Read by QxMD icon Read

Brain and Behavior

Joel S Svensson, Emma Westerlind, Hanna C Persson, Katharina S Sunnerhagen
OBJECTIVES: To investigate the incidence and number of occupational gaps 5 years after stroke and find possible predictors and explanatory factors for increased number of experienced gaps. MATERIAL AND METHODS: The participants were diagnosed with first-time stroke in Gothenburg during 2009-2010. Medical records from their hospital stay were used to obtain baseline data. The Occupational Gaps Questionnaire and the Swedish stroke registers follow-up questionnaire were sent out...
February 19, 2019: Brain and Behavior
Arend M Hamming, Marianne A A van Walderveen, Inge A Mulder, Irene C van der Schaaf, L Jaap Kappelle, Birgitta K Velthuis, Michel D Ferrari, Gisela M Terwindt, Marieke C Visser, Wouter Schonewille, Ale Algra, Marieke J H Wermer
OBJECTIVES: Migraine is a risk factor for stroke, which might be explained by a higher prevalence in anatomical variants in the circle of Willis (CoW). Here, we compared the presence of CoW variants in patients with stroke with and without migraine. MATERIALS AND METHODS: Participants were recruited from the prospective Dutch acute Stroke Study. All participants underwent CT angiography on admission. Lifetime migraine history was assessed with a screening questionnaire and confirmed by an interview based on International Classification of Headache Disorders criteria...
February 16, 2019: Brain and Behavior
Luca Baldelli, Olga Addimanda, Marco Burattini, Giacomo Chiaro, Veronica Brusi, Elettra Pignotti, Riccardo Meliconi, Federica Provini
OBJECTIVES: To investigate the prevalence of REM sleep behavior disorder (RBD) in patients with inflammatory arthritis (IA) to ascertain if RBD could be an internal red flag signaling a fluctuating state of inflammation based on the theory of "protoconsciousness". MATERIALS & METHODS: One hundred and three patients with a confirmed diagnosis of IA were consecutively recruited. The patients underwent general (IA activity, functional status, laboratory tests) and neurological evaluations...
February 15, 2019: Brain and Behavior
Xuan Zhang, Zhiyi Song, Jingyi Ye, Ying Fu, Jinying Wang, Lei Su, Xiaodong Zhu, Meiyun Zhang, Yan Cheng, Wei Wu, Rong Xue
OBJECTIVES: To compare the sleep characteristics and cognition between rapid eye movement sleep behavior disorder (RBD) patients and non-RBD (nRBD) healthy control subjects and to determine the correlation between sleep and cognition in RBD patients. METHODS: Polysomnography (PSG) was performed to confirm and exclude RBD. Fifteen iRBD patients, 12 PD with RBD patients, and 23 matched nRBD healthy control subjects were enrolled. Subjective sleep and neuropsychological evaluations were performed...
February 14, 2019: Brain and Behavior
Jin-Yong Joung, Jung-Hyo Cho, Yun-Hee Kim, Seung-Hoon Choi, Chang-Gue Son
INTRODUCTION: Experimental studies and clinical observations have shown that stress can damage hepatic tissue both directly and indirectly. Many studies have partially revealed the contributors of stress-induced liver injury; however, the whole process has not yet been uncovered. This review aims to summarize the mechanisms that have been proposed to be involved. METHODS: A literature search was conducted using PubMed ( in its entirety up to March 2018, and analyzed the animal-derived mechanistic studies on stress-induced liver injury...
February 13, 2019: Brain and Behavior
Xiaobin Xu, Shijun Fan, Yuanqiao Guo, Ruei Tan, Junyu Zhang, Wenhua Zhang, Bing-Xing Pan, Nobumasa Kato
INTRODUCTION: Bisphenol A (BPA) is an endocrine disruptor widely used to manufacture consumer goods. Although the thyroid hormone (TH) disrupting potential of BPA has been thought to be responsible for the neuropsychiatric deficits in the animals that experienced perinatal BPA exposure, the TH availability change at the level of specific brain structures has not been subject to systematic investigation. METHODS: In the present study the impacts of perinatal BPA exposure (0...
February 13, 2019: Brain and Behavior
Emily W Baker, Holly A Kinder, Franklin D West
INTRODUCTION: Neural stem cells (NSCs) have demonstrated multimodal therapeutic function for stroke, which is the leading cause of long-term disability and the second leading cause of death worldwide. In preclinical stroke models, NSCs have been shown to modulate inflammation, foster neuroplasticity and neural reorganization, promote angiogenesis, and act as a cellular replacement by differentiating into mature neural cell types. However, there are several key technical questions to address before NSC therapy can be applied to the clinical setting on a large scale...
February 12, 2019: Brain and Behavior
Guy A Orban, Stefania Ferri, Artem Platonov
INTRODUCTION: Although it has become widely accepted that the action observation network (AON) includes three levels (occipito-temporal, parietal and premotor), little is known concerning the specific role of these levels within perceptual tasks probing action observation. Recent single cell studies suggest that the parietal level carries the information required to discriminate between two-alternative observed actions, but do not exclude possible contributions from the other two levels...
February 11, 2019: Brain and Behavior
Esther Heckendorf, Marian J Bakermans-Kranenburg, Marinus H van Ijzendoorn, Rens Huffmeijer
INTRODUCTION: Functional MRI (fMRI) is commonly used to investigate the neural mechanisms underlying psychological processes and behavioral responses. However, to draw well-founded conclusions from fMRI studies, more research on the reliability of fMRI is needed. METHODS: We invited a sample of 41 female students to participate in two identical fMRI sessions, separated by 5 weeks on average. To investigate the potential effect of left-handedness on the stability of neural activity, we oversampled left-handed participants (N = 20)...
February 9, 2019: Brain and Behavior
Jonathon Lee Reay, Paul van Schaik, Christopher James Wilson
BACKGROUND AND PURPOSE: The traditional herbal supplements Panax ginseng and Ginkgo biloba are self-medicated by members of the general public and prescribed by healthcare professionals in some EU countries for numerous health complaints. Clinical evidence is mixed and mechanisms of action are not fully understood. There is clinical interest into the synergistic effects of combining both herbs. METHODS: We systematically review the literature investigating the effects of combination treatments on physiological and psychological outcomes in humans...
February 6, 2019: Brain and Behavior
Frank Jonker, Wouter Weeda, Kim Rauwerda, Erik Scherder
BACKGROUND: The assumption is that executive dysfunctions (EF), associated with frontal lobe injury, are responsible for behavioral disturbances. Some studies do not find a relationship between EF and behavior following frontal lobe lesions. Our main goal of this study was to use a novel statistical method, graph theory, to analyze this relationship in different brain injury groups; frontal lobe damage, non-frontal lobe damage, and controls. Within the frontal group, we expect to find a pattern of executive nodes that are highly interconnected...
February 6, 2019: Brain and Behavior
Nikolay A Kostenikov, Boris L Zhuikov, Valeriy M Chudakov, Yuriy R Iliuschenko, Sergey V Shatik, Vadim V Zaitsev, Dmitriy S Sysoev, Andrey A Stanzhevskiy
INTRODUCTION: The applicability of "Rubidium Chloride, 82 Rb from Generator" radiopharmaceutical for brain tumors (BT) diagnostics is demonstrated on the basis of the application experience of the radiopharmaceutical in neurooncology. EXPERIMENTAL: A total of 21 patients with various brain tumors and nonneoplastic abnormal brain masses were investigated. RESULTS AND DISCUSSIONS: The results of the imaging and differential diagnostics of malignant and benign tumors, nonneoplastic abnormal brain masses and lesions revealed the prevalence of high uptake of the radiopharmaceutical in the malignant tumors in comparison with benign glioma and arteriovenous malformations in which 82 Rb-chloride accumulates in the vascular phase but does not linger further...
February 6, 2019: Brain and Behavior
Peiyu Li, Junwu Zhang, Xin Li, Hongwei Gao
OBJECTIVES: We evaluated the protective effects of protein phosphatase 2A (PP2A)/tristetraprolin (TTP) against brain edema in a rat model of cerebral hemorrhage, bleeding in the brain that occurs in tissues and ventricles. TTP is a well-known mRNA-binding protein and essential regulatory molecule for gene expression. METHODS: Cerebral hemorrhage was induced in male albino rats divided into four homogeneous groups: normal control (I), control (II), PP2A siRNA (III), and scrambled siRNA (IV)...
February 6, 2019: Brain and Behavior
Wei Hu, Dezhi Liu, Qin Li, Li Wang, Qiqiang Tang, Guoping Wang
BACKGROUND AND AIMS: Vitamin D deficiency has been linked to a higher risk of ischemic stroke. We therefore explored the relationship between serum 25-hydroxyvitamin D [25(OH)D] levels and early neurological deterioration (END) after acute ischemic stroke in a hospital-based prospective study. METHODS: From June 2016 to June 2018, patients with ischemic stroke within 48 hr from symptom onset were consecutively recruited. Serum 25(OH)D levels were measured at admission...
February 6, 2019: Brain and Behavior
Kristina M Gicas, Alex Cheng, Iris Rawtaer, Taylor S Willi, William J Panenka, Donna J Lang, Geoff N Smith, Fidel Vila-Rodriguez, Olga Leonova, Chantelle J Giesbrecht, Andrea A Jones, Alasdair M Barr, Ric M Procyshyn, Tari Buchanan, G William MacEwan, Wayne Su, Alexandra T Vertinsky, Alexander Rauscher, Norm O'Rourke, Wendy Loken Thornton, Allen E Thornton, William G Honer
OBJECTIVE: We investigated white matter differences associated with distinct neurocognitive profiles derived from a large cohort of marginally housed persons with comorbid physical and mental illnesses. Our prior work identified three profile cluster groups: a high functioning group (Cluster 1), a low functioning group with relative strength in decision-making (Cluster 3), and an intermediary group with a relative decision-making weakness (Cluster 2). This study extends previous findings of cortical gray matter differences between these groups with evidence for putative neurodevelopmental abnormalities in the low cognitive functioning group (i...
February 6, 2019: Brain and Behavior
Valentina De Giorgis, Silvia Masnada, Costanza Varesio, Matteo A Chiappedi, Martina Zanaboni, Ludovica Pasca, Melissa Filippini, Joyce A Macasaet, Marialuisa Valente, Cinzia Ferraris, Anna Tagliabue, Pierangelo Veggiotti
INTRODUCTION: Glucose Transporter Type I Deficiency Syndrome (GLUT1DS) classical symptoms are seizures, involuntary movements, and cognitive impairment but so far the literature has not devoted much attention to the last. METHODS: In our retrospective study involving 25 patients with established GLUT1DS diagnosis, we describe the cognitive impairment of these patients in detail and their response to the ketogenic diet in terms of cognitive improvement. RESULTS: We outlined a specific cognitive profile where performance skills were more affected than verbal ones, with prominent deficiencies in visuospatial and visuomotor abilities...
February 4, 2019: Brain and Behavior
Liang Huo, Ziteng Teng, Hua Wang, Xueyan Liu
BACKGROUND: Pettigrew syndrome (PGS) is a rare X-linked mental retardation that caused by AP1S2 mutation. The pathogenesis of AP1S2 deficiency has remained elusive. The purpose of this study is to give a comprehensive overview of the phenotypic and genetic spectrum of AP1S2 mutations. METHODS: This study systematically analyzed clinical features and genetic information of a Chinese family with AP1S2 variation, and reviewed previously reported literatures with the same gene variation...
February 4, 2019: Brain and Behavior
Hongxia Wang, Yan Sun, Jiaojiao Lv, Siyu Bo
OBJECTIVES: Internet addiction (IA) has been associated with widespread brain alterations. Functional connectivity (FC) and network analysis results related to IA are inconsistent between studies, and how network hubs change is not known. The aim of this study was to evaluate functional and topological networks using an unbiased minimum spanning tree (MST) analysis on electroencephalography (EEG) data in IA and healthy control (HC) college students. METHODS: In this study, Young's internet addiction test was used as an IA severity measure...
January 31, 2019: Brain and Behavior
Long-Biao Cui, Min Cai, Xing-Rui Wang, Yuan-Qiang Zhu, Liu-Xian Wang, Yi-Bin Xi, Hua-Ning Wang, Xia Zhu, Hong Yin
INTRODUCTION: Treatment response at an early stage of schizophrenia is of considerable value with regard to future management of the disorder; however, there are currently no biomarkers that can inform physicians about the likelihood of response. OBJECTS: We aim to develop and validate regional brain activity derived from functional magnetic resonance imaging (fMRI) as a potential signature to predict early treatment response in schizophrenia. METHODS: Amplitude of low-frequency fluctuation (ALFF) was measured at the start of the first/single episode resulting in hospitalization...
January 30, 2019: Brain and Behavior
Richard Silberstein, David A Camfield, Geoffrey Nield, Con Stough
INTRODUCTION: Creativity is a complex construct that lies at the core of what has made human civilizations possible. One frequently used measure of creativity is the Abbreviated Torrance Test for Adults that yields an overall creativity score. In this study, we examine the relationship between the task-related differences in brain functional connectivity and the creativity score in a male and female group of participants. METHODS: Brain functional connectivity was estimated from the steady-state visual evoked potential (SSVEP) event-related partial coherence in a group of 27 females and 27 males while they performed a low-demand visual vigilance task and the A-X version of the Continuous Performance Task...
January 27, 2019: Brain and Behavior
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"