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Journals Journal of the American Heart ...

Journal of the American Heart Association

https://read.qxmd.com/read/38533990/primary-and-secondary-intracerebral-hemorrhage-in-pregnant-and-nonpregnant-young-adults-by-smash-up-criteria
#1
JOURNAL ARTICLE
Mehriban Sariyeva, Noora Haghighi, Amanda Mitchell, Whitney A Booker, Nils H Petersen, Andrea D Shields, Shivani Ghoshal, Sachin Agarwal, Soojin Park, Jan Claassen, E Sander Connolly, David J Roh, Eliza C Miller
BACKGROUND: Intracerebral hemorrhage (ICH) is a major cause of maternal morbidity, but its pathophysiology is poorly characterized. We investigated characteristics of pregnancy-associated ICH (P-ICH), compared with ICH in similar aged nonpregnant adults of both sexes. METHODS AND RESULTS: We performed a retrospective analysis of 134 adults aged 18 to 44 years admitted to our center with nontraumatic ICH from January 1, 2012, to December 31, 2021. We compared ICH characteristics among 3 groups: those with P-ICH (pregnant or within 12 months of end of pregnancy); nonpregnant women; and men...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533986/baseline-uric-acid-levels-and-intravenous-thrombolysis-outcomes-in-patients-with-acute-ischemic-stroke-a-prospective-cohort-study
#2
JOURNAL ARTICLE
Peng Zhang, Rui Wang, Zhen-Ni Guo, Hang Jin, Yang Qu, Qing Zhen, Yi Yang
BACKGROUND: The study aimed to investigate the relationship between uric acid (UA) levels and functional outcomes at 3 months in patients with acute ischemic stroke (AIS) who underwent intravenous thrombolysis (IVT). METHODS AND RESULTS: This prospective cohort study included 1001 consecutive patients with AIS who underwent IVT. The correlation between UA levels and post-IVT AIS outcomes was examined. Any nonlinear relationship was assessed using a restricted cubic spline function...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533985/tumor-necrosis-factor-inhibitor-use-increases-birthweight-in-pregnant-women-with-rheumatoid-arthritis-independently-of-the-soluble-fms-like-tyrosine-kinase-1-placental-growth-factor-ratio
#3
JOURNAL ARTICLE
Cornelia H Quaak, Anna C M Kluivers, Sara J Baart, Hieronymus T W Smeele, Rugina I Neuman, Langeza Saleh, Willy Visser, A H Jan Danser, Radboud J E M Dolhain
BACKGROUND: To study whether the use of TNF (tumor necrosis factor) inhibitors (TNFi) by pregnant women with rheumatoid arthritis affects sFlt-1 (soluble Fms-like tyrosine kinase-1), PlGF (placental growth factor), or their impact on birthweight. METHODS AND RESULTS: sFlt-1 and PlGF were measured in all trimesters of pregnancy in the Preconception Counseling in Active Rheumatoid Arthritis study and were compared according to the use of TNFi. The association of sFlt-1 and PlGF with birthweight in relation to TNFi was determined...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533983/risk-of-death-and-cardiovascular-events-in-asian-patients-with-atrial-fibrillation-and-chronic-obstructive-pulmonary-disease-a-report-from-the-prospective-aphrs-registry
#4
JOURNAL ARTICLE
Tommaso Bucci, Giulio Francesco Romiti, Alena Shantsila, Wee-Siong Teo, Hyung-Wook Park, Wataru Shimizu, Bernadette Corica, Marco Proietti, Hung-Fat Tse, Tze-Fan Chao, Frederick Frost, Gregory Y H Lip
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is associated with an increased risk of adverse events in patients with atrial fibrillation (AF); however, few data are available on this topic in Asian populations. METHODS AND RESULTS: Prospective observational study conducted on patients with AF enrolled in the Asia-Pacific Heart Rhythm Society (APHRS) AF Registry. The diagnosis of COPD was based on data reported in the case report form by the investigators...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533982/social-media-posts-on-statins-what-can-we-learn-about-patient-experiences-and-perspectives
#5
EDITORIAL
Su Golder, Ari Klein, Karen O'Connor, Yunwen Wang, Graciela Gonzalez-Hernandez
No abstract text is available yet for this article.
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533981/highlights-from-the-society-for-cardiovascular-angiography-interventions-scai-scientific-sessions-2023
#6
JOURNAL ARTICLE
Fathima Aaysha Cader, Nouman Arshad, Jennifer A Tremmel
No abstract text is available yet for this article.
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533977/magnetic-resonance-imaging-assists-with-determining-etiology-after-transient-ischemic-attack-or-minor-stroke
#7
JOURNAL ARTICLE
Margaret Moores, Raed A Joundi, Nishita Singh, Andrew M Penn, Kristine Votova, Eric E Smith, Shelagh B Coutts
BACKGROUND: Magnetic resonance imaging infarct topography may assist with determining stroke etiology. The influence of diffusion-weighted imaging (DWI)-positive lesions on etiology determination in patients with transient ischemic attack or minor stroke is not well studied. METHODS AND RESULTS: We prospectively enrolled patients between 2010 and 2017 in 2 studies; participants with a final diagnosis of probable or definite transient ischemic attack or stroke were pooled for analysis...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533976/shared-genetic-features-of-psoriasis-and-myocardial-infarction-insights-from-a-weighted-gene-coexpression-network-analysis
#8
JOURNAL ARTICLE
Qiaoyu Zhou, Ruizheng Shi
BACKGROUND: Increasing evidence suggests a higher propensity for acute myocardial infarction (MI) in patients with psoriasis. However, the shared mechanisms underlying this comorbidity in these patients remain unclear. This study aimed to explore the shared genetic features of psoriasis and MI and to identify potential biomarkers indicating their coexistence. METHODS AND RESULTS: Data sets obtained from the gene expression omnibus were examined using a weighted gene coexpression network analysis approach...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533974/return-to-work-after-refractory-out-of-hospital-cardiac-arrest-in-patients-managed-with-or-without-extracorporeal-cardiopulmonary-resuscitation-a-nationwide-register-based-study
#9
JOURNAL ARTICLE
Emilie Gregers, Kristian Kragholm, Louise Linde, Sivagowry Rasalingam Mørk, Jo Bønding Andreasen, Christian Juhl Terkelsen, Jens Flensted Lassen, Jacob Eifer Møller, Helle Laugesen, Morten Smerup, Jesper Kjærgaard, Peter Hasse Møller-Sørensen, Lene Holmvang, Christian Torp-Pedersen, Christian Hassager, Helle Søholm
BACKGROUND: Extracorporeal cardiopulmonary resuscitation (ECPR) is increasingly used for refractory out-of-hospital cardiac arrest (OHCA). However, survivors managed with ECPR are at risk of poor functional status. The purpose of this study was to investigate return to work (RTW) after refractory OHCA. METHODS AND RESULTS: Of 44 360 patients with OHCA in the period of 2011 to 2020, this nationwide registry-based study included 805 patients with refractory OHCA in the working age (18-65 years) who were employed before OHCA (2% of the total OHCA cohort)...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533972/heart-rate-variability-deceleration-capacity-of-heart-rate-and-death-a-veteran-twins-study
#10
JOURNAL ARTICLE
Minxuan Huang, Amit J Shah, Rachel Lampert, Donald L Bliwise, Dayna A Johnson, Gari D Clifford, Richard Sloan, Jack Goldberg, Yi-An Ko, Giulia Da Poian, Erick A Perez-Alday, Zakaria Almuwaqqat, Anish Shah, Mariana Garcia, An Young, Kasra Moazzami, J Douglas Bremner, Viola Vaccarino
BACKGROUND: Autonomic function can be measured noninvasively using heart rate variability (HRV), which indexes overall sympathovagal balance. Deceleration capacity (DC) of heart rate is a more specific metric of vagal modulation. Higher values of these measures have been associated with reduced mortality risk primarily in patients with cardiovascular disease, but their significance in community samples is less clear. METHODS AND RESULTS: This prospective twin study followed 501 members from the VET (Vietnam Era Twin) registry...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533970/cardiomyopathy-in-patients-with-acute-ischemic-stroke-and-methamphetamine-use-relevance-for-cardioembolic-stroke-and-outcome
#11
JOURNAL ARTICLE
Sook Joung Lee, Shimeng Liu, Haley Blackwill, Dana Stradling, Mohammad Shafie, Wengui Yu
BACKGROUND: Methamphetamine use has emerged as a major risk factor for cardiovascular and cerebrovascular disease in young adults. The aim of this study was to investigate a possible association of methamphetamine use with cardioembolic stroke. METHODS AND RESULTS: We performed a retrospective study of patients with acute ischemic stroke admitted at our medical center between 2019 and 2022. All patients were screened for methamphetamine use and cardiomyopathy, defined as left ventricular ejection fraction ≤45%...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533967/impact-of-a-medical-fitness-model-on-incident-major-adverse-cardiovascular-events-a-prospective-cohort-study-of-11%C3%A2-000-members
#12
JOURNAL ARTICLE
Ranveer Brar, Reid H Whitlock, Alan Katz, Michelle Di Nella, Paul Komenda, Clara Bohm, Claudio Rigatto, Navdeep Tangri, Carrie Solmundson, David Collister
BACKGROUND: Cardiovascular disease remains the leading cause of disease burden and death in the world. The medical fitness model may be an alternative public health strategy to address cardiovascular risk factors with medical integrated programming. METHODS AND RESULTS: We performed a retrospective cohort study between January 1, 2005, and December 31, 2015. Adults (aged ≥18 years) who did not have a prior major adverse cardiovascular event were included...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533965/correction-to-intravascular-imaging-findings-after-pci-in-patients-with-focal-and-diffuse-coronary-artery-disease
#13
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533964/rv1-rv3-index-to-differentiate-idiopathic-ventricular-arrhythmias-arising-from-right-ventricular-outflow-tract-and-aortic-sinus-of-valsalva-a-multicenter-study
#14
JOURNAL ARTICLE
Ning Chen, Lei Wang, Jincheng Jiao, Weizhu Ju, Zhe Wang, Cao Zou, Fu Yi, Fangyi Xiao, Wenzhi Shen, Chengzong Li, Linsheng Shi, Long Chen, Yuan Ji, Youquan Wei, Kai Gu, Gang Yang, Hongwu Chen, Mingfang Li, Hailei Liu, Minglong Chen
BACKGROUND: This study aimed to investigate the predictive value of parameters of every precordial lead and their combinations in differentiating between idiopathic ventricular arrhythmias (IVAs) from the right ventricular outflow tract and aortic sinus of Valsalva (ASV). METHODS AND RESULTS: Between March 1, 2018, and December 1, 2021, consecutive patients receiving successful ablation of right ventricular outflow tract or ASV IVAs were enrolled. The amplitude and duration of the R wave and S wave were measured in every precordial lead during IVAs...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533963/left-atrial-cardiomyopathy-a-puzzling-disease-process-short-of-an-easy-answer
#15
EDITORIAL
Adrian M Petzl, Rajat Deo
No abstract text is available yet for this article.
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533962/lower-recurrence-rates-of-atrial-fibrillation-and-mace-events-after-early-compared-to-late-ablation-a-danish-nationwide-register-study
#16
JOURNAL ARTICLE
Jacob Tønnesen, Martin H Ruwald, Jannik Pallisgaard, Peter Vibe Rasmussen, Arne Johannessen, Jim Hansen, Rene H Worck, Christopher R Zörner, Lise Riis-Vestergaard, Charlotte Middelfart, Samuel K Sørensen, Stefan Sattler, Gunnar Gislason, Morten Lock Hansen
BACKGROUND: Guidelines recommend prioritizing treatment with antiarrhythmic drugs before referral of patients with atrial fibrillation to ablation, delaying a potential subsequent ablation. However, delaying ablation may affect ablation outcomes. We sought to investigate the impact of duration from diagnosis to ablation on the risk of atrial fibrillation recurrence and adverse events. METHODS AND RESULTS: Using Danish nationwide registries, all patients with first-time ablation for atrial fibrillation were identified and included from 2010 to 2018...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533961/correlates-of-plasma-nt-probnp-cyclic-gmp-ratio-in-heart-failure-with-preserved-ejection-fraction-an-analysis-of-the-relax-trial
#17
JOURNAL ARTICLE
Leonard Chiu, Vineet Agrawal, David Armstrong, Evan Brittain, Sheila Collins, Anna R Hemnes, Joseph A Hill, JoAnn Lindenfeld, Sanjiv J Shah, Lynne W Stevenson, Thomas J Wang, Deepak K Gupta
BACKGROUND: Phosphodiesterases degrade cyclic GMP (cGMP), the second messenger that mediates the cardioprotective effects of natriuretic peptides. High natriuretic peptide/cGMP ratio may reflect, in part, phosphodiesterase activity. Correlates of natriuretic peptide/cGMP in patients with heart failure with preserved ejection fraction are not well understood. Among patients with heart failure with preserved ejection fraction in the RELAX (Phosphodiesterase-5 Inhibition to Improve Clinical Status and Exercise Capacity in Heart Failure With Preserved Ejection Fraction) trial, we examined (1) cross-sectional correlates of circulating NT-proBNP (N-terminal pro-B-type natriuretic peptide)/cGMP ratio, (2) whether selective phosphodiesterase-5 inhibition by sildenafil changed the ratio, and (3) whether the effect of sildenafil on 24-week outcomes varied by baseline ratio...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533960/frailty-and-metabolic-vulnerability-in-heart-failure-a-community-cohort-study
#18
JOURNAL ARTICLE
Sant Kumar, Katherine M Conners, Joseph J Shearer, Jungnam Joo, Sarah Turecamo, Maureen Sampson, Anna Wolska, Alan T Remaley, Margery A Connelly, James D Otvos, Nicholas B Larson, Suzette J Bielinski, Véronique L Roger
BACKGROUND: Frailty is common in heart failure (HF) and is associated with death but not routinely captured clinically. Frailty is linked with inflammation and malnutrition, which can be assessed by a novel plasma multimarker score: the metabolic vulnerability index (MVX). We sought to evaluate the associations between frailty and MVX and their prognostic impact. METHODS AND RESULTS: In an HF community cohort (2003-2012), we measured frailty as a proportion of deficits present out of 32 physical limitations and comorbidities, MVX by nuclear magnetic resonance spectroscopy, and collected extensive longitudinal clinical data...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533959/health-factors-associated-with-development-and-severity-of-poststroke-dysphagia-an-epidemiological-investigation
#19
JOURNAL ARTICLE
Brittany N Krekeler, Heidi J P Schieve, Jane Khoury, Lili Ding, Mary Haverbusch, Kathleen Alwell, Opeolu Adeoye, Simona Ferioloi, Jason Mackey, Daniel Woo, Matthew Flaherty, Felipe De Los Rios La Rosa, Stacie Demel, Michael Star, Elisheva Coleman, Kyle Walsh, Sabreena Slavin, Adam Jasne, Eva Mistry, Dawn Kleindorfer, Brett Kissela
BACKGROUND: Dysphagia after stroke is common and can impact morbidity and death. The purpose of this population-based study was to determine specific epidemiological and health risk factors that impact development of dysphagia after acute stroke. METHODS AND RESULTS: Ischemic and hemorrhagic stroke cases from 2010 and 2015 were identified via chart review from the GCNKSS (Greater Cincinnati Northern Kentucky Stroke Study), a representative sample of ≈1.3 million adults from southwestern Ohio and northern Kentucky...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533958/associations-of-alcohol-consumption-with-left-atrial-morphology-and-function-in-a-population-at-high-cardiovascular-risk
#20
JOURNAL ARTICLE
Aniqa B Alam, Estefania Toledo-Atucha, Dora Romaguera, Angel M Alonso-Gómez, Miguel A Martínez-Gonzalez, Lucas Tojal-Sierra, Marta Noris Mora, Caterina Mas-Llado, Linzi Li, Ines Gonzalez-Casanova, Jordi Salas-Salvadó, Montserrat Fitó, Alvaro Alonso
BACKGROUND: Excessive alcohol consumption has been associated with increased risk of atrial fibrillation, although the underlying mechanisms remain unclear. An enlarged left atrium and impaired left atrial function may lead to atrial fibrillation. The association of alcohol consumption with structural and functional left atrial measures, however, has received limited attention. METHODS AND RESULTS: We studied 503 participants from the PREDIMED-Plus (Prevención con Dieta Mediterránea) trial, a randomized trial testing intensive weight loss intervention with an energy-reduced Mediterranean diet and physical activity promotion in preventing cardiovascular disease in adults with metabolic syndrome...
March 27, 2024: Journal of the American Heart Association
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