journal
Journals Human Vaccines & Immunotherape...

Human Vaccines & Immunotherapeutics

https://read.qxmd.com/read/38619081/pattern-of-multiple-human-papillomavirus-infection-and-type-competition-an-analysis-in-healthy-chinese-women-aged-18-45-years
#1
JOURNAL ARTICLE
Yingying Su, Tingquan Zheng, Zhaofeng Bi, Xinhua Jia, Yufei Li, Xuefeng Kuang, Yuan Yang, Qi Chen, Hongyan Lin, Yue Huang, Shoujie Huang, Youlin Qiao, Ting Wu, Jun Zhang, Ningshao Xia
To assess the pattern of multiple human papillomavirus infection to predict the type replacement postvaccination. A total of 7372 women aged 18-45y from a phase III trial of an Escherichia coli -produced HPV-16/18 vaccine were analyzed at enrollment visit before vaccination. Hierarchical multilevel logistic regression was used to evaluate HPV vaccine type and nonvaccine-type interactions with age as a covariate. Binary logistic regression was construed to compare multiple infections with single infections to explore the impact of multiple-type infections on the risk of cervical disease...
December 31, 2024: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/38619079/seasonal-influenza-vaccine-performance-and-the-potential-benefits-of-mrna-vaccines
#2
REVIEW
Colin A Russell, Ron A M Fouchier, Parinaz Ghaswalla, Yoonyoung Park, Nevena Vicic, Jintanat Ananworanich, Raffael Nachbagauer, Deborah Rudin
Influenza remains a public health threat, partly due to suboptimal effectiveness of vaccines. One factor impacting vaccine effectiveness is strain mismatch, occurring when vaccines no longer match circulating strains due to antigenic drift or the incorporation of inadvertent (eg, egg-adaptive) mutations during vaccine manufacturing. In this review, we summarize the evidence for antigenic drift of circulating viruses and/or egg-adaptive mutations occurring in vaccine strains during the 2011-2020 influenza seasons...
December 31, 2024: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/38619056/acceptance-and-willingness-to-pay-for-dtap-hbv-ipv-hib-hexavalent-vaccine-among-parents-a-cross-sectional-survey-in-china
#3
JOURNAL ARTICLE
Aodi Huang, Xia Xu, Lin Tang, Lifang Huang, Jun Li, Xue Zhang, Jiajie Liu, Yang Zhou, Bingling Zhang, Lei Wang, Qian Zhang, Zemei Zhou, Yu Wang, Xiaoqi Wang, Qianqian Liu, Siyu Liu, Zundong Yin, Fuzhen Wang
DTaP-HBV-IPV-Hib hexavalent vaccine has been used in high-income countries for many years to prevent diphtheria, tetanus, pertussis, hepatitis B, poliomyelitis, and invasive Haemophilus influenzae type b disease. Currently, no hexavalent vaccines have been approved for use in China. Evidence of parental acceptance and interest in hexavalent vaccines can help policy makers and manufacturers make decisions about entering the vaccine market and the immunization program in China. We measured parental acceptance and willingness-to-pay (WTP) for a hexavalent vaccine to provide such evidence...
December 31, 2024: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/38608171/development-and-validation-of-a-6-plex-luminex-based-assay-for-measuring-human-serum-antibodies-to-group-b-streptococcus-capsular-polysaccharides
#4
JOURNAL ARTICLE
Michelle A Gaylord, Melissa Larrier, Donna Giordano-Schmidt, Christopher D Grube, Suddham Singh, Ha H Nguyen, Andrew McKeen, Charles Y Tan, Annaliesa S Anderson, Warren V Kalina, Danka Pavliakova, Peter C Giardina
Six serotypes (Ia, Ib, II, III, IV, and V) cause nearly all group B streptococcal (GBS) disease globally. Capsular polysaccharide (CPS) conjugate vaccines aim to prevent GBS disease, however, licensure of a vaccine would depend on a standardized serological assay for measuring anti-CPS IgG responses. A multiplex direct Luminex-based immunoassay (dLIA) has been developed to simultaneously measure the concentration of serum IgG specific for the six prevalent GBS CPS serotypes. Assay validation was performed using serum samples obtained from human subjects vaccinated with an investigational 6-valent GBS CPS conjugate vaccine...
December 31, 2024: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/38608170/interlaboratory-comparison-of-a-multiplex-immunoassay-that-measures-human-serum-igg-antibodies-against-six-group-b-streptococcus-polysaccharides
#5
JOURNAL ARTICLE
Kirsty Le Doare, Michelle A Gaylord, Annaliesa S Anderson, Nick Andrews, Carol J Baker, Shanna Bolcen, Arif Felek, Peter C Giardina, Christopher D Grube, Tom Hall, Bassam Hallis, Alane Izu, Shabir A Madhi, Pete Maniatis, Mary Matheson, Fatme Mawas, Andrew McKeen, Julia Rhodes, Bailey Alston, Palak Patel, Stephanie Schrag, Raphael Simon, Charles Y Tan, Stephen Taylor, Gaurav Kwatra, Andrew Gorringe
Measurement of IgG antibodies against group B streptococcus (GBS) capsular polysaccharide (CPS) by use of a standardized and internationally accepted multiplex immunoassay is important for the evaluation of candidate maternal GBS vaccines in order to compare results across studies. A standardized assay is also required if serocorrelates of protection against invasive GBS disease are to be established in infant sera for the six predominant GBS serotypes since it would permit the comparison of results across the six serotypes...
December 31, 2024: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/38606820/determinants-of-immunization-defaulters-among-children-aged-12-23-months-in-ambo-town-oromia-ethiopia-a-case-control-study
#6
JOURNAL ARTICLE
Gurmessa Bekele, Jiregna Darega, Erimiyas Mulu, Menen Tsegaw
Immunization is a public health intervention to reduce morbidity and mortality among children. However, vaccination becomes more effective if the child can receive the full course of recommended vaccination doses according to the schedule. Many children fail to complete the full course of vaccination. To identify the determinants of immunization defaulters among children aged 12-23 months in Ambo town, Oromia, Ethiopia. A community-based, unmatched, case-control study was done from October 1 to 25, 2021...
December 31, 2024: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/38602539/immunogenicity-and-safety-of-concomitant-administration-of-recombinant-covid-19-vaccine-and-quadrivalent-inactivated-influenza-vaccine-in-chinese-adults-an-open-label-randomized-controlled-trial
#7
JOURNAL ARTICLE
Tao Huang, Jun Yu, Siyuan Zhang, Dewei Teng, Defang Dai, Yinbiao Zhu, Lidong Gao
The immunogenicity and safety of the concomitant administration of recombinant COVID-19 vaccine and quadrivalent inactivated influenza vaccine (Split Virion) (QIIV) in Chinese adults are unclear. In this open-label, randomized controlled trial, participants aged ≥ 18 years were recruited. Eligible healthy adults were randomly assigned (1:1) to receive QIIV at the same time as the first dose of COVID-19 vaccine (simultaneous-group) or 14 days after the second dose of COVID-19 vaccine (non-simultaneous-group)...
December 31, 2024: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/38602074/a-systematic-review-on-malaria-and-dengue-vaccines-for-the-effective-management-of-these-mosquito-borne-diseases-improving-public-health
#8
REVIEW
Hind M Al-Osaimi, Mohammed Kanan, Lujain Marghlani, Badria Al-Rowaili, Reem Albalawi, Abrar Saad, Saba Alasmari, Khaled Althobaiti, Zainab Alhulaili, Abeer Alanzi, Rawan Alqarni, Razan Alsofiyani, Reem Shrwani
Insect vector-borne diseases (VBDs) pose significant global health challenges, particularly in tropical and subtropical regions. The WHO has launched the "Global Vector Control Response (GVCR) 2017-2030" to address these diseases, emphasizing a comprehensive approach to vector control. This systematic review investigates the potential of malaria and dengue vaccines in controlling mosquito-borne VBDs, aiming to alleviate disease burdens and enhance public health. Following PRISMA 2020 guidelines, the review incorporated 39 new studies out of 934 identified records...
December 31, 2024: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/38599768/a-real-world-study-on-the-changing-characteristics-of-measles-antibodies-in-premature-infants-in-china
#9
JOURNAL ARTICLE
Mingyan Li, Weiwei Zhang, Shuangshuang Zheng, Junxia Guo, Hanqing He, Yongjun Ma, Yan Huang, Yan Feng, Chai Ji
The waning of maternal antibodies may cause infants to lose protection against measles before receiving measles-containing vaccine (MCV). The aim of this study is to investigate the changing characteristics and influencing factors of measles antibodies in preterm infants (PT), and to provide scientific basis for optimizing MCV vaccination strategy of the target population. Blood samples were collected from PT and full-term infants (FT) at the chronological age (CA) of 3, 6, and 12 months. Measles antibodies were quantitatively detected by enzyme-linked immunosorbent assay...
December 31, 2024: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/38599678/perceptions-of-dengue-risk-and-acceptability-of-a-dengue-vaccine-in-residents-of-puerto-rico
#10
JOURNAL ARTICLE
Coral Rosado-Santiago, Carmen L Pérez-Guerra, Nicole M Vélez-Agosto, Claudia Colón-Burgos, Karla M Marrero-Santos, Susanna K Partridge, Amy E Lockwood, Cathy Young, Steve H Waterman, Gabriela Paz-Bailey, Iris Cardona-Gerena, Angel Rivera, Laura E Adams, Joshua M Wong
Dengvaxia is the first dengue vaccine recommended in the United States (U.S.). It is recommended for children aged 9-16 y with laboratory-confirmed previous dengue infection and living in areas where dengue is endemic. We conducted focus groups with parents and in-depth interviews with key informants (i.e. practicing pediatricians, physicians from immunization clinics, university researchers, and school officials) in Puerto Rico (P.R.) to examine acceptability, barriers, and motivators to vaccinate with Dengvaxia...
December 31, 2024: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/38593326/human-vaccines-and-immunotherapeutics-news-march-2024
#11
EDITORIAL
Ronald Ellis, Adam Weiss
No abstract text is available yet for this article.
December 31, 2024: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/38593300/immunogenicity-of-covid-19-vaccines-in-patients-with-cirrhosis-expected-advantage-for-additional-dose-of-vaccine
#12
JOURNAL ARTICLE
Hinpetch Daungsupawong, Viroj Wiwanitkit
No abstract text is available yet for this article.
December 31, 2024: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/38584121/a-case-of-congenital-rubella-syndrome-and-epidemiology-of-related-cases-in-china-2014-2023
#13
JOURNAL ARTICLE
Xiaoying Gong, Canjie Zheng, Quanjun Fang, Wenjie Xu, Zhiying Yin
Rubella is a major cause of congenital defects, and the presence of rubella infection in a pregnant woman may lead to fetal death or congenital defects known as congenital rubella syndrome(CRS). Since China has not yet established a national CRS surveillance system, the true incidence cannot be determined. To understand the disease burden and epidemiological characteristics of CRS cases in China, the article reports the first case of CRS in Quzhou, China, and conducts a retrospective analysis of related cases that have been reported in China over the past decade...
December 31, 2024: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/38584120/misinformation-and-covid-19-vaccine-uptake-hesitancy-among-frontline-workers-in-tanzania-do-demographic-variables-matter
#14
JOURNAL ARTICLE
Juma James Masele
Although COVID-19 vaccination has been widely considered as an important remedy to confront COVID-19, people remain hesitant to take it. The objective of this study was to assess the moderation effects of demographic characteristics on the relationship between forms of misinformation and COVID-19 vaccine uptake hesitancy among frontline workers in Dar es Salaam and Dodoma, Tanzania. Using a sample of 200 respondents, it assessed the differences in ratings on misinformation regarding COVID-19 vaccine based on respondents' demographics...
December 31, 2024: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/38584118/comparison-of-t-cells-mediated-immunity-and-side-effects-of-mrna-vaccine-and-conventional-covid-19-vaccines-administrated-in-jordan
#15
JOURNAL ARTICLE
Hatim M Jaber, Saja Ebdah, Sameer A Al Haj Mahmoud, Luay Abu-Qatouseh, Yazan H Jaber
Various COVID-19 vaccines can affect the immune system. Discrepancies have been noted in immune system characteristics, such as T-lymphocyte levels, between vaccinated and non-vaccinated individuals. This study investigates the variations in immune responses among the four administered COVID-19 vaccines, influencing factors, and clinical outcomes in Jordan. A total of 350 adults, who were at least two doses vaccinated, were interviewed and blood samples were collected for subsequent laboratory analyses. The study involved the quantification of T-cells specifically targeting anti-SARS CoV-2 using Flow cytometry analysis...
December 31, 2024: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/38575528/factors-associated-with-pregnant-women-s-willingness-to-receive-maternal-pertussis-vaccination-in-guizhou-province-china-an-exploratory-cross-sectional-study
#16
JOURNAL ARTICLE
Feng Jiang, Xingui Ye, Ying Wang, Ning Tang, Jun Feng, Yuanxue Gao, Meiling Bao
The rise in pertussis incidence among infants in Guizhou, China underscores the need for maternal acellular pertussis vaccine (aP) immunization, a key strategy in protecting infants from severe health consequences. However, the willingness of pregnant women in Guizhou to receive this vaccine is not well-understood. This study aimed to explore pregnant women's intentions toward maternal pertussis vaccination in Guizhou and identify the associated factors. A questionnaire based on the health belief model, was administered in an exploratory cross-sectional study from January to February 2022...
December 31, 2024: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/38575525/rotavirus-vaccine-dose-two-dropout-and-its-associated-factors-among-children-who-received-rotavirus-vaccine-dose-one-in-sub-saharan-african-countries-a-multilevel-analysis-of-the-recent-demographic-and-health-survey
#17
JOURNAL ARTICLE
Belayneh Shetie Workneh, Enyew Getaneh Mekonen, Alebachew Ferede Zegeye, Almaz Tefera Gonete, Tewodros Getaneh Alemu, Tadesse Tarik Tamir, Berhan Tekeba, Mulugeta Wassie, Alemneh Tadesse Kassie, Mohammed Seid Ali
Rotavirus is the most common cause of diarrhea in children worldwide. In 2016, rotavirus infection resulted in 258 173 300 episodes of diarrhea and 128 500 child deaths in the globe. The study aimed to assess the magnitude of Rotavirus vaccine dose-two dropout and associated factors among children who received rotavirus vaccine dose-one in sub-Saharan African countries. The appended and most recent demographic and health survey (DHS) dataset of 17 sub-Saharan African countries was used for data analysis. A total of 73,396 weighted samples were used...
December 31, 2024: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/38575524/opportunities-and-challenges-for-human-papillomavirus-vaccination-in-china
#18
REVIEW
Chao Zhao, Yun Zhao, Jingran Li, Mingzhu Li, Yujing Shi, Lihui Wei
Current estimates of the HPV infection rate in China vary by geographic region (9.6-23.6%), with two age peaks in prevalence in women ≤20-25 years of age and 50-60 years of age. HPV-16, 52 and 58 are the most commonly-detected HPV genotypes in the Chinese population. In China, five HPV vaccines are licensed and several others are undergoing clinical trials. Multiple RCTs have shown the efficacy and safety of the bvHPV (Cervarix), Escherichia coli -produced bvHPV (Cecolin), Pichia pastoris -produced bvHPV (Walrinvax), qvHPV (Gardasil) and 9vHPV (Gardasil-9) vaccines in Chinese populations, including two studies showing long-term efficacy (≥8 years) for the bvHPV and qvHPV vaccines...
December 31, 2024: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/38575149/effectiveness-and-durability-of-mrna-1273-ba-4-ba-5-bivalent-vaccine-mrna-1273-222-against-sars-cov-2-ba-4-ba-5-and-xbb-sublineages
#19
JOURNAL ARTICLE
Bradley K Ackerson, Katia J Bruxvoort, Lei Qian, Lina S Sy, Sijia Qiu, Julia E Tubert, Gina S Lee, Jennifer H Ku, Ana Florea, Yi Luo, Radha Bathala, Julie Stern, Soon K Choi, Harpreet S Takhar, Michael Aragones, Morgan A Marks, Evan J Anderson, Cindy Ke Zhou, Tianyu Sun, Carla A Talarico, Hung Fu Tseng
Emerging SARS-CoV-2 sublineages continue to cause serious COVID-19 disease, but most individuals have not received any COVID-19 vaccine for >1 year. Assessment of long-term effectiveness of bivalent COVID-19 vaccines against circulating sublineages is important to inform the potential need for vaccination with updated vaccines. In this test-negative study at Kaiser Permanente Southern California, sequencing-confirmed BA.4/BA.5- or XBB-related SARS-CoV-2-positive cases (September 1, 2022 to June 30, 2023), were matched 1:3 to SARS-CoV-2-negative controls...
December 31, 2024: Human Vaccines & Immunotherapeutics
https://read.qxmd.com/read/38573783/parents-and-teachers-perspectives-on-a-school-located-influenza-vaccination-program-a-pilot-study-in-the-region-of-murcia-spain
#20
JOURNAL ARTICLE
Matilde Zornoza Moreno, Jaime Pérez-Martín, Marta Robles Mañueco
During the 2022-2023 season, the Region of Murcia (an autonomous community of Spain) introduced the influenza vaccination campaign in children aged 24-59 months with the live-attenuated influenza nasal spray vaccine. To expand coverage, a pilot study was conducted to include the 3- to 4-year population in 24 public schools. The aim of the study was to assess the experiences of parents and teachers involved in the project. This was a psychosocial qualitative study in which information was collected from a cohort of 23 parents and 17 teachers who attended three and two focus group sessions, respectively...
December 31, 2024: Human Vaccines & Immunotherapeutics
journal
journal
43830
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.