journal
Journals Translational Andrology and Ur...

Translational Andrology and Urology

https://read.qxmd.com/read/38590969/papillary-renal-neoplasm-with-reverse-polarity-an-observational-study-of-histology-immunophenotypes-and-molecular-variation
#1
JOURNAL ARTICLE
Huan Han, Shu-Yi Yin, Rui-Xiang Song, Jing Zhao, Yong-Wei Yu, Miao-Xia He, Han Wang
BACKGROUND: Papillary renal neoplasm with reverse polarity (PRNRP) is a novel entity with unique clinicopathological characteristics, and only a small number of patients with PRNRP have been described. METHODS: We retrospectively analyzed the data for nine patients with PRNRP and evaluated differences in the clinical, histomorphological, immunohistochemical, and molecular features; prognosis; and differential diagnosis of PRNRP from other renal tumors with papillary structure...
March 31, 2024: Translational Andrology and Urology
https://read.qxmd.com/read/38590968/prognostic-properties-of-the-baseline-prostate-specific-antigen-value-insights-from-the-european-randomized-study-of-screening-for-prostate-cancer
#2
EDITORIAL
Thomas Paul Scherer, C├ędric Poyet
No abstract text is available yet for this article.
March 31, 2024: Translational Andrology and Urology
https://read.qxmd.com/read/38590967/real-world-retrospective-study-of-prostate-specific-antigen-and-safety-assessment-with-darolutamide-plus-androgen-deprivation-therapy-for-metastasis-hormone-sensitive-prostate-cancer
#3
JOURNAL ARTICLE
Jia Liu, Shenghan Wang, Yong Yang, Shuo Wang, Davide Campobasso, Yu Guang Tan, Qiang Gao, Lin Yang, Yudong Cao, Yongpeng Ji, Peng Du, Bao Zhang
BACKGROUND: ARASENS has demonstrated the efficacy and safety for darolutamide (DARO) with androgen deprivation therapy (ADT) plus docetaxel in metastasis hormone-sensitive prostate cancer (mHSPC). There is a lack of reports for DARO with ADT in mHSPC though the regimen is used in clinical from time to time. Moreover, recent studies have supported the importance of early and rapid prostate-specific antigen (PSA) reduction, which correlates with reduced disease progression and improved survival in patients with mHSPC...
March 31, 2024: Translational Andrology and Urology
https://read.qxmd.com/read/38590966/is-dismissing-preoperative-pregabalin-premature-the-role-of-gabapentinoids-in-multimodal-pain-management-following-ureteroscopic-stone-surgery
#4
EDITORIAL
Robert Qi, Kevin Koo
No abstract text is available yet for this article.
March 31, 2024: Translational Andrology and Urology
https://read.qxmd.com/read/38590965/urethronav-the-aetiology-and-extent-of-idiopathic-urethral-stricture-in-an-australian-population
#5
JOURNAL ARTICLE
Devang Desai, William Harrison, Sheliyan Raveenthiran, Hemamali Samaratunga, Gunter De Win
BACKGROUND: Lichen sclerosus (LS) is considered a causative factor in 10% of cases of idiopathic urethral stricture disease (IUSD), which is important for determining management strategies due to the underlying pathophysiology. Traditional excision urethroplasty may not be effective as inflammation often extends beyond the macroscopic stricture. This pilot study aims to answer two research questions: is LS an underlying cause of some idiopathic cause of strictures, and, if there is histological evidence suggesting predisposition of the surrounding tissue to strictures...
March 31, 2024: Translational Andrology and Urology
https://read.qxmd.com/read/38590964/extracellular-vesicles-and-prostate-cancer-management-a-narrative-review
#6
REVIEW
Fumihiko Urabe, Yuta Yamada, Shutaro Yamamoto, Shunsuke Tsuzuki, Shoji Kimura, Takahiro Ochiya, Takahiro Kimura
BACKGROUND AND OBJECTIVE: Prostate cancer (PCa) is the second most common male cancer in the United States. Although new drugs have recently been approved, clinical challenges remain, notably the precise detection and prognostic implications of drug-resistant PCa. Extracellular vesicles (EVs), nanoscale lipid membrane vesicles, are actively secreted into the extracellular milieu by a variety of cell types. Over the past decade, interest in EVs has grown, and emerging evidence suggests that EVs play pivotal roles in cancer biology...
March 31, 2024: Translational Andrology and Urology
https://read.qxmd.com/read/38590963/gunshot-wound-injury-to-the-genitourinary-tract-a-4-year-retrospective-review-at-an-academic-level-1-trauma-center
#7
JOURNAL ARTICLE
Ademilola Tejuoso, Abigail George, Sarah Johnson, Anne E Geller, Parris Kapple, Craig Ziegler, Keith Miller, Kellen Choi
BACKGROUND: Firearm injuries increased significantly during the coronavirus disease 2019 (COVID-19) pandemic. We aimed to describe our experience with patients admitted to a level 1 trauma center with gunshot-related trauma to the genitourinary (GU) tract before and during COVID-19 pandemic. METHODS: Patients sustaining gunshot-related trauma to the adrenals, kidneys, ureters, bladder, scrotum, testicles, penis, and urethra between January 1, 2018 and December 31, 2021 were identified from our institutional trauma database...
March 31, 2024: Translational Andrology and Urology
https://read.qxmd.com/read/38590962/effects-of-electroacupuncture-on-chronic-urinary-retention-after-pelvic-or-lumbosacral-tumor-resection-surgeries-a-retrospective-cohort-study
#8
JOURNAL ARTICLE
Min Yang, Lili Zhu, Hao Yao, Yu Chen, Zhishun Liu
BACKGROUND: Chronic urinary retention (CUR) resulting from lower motor neuron lesions (LMNL) is a medical condition secondary to pelvic or lumbosacral tumor resection surgeries. Electroacupuncture (EA) is proved to be effective and safe in treating certain lower urinary tract disorders. However, the clinical benefit and optimal duration of EA treatment for CUR following LMNL remain unknown. METHODS: Using a retrospective cohort design, 20 eligible patients diagnosed with CUR resulting from LMNL secondary to pelvic or lumbosacral tumor resection surgeries were included from March 1, 2017, to June 30, 2020...
March 31, 2024: Translational Andrology and Urology
https://read.qxmd.com/read/38590961/disease-progression-in-bacillus-calm%C3%A3-tte-guerin-unresponsive-non-muscle-invasive-bladder-cancer-patients-with-carcinoma-in-situ-participating-in-clinical-trials-on-bladder-sparing-treatment
#9
JOURNAL ARTICLE
Olga M Pijpers, Joost L Boormans
No abstract text is available yet for this article.
March 31, 2024: Translational Andrology and Urology
https://read.qxmd.com/read/38590960/prenatal-dehp-exposure-induces-lifelong-testicular-toxicity-by-continuously-interfering-with-steroidogenic-gene-expression
#10
JOURNAL ARTICLE
Qigen Xie, Haiming Cao, Hanchao Liu, Kai Xia, Yong Gao, Chunhua Deng
BACKGROUND: Epidemiologic studies suggested the association between prenatal di-(2-ethylhexyl) phthalate (DEHP) exposure and disorders of sex development (DSD), adult male disorders, and reproductive aging. Inhibiting testosterone synthesis by interfering with steroidogenic gene expression induces testicular toxicity, however, whether prenatal DEHP exposure induces testicular toxicity through this mechanism remains uncertain. METHODS: C57BL/6JGpt male mice underwent different doses (0, 100, 500, 1,000 mg/kg) of prenatal DEHP exposure during gestational day 10 to delivery day, the testicular toxicity (genital development, testosterone, semen quality, and morphology of testis tissue) in the neonatal, post-puberal and middle-aged stages was observed, and the steroidogenic gene ( Lhcgr , Star , Cyp11a1 , Cyp17a1 , Hsd17b3 , and Hsd3b2 ) expression was analyzed by quantitative polymerase chain reaction (qPCR) and Western blot (WB)...
March 31, 2024: Translational Andrology and Urology
https://read.qxmd.com/read/38590959/an-update-on-the-genetic-predisposition-of-testicular-germ-cell-tumors
#11
EDITORIAL
Rashidul Islam, Aylin Hansen, Annalena Liesen, Hubert Schorle
No abstract text is available yet for this article.
March 31, 2024: Translational Andrology and Urology
https://read.qxmd.com/read/38590958/contemporary-role-of-avelumab-first-line-maintenance-in-advanced-urothelial-carcinoma-with-consideration-of-the-javelin-bladder-100-comprehensive-clinical-subgroup-analyses
#12
EDITORIAL
Kevin K Zarrabi, Benjamin Miron, Daniel M Geynisman
No abstract text is available yet for this article.
March 31, 2024: Translational Andrology and Urology
https://read.qxmd.com/read/38590957/biomarker-challenges-in-the-pursuit-of-personalized-neoadjuvant-chemotherapy-for-muscle-invasive-bladder-cancer-conclusions-from-swog-s1314
#13
EDITORIAL
Sandra Kim, Marie-Pier St-Laurent, Peter Black
No abstract text is available yet for this article.
March 31, 2024: Translational Andrology and Urology
https://read.qxmd.com/read/38590956/to-see-clear-is-not-enough-it-is-the-action-that-counts
#14
EDITORIAL
Manuela Andrea Hoffmann, Finn Edler von Eyben
No abstract text is available yet for this article.
March 31, 2024: Translational Andrology and Urology
https://read.qxmd.com/read/38590955/exploring-the-capabilities-and-challenges-of-chatgpt-in-disseminating-urologic-information
#15
EDITORIAL
Amber McMahon, Cian L Jacob, Vincent G Bird, Bristol B Whiles
No abstract text is available yet for this article.
March 31, 2024: Translational Andrology and Urology
https://read.qxmd.com/read/38590954/effect-of-a-variant-histology-on-the-oncological-outcomes-of-japanese-patients-with-upper-tract-urothelial-carcinomas-after-radical-nephroureterectomy-a-multicenter-retrospective-study
#16
JOURNAL ARTICLE
Naoki Uchida, Fumihiko Urabe, Yushi Suhara, Yuma Goto, Kentaro Yoshihara, Ibuki Sadakane, Yuji Yata, Shiro Kurawaki, Keiichiro Miyajima, Mimu Ishikawa, Kazuhiro Takahashi, Kosuke Iwatani, Yu Imai, Keigo Sakanaka, Minoru Nakazono, Akira Hisakane, Takashi Kurauchi, Sotaro Kayano, Hajime Onuma, Keiichiro Mori, Koichi Aikawa, Takafumi Yanagisawa, Kojiro Tashiro, Shunsuke Tsuzuki, Jun Miki, Akira Furuta, Shun Sato, Hiroyuki Takahashi, Takahiro Kimura
BACKGROUND: An earlier systematic review and meta-analysis found that patients with a certain histological variant of upper tract urothelial carcinoma (UTUC) exhibited more advanced disease and poorer survival than those with pure UTUC. A difference in the clinicopathological UTUC characteristics of Caucasian and Japanese patients has been reported, but few studies have investigated the clinical impact of the variant histology in Japanese UTUC patients. METHODS: We retrospectively enrolled 824 Japanese patients with pTa-4N0-1M0 UTUCs who underwent radical nephroureterectomy without neoadjuvant chemotherapy...
March 31, 2024: Translational Andrology and Urology
https://read.qxmd.com/read/38481874/addressing-the-need-for-preclinical-study-of-penile-prosthesis-infection-a-new-animal-model-and-narrative-review
#17
REVIEW
Yash B Shah, Ji-Bin Liu, Priscilla Machado, Andrew Denisenko, Corinne E Wessner, Kerith R Wang, Rishabh K Simhal, Selin Isguven, Lauren J Delaney, Noreen J Hickok, Flemming Forsberg, Paul H Chung
BACKGROUND AND OBJECTIVE: Erectile dysfunction (ED) is a common condition in men, and many patients refractory to conservative treatment may undergo penile prostheses (PPs) placement. The primary concern following PP implantation is device infection. Although antibiotic and hydrophilic coatings have reduced the incidence of inflatable PP (IPP) infections, there remains room for improvement. Optimization of PP outcomes requires a practical in vivo model to better understand mechanisms of infection and to test new infection control strategies...
February 29, 2024: Translational Andrology and Urology
https://read.qxmd.com/read/38481873/combination-clomiphene-citrate-and-anastrozole-duotherapy-improves-semen-parameters-in-a-multi-institutional-retrospective-cohort-of-infertile-men
#18
JOURNAL ARTICLE
Vadim Osadchiy, Carlos Munoz-Lopez, Tommy Jiang, Bryan D Naelitz, Neel Parekh, Sarah C Vij, Jesse N Mills, Scott D Lundy, Sriram V Eleswarapu
In men with impaired semen parameters, empiric medical therapies such as clomiphene citrate, a selective estrogen receptor modulator (SERM), and anastrozole, a selective aromatase inhibitor, are often employed. The effects of jointly administering these agents on semen parameters are not well understood. Here, we describe the findings of our multi-center, retrospective cohort study of men with idiopathic primary or secondary infertility. Twenty-one men were treated with combination therapy (anastrozole and clomiphene) and 69 men were treated with monotherapy (anastrozole)...
February 29, 2024: Translational Andrology and Urology
https://read.qxmd.com/read/38481872/exploring-the-role-of-perioperative-pregabalin-in-ureteroscopy-enhanced-recovery-after-surgery-eras-protocols
#19
EDITORIAL
Runhan Ren, Connor M Forbes, Ryan F Paterson, Ben H Chew
No abstract text is available yet for this article.
February 29, 2024: Translational Andrology and Urology
https://read.qxmd.com/read/38481871/performance-analysis-of-urine-formed-element-analyzer-eh-2090-was-found-to-have-good-accuracy-in-detecting-rbcs-and-wbcs-when-compared-to-manual-microscopic
#20
JOURNAL ARTICLE
Lixia Bai, Qiaoping Xu, Zhicheng Wu
BACKGROUND: EH-2090 is Mindray's new-generation fully automatic urine formed element analyzer (hereinafter referred to as EH-2090). Currently, there are no studies on EH-2090, so we evaluated the analytical and clinical performance of this instrument to verify that it can meet daily clinical needs, and used manual microscopy as a reference method. METHODS: The analytical performance of the EH-2090 was first evaluated for repeatability, linearity, reproducibility, and carryover...
February 29, 2024: Translational Andrology and Urology
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