Simone Bianciardi, Giulia Tesi, Helena Cerutti, Alessandra Cartocci, Roberto Guerranti, Caterina Silvestrini, Sabrina Gori, Tommaso Bandini, Alessandra Brogi, Roberto Leoncini
BACKGROUND: Deficiency of Vitamin B12 and folate may determine hematological, neurological, and metabolic alterations; therefore, an accurate quantification of their serum levels is required, especially in the presence of symptoms that might suggest a deficiency. CHORUS VIT B12 and CHORUS FOLATE are two automated immunoassays, developed to quantify vitamin B12 and folate, respectively, in human serum. DESIGN AND METHODS: This single-center, non-pharmacological, diagnostic study described the validation and characterization of CHORUS VIT B12 and CHORUS FOLATE, with a specific focus on performance, precision, and reliability...
October 2023: Journal of Public Health Research