journal
https://read.qxmd.com/read/37096012/riedel-s-thyroiditis-pitfalls-in-diagnosis-and-subsequent-complications
#21
R Pandev, M Khan, V Ratheesh
Riedel's thyroiditis is a rare disease of chronic inflammation with fibrotic infiltration of the thyroid gland and its surrounding vital structures. Due to its low incidence, there are often delays in diagnosis as it is commonly mistaken for other thyroid diseases. We report the case of a 34-year-old female patient who presented with a firm, enlarged mass in the neck, compression symptoms, and hypothyroidism. Lab tests showed elevated A-TG (thyroglobulin antibodies) and A-TPO (thyroid peroxidase antibodies) levels...
2023: Case Reports in Endocrinology
https://read.qxmd.com/read/37089262/thyrotoxicosis-after-covid-19-infection-with-a-delay-in-graves-disease-antibody-positivity
#22
Dennis C Boyle, Jamie A Mullally
Background and Objective . Mounting evidence implicates COVID-19 as a cause of thyroid dysfunction, including thyrotoxicosis due to both thyroiditis and Graves' disease (GD). In this report, we present a case of thyrotoxicosis following COVID-19 infection that was ultimately found to represent GD with significantly delayed diagnostic serum antibody positivity. Case Report . A 65-year-old woman with a history of uncomplicated COVID-19 infection one month prior, presented to the Emergency Department with exertional dyspnea and palpitations, and was found to be in atrial fibrillation with rapid ventricular response (AF with RVR)...
2023: Case Reports in Endocrinology
https://read.qxmd.com/read/36941974/a-case-of-iatrogenic-cushing-s-syndrome-following-use-of-an-over-the-counter-arthritis-supplement
#23
Colin Dunn, Joshua Amaya, Patrick Green
BACKGROUND: Iatrogenic Cushing's syndrome is commonly seen as a complication of chronic steroid use. While most often associated with the use of prescription oral steroids, rare cases result from unintentional steroid exposure. In particular, numerous complementary and alternative medicines have been found to contain steroids not previously known to users. Case Presentation . Here, we present a case of iatrogenic Cushing's syndrome caused by prolonged ingestion of dexamethasone found within an over-the-counter arthritis supplement called Artri King...
2023: Case Reports in Endocrinology
https://read.qxmd.com/read/36937651/sitosterolemia-a-case-report-and-a-concise-literature-review
#24
Moeber M Mahzari
BACKGROUND: Sitosterolemia is a relatively rare metabolism lipid disorder, with about 110 cases worldwide and only a few known cases from the Middle East. Sitosterolemia is characterized by excessive uptake of phytosterols and their deposition in various tissues, leading to complications. Mutations in the ABCG5 and ABCG8 genes are associated with pathological changes in sitosterolemia. Case Presentation . An adult patient from Saudi Arabia with dyslipidemia who did not respond to statin therapy...
2023: Case Reports in Endocrinology
https://read.qxmd.com/read/36895827/a-rare-observation-of-brachymetacarpia-and-brachymetatarsia-in-a-patient-with-primary-idiopathic-hypoparathyroidism
#25
Parackrama Karunathilake, Arun Rajaratnam, W K S Kularatne
Brachymetacarpia and brachymetatarsia are unique clinical entities associated with numerous rare conditions. Primary hypoparathyroidism is distinct from pseudohypoparathyroidism and pseudopseudohypoparathyroidism by lacking skeletal changes such as short metacarpals or metatarsals. Here, we present a case of a 64-year-old patient with brachymetacarpia and brachymetatarsia presented with hypocalcemic symptoms and signs, bilateral cataracts, and basal ganglia calcifications, subsequently diagnosed with idiopathic primary hypoparathyroidism...
2023: Case Reports in Endocrinology
https://read.qxmd.com/read/36890810/sodium-glucose-transport-protein-2-inhibitors-association-with-euglycemic-diabetic-ketoacidosis
#26
Caroline Wojtas, Alex P Rasarmos, Naja Naddaf
Diabetic ketoacidosis (DKA) is a life-threatening medical emergency that occurs in both type 1 and type 2 diabetes mellitus. Here, we describe the case of a 49 year-old male patient with type 2 diabetes mellitus who presented to the emergency department with complaints of epigastric abdominal pain and intractable vomiting. He had been on sodium-glucose transport protein 2 inhibitors (SGLT2i) for 7 months. Considering the clinical exam and lab findings with a glucose level of 229, a diagnosis of euglycemic DKA was made...
2023: Case Reports in Endocrinology
https://read.qxmd.com/read/36742443/giant-pheochromocytoma-diagnosis-confounded-by-amphetamine-use
#27
Shreya Amin, Matthew Gilbert, Kaitlyn Barrett
OBJECTIVE: Diagnosis of giant pheochromocytoma is difficult; patients often lack the classic triad and presence of gross biochemical positivity. At times, presence of sympathetic stimulant drugs can further complicate the clinical picture. Here, we present a case of giant "functional" pheochromocytoma with a history of amphetamine use. Case Description . 37-year-old female presented with a 1-day history of abdominal pain. CT abdomen identified a 12.5 cm heterogeneously enhancing left adrenal mass...
2023: Case Reports in Endocrinology
https://read.qxmd.com/read/36718481/topical-glucocorticoid-use-and-the-risk-of-posttransplant-diabetes
#28
Simon Bøtker, Henrik Birn, Lara Aygen Øzbay
Systemically administered glucocorticoids constitute an essential part of the immunosuppressive regimen for transplant recipients, yet their known risks of causing hyperglycemia or posttransplant diabetes require close monitoring and minimisation of use, when possible, to prevent detrimental effects on patient morbidity and graft survival. Topical glucocorticoids, on the other hand, are rarely considered to affect glucose metabolism and therefore seldomly monitored, despite their wide and in some cases, long-term use...
2023: Case Reports in Endocrinology
https://read.qxmd.com/read/36588628/bypass-oma-hypoglycemic-hyperinsulinemic-nesidioblastosis-after-gastric-bypass-surgery-a-case-report-and-review-of-the-literature
#29
Jessica Cao, Cindy Kim, Thatcher Huynh, Amanda Frugoli, Heidi Henson, Vera Valdez, Tricia Westhoff-Pankratz
This rare case vignette describes hypoglycemic, hyperinsulinemic nesidioblastosis in a female patient with prior Roux-en-Y gastric bypass. The patient presented with severe symptomatic hypoglycemia resistant to IV dextrose and diazoxide, requiring surgical resection. Traditional imaging found nonspecific findings, and biochemical analysis was inconsistent with insulinoma. A gallium-68 dotatate PET scan was utilized to successfully localize the tumor in the distal pancreas. She underwent laparoscopic resection of the distal pancreatic lesion with resolution of her symptoms and return to euglycemia...
2022: Case Reports in Endocrinology
https://read.qxmd.com/read/36588627/development-and-resolution-of-secondary-adrenal-insufficiency-after-an-intra-articular-steroid-injection
#30
Jia Wei Tan, Sachin K Majumdar
Corticosteroid injections are commonly indicated in inflammatory conditions involving the soft tissues, tendon sheaths, bursae, and joints. Local corticosteroids carry a lower risk of complications than systemic corticosteroid but may be systemically absorbed and subsequently suppress the hypothalamic-pituitary-adrenal (HPA) axis. This can cause secondary adrenal insufficiency (SAI) as well as iatrogenic Cushing's syndrome. We report a 78-year-old female who presented with nonspecific gastrointestinal symptoms after a recent intra-articular steroid injection in her shoulder...
2022: Case Reports in Endocrinology
https://read.qxmd.com/read/36518157/multifocal-multisystem-langerhans-cell-histiocytosis-involving-pituitary-masquerading-as-crohn-s-disease-a-case-report-and-review-of-the-literature
#31
Mohd Ashraf Ganie, Bhanu Malhotra, Manpreet Saini, Arshiya Dutta, Atul Sharma, Kim Vaiphie, Pinaki Dutta
Background/Objective . We present a case of Langerhans cell histiocytosis (LCH) with gastrointestinal involvement masquerading as inflammatory bowel disease (IBD) in a patient who initially had features of central diabetes insipidus (CDI). Case Report. A 19-year-old male presented at 14 years of age with central diabetes insipidus. He subsequently developed panhypopituitarism and sellar-suprasellar mass, the biopsy of which was inconclusive. Secondary causes for hypophysitis were ruled out. Five years later, he developed perianal pus discharging sinuses, positive ASCA, and sacroiliitis...
2022: Case Reports in Endocrinology
https://read.qxmd.com/read/36504598/spontaneous-adrenal-hemorrhage-with-mild-hypoadrenalism-in-a-patient-anticoagulated-with-apixaban-for-antiphospholipid-syndrome-a-case-report-and-literature-review
#32
Jia Wei Tan, Anant Shukla, Jiun-Ruey Hu, Sachin K Majumdar
BACKGROUND: Adrenal hemorrhage (AH) is a serious endocrine complication of antiphospholipid syndrome (APLS). Case Presentation . We report a 45-year-old man who presented with several deep venous thromboses and was initially treated with apixaban, who later developed bilateral AH. Laboratory findings were consistent with cortisol deficiency yet preserved aldosterone physiology. He was diagnosed with APLS and treated with warfarin. After 8 months of follow-up, he remained on cortisol replacement with no evidence of recovery...
2022: Case Reports in Endocrinology
https://read.qxmd.com/read/36465526/acute-sheehan-s-syndrome-presenting-with-hyponatremia-followed-by-a-spontaneous-pregnancy
#33
Maria M Pineyro, Leonardo Diaz, Macarena Guzzetti, Mariana Risso, Jimena Pereda
BACKGROUND: Acute Sheehan's syndrome is rare, as well as hyponatremia as its initial manifestation. In addition, spontaneous pregnancy in patients after Sheehan's syndrome is unusual. To our knowledge, no cases of spontaneous pregnancy after acute Sheehan's syndrome have been reported. We describe a case of Sheehan's syndrome that presented with acute hyponatremia and a spontaneous pregnancy. CASE: A 34-year-old female developed blood loss during delivery, which required a blood transfusion...
2022: Case Reports in Endocrinology
https://read.qxmd.com/read/36406870/thyroiditis-after-mrna-vaccination-for-covid-19
#34
Arunava Saha, Sanjita Chittimoju, Nitin Trivedi
BACKGROUND: SARS-CoV-2 has been known to cause multisystemic involvement, gaining entry through ACE-2 and TMPRSS2 receptors. COVID-19 vaccine-associated thyroiditis cases are now being reported. Case Report . Case 1 . A 36-year-old woman with a history of right hemithyroidectomy for a benign thyroid nodule, on a stable dose of levothyroxine with euthyroid labs, presented with progressively worsening left neck pain, episodic palpitations, and heat intolerance after the second dose of mRNA1273 (Moderna) vaccine...
2022: Case Reports in Endocrinology
https://read.qxmd.com/read/36387937/severe-hypothyroidism-and-large-goiter-due-to-iodine-deficiency-in-an-adolescent-male-in-the-united-states-a-case-report-and-review-of-the-literature
#35
Claire E Moore, Sabitha Sasidharan Pillai, Juliana Austin, Meghan E Fredette, Monica Serrano-Gonzalez
Acquired hypothyroidism due to iodine deficiency is extremely rare in the United States due to the introduction of table salt iodization in the 1920s (Leung et al., 2012). We present the case of an adolescent male with a history of mild autism spectrum disorder and an extremely restrictive diet who was found to have iodine deficiency as the etiology for his rapidly enlarging goiter and antibody-negative hypothyroidism. Thyroid-stimulating hormone (TSH) was 416  μ IU/mL (0.350-5.500  μ IU/mL), free thyroxine (T4) was <0...
2022: Case Reports in Endocrinology
https://read.qxmd.com/read/36339511/giant-parathyroid-tumor-parathyroid-adenoma-versus-parathyroid-carcinoma
#36
Farid Gossili, Allan Carlé, Trine B Andersen, Helle D Zacho
Parathyroid adenoma is the most common cause of primary hyperparathyroidism (PHPT). We present the preoperative detection of a giant parathyroid adenoma (GPA) using (99m Tc)-sestamibi parathyroid scintigraphy in a patient presenting with severely elevated parathyroid hormone, hypercalcemia, hypophosphatemia, and vitamin D insufficiency. The patient complained of cerebral symptoms and intermittent abdominal discomfort without constipation. After surgical removal of the hyperactive parathyroid gland and D vitamin supplementation, all blood tests were normalized...
2022: Case Reports in Endocrinology
https://read.qxmd.com/read/36304180/a-case-report-about-glycogenic-hepatopathy
#37
L Plaza Enriquez, N Konindala, H Yeh, P Khatiwada, M Sanchez Valenzuela, K Askari
INTRODUCTION: Glycogenic hepatopathy is a rare complication of uncontrolled diabetes mellitus that presents with hepatomegaly and transient elevation in serum aminotransferase enzymes. The underlying pathophysiology involves excessive accumulation of intrahepatic glycogen. Glycogenic hepatopathy is usually underdiagnosed because it is difficult to differentiate from other entities, such as the nonalcoholic fatty liver. The gold standard for diagnosis is liver biopsy. Glycogenic hepatopathy can be reversed by the achievement of adequate glycemic control...
2022: Case Reports in Endocrinology
https://read.qxmd.com/read/36248222/severe-hypophosphatemia-occurring-after-repeated-exposure-to-a-parenteral-iron-formulation
#38
Keerthana Haridas, Alice Yau
Hypophosphatemia is a less known complication of parenteral iron use, particularly after the use of certain iron formulations. We report the case of a young male with inflammatory bowel disease and iron deficiency anemia, who developed severe symptomatic hypophosphatemia after his third exposure to iron carboxymaltose with no evidence of the same occurring upon prior exposures to the compound. Investigations revealed serum phosphorous levels of 0.7 mg/dl, corrected serum calcium of 8-9.5 mg/dl, alkaline phosphatase of 50 U/L (38-126), 25 hydroxy vitamin D level of 40...
2022: Case Reports in Endocrinology
https://read.qxmd.com/read/36248221/functional-localization-of-adult-onset-idiopathic-nesidioblastosis
#39
Jess C Hercus, Pouneh Pasha, Sadiq Al Lawati, Peter Kim, Andre Mattman, Douglas Webber, David M Thompson
Nesidioblastosis is a rare pancreatic disorder involving enlarged beta cells throughout the pancreas, causing elevated insulin production. We present the case of a 53-year-old woman with the initial symptom of fasting hypoglycemia. No pancreatic lesions were indicated on computed tomography and magnetic resonance imaging scans, and an octreotide scan was negative for insulinoma. Selective arterial calcium stimulation (SACST) showed increased insulin production from the stimulation of 3 out of 5 arteries. The SACST results suggested a diagnosis of nesidioblastosis, which was confirmed by histopathology after a subtotal distal pancreatectomy...
2022: Case Reports in Endocrinology
https://read.qxmd.com/read/36225803/intravenous-iodinated-contrast-induced-thyrotoxic-periodic-paralysis-a-case-report
#40
S Alrushaid, T Alessa
Thyrotoxic periodic paralysis (TPP) is an entity that has been described in the literature as a transient, symmetrical, flaccid paralysis, mainly affecting the lower limbs of patients with a current or previous history of hyperthyroidism. In most cases, Graves' disease is the cause of hyperthyroidism. Contrast and iodine-induced TPP have been described in the literature, but only one case of intravenous contrast induced TPP has been reported. We report a case of TPP following administration of intravenous contrast for a computed tomography scan of the neck prior to lymph node excision...
2022: Case Reports in Endocrinology
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