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Annals of Intensive Care

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https://read.qxmd.com/read/30758680/effects-of-chloride-content-of-intravenous-crystalloid-solutions-in-critically-ill-adult-patients-a-meta-analysis-with-trial-sequential-analysis-of-randomized-trials
#1
Ming Xue, Xiwen Zhang, Feng Liu, Wei Chang, Jianfeng Xie, Jingyuan Xu, Yi Yang, Haibo Qiu
BACKGROUND: Intravenous crystalloid solutions are administered commonly for critically ill patients. We performed this meta-analysis of randomized trials with trial sequential analysis (TSA) to evaluate effects of chloride content of intravenous crystalloid solutions on clinical outcomes among critically ill adult patients. METHODS: Electronic databases were searched up to June 1, 2018, for randomized trials of use of balanced crystalloids versus 0.9% saline solutions in critically ill adult patients...
February 13, 2019: Annals of Intensive Care
https://read.qxmd.com/read/30742240/the-association-of-intravenous-insulin-and-glucose-infusion-with-intensive-care-unit-and-hospital-mortality-a-retrospective-study
#2
Sigrid C van Steen, Saskia Rijkenberg, Peter H J van der Voort, J Hans DeVries
BACKGROUND: We assessed the association of intravenous insulin and glucose infusion with intensive care unit (ICU) and hospital mortality. METHODS: For this retrospective association study, we used data from all patients admitted to a medical-surgical ICU between January 2012 and September 2017. We excluded patients admitted < 24 h, patients with a diabetic ketoacidosis, patients with a therapy restriction upon ICU admission and readmissions. Using multivariate logistic regression, we examined the relation between intravenous insulin and glucose infusion and ICU and hospital mortality for all patients...
February 11, 2019: Annals of Intensive Care
https://read.qxmd.com/read/30737559/renal-protection-in-sepsis-is-hypertonic-sodium-lactate-the-solution
#3
EDITORIAL
Patrick M Honore, Leonel Barreto Gutierrez, Herbert D Spapen
No abstract text is available yet for this article.
February 8, 2019: Annals of Intensive Care
https://read.qxmd.com/read/30725235/the-clinical-efficacy-of-intravenous-igm-enriched-immunoglobulin-pentaglobin-in-sepsis-or-septic-shock-a-meta-analysis-with-trial-sequential-analysis
#4
Jie Cui, Xuxia Wei, Haijin Lv, Yuntao Li, Ping Li, Zhen Chen, Genglong Liu
BACKGROUND: Sepsis is characterized by a complex immune response. This meta-analysis evaluated the clinical effectiveness of intravenous IgM-enriched immunoglobulin (IVIgGM) in patients with sepsis and septic shock. METHODS: Four databases, PubMed, the Cochrane Library, the ISI Web of Knowledge, and Embase, were systematically searched from inception to June 2018 to update the 2013 edition of the Cochrane review by two investigators, who independently selected studies, extracted relevant data, and evaluated study quality...
February 6, 2019: Annals of Intensive Care
https://read.qxmd.com/read/30715638/risk-factors-for-mortality-in-elderly-and-very-elderly-critically-ill-patients-with-sepsis-a-prospective-observational-multicenter-cohort-study
#5
Ignacio Martin-Loeches, Maria Consuelo Guia, Maria Sole Vallecoccia, David Suarez, Mercedes Ibarz, Marian Irazabal, Ricard Ferrer, Antonio Artigas
BACKGROUND: Age has been traditionally considered a risk factor for mortality in elderly patients admitted to intensive care units. The aim of this prospective, observational, multicenter cohort study is to determine the risk factors for mortality in elderly and very elderly critically ill patients with sepsis. RESULTS: A total of 1490 patients with ≥ 65 years of age were included in the study; most of them 1231 (82.6%) had a cardiovascular failure. The mean age (± SD) was 74...
February 4, 2019: Annals of Intensive Care
https://read.qxmd.com/read/30707321/severe-toxicity-from-checkpoint-protein-inhibitors-what-intensive-care-physicians-need-to-know
#6
REVIEW
Virginie Lemiale, Anne-Pascale Meert, François Vincent, Michael Darmon, Philippe R Bauer, Andry Van de Louw, Elie Azoulay
Checkpoint protein inhibitor antibodies (CPI), including cytotoxic T-lymphocyte-associated antigen 4 inhibitors (ipilimumab, tremelimumab) and the programmed cell death protein 1 pathway/programmed cell death protein 1 ligand inhibitors (pembrolizumab, nivolumab, durvalumab, atezolizumab), have entered routine practice for the treatment of many cancers. They improve the outcome for many cancers, and more patients will be treated with CPI in the future. Although CPI can lead to adverse events (AE) less frequently than for chemotherapy, their use can require intensive care unit admission in case of severe immune-related adverse events (IrAE)...
February 1, 2019: Annals of Intensive Care
https://read.qxmd.com/read/30707314/impact-of-levosimendan-on-weaning-from-peripheral-venoarterial-extracorporeal-membrane-oxygenation-in-intensive-care-unit
#7
Shamir Vally, Cyril Ferdynus, Romain Persichini, Bruno Bouchet, Eric Braunberger, Hugo Lo Pinto, Olivier Martinet, David Vandroux, Thomas Aujoulat, Jérôme Allyn, Nicolas Allou
BACKGROUND: Few data are available on the impact of levosimendan in refractory cardiogenic shock patients undergoing peripheral venoarterial extracorporeal membrane oxygenation (VA-ECMO). The aim of this study was to evaluate the impact of levosimendan on VA-ECMO weaning in patients hospitalized in intensive care unit (ICU). METHODS: This retrospective cohort study was conducted in a French university hospital from 2010 to 2017. All patients hospitalized in ICU undergoing VA-ECMO were consecutively evaluated...
February 1, 2019: Annals of Intensive Care
https://read.qxmd.com/read/30706173/hemoadsorption-therapy-in-the-critically-ill-solid-base-but-clinical-haze
#8
EDITORIAL
Patrick M Honoré, David De Bels, Leonel Barreto Gutierrez, Herbert D Spapen
No abstract text is available yet for this article.
January 31, 2019: Annals of Intensive Care
https://read.qxmd.com/read/30706172/factors-associated-with-renal-doppler-resistive-index-in-critically-ill-patients-a-prospective-cohort-study
#9
Raphael A G Oliveira, Pedro V Mendes, Marcelo Park, Leandro U Taniguchi
BACKGROUND: The renal Doppler resistive index (renal RI) is a noninvasive tool that has been used to assess renal perfusion in the intensive care unit (ICU) setting. However, many parameters have been described as influential on the values of renal RI. Therefore, we proposed this study to evaluate the variables that could impact renal RI in critically ill patients. METHODS: A prospective observational study was performed in a 14-bed medical-surgical adult ICU. All consecutive patients admitted to the ICU during the study period were evaluated for eligibility...
January 31, 2019: Annals of Intensive Care
https://read.qxmd.com/read/30701448/current-use-of-vasopressors-in-septic-shock
#10
Thomas W L Scheeren, Jan Bakker, Daniel De Backer, Djillali Annane, Pierre Asfar, E Christiaan Boerma, Maurizio Cecconi, Arnaldo Dubin, Martin W Dünser, Jacques Duranteau, Anthony C Gordon, Olfa Hamzaoui, Glenn Hernández, Marc Leone, Bruno Levy, Claude Martin, Alexandre Mebazaa, Xavier Monnet, Andrea Morelli, Didier Payen, Rupert Pearse, Michael R Pinsky, Peter Radermacher, Daniel Reuter, Bernd Saugel, Yasser Sakr, Mervyn Singer, Pierre Squara, Antoine Vieillard-Baron, Philippe Vignon, Simon T Vistisen, Iwan C C van der Horst, Jean-Louis Vincent, Jean-Louis Teboul
BACKGROUND: Vasopressors are commonly applied to restore and maintain blood pressure in patients with sepsis. We aimed to evaluate the current practice and therapeutic goals regarding vasopressor use in septic shock as a basis for future studies and to provide some recommendations on their use. METHODS: From November 2016 to April 2017, an anonymous web-based survey on the use of vasoactive drugs was accessible to members of the European Society of Intensive Care Medicine (ESICM)...
January 30, 2019: Annals of Intensive Care
https://read.qxmd.com/read/30701392/the-prognostic-accuracy-evaluation-of-saps-3-sofa-and-apache-ii-scores-for-mortality-prediction-in-the-surgical-icu-an-external-validation-study-and-decision-making-analysis
#11
Antônio Luis Eiras Falcão, Alexandre Guimarães de Almeida Barros, Angela Alcântara Magnani Bezerra, Natália Lopes Ferreira, Claudinéia Muterle Logato, Filipa Pais Silva, Ana Beatriz Francioso Oliveira do Monte, Rodrigo Marques Tonella, Luciana Castilho de Figueiredo, Rui Moreno, Desanka Dragosavac, Nelson Adami Andreollo
BACKGROUND: The early postoperative period is critical for surgical patients. SOFA, SAPS 3 and APACHE II are prognostic scores widely used to predict mortality in ICU patients. This study aimed to evaluate these index tests for their prognostic accuracy for intra-ICU and in-hospital mortalities as target conditions in patients admitted to ICU after urgent or elective surgeries and to test whether they aid in decision-making. The process comprised the assessment of discrimination through analysis of the areas under the receiver operating characteristic curves and calibration of the prognostic models for the target conditions...
January 30, 2019: Annals of Intensive Care
https://read.qxmd.com/read/30701391/comparing-video-and-direct-laryngoscopy-for-tracheal-intubation-in-the-general-ward
#12
LETTER
Liu-Jia-Zi Shao, Fu-Shan Xue, Rui-Juan Guo, He Yang
No abstract text is available yet for this article.
January 30, 2019: Annals of Intensive Care
https://read.qxmd.com/read/30701381/acute-fibrinolysis-shutdown-occurs-early-in-septic-shock-and-is-associated-with-increased-morbidity-and-mortality-results-of-an-observational-pilot-study
#13
Felix Carl Fabian Schmitt, Vasil Manolov, Jakob Morgenstern, Thomas Fleming, Stefan Heitmeier, Florian Uhle, Mohammed Al-Saeedi, Thilo Hackert, Thomas Bruckner, Herbert Schöchl, Markus Alexander Weigand, Stefan Hofer, Thorsten Brenner
BACKGROUND: Septic coagulopathy represents a very dynamic disease entity, tilting from initial hypercoagulability towards a subsequent hypocoagulable disease state, entitled overt disseminated intravascular coagulation. Acute fibrinolysis shutdown has recently been described to be a crucial component of initial hypercoagulability in critically ill patients, although the underlying pathomechanisms, the specific temporal kinetics and its outcome relevance in patients with sepsis remain to be determined...
January 30, 2019: Annals of Intensive Care
https://read.qxmd.com/read/30684052/infectious-complications-following-heart-transplantation-in-the-era-of-high-priority-allocation-and-extracorporeal-membrane-oxygenation
#14
Stéphanie Pons, Romain Sonneville, Lila Bouadma, Lenka Styfalova, Stéphane Ruckly, Mathilde Neuville, Aguila Radjou, Jordane Lebut, Marie-Pierre Dilly, Bruno Mourvillier, Richard Dorent, Patrick Nataf, Michel Wolff, Jean-François Timsit
BACKGROUND: Infectious complications are a major cause of morbidity and mortality after heart transplantation (HT). However, the epidemiology and outcomes of these infections in the recent population of adult heart transplant recipients have not been investigated. METHODS: We conducted a single-center retrospective study on infectious complications occurring within 180 days following HT on consecutive heart transplant recipients, from January 2011 to June 2015 at Bichat University Hospital in Paris, France...
January 25, 2019: Annals of Intensive Care
https://read.qxmd.com/read/30673888/concurrent-initiation-of-intra-aortic-balloon-pumping-with-extracorporeal-membrane-oxygenation-reduced-in-hospital-mortality-in-postcardiotomy-cardiogenic-shock
#15
Kai Chen, Jianfeng Hou, Hanwei Tang, Shengshou Hu
BACKGROUND: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is widely used in postcardiotomy cardiac shock (PCS). The factors that affect mortality in patients who receive ECMO for PCS remain unclear. In this study, we analyzed the outcomes, predictive factors and complications of ECMO use for PCS. METHODS: A total of 152 adult subjects who received VA-ECMO for PCS in Fuwai Hospital were consecutively included. We retrospectively collected the baseline characteristics, outcomes and complications...
January 23, 2019: Annals of Intensive Care
https://read.qxmd.com/read/30671750/lung-recruitment-what-has-computed-tomography-taught-us-in-the-last-decade
#16
EDITORIAL
D Chiumello, P Formenti, S Coppola
Although chest X-ray remains a fundamental lung imaging technique, through the years, CT scan has significantly improved our knowledge of the pathophysiological process and currently is the reference lung imaging tool for both a visual and quantitative computer-based analysis. The application of lung CT in the early phase of ARDS has led to changes in the clinical management in up of thirty percent of the patients. Although CT requires the transportation of the patient to the radiological department and exposes the patient to high dose of radiation, given the several information that CT can offer, it should be applied at least one time, in the early phase in all ARDS patients...
January 22, 2019: Annals of Intensive Care
https://read.qxmd.com/read/30671726/experts-guidelines-of-intubation-and-extubation-of-the-icu-patient-of-french-society-of-anaesthesia-and-intensive-care-medicine-sfar-and-french-speaking-intensive-care-society-srlf-in-collaboration-with-the-pediatric-association-of-french-speaking-anaesthetists
#17
Hervé Quintard, Erwan l'Her, Julien Pottecher, Frédéric Adnet, Jean-Michel Constantin, Audrey De Jong, Pierre Diemunsch, Rose Fesseau, Anne Freynet, Christophe Girault, Christophe Guitton, Yann Hamonic, Eric Maury, Armand Mekontso-Dessap, Fabrice Michel, Paul Nolent, Sébastien Perbet, Gwenael Prat, Antoine Roquilly, Karim Tazarourte, Nicolas Terzi, Arnaud W Thille, Mikael Alves, Etienne Gayat, Laurence Donetti
BACKGROUND: Intubation and extubation of ventilated patients are not risk-free procedures in the intensive care unit (ICU) and can be associated with morbidity and mortality. Intubation in the ICU is frequently required in emergency situations for patients with an unstable cardiovascular or respiratory system. Under these circumstances, it is a high-risk procedure with life-threatening complications (20-50%). Moreover, technical problems can also give rise to complications and several new techniques, such as videolaryngoscopy, have been developed recently...
January 22, 2019: Annals of Intensive Care
https://read.qxmd.com/read/30671705/admission-to-the-intensive-care-unit-the-need-to-study-complexity-and-solutions
#18
LETTER
Ashraf Roshdy
No abstract text is available yet for this article.
January 22, 2019: Annals of Intensive Care
https://read.qxmd.com/read/30671679/nutri-reaped-study-nutritional-assessment-of-french-critically-ill-children-and-nutrition-practice-survey-in-french-speaking-pediatric-intensive-care-units
#19
Aurélien Jacquot, Frédéric Victor Valla, Thibault Mura, Lyvonne Nicole Tume, Héléna Bertet, Carole Ford-Chessel, Christophe Milesi, Gilles Cambonie, Arnaud De Luca, Bénédicte Gaillard-Le Roux
BACKGROUND: Impaired nutritional status is adversely associated with suboptimal outcomes in critically ill children. Undernutrition at pediatric intensive care unit (PICU) admission ranges from 15 to 65%. A lack of knowledge of the nutritional status of children in French PICUs prevents us from specifically targeting education. This study aims to describe the nutritional status of children in French PICUs and to assess nutritional practices and physicians' knowledge of nutrition, in order to focus NutriSIP (the French-speaking PICU nutrition group) future education programs...
January 22, 2019: Annals of Intensive Care
https://read.qxmd.com/read/30666519/correction-to-hypoxemia-in-the-icu-prevalence-treatment-and-outcome
#20
(no author information available yet)
Following publication of the original article [1], we have been notified that only the 11 members of the writing committee are listed as the collaborators of the SRLF Trial group.
January 21, 2019: Annals of Intensive Care
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