journal
https://read.qxmd.com/read/38464360/mitochondrial-dysfunction-in-type-2-diabetes-a-neglected-path-to-skeletal-muscle-atrophy
#21
EDITORIAL
Jian-Jun Wu, Hui-Min Xian, Da-Wei Yang, Fan Yang
Over the course of several decades, robust research has firmly established the significance of mitochondrial pathology as a central contributor to the onset of skeletal muscle atrophy in individuals with diabetes. However, the specific intricacies governing this process remain elusive. Extensive evidence highlights that individuals with diabetes regularly confront the severe consequences of skeletal muscle degradation. Deciphering the sophisticated mechanisms at the core of this pathology requires a thorough and meticulous exploration into the nuanced factors intricately associated with mitochondrial dysfunction...
February 18, 2024: World Journal of Orthopedics
https://read.qxmd.com/read/38464359/review-and-update-on-the-management-of-triangular-fibrocartilage-complex-injuries-in-professional-athletes
#22
REVIEW
Valerio Pace, Francesco Bronzini, Giovanni Novello, Giuseppe Mosillo, Luca Braghiroli
Triangular fibrocartilage complex injuries are common in amateur and professional sports. These injuries are mainly caused by acute or chronic repetitive axial loads on the wrist, particularly on the ulnar side and in association with rotations or radial/ulnar deviations. In order to treat professional athletes, a detailed specific knowledge of the pathology is needed. Moreover, the clinician should fully understand the specific and unique environment and needs of the athletes, their priorities and goals, the type of sport, the time of the season, and the position played...
February 18, 2024: World Journal of Orthopedics
https://read.qxmd.com/read/38464358/high-rate-of-clinically-relevant-improvement-following-anatomical-total-shoulder-arthroplasty-for-glenohumeral-osteoarthritis
#23
JOURNAL ARTICLE
Marc Randall Kristensen Nyring, Bo Sanderhoff Olsen, Alexander Amundsen, Jeppe Vejlgaard Rasmussen
BACKGROUND: The minimal clinically important difference (MCID) is defined as the smallest meaningful change in a health domain that a patient would identify as important. Thus, an improvement that exceeds the MCID can be used to define a successful treatment for the individual patient. AIM: To quantify the rate of clinical improvement following anatomical total shoulder arthroplasty for glenohumeral osteoarthritis. METHODS: Patients were treated with the Global Unite total shoulder platform arthroplasty between March 2017 and February 2019 at Herlev and Gentofte Hospital, Denmark...
February 18, 2024: World Journal of Orthopedics
https://read.qxmd.com/read/38464357/academic-productivity-correlates-with-industry-earnings-in-foot-and-ankle-fellowship-programs-in-the-united-states-a-retrospective-analysis
#24
JOURNAL ARTICLE
Albert T Anastasio, Anthony N Baumann, Kempland C Walley, Kyle J Hitchman, Conor O'Neill, Jonathan Kaplan, Samuel B Adams
BACKGROUND: The study investigates the connection between academic productivity and industry earnings in foot and ankle orthopedic surgery fellowships. Utilizing metrics like the H-index and Open Payments Database (OPD) data, it addresses a gap in understanding the relationship between scholarly achievements and financial outcomes, providing a basis for further exploration in this specialized medical field. AIM: To elucidate the trends between academic productivity and industry earnings across foot and ankle orthopedic surgery fellowship programs in the United States...
February 18, 2024: World Journal of Orthopedics
https://read.qxmd.com/read/38464356/mid-term-outcomes-of-a-kinematically-designed-cruciate-retaining-total-knee-arthroplasty
#25
JOURNAL ARTICLE
Jonathan L Katzman, Akram A Habibi, Muhammad A Haider, Casey Cardillo, Ivan Fernandez-Madrid, Morteza Meftah, Ran Schwarzkopf
BACKGROUND: Advances in implant material and design have allowed for improvements in total knee arthroplasty (TKA) outcomes. A cruciate retaining (CR) TKA provides the least constraint of TKA designs by preserving the native posterior cruciate ligament. Limited research exists that has examined clinical outcomes or patient reported outcome measures (PROMs) of a large cohort of patients undergoing a CR TKA utilizing a kinematically designed implant. It was hypothesized that the studied CR Knee System would demonstrate favorable outcomes and a clinically significant improvement in pain and functional scores...
February 18, 2024: World Journal of Orthopedics
https://read.qxmd.com/read/38464355/meta-analysis-of-factors-influencing-anterior-knee-pain-after-total-knee-arthroplasty
#26
JOURNAL ARTICLE
Hui Feng, Ming-Li Feng, Jing-Bo Cheng, Xiang Zhang, Hai-Cheng Tao
BACKGROUND: Total knee arthroplasty (TKA) is a mature procedure recommended for correcting knee osteoarthritis deformity, relieving pain, and restoring normal biomechanics. Although TKA is a successful and cost-effective procedure, patient dissatisfaction is as high as 50%. Knee pain after TKA is a significant cause of patient dissatisfaction; the most common location for residual pain is the anterior region. Between 4% and 40% of patients have anterior knee pain (AKP). AIM: To investigate the effect of various TKA procedures on postoperative AKP...
February 18, 2024: World Journal of Orthopedics
https://read.qxmd.com/read/38464354/burden-of-routine-orthopedic-implant-removal-a-single-center-retrospective-study
#27
JOURNAL ARTICLE
Ammar K AlOmran, Nader Alosaimi, Ahmed A Alshaikhi, Omar M Bakhurji, Khalid J Alzahrani, Basil Ziyad Salloot, Tamim Omar Alabduladhem, Ahmed I AlMulhim, Arwa Alumran
BACKGROUND: Open reduction and internal fixation represent prevalent orthopedic procedures, sparking ongoing discourse over whether to retain or remove asymptomatic implants. Achieving consensus on this matter is paramount for orthopedic surgeons. This study aims to quantify the impact of routine implant removal on patients and healthcare facilities. A retrospective analysis of implant removal cases from 2016 to 2022 at King Fahad Hospital of the University (KFHU) was conducted and subjected to statistical scrutiny...
February 18, 2024: World Journal of Orthopedics
https://read.qxmd.com/read/38464353/limb-lengthening-and-reconstruction-society-orthopedic-surgeons-in-the-united-states-an-analysis-of-geographical-distribution-academic-leadership-and-demographic-characteristics
#28
JOURNAL ARTICLE
Amir Human Hoveidaei, Reza Niakan, Seyed Hossein Hosseini-Asl, Abijith Annasamudram, Janet D Conway
BACKGROUND: The Limb Lengthening and Reconstruction Society (LLRS) is a premier orthopedic specialty organization that promotes limb reconstruction for all ages. LLRS membership characteristics, however, are poorly reported. This study delineates orthopedic surgeon LLRS members' demographic traits, academic achievement, leadership attainment, and geographical distribution across the United States. AIM: To inform aspiring orthopedic professionals, as well as to promote growth and diversity in both the LLRS organization and overarching field...
February 18, 2024: World Journal of Orthopedics
https://read.qxmd.com/read/38464352/effect-of-ankle-versus-thigh-tourniquets-on-post-operative-pain-in-foot-and-ankle-surgery
#29
JOURNAL ARTICLE
Ashish Mishra, Ahmed Barakat, Jitendra Mangwani, Jakub Kazda, Sagar Tiwatane, Sana Mohammed Aamir Shaikh, Linzy Houchen-Wolloff, Vipul Kaushik
BACKGROUND: Tourniquets are commonly used in elective extremity orthopaedic surgery to reduce blood loss, improve visualization in the surgical field, and to potentially reduce surgical time. There is a lack of consensus in existing guidelines regarding the optimal tourniquet pressure, placement site, and duration of use. There is a paucity of data on the relationship between the site of a tourniquet and postoperative pain in foot and ankle surgery. AIM: To explore the relationship between tourniquet site and intensity of post-operative pain scores in patients undergoing elective foot and ankle surgery...
February 18, 2024: World Journal of Orthopedics
https://read.qxmd.com/read/38464351/assessment-of-the-effectiveness-of-weight-adjusted-antibiotic-administration-for-reduced-duration-in-surgical-prophylaxis-of-primary-hip-and-knee-arthroplasty
#30
JOURNAL ARTICLE
Tosan Okoro, Michael Wan, Takura Darlington Mukabeta, Ella Malev, Marketa Gross, Claudia Williams, Muhammad Manjra, Jan Herman Kuiper, John Murnaghan
BACKGROUND: Prophylactic antibiotics have significantly led to a reduction in the risk of post-operative surgical site infections (SSI) in orthopaedic surgery. The aim of using antibiotics for this purpose is to achieve serum and tissue drug levels that exceed, for the duration of the operation, the minimum inhibitory concentration of the likely organisms that are encountered. Prophylactic antibiotics reduce the rate of SSIs in lower limb arthroplasty from between 4% and 8% to between 1% and 3%...
February 18, 2024: World Journal of Orthopedics
https://read.qxmd.com/read/38464350/deep-learning-automation-of-radiographic-patterns-for-hallux-valgus-diagnosis
#31
EDITORIAL
Angela Hussain, Cadence Lee, Eric Hu, Farid Amirouche
Artificial intelligence (AI) and deep learning are becoming increasingly powerful tools in diagnostic and radiographic medicine. Deep learning has already been utilized for automated detection of pneumonia from chest radiographs, diabetic retinopathy, breast cancer, skin carcinoma classification, and metastatic lymphadenopathy detection, with diagnostic reliability akin to medical experts. In the World Journal of Orthopedics article, the authors apply an automated and AI-assisted technique to determine the hallux valgus angle (HVA) for assessing HV foot deformity...
February 18, 2024: World Journal of Orthopedics
https://read.qxmd.com/read/38464349/adenylate-cyclase-activates-the-camp-signalling-pathway-to-enhance-platelet-rich-plasma-treated-achilles-tendon-disease-a-theoretical-bioinformatics-based-study
#32
JOURNAL ARTICLE
Jing-Yi Sun, Cai Li, Feng-Ying Du
The effectiveness of platelet-rich plasma (PRP) for the treatment of Achilles tendon disorders still needs to be evaluated through a series of prospective studies, but genomic analysis can reveal the existence of complementary PRP treatment options. Based on the 96 platelet activation-related genes in the Kyoto Encyclopedia of Genes and Genomes (KEGG) database, we performed Gene Ontology functional enrichment analysis and KEGG enrichment analysis, pathway correlation analysis, and enrichment mapping to determine the enrichment results of the gene set enrichment analysis and found that the cAMP signalling pathway may be the key to enhancing the effectiveness of PRP treatment...
February 18, 2024: World Journal of Orthopedics
https://read.qxmd.com/read/38293265/association-between-serum-estradiol-level-and-appendicular-lean-mass-index-in-middle-aged-postmenopausal-women
#33
JOURNAL ARTICLE
Fang Jin, Yan-Fei Wang, Zhong-Xin Zhu
BACKGROUND: Previous studies investigating the association between loss of estrogen at menopause and skeletal muscle mass came to contradictory conclusions. AIM: To evaluate the association between serum estradiol level and appendicular lean mass index in middle-aged postmenopausal women using population-based data. METHODS: This study included 673 postmenopausal women, aged 40-59 years, from the National Health and Nutrition Examination Survey between 2013 and 2016...
January 18, 2024: World Journal of Orthopedics
https://read.qxmd.com/read/38293264/epidemiologic-investigation-of-pediatric-distal-humerus-fractures-an-american-insurance-claims-database-study
#34
JOURNAL ARTICLE
Kyle Jay Klahs, Jake E Dertinger, Grant T Mello, Kevin Thapa, Alexis B Sandler, E'Stephan J Jesus Garcia, Nata Parnes
BACKGROUND: Distal humerus elbow fractures are one of the most common traumatic fractures seen in pediatric patients and present as three main types: Supracondylar (SC), lateral condyle (LC), and medial epicondyle (ME) fractures. AIM: To evaluate the epidemiology of pediatric distal humerus fractures (SC, LC, and ME) from an American insurance claims database. METHODS: A retrospective review was performed on patients 17 years and younger with the ICD 9 and 10 codes for SC, LC and ME fractures based on the IBM Truven MarketScan® Commercial and IBM Truven MarketScan Medicare Supplemental databases...
January 18, 2024: World Journal of Orthopedics
https://read.qxmd.com/read/38293263/surgical-treatment-of-an-old-avulsion-fracture-of-the-ischial-tuberosity-and-ischial-ramus-a-case-report
#35
Zi-Ru Chen, Shi-Jie Liao, Fu-Chun Yang
BACKGROUND: Avulsion fracture of the ischial tuberosity is a relatively clinically rare type of trauma that is mainly incurred by adolescents during competitive sports activities. According to previous literature, the most commonly involved sports are soccer, sprinting, and gymnastics, in descending order. Dance-induced avulsion fracture of the ischial tuberosity and ischial ramus is extremely clinically rare. CASE SUMMARY: A case of a neglected avulsion fracture of the ischial tuberosity and ischial ramus was diagnosed in a young female dancer who complained of pain and restricted movement of her right hip...
January 18, 2024: World Journal of Orthopedics
https://read.qxmd.com/read/38293262/effective-time-correction-speed-and-termination-time-of-hemi-epiphysiodesis-in-children
#36
REVIEW
Jian-Fa Zeng, Yu-Yin Xie, Can Liu, Zhen-Qi Song, Zheng Xu, Zhong-Wen Tang, Jie Wen, Sheng Xiao
In children with asymmetric growth on the medial and lateral side of limbs, if there still remains growth potential, the guided growth technique of hemi-epiphysiodesis on one side of the epiphysis is recognized as a safe and effective method. However, when the hemi-epiphysiodesis start to correct the deformities, how many degrees could hemi-epiphysiodesis bring every month and when to remove the hemi-epiphysiodesis implant without rebound phenomenon are still on debate. This article reviews the current studies focus on the effective time, correction speed and termination time of hemi-epiphysiodesis...
January 18, 2024: World Journal of Orthopedics
https://read.qxmd.com/read/38293261/which-approach-of-total-hip-arthroplasty-is-the-best-efficacy-and-least-complication
#37
JOURNAL ARTICLE
Lertkong Nitiwarangkul, Natthapong Hongku, Oraluck Pattanaprateep, Sasivimol Rattanasiri, Patarawan Woratanarat, Ammarin Thakkinstian
BACKGROUND: Total hip arthroplasty is as an effective intervention to relieve pain and improve hip function. Approaches of the hip have been exhaustively explored about pros and cons. The efficacy and the complications of hip approaches remains inconclusive. This study conducted an umbrella review to systematically appraise previous meta-analysis (MAs) including conventional posterior approach (PA), and minimally invasive surgeries as the lateral approach (LA), direct anterior approach (DAA), 2-incisions method, mini-lateral approach and the newest technique direct superior approach (DSA) or supercapsular percutaneously-assisted total hip (SuperPath)...
January 18, 2024: World Journal of Orthopedics
https://read.qxmd.com/read/38293260/scoliocorrector-fatma-ui-for-correction-of-adolescent-idiopathic-scoliosis-development-effectivity-safety-and-functional-outcome
#38
Phedy Phedy, Ismail Hadisoebroto Dilogo, Wresti Indriatmi, Sugeng Supriadi, Marcel Prasetyo, Fitri Octaviana, Zairin Noor
BACKGROUND: Adolescent idiopathic scoliosis remains a major problem due to its high incidence, high risk, and high cost. One of the aims of the management in scoliosis is to correct the deformity. Many techniques are available to correct scoliosis deformity; however, they are all far from ideal to achieve three-dimensional correction in scoliosis. AIM: To develop a set of tools named Scoliocorrector Fatma-UI (SCFUI) to aid three-dimensional correction and to evaluate the efficacy, safety, and functional outcome...
January 18, 2024: World Journal of Orthopedics
https://read.qxmd.com/read/38293259/health-economics-for-intra-capsular-hip-fractures-undertaking-fixation
#39
JOURNAL ARTICLE
Anatole Wiik, Thomas Ashdown, Ian Holloway
BACKGROUND: Hip fracture is a common musculoskeletal injury in the elderly requiring surgery worldwide. The operative mainstay of intra-capsular hip fractures is arthroplasty with a smaller proportion for fixation. AIM: To determine the most beneficial method of fixation for patients with intra-capsular hip fractures. METHODS: A registered audit from 2012-2018 was conducted on all intra-capsular hip fractures treated with 2 commonly used fixation methods...
January 18, 2024: World Journal of Orthopedics
https://read.qxmd.com/read/38293258/mechanisms-of-shoulder-trauma-current-concepts
#40
REVIEW
Konstantinos Mastrantonakis, Athanasios Karvountzis, Christos K Yiannakopoulos, Georgios Kalinterakis
Acute traumatic injuries to the glenohumeral articulation are common. The types of injuries depend on age, muscle strength, bone density, and biomechanics of the traumatic event. Understanding the different mechanisms of trauma and how they affect the functional anatomical structures of the shoulder joint is crucial for the treatment of these lesions. Therefore, when clinicians have knowledge of these mechanisms they can accurately diagnose and treat shoulder pathology and predict distinct injury patterns. Here, we have described the fundamentals of the mechanisms of injury of the glenohumeral dislocation, dislocation with fracture of the humeral head, and the proximal humerus fracture...
January 18, 2024: World Journal of Orthopedics
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