journal
Journals American Journal of Nuclear Me...

American Journal of Nuclear Medicine and Molecular Imaging

https://read.qxmd.com/read/38204606/malignant-melanoma-of-gastrointestinal-tract-on-18-f-fdg-pet-ct-three-case-reports
#21
Wenpeng Huang, Yongkang Qiu, Xiaoyan Xiao, Liming Li, Qi Yang, Jianbo Gao, Lei Kang
Primary malignant melanoma most frequently occurs in the skin. Melanoma affecting the gastrointestinal (GI) tract has been substantiated for lesions occurring in the esophagus, stomach, small bowel, and anorectum through multiple published reports, given the presence of melanocytes in these areas. Nevertheless, owing to the exceedingly low incidence of this disease, reports on its clinical features are few, and treatment approaches lack standardization. In this study, we present three cases of GI melanoma with imaging manifestations, emphasizing the pivotal role of 18 F-FDG PET/CT in staging for GI melanoma...
2023: American Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/38204605/multimodality-imaging-of-an-unusual-giant-cell-tumor-of-thoracic-spine-with-mediastinal-invasion-a-case-report
#22
Wenpeng Huang, Yushuo Peng, Yongbai Zhang, Fangfang Chao, Liming Li, Yongkang Qiu, Jianbo Gao, Lei Kang
Giant cell tumor (GCT) is a benign yet locally aggressive bone neoplasm typically situated in the juxta-articular metaphysis of long bones. Although spinal involvement is rare, it is predominantly reported in the axial skeleton, with the sacrum being the primary location. Conversely, GCTs are notably uncommon in the thoracic spine. In this report, we present computed tomography (CT), magnetic resonance imaging (MRI), and 2-Deoxy-2-[fluorine-18]-fluoro-D-glucose (18 F-FDG) positron emission tomography combined with computed tomography (PET/CT) multimodality imaging findings of a 36-year-old woman diagnosed with a GCT of the thoracic spine...
2023: American Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/38204604/diagnosis-and-prognostic-predictive-value-of-delineation-methods-from-18-f-fdg-pet-ct-and-pet-mr-in-pancreatic-lesion
#23
JOURNAL ARTICLE
Fan Hu, Xiao Zhang, Hua Shu, Xiaoli Wang, Shuqian Feng, Mengmeng Hu, Xiaoli Lan, Chunxia Qin
The aim was to utilize three segmentation methods on 18 F-FDG PET/CT and PET/MR images of pancreatic neoplasm patients, and further compare the effectiveness in differentiating benign from malignant, TNM-stage and prognosis. We conducted a retrospective analysis of 51 patients with pancreatic neoplasm who had undergone 18 F-FDG PET/CT and PET/MR before treatment. The patients were categorized into malignant and benign groups. For each patient, the lesion was segmented by 3 thresholds and we recorded TNM-stage, treatment strategy, time to death, and the performance status of survivors...
2023: American Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/38204603/-18-f-fdg-pet-ct-in-extranodal-natural-killer-t-cell-lymphoma-a-comprehensive-evaluation-method
#24
REVIEW
Xiaoyue Zhang, Wenpeng Huang, Yongkang Qiu, Zhao Chen, Lele Song, Qi Yang, Lei Kang
Extranodal NK/T-cell lymphoma (ENKTL) is an uncommon subtype of non-Hodgkin's lymphoma that is closely related to Epstein-Barr virus (EBV) infection. ENKTL exhibits distinctive clinicopathological features among lymphomas and has poor overall survival in the absence of effective treatment. The timely and accurate diagnosis of ENKTL is crucial for effective treatment and a positive prognosis. 18 F-Fluorodeoxyglucose-positron emission tomography/computed tomography (18 F-FDG PET/CT) has emerged as an invaluable diagnostic modality for staging, curative effect evaluation, and prognosis analysis in ENKTL...
2023: American Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/38023820/incidence-of-99tc-mdp-uptake-in-the-external-occipital-protuberance-in-the-pediatric-population-the-new-normal
#25
JOURNAL ARTICLE
Razi Muzaffar, Amer Alassi, Mohamed Mashal, Medhat M Osman
BACKGROUND: Children and young adults have a vast array of electronics at their fingertips. While it can provide endless hours of entertainment and education, we are also seeing a structural consequence. Children are using these devices with their head tilted down with poor posture resulting in increased stress on the skull from attached structures which can lead to a bone spur (exostosis) at the external occipital protuberance (EOP). While typically painless, it can progress to necessitate surgical intervention...
2023: American Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/38023819/the-performance-and-applied-value-of-18-f-fdg-pet-ct-imaging-in-waldenstrom-macroglobulinemia
#26
JOURNAL ARTICLE
Bo Pan, Xingxing Zhu, Qiang Xie
Waldenstrom macroglobulinemia (WM) is a rare inert B lymphocyte lymphoma and the role of FDG PET/CT imaging in WM has not been well established. This study aimed to evaluate the metabolic status of WM by 18 F-FDG PET/CT imaging. We retrospectively analyzed 20 patients who underwent pretherapy 18 F-FDG PET-CT scan. All patients were diagnosed by bone marrow aspiration, laboratory examination and clinical symptoms. Bone marrow involvement was identified with 18 F-FDG PET/CT imaging in 16 of 20, and the mean SUVmax of bone marrow was 4...
2023: American Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/38023818/prediction-of-egfr-mutation-status-in-lung-adenocarcinoma-based-on-18-f-fdg-pet-ct-radiomic-features
#27
JOURNAL ARTICLE
Jian-Ling Tan, Liang Xia, Su-Guang Sun, Hui Zeng, Di-Yu Lu, Xiao-Jie Cheng
The earlier identification of EGFR mutation status in lung adenocarcinoma patients is crucial for treatment decision-making. Radiomics, which involves high-throughput extraction of imaging features from medical images for quantitative analysis, can quantify tumor heterogeneity and assess tumor biology non-invasively. This field has gained attention from researchers in recent years. The aim of this study is to establish a model based on 18 F-FDG PET/CT radiomic features to predict the epidermal growth factor receptor (EGFR) mutation status of lung adenocarcinoma and evaluate its performance...
2023: American Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/38023817/visualization-of-ferroptosis-in-brain-diseases-and-ferroptosis-inducing-nanomedicine-for-glioma
#28
REVIEW
Chenyang Wang, Li Wen, Kun Wang, Ruolin Wu, Mengting Li, Yajing Zhang, Zairong Gao
A remarkable body of new data establishes that many degenerative brain diseases and some acute injury situations in the brain may be associated with ferroptosis. In recent years, ferroptosis has also attracted great interest in the cancer research community, partly because it is a unique mode of cell death distinct from other forms and thus has great therapeutic potential for brain cancer. Glioblastoma is a highly aggressive and fatal human cancer, accounting for 60% of all primary brain tumors. Despite the development of various pharmacological and surgical modalities, the survival rates of high-grade gliomas have remained poor over the past few decades...
2023: American Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/38023816/diagnostic-efficacy-of-c-x-c-motif-chemokine-receptor-4-directed-pet-ct-in-newly-diagnosed-head-and-neck-squamous-cell-carcinoma-a-head-to-head-comparison-with-18-f-fdg
#29
JOURNAL ARTICLE
Yingjun Zhi, Rudolf A Werner, Andreas Schirbel, Takahiro Higuchi, Andreas K Buck, Aleksander Kosmala, Thorsten A Bley, Rudolf Hagen, Stephan Hackenberg, Andreas Rosenwald, Agmal Scherzad, Elena Gerhard-Hartmann, Sebastian E Serfling
BACKGROUND: The aim of this study was to determine the read-out capabilities of the novel C-X-C motif chemokine receptor 4 (CXCR4)-targeting radiotracer [68 Ga]Ga-PentixaFor compared to the reference radiotracer [18 F]FDG in untreated individuals with head and neck squamous cell carcinoma (HNSCC). MATERIAL AND METHODS: 12 patients with histologically confirmed HNSCC were scheduled for [18 F]FDG and [68 Ga]Ga-PentixaFor PET/CT. Maximum standardized uptake values (SUVmax ) and target-to-background ratios (TBR) were applied with vena cava superior serving as reference...
2023: American Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/38023815/marriage-of-radiotracers-and-total-body-pet-ct-rapid-imaging-system-current-status-and-clinical-advances
#30
REVIEW
Yuxuan Wu, Xiaona Sun, Boyang Zhang, Siqi Zhang, Xingkai Wang, Zhicheng Sun, Ruping Liu, Mingrong Zhang, Kuan Hu
Radiotracers and medical imaging equipment are the two main keys to molecular imaging. While radiotracers are of great interest to research and industry, medical imaging equipment technology is blossoming everywhere. Total-body PET/CT (TB-PET/CT) has emerged in response to this trend and is rapidly gaining traction in the fields of clinical oncology, cardiovascular medicine, inflammatory/infectious diseases, and pediatric diseases. In addition, the use of a growing number of radiopharmaceuticals in TB-PET/CT systems has shown promising results...
2023: American Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/37736496/automated-radiosynthesis-of-18-f-fmpep-d-2-for-cannabinoid-receptor-pet-imaging
#31
JOURNAL ARTICLE
Huailei Jiang, Yan Guo, Otto Muzik
The cannabinoid subtype 1 receptor (CB1R) is highly expressed in the central nervous system and abnormalities in regional CB1R density are associated with neurodegenerative disorders. The PET tracer [18 F]FMPEP- d 2 is an inverse CB1R agonist which was shown to be suitable for non-invasive PET imaging. In this work, we reported the fully automated radiosynthesis of [18 F]FMPEP- d 2 on a Synthra RNplus research module. In a total synthesis time of 70 min, [18 F]FMPEP- d 2 was obtained in 2.2 ± 0.1 GBq (n = 3) with excellent radiochemical and chemical purity...
2023: American Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/37736495/investigation-of-tumor-assessment-between-two-pet-systems-using-various-indices-comparison-between-pet-ct-and-pet-mri-systems
#32
JOURNAL ARTICLE
Hirotoshi Hotsumi, Shirou Ishii, Hiroki Suenaga, Shigeyasu Sugawara, Kenji Fukushima, Hiroshi Ito
This study aimed to determine the comparability of tumor-uptake indices of 18 F-FDG in positron emission tomography/computed tomography (PET/CT) and positron emission tomography/magnetic resonance imaging (PET/MRI). 2-[fluorine-18]-fluoro-2-deoxy-D-glucose (FDG) PET/CT and PET/MRI were performed on 55 patients with confirmed primary malignancies. PET/CT preceded PET/MRI in all examinations. Accumulation of 18 F-FDG in lesions and normal organs (brain, liver) was measured. Maximum and peak standardized uptake values (SUVs; SUVmax and SUVpeak , respectively), metabolic tumor volume (MTV), and total lesion glycolysis (TLG) with margin thresholds of SUV of 50% (MTV50% ; TLG50% , respectively) were measured as indices for comparison of measurements in tumors...
2023: American Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/37736494/duodenal-type-follicular-lymphoma-in-18-f-fdg-pet-ct-imaging-a-case-report
#33
Wenpeng Huang, Fangfang Chao, Yushuo Peng, Xiaoyue Zhang, Qi Yang, Lele Song, Liming Li, Lei Kang
Follicular lymphoma (FL) is a subtype of non-Hodgkin lymphoma (NHL) that is typically characterized by a slow-growing course. Duodenal-type follicular lymphoma (D-FL) was recently reclassified as a distinct variant. This subtype exhibits unique clinical and biological characteristics, which set it apart from other forms of FL. We report a case of a 36-year-old male patient with multiple, small, gray polypoid lesions in the descending duodenum which were detected by esophagogastroduodenoscopy. The pathological diagnosis was low-grade D-FL...
2023: American Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/37736493/evaluation-of-enhanced-permeability-effect-and-different-linear-energy-transfer-of-radionuclides-in-a-prostate-cancer-xenograft-model
#34
JOURNAL ARTICLE
Oskar Vilhelmsson Timmermand, Marcella Safi, Bo Holmqvist, Joanna Strand
We have previously investigated the biodistribution and therapy effect of a humanized monoclonal antibody targeting free prostate-specific antigen (fPSA) intended for theranostics of hormone-refractory prostate cancer. In the present study, we evaluated the off-target effect and different linear energy transfer (LET) radionuclides without the effect of PSA targeting by using an antibody with the same scaffold as previously used immunoconjugates but with random, non-specific, antigen binding region. This allows us to identify alterations generated by specific targeting and those related to passive bystander effects, such as enhanced permeability and retention (EPR)...
2023: American Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/37736492/the-role-of-18f-fluorodeoxyglucose-pet-computed-tomography-in-the-diagnosis-and-monitoring-of-large-vessel-vasculitides-a-review-article
#35
REVIEW
Mahshid Bahrami, Hossein Mohammadi, Hannaneh Mirgaloyebayat, Zahra Mohajeri, Pooya Fazeli, Azad Mojahedi, Ali Afsharirad, Reza Tavakoli, Amirhossein Sadeghian, Sayed Mohammad Amin Nourian
In the last two decades, advancements in positron emission tomography (PET) technology have increased the diagnostic accuracy of patients with large-vessel vasculitis (LVV). Numerous systematic reviews and meta-analyses have been conducted, and patients suspected of having LVV can be diagnosed earlier with 18F-FDG PET. Two subtypes, giant cell arteritis (GCA) and Takayasu arteritis (TA), will progress when their response to corticosteroids and enhanced immunosuppression is inadequate. In the majority of patients, disease activity cannot be monitored solely through laboratory procedures; consequently, glucose metabolism may be a source of potential biomarkers...
2023: American Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/37736491/novel-technique-of-detecting-inflammatory-and-osseous-changes-in-the-glenohumeral-joint-associated-with-patient-age-and-weight-using-fdg-and-naf-pet-imaging
#36
JOURNAL ARTICLE
Peter Sang Uk Park, Lori Jia, William Y Raynor, Om H Gandhi, Mia Mijung Park, Thomas J Werner, Poul Flemming Høilund-Carlsen, Abass Alavi
OBJECTIVE: The glenohumeral (GH) joint is a classic ball-and-socket joint of the shoulder subject to various pathologies including osteoarthritis (OA). Degenerative changes of the OA evident on traditional imaging are proceeded by molecular changes, which if detected early could enhance disease prevention and treatment. In this study, we use 18 F-FluoroDeoxyGlucose (FDG) and 18 F-sodium-fluoride (NaF)-PET/CT to investigate the effects limb laterality, age, and BMI on the inflammation and bone turnover of the GH shoulder joint...
2023: American Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/37457328/co-injection-of-anti-her2-antibody-trastuzumab-does-not-increase-efficacy-of-177-lu-lu-psma-617-therapy-in-an-animal-model-of-prostate-cancer
#37
JOURNAL ARTICLE
Ayman Abouzayed, Wahed Zedan, Mohamed Altai, Joanna Strand, Anders Örbom
One novel option for treating metastatic castration resistant prostate cancer is radionuclide therapy targeting prostate-specific membrane antigen (PSMA), e.g. [177 Lu]Lu-PSMA-617. Overexpression of HER2 has been found in 80% of metastatic cases of prostate cancer. Previous research showed that HER2 is elevated post irradiation in PC-3 prostate cancer cells. Co-treating with anti-HER2 antibody Trastuzumab gave less proliferation of irradiated tumor cells in vitro, and when using radionuclide therapy, also in vivo...
2023: American Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/37457327/erratum-single-center-developing-country-analysis-of-radium-223-therapy-in-prostate-cancer-preliminary-results
#38
Thaís B Minekawa, Allan O Santos, André G Moraes, André Sasse, Cleide A Silva, Marcelo T Lima, Mariana Camacho, Mariana C Lima, Elba Etchebehere
[This corrects the article on p. 352 in vol. 11, PMID: 34754606.].
2023: American Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/37457326/multimodality-imaging-of-spleen-involvement-in-erdheim-chester-disease-mimicking-splenic-hemangioma-a-unique-case-report
#39
Wenpeng Huang, Yongkang Qiu, Zhao Chen, Qi Yang, Lin Nong, Lei Kang
Erdheim-Chester disease (ECD) is a rare and clinically heterogeneous non-Langerhans cell histiocytosis, and its diagnosis relies on established clinical, radiologic, histopathological criteria. ECD can be evaluated by whole-body preoperative imaging methods. Although 18 F-FDG PET/CT shows negative findings in some splenic benign or borderline lesions, such as splenic inflammatory myofibroblastic tumors and hemangioendotheliomas, it can provide value in differentiating some malignant diseases, such as hemangiosarcoma and metastases...
2023: American Journal of Nuclear Medicine and Molecular Imaging
https://read.qxmd.com/read/37457325/mri-findings-in-movement-disorders-and-associated-sleep-disturbances
#40
REVIEW
Sadegh Ghaderi, Asra Karami, Azadeh Ghalyanchi-Langeroudi, Negar Abdi, Seyedeh Shadi Sharif Jalali, Masoud Rezaei, Parastou Kordestani-Moghadam, Shabnam Banisharif, Maryam Jalali, Sana Mohammadi, Mahdi Mohammadi
BACKGROUND: One of the most useful tools for identifying sleep disturbances is neuroimaging, especially magnetic resonance imaging (MRI). This review research was to look at the role of MRI findings in movement disorders and sleep disturbances. METHODS: This review collects all MRI data on movement disorders and sleep disruptions. Between 2000 and 2022, PubMed and Google Scholar were utilized to find original English publications and reviews. According to the inclusion and exclusion criteria, around 100 publications were included...
2023: American Journal of Nuclear Medicine and Molecular Imaging
journal
journal
43650
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.