Sif Bouju, Jes B Lauritzen, Alexandre Journé, Henrik L Jørgensen
INTRODUCTION: In orthopaedics, anterior cruciate ligament (ACL) reconstructions are among the most common surgical interventions. Two methods are preferably used: autografts from the hamstring tendon (HT) or patella tendon (PT). The purpose of this meta-analysis was to compare these two methods when returning to sports. METHODS: Eleven studies were included based on a literature search conducted in PubMed. The primary outcome was return to preinjury sport level in athletes...
June 19, 2024: Danish Medical Journal
Johan Skov Bundgaard, Uka Wilhjelm Geisler, Hanne Rex, Julie D Voss, Katharina M Main, Marianne Skov
INTRODUCTION: Greenlandic patients may be referred to Denmark for specialised diagnostics and treatment. The main collaborator for these activities is the National University Hospital, Rigshospitalet, Copenhagen. We aimed to investigate the referral pattern of Greenlandic paediatric patients to Rigshospitalet. METHODS: This was an observational quality assurance project comprising all Greenlandic patients below 18 years who received healthcare services at Rigshospitalet in the 2017-2021 period...
June 12, 2024: Danish Medical Journal
Mads Fiil Hjort, Arne Astrup
INTRODUCTION: Obesity adversely affects the health of the individual and impacts society through increased healthcare costs and lost workdays. Individuals in lower socioeconomic groups are more severely affected. Here, we examined people living with severe obesity and comorbidities across educational levels. METHODS: Individuals with a BMI ≥ 35 kg/m2 and aged ≥ 16 years from the Danish National Health Survey 2021 were categorised into five educational levels and according to their number of obesity-related comorbidities (0, 1, 2 and ≥ 3)...
June 12, 2024: Danish Medical Journal
Nora Olsen El Caidi, Jasmin Dam Lukoschewitz, Olav W Nielsen, Jens Hove, Ekim Seven, Ulrik Dixen, Frederik Grund, Morten Petersen, Nikolai Bang Foss, Johannes Grand
INTRODUCTION: Intravenous loop diuretics have been a key component in treating pulmonary oedema since the 1960s and have a Class 1 recommendation in the 2021 guidelines for acute heart failure (AHF). While the diuretic effect of loop diuretics is well established, it remains unclear how furosemide influences pulmonary congestion and cardiac filling pressures in the hyperacute phase before significant diuresis occurs. METHODS: This was a prospective study of adult patients with AHF and objective signs of pulmonary congestion admitted to the cardiac ward...
June 12, 2024: Danish Medical Journal
Haim Sompolinsky
This essay is dedicated to the memory of my father David Sompolinsky. As a medical student in Veterinary Medicine in Copenhagen, with the support of his professors and the Danish Resistance, David organised the rescue of 700 Danish Jews in October 1943, helping them escape Nazi persecution and find safety in Sweden.
May 27, 2024: Danish Medical Journal
Emilia Colding Ofverlind, Jesper Bille, Thure Filskov Overvad, Per Brønnum Nielsen, Ida Ehlers Albertsen
INTRODUCTION: Healthcare databases are a valuable source for epidemiological research in obstructive sleep apnoea, but accurately registered diagnoses are pivotal in contributing quality evidence. We examined positive predictive values (PPV) of the International Classification of Diseases, tenth version (ICD-10) diagnosis for "obstructive sleep apnoea" and "sleep apnoea" in the Danish National Patient Register. METHODS: Using the Danish National Patient Registry, we randomly sampled 100 patients from the North Denmark Region diagnosed with "obstructive sleep apnoea" (ICD-10 code DG4732) and 100 patients diagnosed with "sleep apnoea" (DG473*) during the year 2020...
May 13, 2024: Danish Medical Journal
Sarah Sofie Wadland, Lars Simon Rasmussen, Matias Vested
INTRODUCTION: The effect of neuromuscular blocking agents may be reversed by administration of neostigmine, when two twitches are present using train-of-four (TOF) stimulation. However, in elderly patients, limited data are available about when to administer neostigmine. We hypothesised that time to two twitches after TOF (TOF-2) was shorter after rocuronium 0.6 mg/kg than after rocuronium 0.9 mg/kg. Also, we hypothesised that time to TOF-2 would be shorter after rocuronium 0.3 mg/kg than after rocuronium 0...
May 13, 2024: Danish Medical Journal
Stine Horskær Madsen, Marie Louise Jespersen, Steen Joop Bonnema, Lars Rolighed, Kristina Zøylner Swan
INTRODUCTION: The Bethesda System for Reporting Thyroid Cytopathology (BSRTC) is used to categorise thyroid fine-needle aspiration (FNA). The aim of this study was to validate the BSRTC in a consecutive cohort and to evaluate the derived management in terms of performing repeat FNA or thyroid surgery. METHODS: Results of thyroid FNAs assessed at the Department of Pathology, Aarhus University Hospital, in the period 2016-2019 were retrieved from The Danish Pathology Registry...
May 13, 2024: Danish Medical Journal
Victoria Holten Springborg, Julie Milbak, Sissil Egge, Jane Marie Bendix, Nanna Vinterberg, Ida LA Ammitzbøll, Claus Aj Jensen, Jens Bryde Axelsson, Ellen Christine Leth Løkkegaard, Line Rode, Tine Dalsgaard Clausen
INTRODUCTION: We aimed to investigate the prevalence of SARS-CoV-2 infection and SARS-CoV-2 antibodies in parturient women and their newborns during the first Danish COVID-19 wave and to identify associations with maternal background characteristics, self-reported symptoms, and pregnancy outcomes. METHODS: In a single-centre, prospective cohort study from Denmark, we invited 1,883 women with singleton pregnancies giving live birth from 25 May 2020 to 2 November 2020...
May 1, 2024: Danish Medical Journal
Josefine Maria Bruun, Pernille Andreassen, Louise Elkjær Fløe, Jesper Grau Eriksen, Poul Videbech, Søren Paaske Johnsen, Mette Asbjoern JohnNeergaardsen
INTRODUCTION: Cancer trajectories among patients with pre-existing severe mental disorders (SMD) are challenging and these pateints' prognosis is poor. This study aimed at exploring barriers in cancer trajectories among patients with pre-existing SMD as experienced by Danish healthcare professionals. METHODS: Semi-structured interviews were conducted with healthcare professionals who were sampled by purposive sampling. Data were analysed using inductive qualitative content analysis...
April 23, 2024: Danish Medical Journal
Oliver Nørholm Kempf, Thora Wesenberg Helt, Klaus Birkelund Johansen, Charlotte Rittig, Louise Lundby-Christensen, Marianne Sjølin Frederiksen, Pernille Mathiesen, Malene Boas, Preben Berg Nielsen, Annie Ellermann, Klaus Børch, Jens Jakob Petersen, Thomas Houmann Petersen, Cæcilie Trier Sønderskov, Jesper Andersen, Rasmus Gaardskær Nielsen, Eva Mosfeldt Jeppesen, Vibeke Brix Christensen
INTRODUCTION: To assess the effect of long-term isolation on the mental state of Danish youth. This study aimed to investigate trends in paracetamol overdoses among people under 18 years of age in Denmark during Covid-19 restrictions as an indicator of mental health. METHODS: All patients under the age of 18 years presenting with paracetamol overdose at one of the 18 paediatric departments in Denmark from 2016 to 2021 were included. They were identified in all Danish hospital databases using specific diagnostic codes...
April 16, 2024: Danish Medical Journal
Lars Vedel Kessing, Ellen Margrethe Christensen, Sarah Krarup Krarup, Natacha Kyster, Lykke Pedersen, Christian Legind, Line Hansen, Birgitte Vejstrup, Maria Faurholt-Jepsen, Lone Baandrup, Ulla Knorr
Current evidence for pharmacological treatment of mania during hospitalisation is insufficient as there are no larger well-designed randomised trials of comparative medical treatments of mania during inpatient stays. Moreover, there is considerable variation in pharmacological medication in clinical practice during hospitalisation for mania. Based on a hospital data overview, a systematic search of the literature and a three-day consensus meeting, this narrative review proposed an algorithm for optimised pharmacological treatment of mania during hospitalisation and its subsequent scientific evaluation...
April 11, 2024: Danish Medical Journal
Rasmus Elsoe, Rikke Thorninger, Rasmus Severinsen, Jens-Christian Beuke, Rikke Serritslev, Steffen Skov Jensen, Morten Kjerri Rasmussen, Peter Szephalmi, Juozas Petruskevicius, Jeppe Barckman, Niels Henrik Bruun, Peter Larsen
INTRODUCTION: Following surgical management of patella fractures, patients commonly report pain; difficulties with weight-bearing tasks such as walking, running and climbing stairs; and restrictions in quality of life. Recently, a locking plate system for surgical management of patella fractures has been introduced. To date, no studies have compared standard treatment with tension band wiring with locking plate fixation in a randomised study design. We aim to compare the one-year patient-reported Knee Injury and Osteoarthritis Outcome subscale scores (KOOS5-subscales) after standard care tension band fixation with locking plate fixation for patients with patella fractures...
April 10, 2024: Danish Medical Journal
Lene Dahl Siggaard, Henrik Jacobsen, Dan Dupont Hougaard, Morten Høgsbro
INTRODUCTION: Capacity constraints in Danish hearing healthcare may lead to diagnostic delays and repetitive pre-treatment audiological exams for hearing-impaired patients. This study investigated the effectiveness of remote ear-nose-throat (ENT) specialist assessments (RESA) for complicated hearing loss, comparing the accuracy of private ENT specialists and medical audiologists. METHODS: RESA screening accuracy was determined for four ENT specialists, individually and as subspecialised groups...
March 15, 2024: Danish Medical Journal
Ditte Georgina Zhang, Jawad Ahmad Zahid, Noor Al-Huda Hadi, Simon Francis Thomsen
INTRODUCTION: Pre-graduate research is popular among medical students. Concerns about time constraints and lack of mentorship have been raised in international studies. The extent to which these issues affect Danish medical students remains unclear. We therefore aimed to assess the conditions and outcomes of pre-graduate research among medical students from the University of Copenhagen. METHODS: A descriptive, cross-sectional, questionnaire-based survey on experiences from pre-graduate research was distributed to medical students and recently graduated medical doctors from the University of Copenhagen who had engaged in full-time pre-graduate research...
March 8, 2024: Danish Medical Journal
Carolina Maria Helena Hilton, Jakob Foghsgaard, Tejs Klug, Lars Morsø
INTRODUCTION: Complications and recurrence within benign salivary gland surgery are not systematically registered in Denmark. Patient-reported outcome measures are increasingly included in clinical and health policy decision-making, and therefore it is crucial that this type of data is valid. A patient-reported questionnaire regarding outcome after benign parotid gland surgery has been developed and implemented in a national German database. We aimed to translate the Parotidectomy Outcome Inventory 8 (POI-8) into Danish and validate it...
March 8, 2024: Danish Medical Journal
Mia Nielsen, Mette Midttun
INTRODUCTION: Cellulitis is a common infection, especially among the elderly, and compression therapy is often recommended to reduce acute oedema and pain. A previous study showed that compression therapy led to a lower incidence of recurrent cellulitis in lower extremities in patients with chronic oedema. The aim of this study was to describe clinical characteristics of patients with cellulitis. METHODS: This was a retrospective descriptive study reviewing medical records and medicine registrations in patients ≥ 18 years with cellulitis...
February 29, 2024: Danish Medical Journal
Gilbert Moatshe, Lars Engebretsen
Knee dislocations are complex and devastating injuries that are potentially limb threatening. A high level of suspicion is required to diagnose and treat these injuries properly and timely because some of the knee dislocations spontaneously reduce, and the seriousness of the injury might not be appreciated early. Early diagnosis of concomitant vascular injuries is imperative to avoid limb loss because the risk of amputation is high when diagnosis and timely intervention are delayed. It is recommended that serial ankle-brachial index (ABI) be performed in all patients with suspected knee dislocation...
February 26, 2024: Danish Medical Journal
Emma Melchiorsen, Niels Dieter Rck, Jens Lauritsen
INTRODUCTION: This retrospective cohort study aimed to examine whether implementing mandatory referral changed the composition of patients visiting the Accident and Emergency (A and E) Department in relation to severity, demographics and activity at injury. METHODS: Patients visiting the A and E Department at Odense University Hospital, Denmark, in 2008-2019, were divided into three time periods: before (four years before any changes in the operation of the A and E), transition period (the four years during which mandatory referral and the centralised emergency medical service were implemented) and after (the four years after these changes had been implemented)...
February 15, 2024: Danish Medical Journal
Phillip Kaasgaard Sperling, Nicolai Launa, Arash Ghaffari, Helle Rømer, Maibrit Pape B Sørensen, Ole Rahbek, Søren Kold, Jannie Bisgaard
INTRODUCTION: Continuous peripheral nerve blocks (cPNBs) have shown favourable post-operative pain control results but may be associated with a risk for long-term neurological complications. This study sought to examine factors associated with persistent post-operative pain and potential neuropathy after orthopaedic lower-limb surgery with the use of post-operative cPNB. METHODS: Patients who underwent lower limb orthopaedic procedures with cPNBs between November 2021 to May 2022 were included...
February 15, 2024: Danish Medical Journal
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