various syndromes such as acute respiratory distress, hypercoagulability, and multiple organ failure. The viral invasion proceeds through the ACE2 receptor, expressed in multiple cell types, and in some patients caused serious damage to tissues, organs, immune cells, and the microbes that colonize the gastrointestinal tract (GIT)...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38860121/editorial-reviews-in-microbiome-in-health-disease
#14
EDITORIAL
Suhana Chattopadhyay, Leena Malayil
No abstract text is available yet for this article.
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38854658/orphan-response-regulator-nnar-is-critical-for-nitrate-and-nitrite-assimilation-in-mycobacterium-abscessus
#15
JOURNAL ARTICLE
Breven S Simcox, Kyle H Rohde
Mycobacterium abscessus ( Mab ) is an opportunistic pathogen afflicting individuals with underlying lung disease such as Cystic Fibrosis (CF) or immunodeficiencies. Current treatment strategies for Mab infections are limited by its inherent antibiotic resistance and limited drug access to Mab in its in vivo niches resulting in poor cure rates of 30-50%. Mab's ability to survive within macrophages, granulomas and the mucus laden airways of the CF lung requires adaptation via transcriptional remodeling to counteract stresses like hypoxia, increased levels of nitrate, nitrite, and reactive nitrogen intermediates...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38846355/antifungal-potential-of-multi-drug-resistant-pseudomonas-aeruginosa-harnessing-pyocyanin-for-candida-growth-inhibition
#16
JOURNAL ARTICLE
Mohammad Oves, Mohd Shahnawaz Khan, Majed Al-Shaeri, Mohammad Saghir Khan
INTRODUCTION: Pseudomonas aeruginosa is notorious for its multidrug resistance and its involvement in hospital-acquired infections. In this study, 20 bacterial strains isolated from soil samples near the Hindan River in Ghaziabad, India, were investigated for their biochemical and morphological characteristics, with a focus on identifying strains with exceptional drug resistance and pyocyanin production. METHODS: The isolated bacterial strains were subjected to biochemical and morphological analyses to characterize their properties, with a particular emphasis on exopolysaccharide production...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38846354/host-factors-of-sars-cov-2-in-infection-pathogenesis-and-long-term-effects
#17
REVIEW
Yu Zhang, Shihan Chen, Yan Tian, Xianghui Fu
SARS-CoV-2 is the causative virus of the devastating COVID-19 pandemic that results in an unparalleled global health and economic crisis. Despite unprecedented scientific efforts and therapeutic interventions, the fight against COVID-19 continues as the rapid emergence of different SARS-CoV-2 variants of concern and the increasing challenge of long COVID-19, raising a vast demand to understand the pathomechanisms of COVID-19 and its long-term sequelae and develop therapeutic strategies beyond the virus per se ...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38846353/deciphering-the-microbial-landscape-of-lower-respiratory-tract-infections-insights-from-metagenomics-and-machine-learning
#18
JOURNAL ARTICLE
Jiahuan Li, Anying Xiong, Junyi Wang, Xue Wu, Lingling Bai, Lei Zhang, Xiang He, Guoping Li
BACKGROUND: Lower respiratory tract infections represent prevalent ailments. Nonetheless, current comprehension of the microbial ecosystems within the lower respiratory tract remains incomplete and necessitates further comprehensive assessment. Leveraging the advancements in metagenomic next-generation sequencing (mNGS) technology alongside the emergence of machine learning, it is now viable to compare the attributes of lower respiratory tract microbial communities among patients across diverse age groups, diseases, and infection types...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38846352/optimization-of-genetic-distance-threshold-for-inferring-the-crf01_ae-molecular-network-based-on-next-generation-sequencing
#19
JOURNAL ARTICLE
Lijuan Hu, Bin Zhao, Mingchen Liu, Yang Gao, Haibo Ding, Qinghai Hu, Minghui An, Hong Shang, Xiaoxu Han
INTRODUCTION: HIV molecular network based on genetic distance (GD) has been extensively utilized. However, the GD threshold for the non-B subtype differs from that of subtype B. This study aimed to optimize the GD threshold for inferring the CRF01_AE molecular network. METHODS: Next-generation sequencing data of partial CRF01_AE pol sequences were obtained for 59 samples from 12 transmission pairs enrolled from a high-risk cohort during 2009 and 2014. The paired GD was calculated using the Tamura-Nei 93 model to infer a GD threshold range for HIV molecular networks...
2024: Frontiers in Cellular and Infection Microbiology
https://read.qxmd.com/read/38846351/molecular-characterization-of-sars-cov-2-nucleocapsid-protein
#20
REVIEW
Yanping Huang, Junkai Chen, Siwei Chen, Congcong Huang, Bei Li, Jian Li, Zhixiong Jin, Qiwei Zhang, Pan Pan, Weixing Du, Long Liu, Zhixin Liu
Corona Virus Disease 2019 (COVID-19) is a highly prevalent and potent infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Until now, the world is still endeavoring to develop new ways to diagnose and treat COVID-19. At present, the clinical prevention and treatment of COVID-19 mainly targets the spike protein on the surface of SRAS-CoV-2. However, with the continuous emergence of SARS-CoV-2 Variants of concern (VOC), targeting the spike protein therapy shows a high degree of limitation...
2024: Frontiers in Cellular and Infection Microbiology
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