journal
https://read.qxmd.com/read/38597975/oxygenation-management-during-veno-arterial-ecmo-support-for-cardiogenic-shock-a-multicentric-retrospective-cohort-study
#1
JOURNAL ARTICLE
Hadrien Winiszewski, Thibault Vieille, Pierre-Grégoire Guinot, Nicolas Nesseler, Mael Le Berre, Laure Crognier, Anne-Claude Roche, Jean-Luc Fellahi, Nicolas D'Ostrevy, Zied Ltaief, Juliette Didier, Osama Abou Arab, Simon Meslin, Vincent Scherrer, Guillaume Besch, Alexandra Monnier, Gael Piton, Antoine Kimmoun, Gilles Capellier
BACKGOUND: Hyperoxemia is common and associated with poor outcome during veno-arterial extracorporeal membrane oxygenation (VA ECMO) support for cardiogenic shock. However, little is known about practical daily management of oxygenation. Then, we aim to describe sweep gas oxygen fraction (FS O2 ), postoxygenator oxygen partial pressure (PPOST O2 ), inspired oxygen fraction (FI O2 ), and right radial arterial oxygen partial pressure (Pa O2 ) between day 1 and day 7 of peripheral VA ECMO support...
April 10, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38594419/factors-associated-with-adverse-outcome-among-children-with-sickle-cell-disease-admitted-to-the-pediatric-intensive-care-unit-an-observational-cohort
#2
JOURNAL ARTICLE
Michaël Levy, Jérôme Naudin, Guillaume Geslain, Arielle Maroni, Bérengère Koehl, Fleur Le Bourgeois, Géraldine Poncelet, Maryline Chomton, Anna Deho, Sébastien Julliand, Stéphane Dauger, Julie Sommet
BACKGROUND: Sickle cell disease (SCD) is one of the most frequent inherited diseases in the world. Over the last decades, in high-income countries, an important decrease in mortality have been observed due to the improvement of care. However, children with SCD can become critically ill and require admission in Pediatric Intensive Care Units (PICU). The purpose of this study was to describe the epidemiology of children with SCD admitted to PICU for acute crisis and to identify factors associated with adverse outcome (AO)...
April 10, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38592568/effect-of-volume-infusion-on-left-atrial-strain-in-acute-circulatory-failure
#3
JOURNAL ARTICLE
Marta Cicetti, François Bagate, Cristina Lapenta, Ségolène Gendreau, Paul Masi, Armand Mekontso Dessap
BACKGROUND: Left atrial strain (LAS) is a measure of atrial wall deformation during cardiac cycle and reflects atrial contribution to cardiovascular performance. Pathophysiological significance of LAS in critically ill patients with hemodynamic instability has never been explored. This study aimed at describing LAS and its variation during volume expansion and to assess the relationship between LAS components and fluid responsiveness. METHODS: This prospective observational study was performed in a French ICU and included patients with acute circulatory failure, for whom the treating physician decided to proceed to volume expansion (rapid infusion of 500 mL of crystalloid solution)...
April 9, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38592412/association-of-socioeconomic-deprivation-with-outcomes-in-critically-ill-adult-patients-an-observational-prospective-multicenter-cohort-study
#4
JOURNAL ARTICLE
Morgan Benaïs, Matthieu Duprey, Laura Federici, Michel Arnaout, Pierre Mora, Marc Amouretti, Irma Bourgeon-Ghittori, Stéphane Gaudry, Pierre Garçon, Danielle Reuter, Guillaume Geri, Bruno Megarbane, Jordane Lebut, Armand Mekontso-Dessap, Jean-Damien Ricard, Daniel da Silva, Etienne de Montmollin
BACKGROUND: The influence of socioeconomic deprivation on health inequalities is established, but its effect on critically ill patients remains unclear, due to inconsistent definitions in previous studies. METHODS: Prospective multicenter cohort study conducted from March to June 2018 in eight ICUs in the Greater Paris area. All admitted patients aged ≥ 18 years were enrolled. Socioeconomic phenotypes were identified using hierarchical clustering, based on education, health insurance, income, and housing...
April 9, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38587575/influence-of-fluid-accumulation-on-major-adverse-kidney-events-in-critically-ill-patients-an-observational-cohort-study
#5
JOURNAL ARTICLE
Debora M Hofer, Livio Ruzzante, Jan Waskowski, Anna S Messmer, Carmen A Pfortmueller
BACKGROUND: Fluid accumulation (FA) is known to be associated with acute kidney injury (AKI) during intensive care unit (ICU) stay but data on mid-term renal outcome is scarce. The aim of this study was to investigate the association between FA at ICU day 3 and major adverse kidney events in the first 30 days after ICU admission (MAKE30). METHODS: Retrospective, single-center cohort study including adult ICU patients with sufficient data to compute FA and MAKE30...
April 8, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38565811/severe-legionnaires-disease
#6
REVIEW
Jordi Rello, Camille Allam, Alfonsina Ruiz-Spinelli, Sophie Jarraud
BACKGROUND: Legionnaires' disease (LD) is a common but under-diagnosed cause of community-acquired pneumonia (CAP), although rapid detection of urine antigen testing (UAT) and advances in molecular testing have improved the diagnosis. LD entails intensive care unit (ICU) admission in almost one-third of cases, and the mortality rate ranges from 4% to 40%. This review aims to discuss recent advances in the study of this condition and to provide an update on the diagnosis, pathogenesis and management of severe LD...
April 2, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38563888/positive-end-expiratory-pressure-and-left-ventricular-function-are-key-factors-affecting-right-ventricular-to-pulmonary-arterial-coupling
#7
LETTER
Cristina Santonocito, Siddharth Dugar, Filippo Sanfilippo
No abstract text is available yet for this article.
April 2, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38558273/should-initial-icu-admission-become-a-standard-of-care-for-acute-bacterial-meningitis
#8
EDITORIAL
Michael Thy, Claire Dupuis, Jean-François Timsit, Romain Sonneville
No abstract text is available yet for this article.
April 1, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38558268/capillary-refill-time-response-to-a-fluid-challenge-or-a-vasopressor-test-an-observational-proof-of-concept-study
#9
JOURNAL ARTICLE
Glenn Hernández, Emilio Daniel Valenzuela, Eduardo Kattan, Ricardo Castro, Camila Guzmán, Alicia Elzo Kraemer, Nicolás Sarzosa, Leyla Alegría, Roberto Contreras, Vanessa Oviedo, Sebastián Bravo, Dagoberto Soto, Claudia Sáez, Hafid Ait-Oufella, Gustavo Ospina-Tascón, Jan Bakker
BACKGROUND: Several studies have validated capillary refill time (CRT) as a marker of tissue hypoperfusion, and recent guidelines recommend CRT monitoring during septic shock resuscitation. Therefore, it is relevant to further explore its kinetics of response to short-term hemodynamic interventions with fluids or vasopressors. A couple of previous studies explored the impact of a fluid bolus on CRT, but little is known about the impact of norepinephrine on CRT when aiming at a higher mean arterial pressure (MAP) target in septic shock...
April 1, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38557917/pressure-for-change-can-we-continue-to-ignore-the-lack-of-evidence-for-blood-pressure-augmentation-to-treat-delayed-neurological-deficit-following-subarachnoid-haemorrhage
#10
EDITORIAL
Ronan O'Leary, Jonathan P Coles, Lara Prisco
No abstract text is available yet for this article.
April 1, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38555336/the-association-of-premorbid-conditions-with-6-month-mortality-in-acutely-admitted-icu-patients-over-80%C3%A2-years
#11
JOURNAL ARTICLE
Dylan W de Lange, Ivo W Soliman, Susannah Leaver, Ariane Boumendil, Lenneke E M Haas, Ximena Watson, Carol Boulanger, Wojciech Szczeklik, Antonio Artigas, Alessandro Morandi, Finn Andersen, Christian Jung, Rui Moreno, Sten Walther, Sandra Oeyen, Joerg C Schefold, Maurizio Cecconi, Brian Marsh, Michael Joannidis, Yuriy Nalapko, Muhammed Elhadi, Jesper Fjølner, Bertrand Guidet, Hans Flaatten
BACKGROUND: Premorbid conditions influence the outcome of acutely ill adult patients aged 80 years and over who are admitted to the ICU. The aim of this study was to determine the influence of such premorbid conditions on 6 month survival. METHODS: Prospective cohort study in 242 ICUs from 22 countries including patients 80 years or above, admitted over a 6 months period to an ICU between May 2018 and May 2019. Only emergency (acute) ICU admissions in adult patients ≥ 80 years of age were eligible...
March 30, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38553663/management-of-cardiogenic-shock-a-narrative-review
#12
REVIEW
Driss Laghlam, Sarah Benghanem, Sofia Ortuno, Nadia Bouabdallaoui, Stephane Manzo-Silberman, Olfa Hamzaoui, Nadia Aissaoui
Cardiogenic shock (CS) is characterized by low cardiac output and sustained tissue hypoperfusion that may result in end-organ dysfunction and death. CS is associated with high short-term mortality, and its management remains challenging despite recent advances in therapeutic options. Timely diagnosis and multidisciplinary team-based management have demonstrated favourable effects on outcomes. We aimed to review evidence-based practices for managing patients with ischemic and non-ischemic CS, detailing the multi-organ supports needed in this critically ill patient population...
March 30, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38548917/clinical-description-and-outcome-of-overall-varicella-zoster-virus-related-organ-dysfunctions-admitted-in-intensive-care-units-the-vazorea-cohort-study
#13
JOURNAL ARTICLE
Jolan Malherbe, Pierre Godard, Jean-Claude Lacherade, Valentin Coirier, Laurent Argaud, Hervé Hyvernat, Francis Schneider, Julien Charpentier, Florent Wallet, Juliette Pocquet, Gaëtan Plantefeve, Jean-Pierre Quenot, Pierre Bay, Agathe Delbove, Hugues Georges, Tomas Urbina, David Schnell, Charlène Le Moal, Matthieu Stanowski, Corentin Muris, Maud Jonas, Bertrand Sauneuf, Olivier Lesieur, Amaury Lhermitte, Laure Calvet, Ines Gueguen, Damien du Cheyron
BACKGROUND: Due to aging population and increasing part of immunocompromised patients, a raise in life-threatening organ damage related to VZV can be expected. Two retrospective studies were already conducted on VZV in ICU but focused on specific organ injury. Patients with high-risk of VZV disease still must be identified. The objective of this study was to report the clinical features and outcome of all life-threatening VZV manifestations requiring intensive care unit (ICU) admission...
March 29, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38536623/gut-barrier-dysfunction-and-the-risk-of-icu-acquired-bacteremia-a-case-control-study
#14
JOURNAL ARTICLE
Meri R J Varkila, Diana M Verboom, Lennie P G Derde, Tom van der Poll, Marc J M Bonten, Olaf L Cremer
BACKGROUND: Impaired intestinal barrier function can enable passage of enteric microorganisms into the bloodstream and lead to nosocomial bloodstream infections during critical illness. We aimed to determine the relative importance of gut translocation as a source for ICU-acquired enterococcal bacteremia of unknown origin. METHODS: We conducted a nested case-control study in two mixed medical-surgical tertiary ICUs in the Netherlands among patients enrolled between 2011 and 2018...
March 27, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38536545/early-sevoflurane-sedation-in-severe-covid-19-related-lung-injury-patients-a-pilot-randomized-controlled-trial
#15
JOURNAL ARTICLE
Beatrice Beck-Schimmer, Erik Schadde, Urs Pietsch, Miodrag Filipovic, Seraina Dübendorfer-Dalbert, Patricia Fodor, Tobias Hübner, Reto Schuepbach, Peter Steiger, Sascha David, Bernard D Krüger, Thomas A Neff, Martin Schläpfer
BACKGROUND: This study aimed to assess a potential organ protective effect of volatile sedation in a scenario of severe inflammation with an early cytokine storm (in particular IL-6 elevation) in patients suffering from COVID-19-related lung injury with invasive mechanical ventilation and sedation. METHODS: This is a small-scale pilot multicenter randomized controlled trial from four tertiary hospitals in Switzerland, conducted between April 2020 and May 2021. 60 patients requiring mechanical ventilation due to severe COVID-19-related lung injury were included and randomized to 48-hour sedation with sevoflurane vs...
March 27, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38536534/serial-daily-lactate-levels-association-with-30-day-outcome-in-cardiogenic-shock-patients-treated-with-va-ecmo-a-post-hoc-analysis-of-the-hypo-ecmo-study
#16
JOURNAL ARTICLE
Bruno Levy, Nicolas Girerd, Guillaume Baudry, Kevin Duarte, Samuel Cuau, Jan Bakker, Antoine Kimmoun
BACKGROUND: Reliable predictors of outcomes in venoarterial extracorporeal membrane oxygenation (VA-ECMO) therapy are limited. While elevated lactate levels over time have been linked to outcomes in cardiogenic shock (CS), their significance in VA-ECMO-treated patients remains inconclusive. METHODS: We conducted a post hoc analysis of data from the HYPO-ECMO trial, which compared normothermia to moderate hypothermia in CS patients supported by VA-ECMO. We examined daily lactate levels collected over a week to assess their correlation with 30-day mortality...
March 27, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38532049/right-ventricular-injury-in-patients-with-covid-19-related-ards-eligible-for-ecmo-support-a-multicenter-retrospective-study
#17
JOURNAL ARTICLE
Matthieu Petit, Misylias Bouaoud, Edouard Jullien, Adrien Joseph, Bruno Evrard, Cyril Charron, Anousone Daulasim, Annick Legras, Maeva Gourraud, Marine Goudelin, Philippe Vignon, Antoine Vieillard-Baron
BACKGROUND: Coronavirus disease 2019 (COVID-19)-related acute respiratory distress syndrome (ARDS) is associated with high mortality. Extracorporeal membrane oxygenation (ECMO) has been proposed in this setting, but optimal criteria to select target patients remain unknown. Our hypothesis is that evaluation of right ventricular (RV) function could be helpful. The aims of our study were to report the incidence and outcomes of patients eligible for ECMO according to EOLIA criteria, and to identify a subgroup of patients with RV injury, which could be a target for ECMO...
March 26, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38530515/assessment-of-covid-19-related-right-ventricular-morphological-and-functional-alterations-and-evaluation-of-their-impact-on-the-course-of-the-disease
#18
LETTER
Michael Dandel
No abstract text is available yet for this article.
March 26, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38457010/diaphragm-thickness-modifications-and-associated-factors-during-va-ecmo-for-a-cardiogenic-shock-a-cohort-study
#19
JOURNAL ARTICLE
Pierre-Henri Moury, Alexandre Béhouche, Sébastien Bailly, Zoé Durand, Géraldine Dessertaine, Angelina Pollet, Samir Jaber, Samuel Verges, Pierre Albaladejo
BACKGROUND: The incidence, causes and impact of diaphragm thickness evolution in veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for cardiogenic shock are unknown. Our study investigates its evolution during the first week of VA-ECMO and its relationship with sweep gas flow settings. METHODS: We conducted a prospective monocentric observational study in a 12-bed ICU in France, enrolling patients on the day of the VA-ECMO implantation. The diaphragm thickness and the diaphragm thickening fraction (as index of contractile activity, dTF; dTF < 20% defined a low contractile activity) were daily measured for one week using ultrasound...
March 8, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38448617/letter-on-bioimpedance-assessed-muscle-wasting-and-its-relation-to-nutritional-intake-during-the-first-week-of-icu-a-pre-planned-secondary-analysis-of-nutriti-study
#20
LETTER
Libing Jiang, Shanxiang Xu
No abstract text is available yet for this article.
March 7, 2024: Annals of Intensive Care
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