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Journals Journal of the American Heart ...

Journal of the American Heart Association

https://read.qxmd.com/read/38742541/coronary-embolism-in-st-segment-elevation-myocardial-infarction-and-atrial-fibrillation-not-one-size-fits-all
#21
EDITORIAL
Omar M Abdelfattah, Paul Kumfa, Joseph Allencherril
No abstract text is available yet for this article.
May 14, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38742535/bleeding-risk-in-patients-receiving-omega-3-polyunsaturated-fatty-acids-a-systematic-review-and-meta-analysis-of-randomized-clinical-trials
#22
JOURNAL ARTICLE
Mustafa Javaid, Kadhim Kadhim, Bilal Bawamia, Timothy Cartlidge, Mohamed Farag, Mohammad Alkhalil
BACKGROUND: There is a potential concern about increased bleeding risk in patients receiving omega-3 polyunsaturated fatty acids (PUFAs). The aims of this study-level meta-analysis were to determine the risk of bleeding and to assess whether this relationship is linked to the received dose of omega-3 PUFAs or the background use of antiplatelet treatment. METHODS AND RESULTS: Electronic databases were searched through May 2023 to identify randomized clinical trials of patients receiving omega-3 PUFAs...
May 14, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38742529/impact-of-left-ventricular-unloading-on-outcome-of-heart-transplant-bridging-with-extracorporeal-membrane-oxygenation-support-in-new-allocation-policy
#23
JOURNAL ARTICLE
Vasiliki Gregory, Kenji Okumura, Ameesh Isath, Avi Levine, Corazon De La Pena, Junichi Shimamura, David Spielvogel, Masashi Kai, Suguru Ohira
BACKGROUND: The new heart allocation policy places veno-arterial extracorporeal membrane oxygenation (VA-ECMO)-supported heart transplant (HT) candidates at the highest priority status. Despite increasing evidence supporting left ventricular (LV) unloading during VA-ECMO, the effect of LV unloading on transplant outcomes following bridging to HT with VA-ECMO remains unknown. METHODS AND RESULTS: From October 18, 2018 to March 21, 2023, 624 patients on VA-ECMO at the time of HT were identified in the United Network for Organ Sharing database and were divided into 2 groups: VA-ECMO alone (N=384) versus VA-ECMO with LV unloading (N=240)...
May 14, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38742527/to-redo-or-not-to-redo-the-role-of-mitral-transcatheter-edge-to-edge-repair-in-prior-failed-mitral-valve-repairs
#24
EDITORIAL
Tiffany Dong, Serge C Harb, Rishi Puri
No abstract text is available yet for this article.
May 14, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38742523/transcatheter-mitral-valve-repair-with-the-mitraclip-device-for-prior-mitral-valve-repair-failure-insights-from-the-giotto-fails-study
#25
JOURNAL ARTICLE
Arturo Giordano, Paolo Ferraro, Filippo Finizio, Nicola Corcione, Michele Cimmino, Giuseppe Biondi-Zoccai, Paolo Denti, Antonio Popolo Rubbio, Anna Sonia Petronio, Antonio L Bartorelli, Annalisa Mongiardo, Salvatore Giordano, Francesco De Felice, Marianna Adamo, Matteo Montorfano, Cesare Baldi, Giuseppe Tarantini, Francesco Giannini, Federico Ronco, Ida Monteforte, Emmanuel Villa, Maurizio Ferrario, Luigi Fiocca, Fausto Castriota, Angelo Squeri, Corrado Tamburino, Francesco Bedogni
BACKGROUND: Minimally invasive mitral valve repair has a favorable risk-benefit profile in patients with significant de novo mitral regurgitation. Its role in patients with prior mitral valve repair is uncertain. We aimed to appraise the outcome of patients undergoing transcatheter edge-to-edge repair (TEER) with prior transcatheter or surgical mitral valve repair (SMVR). METHODS AND RESULTS: We queried the Italian multicenter registry on TEER with MitraClip, distinguishing naïve patients from those with prior TEER or (SMVR)...
May 14, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38742522/coronary-embolism-among-patients-with-st-segment-elevation-myocardial-infarction-and-atrial-fibrillation-an-underrecognized-but-deadly-association
#26
JOURNAL ARTICLE
Batric Popovic, Jeanne Varlot, Lisa Humbertjean, Jean Marc Sellal, Nathalie Pace, Nefissa Hammache, Renaud Fay, Florian Eggenspieler, Pierre Adrien Metzdorf, Edoardo Camenzind
BACKGROUND: The prevalence and impact of coronary emboli (CE) in patients with ST-segment-elevation myocardial infarction (STEMI) and atrial fibrillation (AF) have not been specifically studied. The objective was to describe the clinical characteristics and outcomes of patients with AF and CE in a large series of patients with STEMI. METHODS AND RESULTS: We investigated 2292 consecutive patients with STEMI and among them 225 patients with AF: 46 patients with a STEMI related to CE (group A) and 179 patients with a STEMI related to an atherosclerotic cause (group B)...
May 14, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38742509/computed-tomography-angiography-characteristics-of-thin-cap-fibroatheroma-in-patients-with-diabetes
#27
JOURNAL ARTICLE
Keishi Suzuki, Daisuke Kinoshita, Takayuki Niida, Haruhito Yuki, Daichi Fujimoto, Damini Dey, Hang Lee, Iris McNulty, Masamichi Takano, Kyoichi Mizuno, Maros Ferencik, Tsunekazu Kakuta, Ik-Kyung Jang
BACKGROUND: It was recently reported that thin-cap fibroatheroma (TCFA) detected by optical coherence tomography was an independent predictor of future cardiac events in patients with diabetes. However, the clinical usefulness of this finding is limited by the invasive nature of optical coherence tomography. Computed tomography angiography (CTA) characteristics of TCFA have not been systematically studied. The aim of this study was to investigate CTA characteristics of TCFA in patients with diabetes...
May 14, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38726925/angiotensin-ii-directly-increases-endothelial-calcium-and-nitric-oxide-in-kidney-and-brain-microvessels-in%C3%A2-vivo-with-reduced-efficacy-in-hypertension
#28
JOURNAL ARTICLE
Alejandra Becerra Calderon, Urvi Nikhil Shroff, Sachin Deepak, Audrey Izuhara, Greta Trogen, Alicia A McDonough, Susan B Gurley, Jonathan W Nelson, János Peti-Peterdi, Georgina Gyarmati
BACKGROUND: The vasoconstrictor effects of angiotensin II via type 1 angiotensin II receptors in vascular smooth muscle cells are well established, but the direct effects of angiotensin II on vascular endothelial cells (VECs) in vivo and the mechanisms how VECs may mitigate angiotensin II-mediated vasoconstriction are not fully understood. The present study aimed to explore the molecular mechanisms and pathophysiological relevance of the direct actions of angiotensin II on VECs in kidney and brain microvessels in vivo...
May 10, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38726923/prognostic-value-of-objective-social-isolation-and-loneliness-in-older-patients-with-heart-failure-subanalysis-of-fragile-hf-and-kitasato-cohort
#29
JOURNAL ARTICLE
Hiroshi Saito, Daichi Maeda, Nobuyuki Kagiyama, Tsutomu Sunayama, Taishi Dotare, Yudai Fujimoto, Kentaro Jujo, Kazuya Saito, Shota Uchida, Nobuaki Hamazaki, Kentaro Kamiya, Yuki Ogasahara, Emi Maekawa, Masaaki Konishi, Takeshi Kitai, Kentaro Iwata, Hiroshi Wada, Takatoshi Kasai, Hirofumi Nagamatsu, Junya Ako, Shin-Ichi Momomura, Yuya Matsue
BACKGROUND: Social factors encompass a broad spectrum of nonmedical factors, including objective (social isolation [SI]) and perceived (loneliness) conditions. Although social factors have attracted considerable research attention, information regarding their impact on patients with heart failure is scarce. We aimed to investigate the prognostic impact of objective SI and loneliness in older patients with heart failure. METHODS AND RESULTS: This study was conducted using the FRAGILE-HF (Prevalence and Prognostic Value of Physical and Social Frailty in Geriatric Patients Hospitalized for Heart Failure; derivation cohort) and Kitasato cohorts (validation cohort), which included hospitalized patients with heart failure aged ≥65 years...
May 10, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38726922/antithrombotic-treatment-and-clinical-outcomes-after-intracerebral-hemorrhage-a-retrospective-cohort-study-from-the-swedish-stroke-register
#30
JOURNAL ARTICLE
Mattias Tallroth, Ruzan Udumyan, András Büki, Mia von Euler
BACKGROUND: A rapid shift has occurred from vitamin K antagonists toward direct oral anticoagulants, which have a lower risk of intracerebral hemorrhage (ICH). However, effects on clinical outcomes after ICH are understudied. We aimed to describe the prevalence of antithrombotic drugs and to study the prognosis among prestroke functionally independent Swedish patients with ICH. METHODS AND RESULTS: We identified all patients diagnosed with nontraumatic ICH in 2017 to 2021 from the Swedish Stroke Register (n=13 155) and assessed death and functional outcome at 3 months after ICH in prestroke functionally independent patients (n=10 014)...
May 10, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38726920/prognostic-value-and-determinants-of-high-sensitivity-cardiac-troponin-t-in-patients-with-a-systemic-right-ventricle-insights-from-the-serve-trial
#31
JOURNAL ARTICLE
Francisco Javier Ruperti-Repilado, Fabian Tran, Philip Haaf, Pedro Lopez-Ayala, Matthias Greutmann, Markus Schwerzmann, Judith Bouchardy, Harald Gabriel, Dominik Stambach, Tobias Rutz, Juerg Schwitter, Kerstin Wustmann, Michael Freese, Christian Mueller, Daniel Tobler
BACKGROUND: The determinants and prognostic value of high-sensitivity cardiac troponin T (hs-cTnT) among patients with a systemic right ventricle are largely unknown. METHODS AND RESULTS: Ninety-eight patients from the randomized controlled SERVE (Effect of Phosphodiesterase-5 Inhibition With Tadalafil on Systemic Right Ventricular Size and Function) trial were included. The correlation between baseline hs-cTnT concentrations and biventricular volumes and function quantified by cardiac magnetic resonance or cardiac multirow detector computed tomography was assessed by adjusted linear regression models...
May 10, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38726919/blood-lipids-lipoproteins-and-apolipoproteins-with-risk-of-coronary-heart-disease-a-prospective-study-among-racially-diverse-populations
#32
JOURNAL ARTICLE
Kui Deng, Xiong-Fei Pan, Markus W Voehler, Qiuyin Cai, Hui Cai, Xiao-Ou Shu, Deepak K Gupta, Loren Lipworth, Wei Zheng, Danxia Yu
BACKGROUND: Comprehensive blood lipoprotein profiles and their association with incident coronary heart disease (CHD) among racially and geographically diverse populations remain understudied. METHODS AND RESULTS: We conducted nested case-control studies of CHD among 3438 individuals (1719 pairs), including 1084 White Americans (542 pairs), 1244 Black Americans (622 pairs), and 1110 Chinese adults (555 pairs). We examined 36 plasma lipids, lipoproteins, and apolipoproteins, measured by nuclear magnetic resonance spectroscopy, with incident CHD among all participants and subgroups by demographics, lifestyle, and metabolic health status using conditional or unconditional logistic regression adjusted for potential confounders...
May 10, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38726918/ten-year-outcome-of-recanalization-or-medical-therapy-for-concomitant-chronic-total-occlusion-after-myocardial-infarction
#33
JOURNAL ARTICLE
Anna van Veelen, Casper F Coerkamp, Yvemarie B O Somsen, Truls Råmunddal, Dan Ioanes, Peep Laanmets, René J van der Schaaf, Erlend Eriksen, Matthijs Bax, Maarten Jan Suttorp, Bradley H Strauss, Emanuele Barbato, Koen M Marques, Martijn Meuwissen, Olivier Bertrand, Martin van der Ent, Paul Knaapen, Jan G P Tijssen, Bimmer E P M Claessen, Loes P C Hoebers, Joëlle Elias, José P S Henriques
BACKGROUND: The EXPLORE (Evaluating Xience and Left Ventricular Function in PCI on Occlusions After STEMI) trial was the first and only randomized trial investigating chronic total occlusion (CTO) percutaneous coronary intervention (PCI) early after primary PCI for ST-segment-elevation myocardial infarction, compared with medical therapy for the CTO. We performed a 10-year follow-up of EXPLORE to investigate long-term safety and clinical impact of CTO PCI after ST-segment-elevation myocardial infarction, compared with no-CTO PCI...
May 10, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38726915/five-year-cumulative-cardiovascular-health-and-clinical-events-in-patients-with-chronic-kidney-disease-the-cric-study
#34
JOURNAL ARTICLE
Qiuyu Cao, Yufang Bi, Flor Alvarado, Amanda H Anderson, Katherine T Mills, Byron C Jaeger, Jing Chen, Jiang He, Joshua D Bundy
BACKGROUND: Higher cardiovascular health (CVH) score is associated with lower risks of cardiovascular disease (CVD) and mortality in the general population. However, it is unclear whether cumulative CVH is associated with CVD, end-stage kidney disease (ESKD), and death in patients with chronic kidney disease. METHODS AND RESULTS: Among individuals from the prospective CRIC (Chronic Renal Insufficiency Cohort) Study, we used the percentage of the maximum possible CVH score attained from baseline to the year 5 visit to calculate cumulative CVH score...
May 10, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38726914/risk-of-heart-disease-in-patients-with-amputation-a-nationwide-cohort-study-in-south-korea
#35
JOURNAL ARTICLE
Hea Lim Choi, Jung Eun Yoo, Miso Kim, Bongsung Kim, Junhee Park, Won Hyuk Chang, Heesun Lee, Kyungdo Han, Dong Wook Shin
BACKGROUND: Amputation confers disabilities upon patients and is linked to substantial morbidity and death attributed to heart disease. While some studies have focused on traumatic amputees in veterans, few studies have focused on traumatic amputees within the general population. Therefore, the present study aimed to assess the risk of heart disease in patients with traumatic amputation with disability within the general population using a large-scale nationwide population-based cohort...
May 10, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38726910/prediction-of-24-hour-urinary-sodium-excretion-using-machine-learning-algorithms
#36
JOURNAL ARTICLE
Rikuta Hamaya, Molin Wang, Stephen P Juraschek, Kenneth J Mukamal, JoAnn E Manson, Deirdre K Tobias, Qi Sun, Gary C Curhan, Walter C Willett, Eric B Rimm, Nancy R Cook
BACKGROUND: Accurate quantification of sodium intake based on self-reported dietary assessments has been a persistent challenge. We aimed to apply machine-learning (ML) algorithms to predict 24-hour urinary sodium excretion from self-reported questionnaire information. METHODS AND RESULTS: We analyzed 3454 participants from the NHS (Nurses' Health Study), NHS-II (Nurses' Health Study II), and HPFS (Health Professionals Follow-Up Study), with repeated measures of 24-hour urinary sodium excretion over 1 year...
May 10, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38726905/reduced-sclerostin-expression-in-human-atherosclerotic-plaques-links-to-ischemic-stroke
#37
JOURNAL ARTICLE
Fabienne Burger, Aline Roth, François Mach, Cyril Thouverey, Serge L Ferrari, Kapka Miteva
No abstract text is available yet for this article.
May 10, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38726904/prevalence-predictors-and-outcomes-of-type-2-nstemi-in-hospitalized-patients-with-covid-19
#38
JOURNAL ARTICLE
Sahishnu Patel, Alexis Visotcky, Adam Devine, Vishwajit Kode, Srisha Kotlo, Michael Aljadah, Rodney Sparapani, Jacquelyn Kulinski
BACKGROUND: Data on the incidence of type 2 non-ST-segment-elevation myocardial infarction (T2MI) in hospitalized patients with COVID-19 has been limited to single-center studies. Given that certain characteristics, such as obesity and type 2 diabetes, have been associated with higher mortality in COVID-19 infections, we aimed to define the incidence of T2MI in a national cohort and identify pre-hospital patient characteristics associated with T2MI in hospitalized patients with COVID-19...
May 10, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38726902/association-between-family-history-and-early-onset-atrial-flutter-across-racial-and-ethnic-groups
#39
JOURNAL ARTICLE
Anish S Shah, Ana Ongtengco, Victor Qiao, Yining Chen, Annette Diaz, Michael Hill, Adarsh Bhan, David S Tofovic, Dawood Darbar
BACKGROUND: Genetic and familial contributions to early-onset atrial fibrillation are described primarily in individuals of European ancestry. However, the role of racial and familial contributions in the pathogenesis of early-onset atrial flutter (EOAFL) is unclear. METHODS AND RESULTS: In this cross-sectional study, participants were enrolled prospectively from 2015 to 2021 in multiple academic centers with a diagnosis of atrial flutter (AFL) confirmed by ECG...
May 10, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38726901/agreement-of-fractional-flow-reserve-estimated-by-computed-tomography-with-invasively-measured-fractional-flow-reserve-a-systematic-review-and-meta-analysis
#40
JOURNAL ARTICLE
Thomas I Faulder, Kurundeniya Prematunga, Soniah B Moloi, Lauren E Faulder, Rhondda Jones, Joseph V Moxon
BACKGROUND: Fractional flow reserve (FFR) is the ratio of blood pressure measured distal to a stenosis and pressure proximal to a stenosis. FFR can be estimated noninvasively using computed tomography (CT) although the usefulness of this technique remains controversial. This meta-analysis evaluated the agreement of FFR estimated by CT (FFR-CT) with invasively measured FFR. The study also evaluated the diagnostic accuracy of FFR-CT, defined as the ability of FFR-CT to classify lesions as hemodynamically significant (invasive FFR ≤0...
May 10, 2024: Journal of the American Heart Association
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