journal
https://read.qxmd.com/read/37632245/in-chronic-spontaneous-urticaria-ige-and-c-reactive-protein-are-linked-to-distinct-micrornas-and-interleukin-31
#1
JOURNAL ARTICLE
Ozge Sevil Karstarli Bakay, Betül Demir, Demet Cicek, Deniz Erol, Zulal Aşçı Toraman, Yunus Gural, Marcus Maurer
BACKGROUND: Chronic spontaneous urticaria (CSU) is a common and disabling disease. Assessments of IgE and C-reactive protein (CRP) are recommended in the diagnostic work-up, but the role and clinical relevance of these biomarkers are not well characterized. Moreover, it remains unknown if elevated levels of IgE or CRP are linked to CSU microRNA (miRNA) signatures or interleukin 31 (IL-31). METHODS: We measured IgE and CRP serum levels in 47 CSU patients (and 45 healthy controls) and determined CSU disease activity using the urticaria activity score (UAS7)...
August 2023: Clinical and Translational Allergy
https://read.qxmd.com/read/37632244/effect-of-infant-viral-respiratory-disease-on-childhood-asthma-in-a-non-industrialized-setting
#2
JOURNAL ARTICLE
Jessica Atwell, Martha Chico, Maritza Vaca, Andrea Arévalo-Cortes, Ruth Karron, Philip J Cooper
BACKGROUND: There are limited data from non-industrialized settings on the effects of early life viral respiratory disease on childhood respiratory illness. We followed a birth cohort in tropical Ecuador to understand how early viral respiratory disease, in the context of exposures affecting airway inflammation including ascariasis, affect wheezing illness, asthma, and rhinoconjunctivitis in later childhood. METHODS: A surveillance cohort nested within a birth cohort was monitored for respiratory infections during the first 2 years in rural Ecuador and followed for 8 years for the development of wheeze and rhinoconjunctivitis...
August 2023: Clinical and Translational Allergy
https://read.qxmd.com/read/37632243/sensitization-patterns-to-cat-molecular-allergens-in-subjects-with-allergic-sensitization-to-cat-dander
#3
JOURNAL ARTICLE
Saliha Selin Özuygur Ermis, Aram Norouzi, Magnus P Borres, Rani Basna, Linda Ekerljung, Carina Malmhäll, Emma Goksör, Göran Wennergren, Madeleine Rådinger, Jan Lötvall, Hannu Kankaanranta, Bright I Nwaru
BACKGROUND: The use of molecular allergology has increasingly become common in the diagnosis and management of allergic diseases. However, there is still a lack of data on cat molecular allergens in adults. Therefore, we aimed to uncover the sensitization patterns to cat molecular allergens. METHODS: Participants were recruited from the West Asthma Sweden Study, a population-based study enriched with asthma subjects aged 16-75 years. Of 1872, 361 individuals were positive for cat dander immunoglobulin E and were further analysed for cat molecular allergens (Fel d 1/2/4/7)...
August 2023: Clinical and Translational Allergy
https://read.qxmd.com/read/37632242/risk-factors-of-nsaid-exacerbated-respiratory-disease-a%C3%A2-population-based-study
#4
JOURNAL ARTICLE
Alma Helevä, Aada Murtomäki, Heini Huhtala, Jean Bousquet, Annika Luukkainen, Jussi Karjalainen, Riikka Lemmetyinen, Jari Haukka, Paulus Torkki, Mikko Nuutinen, Sanna Toppila-Salmi
BACKGROUND: Asthma with NSAID-exacerbated respiratory disease (NERD) is associated with uncontrolled or severe asthma. NERD patients are more prone to severe allergic reactions and their asthma exacerbations lead to hospitalisations twice as often compared to patients with non-NERD-asthma. NERD patients are prone to recurrent nasal polyposis requiring frequent endoscopic sinus surgeries. However, the early risk factors of NERD are not fully understood. The aim was to identify risk factors of NERD among patients with adult-onset asthma...
August 2023: Clinical and Translational Allergy
https://read.qxmd.com/read/37632241/sensitization-patterns-to-poaceae-pollen-indicates-a-hierarchy-in-allergens-and-a-lead-of-tropical-grasses
#5
JOURNAL ARTICLE
Victoria Rodinkova, Serhii Yuriev, Vitalii Mokin, Olena Sharikadze, Yevhenii Kryzhanovskyi, Lilia Kremenska, Olha Kaminska, Andrii Kurchenko
BACKGROUND: The allergenicity of pollen of Poaceae family members is a well-known and confirmed fact. Using the data of component-resolved molecular diagnostics of allergy, we set a goal to establish the population and individual characteristics of sensitization to grass pollen and assess the patterns of its development. METHODS: Multiplex allergy Alex2 test results of 20,033 patients were used. In addition to descriptive statistics to uncover traits of the sensitized population, statistical inference was utilized to establish the conditional probability of sensitisation, the nature of links between allergens, and the most frequent combinations of allergens in individual patient profiles...
August 2023: Clinical and Translational Allergy
https://read.qxmd.com/read/37632240/anaphylaxis-management-in-a-french-pediatric-emergency-department-lessons-from-the-ana-ped-study
#6
JOURNAL ARTICLE
Evangéline Clark, Luciana Kase Tanno, Tram Vo, Brigitte Blanc, Pascal Demoly, Davide Caimmi
BACKGROUND: Anaphylaxis is a serious systemic hypersensitivity reaction that requires immediate recognition and prompt administration of epinephrine/adrenaline. The present study aimed to assess the appropriateness of epinephrine/adrenaline use in children identified as allergic by physicians in the emergency department (ED) at the time of the reaction, and to identify factors that are possibly associated with epinephrine/adrenaline administration, auto-injector prescription, and further referral to an allergist...
August 2023: Clinical and Translational Allergy
https://read.qxmd.com/read/37488741/pollen-grading-prediction-scale-for-patients-with-artemisia-pollen-allergy-in-china-a-3-day-moving-predictive-model
#7
JOURNAL ARTICLE
Zhaoyin Yin, Yuhui Ouyang, Bing Dang, Luo Zhang
BACKGROUND: Artemisia pollen is the most prevalent outdoor aeroallergen causing respiratory allergies in Beijing, China. Pollen allergen concentrations have a direct impact on the quality of life of those suffering from allergies. Artemisia pollen deposition grading predictions can provide early warning for the protection and treatment of patients as well as provide a scientific basis for allergen specific clinical immunotherapy. OBJECTIVE: To develop a model of Artemisia pollen grading to predict development in patients with pollen allergy...
July 2023: Clinical and Translational Allergy
https://read.qxmd.com/read/37488740/k-means-cluster-analysis-of-characteristic-patterns-of-allergen-in-different-ages-real-life-study
#8
JOURNAL ARTICLE
Lei Zhao, Jie Fang, Yong Ji, Yingying Zhang, Xin Zhou, Junfeng Yin, Min Zhang, Wuping Bao
BACKGROUND: Atopy varies in people of different ages owing to different physical conditions and exposure to allergens. We aimed to cluster ages based on atopic severity using K-means cluster analysis and identify atopic incidence, severity, as well as the association among peripheral eosinophils, IgE and sensitisation. METHODS: Consecutive patients (n = 7654) with allergic symptoms and undergoing allergen-specific IgE tests were included from 2013 to 2017...
July 2023: Clinical and Translational Allergy
https://read.qxmd.com/read/37488739/patterns-of-aeroallergen-sensitization-in-asthma-patients-identified-by-latent-class-analysis-a-cross-sectional-study-in-china
#9
JOURNAL ARTICLE
Jiale Zhang, Wenting Luo, Guoping Li, Huali Ren, Jie Su, Jianxin Sun, Ruifen Zhong, Siqin Wang, Zhen'an Li, Yan Zhao, Huashou Ke, Ting Chen, Chun Xv, Zhenglin Chang, Liting Wu, Xianhui Zheng, Miaoyuan Xv, Qingyuan Ye, Chuangli Hao, Baoqing Sun
BACKGROUND: This cross-sectional study aimed to identify latent sensitization profiles of asthma patients in mainland China, unveiling the association between regional differences and sensitization patterns. METHODS: 1056 asthma participants from 10 medical centers divided into eastern and western cohorts were clustered into four individual sensitization patterns, respectively, by using an unsupervised statistical modeling method, latent class analysis (LCA), based on the levels of 12 aeroallergens specific IgE reactivities...
July 2023: Clinical and Translational Allergy
https://read.qxmd.com/read/37488738/genetic-differences-according-to-onset-age-and-lung-function-in-asthma-a-cluster-analysis
#10
JOURNAL ARTICLE
Han-Kyul Kim, Ji-One Kang, Ji Eun Lim, Tae-Woong Ha, Hae Un Jung, Won Jun Lee, Dong Jun Kim, Eun Ju Baek, Ian M Adcock, Kian Fan Chung, Tae-Bum Kim, Bermseok Oh
BACKGROUND: The extent of differences between genetic risks associated with various asthma subtypes is still unknown. To better understand the heterogeneity of asthma, we employed an unsupervised method to identify genetic variants specifically associated with asthma subtypes. Our goal was to gain insight into the genetic basis of asthma. METHODS: In this study, we utilized the UK Biobank dataset to select asthma patients (All asthma, n = 50,517) and controls (n = 283,410)...
July 2023: Clinical and Translational Allergy
https://read.qxmd.com/read/37488737/in-chronic-spontaneous-urticaria-soluble-fc%C3%AE%C2%B5ri-is-elevated-and-linked-to-atopy-and-chronic-inducible-urticaria
#11
LETTER
Sherezade Moñino-Romero, Pavel Kolkhir, Zsolt Szépfalusi, Nicole Schoepke, Martin Metz, Riccardo Asero, Marta Ferrer, Ana Gimenez-Arnau, Clive E H Grattan, Thilo Jakob, George N Konstantinou, Ulrike Raap, Petra Staubach, Ke Zhang, Carsten Bindslev-Jensen, Alvaro Daschner, Tamar Kinaciyan, Michael Makris, Nadine Marrouche, Peter Schmid-Grendelmeier, Gordon Sussman, Elias Toubi, Marcus Maurer, Sabine Altrichter
No abstract text is available yet for this article.
July 2023: Clinical and Translational Allergy
https://read.qxmd.com/read/37488736/efficacy-of-probiotics-in-pediatric-atopic-dermatitis-a%C3%A2-systematic-review-and-meta-analysis
#12
REVIEW
Xiali Xue, Xinwei Yang, Xiubo Shi, Zhongyi Deng
BACKGROUND: Atopic dermatitis (AD) is a prevailing skin disease in childhood. Several studies have appraised probiotics as a strategy for treating AD. We aimed to assess the validity of probiotics in the treatment of AD in children. METHODS: We systematically searched the PubMed/MEDLINE, Embase, Scopus, EBSCO, Web of Science and Cochrane library databases for randomized controlled trials (RCTs) that assessed the effect of probiotic treatment on SCORAD value in pediatric patients with AD compared with a placebo group between 1 January 2010 and 1 January 2023...
July 2023: Clinical and Translational Allergy
https://read.qxmd.com/read/37488735/hospital-oral-food-challenge-tests-in-the-coronavirus-disease-2019-pandemic-a-nationwide-survey
#13
LETTER
Noriyuki Yanagida, Chizuko Sugizaki, Sakura Sato, Motohiro Ebisawa
No abstract text is available yet for this article.
July 2023: Clinical and Translational Allergy
https://read.qxmd.com/read/37488734/the-holo-beta-lactoglobulin-lozenge-reduces-symptoms-in-cat-allergy-evaluation-in-an-allergen-exposure-chamber-and-by-titrated-nasal-allergen-challenge
#14
JOURNAL ARTICLE
Karl-Christian Bergmann, Jennifer Raab, Anke Graessel, Thomas Zwingers, Sylvia Becker, Sebastian Kugler, Torsten Zuberbier, Franziska Roth-Walter, Matthias F Kramer, Erika Jensen-Jarolim
BACKGROUND: The allergists´ tool box in cat allergy management is limited. Clinical studies have shown that holo beta-lactoglobulin (holoBLG) can restore micronutritional deficits in atopic immune cells and alleviate allergic symptoms in a completely allergen-nonspecific manner. With this study, we aimed to provide proof of principle in cat allergy. METHODS: A novel challenge protocol for cat allergy in a standardized ECARF allergen exposure chamber (AEC) was developed...
July 2023: Clinical and Translational Allergy
https://read.qxmd.com/read/37488733/enhanced-thrombin-generation-potential-and-endothelial-dysfunction-in-chronic-spontaneous-urticaria
#15
LETTER
Katie Ridge, Helen Fogarty, Dearbhla Doherty, Mary Byrne, Cliona O'Farrelly, James S O'Donnell, Niall Conlon
No abstract text is available yet for this article.
July 2023: Clinical and Translational Allergy
https://read.qxmd.com/read/37488732/cluster-subcutaneous-allergen-immunotherapy-as-a-sustainable-practice-towards-net-zero-healthcare
#16
LETTER
Alicia Domínguez Estirado, Inmaculada Sánchez-Machín, Paloma Poza-Guedes, Ruperto González-Pérez
No abstract text is available yet for this article.
July 2023: Clinical and Translational Allergy
https://read.qxmd.com/read/37488731/charcot-leyden-crystals-in-tissues
#17
LETTER
Tomoko Sasaki, Isao Suzaki, Shigeharu Ueki
No abstract text is available yet for this article.
July 2023: Clinical and Translational Allergy
https://read.qxmd.com/read/37488730/primary-care-as-a-setting-for-introducing-milk-using-the-milk-ladder-in-children-with-ige-mediated-cow-s-milk-protein-allergy
#18
LETTER
Caoimhe Cronin, Anne Marie McGinley, Laura Flores, Anne McKiernan, Roberto Velasco, Jonathan O'B Hourihane, Juan Trujillo
No abstract text is available yet for this article.
July 2023: Clinical and Translational Allergy
https://read.qxmd.com/read/37488729/call-for-morphological-detection-of-charcot-leyden-crystals-in-tissue
#19
LETTER
Yurong Bai, Wenyi Chen, Weifeng Kong, Xin Luo, Jingyuan Chen, Xinyue Wang, Qingwu Wu, Jianning Chen, Qintai Yang, Yana Zhang
No abstract text is available yet for this article.
July 2023: Clinical and Translational Allergy
https://read.qxmd.com/read/37488728/barrier-forming-drug-free-nasal-spray-reduces-allergic-symptoms-induced-by-house-dust-mite-allergen
#20
JOURNAL ARTICLE
Patricia Couroux, Nicole Grosse, Anne Marie Salapatek, Yasmeen Goyal, Oliver Pfaar, Ilja P Hohenfeld
BACKGROUND: House Dust Mite (HDM) is the most common indoor allergen triggering allergic symptoms. First-line pharmacotherapy treatment is recommended in international guidelines, while the avoidance of allergens represents a still unmet guideline principle. AM-301 is a new non-pharmacological nasal spray that creates a protective gel-like barrier on the nasal mucosa, preventing the contact with the allergens. METHODS: This randomized, open-label, 3-period crossover study assessed the efficacy and safety of AM-301...
July 2023: Clinical and Translational Allergy
journal
journal
43899
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.