Marco Rastrelli, Mauro Alaibac, Roberto Stramare, Vanna Chiarion Sileni, Maria Cristina Montesco, Antonella Vecchiato, Luca Giovanni Campana, Carlo Riccardo Rossi
This paper reviews the epidemiology, diagnosis, and treatment of M zero cutaneous melanoma including the most recent developments. This review also examined the main risk factors for melanoma. Tumor thickness measured according to Breslow, mitotic rate, ulceration, and growth phase has the greatest predictive value for survival and metastasis. Wide excision of the primary tumor is the only potentially curative treatment for primary melanoma. The sentinel node biopsy must be performed on all patients who have a primary melanoma with a Breslow thickness > 1 mm, or if the melanoma is from 0,75 mm to 1 mm thick but it is ulcerated and/or the mitotic index is ≥1...
2013: ISRN Dermatology