Benjamin Batteux, Alban Nowak, Alice Séjourné, Clémence Penet, Kamel Masmoudi, François Brazier, Solène M Laville, Youssef Bennis, Valérie Gras-Champel, Gabriel Choukroun, Sophie Liabeuf
BACKGROUND: The risk of fragility fractures is high in kidney transplant recipients, and steroids are reportedly a major cause. Other drugs known to induce fragility fractures have been studied in the general population but not in kidney transplant recipients. Here, we investigated the association between exposure over time to drugs that can injure bone (namely vitamin K antagonists, insulin, loop diuretics, proton pump inhibitors, opioids, selective serotonin reuptake inhibitors, antiepileptics and benzodiazepines) and incident fractures and changes over time in T-scores in this population...
March 2023: Clinical Kidney Journal