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Taiwan Journal of Ophthalmology

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https://read.qxmd.com/read/30637197/short-term-postoperative-perfluoro-n-octane-tamponade-for-pediatric-recurrent-retinal-detachment
#1
Kiet-Phang Ling, An-Lun Wu, Chi-Chun Lai, Wei-Chi Wu
We report a case with multiple recurrences of retinal detachment (RD) with severe proliferative vitreoretinopathy in a 12-year-old child who underwent vitrectomy using a heavy liquid perfluoro-n-octane (PFO) as a short-term postoperative tamponade. He had an encircling band and three vitrectomies with gas, followed by silicone oil tamponade for retinal redetachment prior to the use of PFO as a short-term tamponade. Short-term PFO tamponade was used in which inferior retinal reattachment was considered to be difficult with conventional gas or silicone oil tamponade, especially in regard to proper postoperative posturing...
October 2018: Taiwan Journal of Ophthalmology
https://read.qxmd.com/read/30637196/bevacizumab-or-laser-for-aggressive-posterior-retinopathy-of-prematurity
#2
Michael Blair, Jose Maria Garcia Gonzalez, Laura Snyder, Sidney Schechet, Mark Greenwald, Michael Shapiro, Sarah Hilkert Rodriguez
PURPOSE: The purpose of this study was to report the rate of reactivation and structural outcome, after the laser or bevacizumab treatment for aggressive posterior retinopathy of prematurity (APROP). METHODS: Retrospective chart review was conducted on consecutive infants with APROP treated with (1) laser or (2) bevacizumab, followed by fluorescein angiography and prophylactic laser to the persistent avascular retina. RESULTS: Thirty-six eyes of 19 patients were included in this study...
October 2018: Taiwan Journal of Ophthalmology
https://read.qxmd.com/read/30637195/special-considerations-for-pediatric-vitreoretinal-surgery
#3
REVIEW
Nicola Y Gan, Wai-Ching Lam
In this review, the authors present special considerations a vitreoretinal surgeon should take into account before embarking on surgery in a pediatric eye. First, the anatomy of a pediatric eye is different from an adult and changes as the child grows. This is important especially in relation to the placement of transconjunctival ports. The structural characteristics of the sclera are also different, with lower scleral rigidity found in pediatric eyes. When considering vitrectomy, a posterior pars plicata lens-sparing technique should be considered...
October 2018: Taiwan Journal of Ophthalmology
https://read.qxmd.com/read/30637194/retinal-detachments-in-the-pediatric-population
#4
REVIEW
Nicola Yi'an Gan, Wai-Ching Lam
In this review, we present a concise summary of the more commonly seen types of retinal detachments (RDs) that one can encounter in pediatric patients. A spectrum of diseases from rhegmatogenous RD in Stickler syndrome, Marfan syndrome, and choroidal coloboma to exudative RD in Coats disease, to tractional RD in persistent fetal vasculature, and combined RDs in familial exudative vitreoretinopathy are described with the management pearls for each.
October 2018: Taiwan Journal of Ophthalmology
https://read.qxmd.com/read/30637193/current-concepts-and-techniques-of-vitrectomy-for-retinopathy-of-prematurity
#5
REVIEW
Shunji Kusaka
Retinopathy of prematurity (ROP) is a leading cause of childhood blindness worldwide. ROP screening and interventions (e.g., laser ablation and anti-vascular endothelial growth factor [VEGF] therapy) at the right time can reduce disease activity and prevent retinal detachment. However, sometimes, ROP is refractory to treatment, leading to tractional retinal detachment (TRD), requiring surgical intervention, such as vitrectomy. Vitrectomy for Stage 5 ROP (total retinal detachment) is beneficial in preventing total blindness in some patients...
October 2018: Taiwan Journal of Ophthalmology
https://read.qxmd.com/read/30637192/stage-5-retinopathy-of-prematurity-an-update
#6
REVIEW
Parveen Sen, Smriti Jain, Pramod Bhende
Retinopathy of prematurity (ROP) is one of the most common causes of preventable blindness in children. In spite of the availability of various treatment options, and favorable results with timely intervention, many infants present to the ophthalmologists in the advanced end stage of the disease due to lack of awareness especially in the developing nations. This blinding or Stage 5 of ROP presents with total retinal detachment and has to be managed surgically. The surgical techniques for Stage 5 ROP are unique and demanding...
October 2018: Taiwan Journal of Ophthalmology
https://read.qxmd.com/read/30637191/knudson-to-embryo-selection-a-story-of-the-genetics-of-retinoblastoma
#7
REVIEW
Vrushali Athavale, Vikas Khetan
Retinoblastoma, the most common primary intraocular malignancy of the young, is a prototype hereditary cancer. Due to its fairly predictable Mendelian inheritance, easily examinable tumors, and early age of presentation, RB has served as the most extensively studied model for genetics in cancer. The genetic strides in RB have progressed at an exponential rate since the 1970s. The highly morbid, reasonably curable and distinctly predictable inheritance pattern of RB; not to mention its propensity to affect our young, forms the basis of aggressively encouraging genetic diagnosis in all patients of RB...
October 2018: Taiwan Journal of Ophthalmology
https://read.qxmd.com/read/30637190/the-importance-of-early-diagnosis-of-stickler-syndrome-finding-opportunities-for-preventing-blindness
#8
REVIEW
Michael J Shapiro, Michael P Blair, Mark A Solinski, David L Zhang, Sayena Jabbehdari
Stickler Syndrome (SS) is a significant cause of retinal blindness in children. The immediate cause of blindness is retina detachment from giant retinal tear (GRT). It is frequently diagnosed late and the giant retinal tear (GRT) may be complicated by high-grade proliferative vitreoretinopathy (PVR). The surgery for the combined GRT with PVR has limited structural results and the vision mainly remains impaired. In order to improve the visual outcomes, we propose an organized program oriented toward early diagnosis and surveillance...
October 2018: Taiwan Journal of Ophthalmology
https://read.qxmd.com/read/30637189/foveal-hypoplasia-and-optical-coherence-tomographic-imaging
#9
REVIEW
Hiroyuki Kondo
Foveal hypoplasia is a retinal disorder in which there is a lack of full development of the morphology of the fovea. The optical coherence tomography (OCT) and functional findings are presented in relation to the underlying genetic and developmental conditions. Recent advancements of high-resolution OCT imaging have unveiled characteristics of foveal hypoplasia that were not detected by conventional imaging methods. An absence of a foveal pit does not necessarily imply poor visual acuity, and the maturation of the cone photoreceptors is important for the visual acuity...
October 2018: Taiwan Journal of Ophthalmology
https://read.qxmd.com/read/30637188/pediatric-retina-a-challenging-yet-fascinating-field
#10
EDITORIAL
Wei-Chi Wu
No abstract text is available yet for this article.
October 2018: Taiwan Journal of Ophthalmology
https://read.qxmd.com/read/30294533/acute-syphilitic-posterior-placoid-chorioretinopathy-mimicking-central-serous-chorioretinopathy-a-case-report
#11
Chu-Yen Huang, Eugene Yu-Chuan Kang, Kuan-Jen Chen, Nan-Kai Wang
A 51-year-old man had experienced declining visual acuity for 4 months. His best-corrected visual acuity was 20/40 in both eyes. Ophthalmoscopic examination showed a yellowish placoid lesion over the macular area, and spectral-domain optical coherence tomography (SD-OCT) revealed subretinal fluid accumulation in the left eye, which resembled that seen with central serous chorioretinopathy (CSCR). Three days later, fluorescein angiography (FA) revealed fluorescein leakage, and indocyanine green angiography (ICGA) showed hypofluorescence over the lesion...
July 2018: Taiwan Journal of Ophthalmology
https://read.qxmd.com/read/30294532/bilateral-anterior-uveitis-after-immunotherapy-for-malignant-melanoma
#12
Chia-Jui Chang, Shih-Jen Chen, De-Kuang Hwang, Catherine Jui-Ling Liu
Immune checkpoint blockade therapy is relatively a new treatment for cancer which has shown promising results. However, immune-related side effects including uveitis have occasionally been reported during this therapy. Herein, we report the case of a 65-year-old male who suffered bilateral anterior uveitis after immune checkpoint blockade therapy with pembrolizumab and ipilimumab for malignant melanoma. His symptoms and signs improved after topical treatment with corticosteroids. Clinicians should be aware that uveitis can be an immune-related adverse event of immunotherapy...
July 2018: Taiwan Journal of Ophthalmology
https://read.qxmd.com/read/30294531/interferon-%C3%AE-2a-treatment-for-refractory-beh%C3%A3-et-s-disease
#13
Yung Jen Lai, Wei-Chun Chan
We report a young male patient with Behçet's disease who suffered from sight-threatening recurrences under treatment with azathioprine, cyclosporine, and prednisolone. His uveitis responded well to antitumor necrosis factor (TNF)-alpha (adalimumab) for 5 months subsequently. Severe uveitis recurred soon after discontinuation of anti-TNF alpha therapy and could not be controlled well with reinstitution of the anti-TNF alpha therapy. Interferon- α 2a (IFN- α 2a) was then given along with low-dose oral prednisone (10 mg/day), and the uveitis responded well to this therapy...
July 2018: Taiwan Journal of Ophthalmology
https://read.qxmd.com/read/30294530/the-rescue-effect-of-adalimumab-in-the-treatment-of-refractory-pediatric-panuveitis-complicated-with-steroid-induced-glaucoma
#14
Wei-Ning Ku, Chun-Ju Lin, Yi-Yu Tsai
We report the rescue effects of adalimumab (HUMIRA® ) therapy in a case of refractory pediatric panuveitis complicated with steroid-induced glaucoma. A 13-year-old girl had suffered from blurred vision since January 2013. Bilateral idiopathic panuveitis with macular edema (ME) was diagnosed. She had previously been treated with systemic steroids, methotrexate, cyclosporine, and mycophenolate. All treatments had failed to suppress the ocular inflammation and ME persisted. Intravitreal dexamethasone implant injections were given to both eyes and ME subsided; however, complications with steroid-induced glaucoma and cataract occurred...
July 2018: Taiwan Journal of Ophthalmology
https://read.qxmd.com/read/30294529/ultra-widefield-angiography-in-the-diagnosis-and-management-of-uveitis
#15
Ning-Yi Hsia, You-Ling Li, Chun-Ju Lin, Henry Bair, Chun-Ting Lai, Jane-Ming Lin, Wen-Lu Chen, Peng-Tai Tien, Chung-Yuan Kuo, Yi-Yu Tsai
PURPOSE: The aim of this study is to evaluate the clinical use of ultra-widefield angiography (UWFA) in uveitis. MATERIALS AND METHODS: We showed the UWFA and traditional 55° fluorescein angiography (FA) of four cases with Eales' disease, idiopathic retinal vasculitis, aneurysms, and neuroretinitis syndrome, Behçet's disease, and idiopathic panuveitis in a tertiary medical center. Comparison of UWFA with traditional 55°FA in the diagnosis and management of uveitis and review of the literature is also presented...
July 2018: Taiwan Journal of Ophthalmology
https://read.qxmd.com/read/30294528/photorefractive-keratectomy-for-correcting-residual-refractive-error-following-cataract-surgery-with-premium-intraocular-lens-implantation
#16
Yuan-Yao Fan, Chi-Chin Sun, Hung-Chi Chen, David Hui-Kang Ma
PURPOSE: The aim of this study is to evaluate the effectiveness and predictability of photorefractive keratectomy (PRK) for correcting residual refractive error following cataract surgery with premium intraocular lens (IOL) implantation. METHODS: We conducted a retrospective review of the medical records of patients who received PRK for correcting residual hyperopia, myopia, and/or astigmatism due to unsatisfied uncorrected distance visual acuity (UDVA) after cataract extraction with implantation of aspheric, diffractive multifocal, or toric IOL from September 2011 to December 2017...
July 2018: Taiwan Journal of Ophthalmology
https://read.qxmd.com/read/30294527/dexamethasone-implant-0-7-mg-in-indian-patients-with-macular-edema-real-life-scenario
#17
Manish Nagpal, Navneet Mehrotra, Rakesh Juneja, Hardik Jain
Context: Role of Ozurdex in macular edema due to various posterior segment pathologies. AIM: The aim of this study is to report outcome of Ozurdex implant in macular edema (ME) secondary to various posterior segment pathologies. SETTINGS AND DESIGN: This was a single-center, retrospective, interventional study. SUBJECTS AND METHODS: Patients of ME were treated with one or more Ozurdex implants (0.7 mg). Data collection included demographic details, best-corrected visual acuity (BCVA), central foveal thickness (CFT), duration of efficacy, and record of adverse events (if any) within 24 weeks...
July 2018: Taiwan Journal of Ophthalmology
https://read.qxmd.com/read/30294526/correction-of-presbyopia-an-integrated-update-for-the-practical-surgeon
#18
REVIEW
Marie Joan Therese D Balgos, Veronica Vargas, Jorge L Alió
Presbyopia results from loss or insufficiency of the eye's accommodative ability, and clinically manifests as the inability to focus near objects on the retina. It is one of the most common causes of visual impairment worldwide especially in adults of productive or working age. Various means of compensating for the loss of accommodative ability have been devised from optical tools such as spectacles and contact lenses, to topical medications and to surgical procedures. A comprehensive search on journal articles about topical and surgical correction of presbyopia was undertaken...
July 2018: Taiwan Journal of Ophthalmology
https://read.qxmd.com/read/30294525/recommendation-of-using-systemic-anti-tumor-necrosis-factor-alpha-for-the-treatment-of-noninfectious-uveitis-in-taiwan
#19
REVIEW
De-Kuang Hwang, Yih-Shiou Hwang, Ming-Ling Tsai, Chun-Ju Lin, Wei-Chun Chan, Yo-Chen Chang, Der-Yuan Chen, Tsu-Yi Hsieh, Shwu-Jiuan Sheu, Chang-Ping Lin
Noninfectious uveitis is a sight-threatening disease with an autoimmune or autoinflammatory basis. Systemic treatment is required if intraocular inflammation threatens a patient's vision or cannot be controlled locally and when it is associated with systemic rheumatic diseases. Corticosteroids and immunomodulatory chemotherapy are the conventional initial treatments. However, the various side effects of these therapies increase the burden on patients, not only physically but also mentally. Moreover, uncontrolled inflammation and poor visual outcomes have sometimes been recorded despite the combination of these medications or their high dosage...
July 2018: Taiwan Journal of Ophthalmology
https://read.qxmd.com/read/30294524/biologics-for-the-treatment-of-noninfectious-uveitis
#20
EDITORIAL
Chang-Ping Lin
No abstract text is available yet for this article.
July 2018: Taiwan Journal of Ophthalmology
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