Ioannis D Xynos, Nicolaos Kavantzas, Smaro Tsaousi, Michalis Zacharakis, George Agrogiannis, Christos Kosmas, Andreas Lazaris, John Sarantonis, Stavros Sougioultzis, Dimitrios Tzivras, Aris Polyzos, Efstratios S Patsouris, Nikolas Tsavaris
Objective. To evaluate the prognostic significance of microscopically assessed DNA ploidy and other clinical and laboratory parameters in stage IV colorectal cancer (CRC). Methods. 541 patients with histologically proven stage IV CRC treated with palliative chemotherapy at our institution were included in this retrospective analysis, and 9 variables (gender, age, performance status, carcinoembryonic antigen, cancer antigen 19-9, C-Reactive Protein (CRP), anaemia, hypoalbuminaemia, and ploidy (DNA Index)) were assessed for their potential relationship to survival...
2013: ISRN Gastroenterology