Linh T Nguyen, Charlotte S Lo, Michael Fyrsta, Jessica Nie, Jennifer Y Yam, Pei-Hua Yen, Michael X Le, Karen Hersey, Miran Kenk, Megan Crumbaker, Neil Fleshner, Girish Kulkarni, Robert Hamilton, Michael Jewett, Antonio Finelli, Andrew Evans, Joan Sweet, Pamela S Ohashi, Anthony M Joshua
BACKGROUND: The evaluation of tumour-infiltrating lymphocytes (TILs) in solid malignancies has yielded insights into immune regulation within the tumour microenvironment and has also led to the development and optimisation of adoptive T cell therapies. OBJECTIVES: This study examined the in vitro expansion of TILs from prostate adenocarcinoma, as a preliminary step to evaluate the potential of TILs for adoptive T cell therapy. Design, Setting, and Participants ...
2022: Prostate Cancer