journal
https://read.qxmd.com/read/37388810/management-of-hereditary-angioedema-in-resource-constrained-settings-a-consensus-statement-from-indian-subcontinent
#41
JOURNAL ARTICLE
Ankur Kumar Jindal, Archan Sil, Ridhima Aggarwal, Keshavamurthy Vinay, Anuradha Bishnoi, Deepti Suri, Amit Rawat, Muthu Sendhil Kumaran, Biman Saikia, Rashmi Sarkar, Lalit Gupta, D Dinesh Kumar, Rashmi Jindal, T U Sukumaran, Jose Ouseph, Hilary Longhurst, Ruby Pawankar, Surjit Singh, Sunil Dogra
Hereditary angioedema (HAE) is an uncommon disorder characterized clinically by recurrent episodes of nonitchy subcutaneous and/or submucosal swellings. The estimated prevalence of HAE is ~ 1: 10,000 to 1: 50,000. There are no prevalence data from India, however, estimates suggest that there are 27,000 to 135,000 patients with HAE in India at present. The majority of these, however, remain undiagnosed. Replacement of plasma-derived or recombinant C1-esterase inhibitor (C1-INH) protein, administered intravenously, is the treatment of choice during the management of acute episodes of angioedema (i...
June 2023: Asia Pacific Allergy
https://read.qxmd.com/read/37389101/association-between-prenatal-and-neonatal-risk-factors-and-development-of-bronchiolitis-in-early-life
#42
JOURNAL ARTICLE
Po-Sung Chen, Yi-Fen Tsai, Hong-Ren Yu, Chih-Hsing Hung, Wei-Yu Chen, Ching-Wei Lin, Ju Lee, Chih-An Chen, Hui-Ju Tsai, Jiu-Yao Wang
UNLABELLED: Bronchiolitis is the most common seasonal viral respiratory disorder in infants. However, risk factors for the development of bronchiolitis, particularly during pregnancy, remain unclear. METHODS: A questionnaire was administered to the parents of the hospitalized infants with acute bronchiolitis to obtain information regarding patients' medical, family, and prenatal exposure history. Logistic regression with adjustment was performed to evaluate risk factors associated with bronchiolitis in the infants...
March 2023: Asia Pacific Allergy
https://read.qxmd.com/read/37389100/real-world-data-a-relevant-component-in-the-framework-of-scientific-evidence
#43
REVIEW
Giorgio W Canonica, Lorenzo Del Moro, Giovanni Costanzo, Emanuele Nappi, Giovanni Paoletti
Explanatory randomized controlled clinical trials test hypotheses to see if the intervention causes an outcome of interest in optimal circumstances, that is, established by selecting patients based on inclusion and exclusion criteria and controlled environments. They assess the "efficacy" of an intervention. On the contrary, it is crucial for society to address issues related to real-world clinical practices. This need can be fulfilled by real-world studies. We discuss the challenges in obtaining real-world evidence in asthma, debating the importance of including patients who are typically excluded from randomized controlled clinical trials to ensure the generalizability of the results...
March 2023: Asia Pacific Allergy
https://read.qxmd.com/read/37389099/a-new-journey-of-asia-pacific-allergy
#44
EDITORIAL
Ruby Pawankar, Luo Zhang
No abstract text is available yet for this article.
March 2023: Asia Pacific Allergy
https://read.qxmd.com/read/37389098/covid-19-in-the-asia-pacific-impact-on-climate-change-allergic-diseases-and-one-health
#45
REVIEW
Ruby Pawankar, Bernard Y Thong, Marysia T Recto, Jiu-Yao Wang, Amir Hamzah Abdul Latiff, Ting-Fan Leung, Philip H Li, Rommel Crisenio M Lobo, Michela Lucas, Jae-Won Oh, Wasu Kamchaisatian, Mizuho Nagao, Iris Rengganis, Zarir F Udwadia, Raja Dhar, Sonomjamts Munkhbayarlakh, Logii Narantsetseg, Duy L Pham, Yuan Zhang, Luo Zhang
Climate change and environmental factors such as air pollution and loss of biodiversity are known to have a major impact not only on allergic diseases but also on many noncommunicable diseases. Coronavirus disease 2019 (COVID-19) resulted in many environmental changes during the different phases of the pandemic. The use of face masks, enhanced hand hygiene with hand rubs and sanitizers, use of personal protective equipment (gowns and gloves), and safe-distancing measures, reduced the overall incidence of respiratory infections and other communicable diseases...
March 2023: Asia Pacific Allergy
https://read.qxmd.com/read/37389097/thyroid-disease-post-covid-19-infection-report-of-a-case-with-new-onset-autoimmune-thyroid-disease
#46
Anh Ngoc Trinh, Kim Han Nguyen, Dinh Van Nguyen
We present hyperthyroidism with autoimmune thyroid disease, which developed a few weeks after the COVID-19 infection in a patient with no prior thyroid disease. Our case was described with clinical presentations, diagnostic tests, and subsequent patient management and compared to other similar reported cases. A 28-year-old female patient with no prior history of thyroid dysfunction developed hyperthyroidism 8 weeks after COVID-19 infection, confirmed by low thyroid stimulating hormone, high free thyroxine 4, and thyroid receptor antibody...
March 2023: Asia Pacific Allergy
https://read.qxmd.com/read/37389096/the-epithelial-barrier-theory-development-and-exacerbation-of-allergic-and-other-chronic-inflammatory-diseases
#47
REVIEW
Umut Can Kucuksezer, Cevdet Ozdemir, Duygu Yazici, Yagiz Pat, Yasutaka Mitamura, Manru Li, Na Sun, Paolo D'Avino, Xiangting Bu, Xueyi Zhu, Mubeccel Akdis, Kari Nadeau, Ismail Ogulur, Cezmi A Akdis
It is now longer than half a century, humans, animals, and nature of the world are under the influence of exposure to many newly introduced noxious substances. These exposures are nowadays pushing the borders to be considered as the causative or exacerbating factors for many chronic disorders including allergic, autoimmune/inflammatory, and metabolic diseases. The epithelial linings serve as the outermost body's primary physical, chemical, and immunological barriers against external stimuli. The "epithelial barrier theory" hypothesizes that these diseases are aggravated by an ongoing periepithelial inflammation triggered by exposure to a wide range of epithelial barrier-damaging insults that lead to "epithelitis" and the release of alarmins...
March 2023: Asia Pacific Allergy
https://read.qxmd.com/read/37389095/immunological-dysfunction-and-mast-cell-activation-syndrome-in-long-covid
#48
REVIEW
Stevent Sumantri, Iris Rengganis
At least 65 million people around the world suffer from long COVID-19, with the majority of cases occurring in the productive age (36-50 years old). Individuals with long COVID-19 are confounded with multiple organ system dysfunctions, long-term organ injury sequelae, and a decreased quality of life. There is an overlapping of risk factors between long COVID-19 and other postviral infection syndromes, so advances in research could also benefit other groups of patients. Long COVID-19 is the consequence of multiple immune system dysregulation, such as T-cell depletion, innate immune cell hyperactivity, lack of naive T and B cells, and elevated signature of pro-inflammatory cytokines, together with persistent severe acute respiratory syndrome-coronavirus 2 reservoir and other consequences of acute infection...
March 2023: Asia Pacific Allergy
https://read.qxmd.com/read/37389094/validation-of-the-chinese-drug-hypersensitivity-quality-of-life-questionnaire-role-of-delabeling
#49
JOURNAL ARTICLE
Hugo W F Mak, Elsie T S Chan, Jackie S H Yim, Elaine Lee, Dorothy L Y Lam, Valerie Chiang, Philip H Li
UNLABELLED: The Drug Hypersensitivity Quality of Life Questionnaire (DrHy-Q) is not currently available in Chinese. Besides, penicillin allergy (PA) is a worldwide public health challenge, and delabeling inauthentic PA can improve clinical and economic outcomes. However, its effect on health-related quality of life (HRQoL) remains poorly known. OBJECTIVE: The study objective is to translate and validate a Chinese version of DrHy-Q and investigate the effect of PA delabeling on HRQoL using DrHy-Q...
March 2023: Asia Pacific Allergy
https://read.qxmd.com/read/37389093/food-allergy-prevention-where-are-we-in-2023
#50
REVIEW
Carina Venter, Peter K Smith, David M Fleischer
Food allergy prevention involves recommendations to the maternal diet during pregnancy and breast feeding, early life feeding and introduction of solid foods. Pregnant and breastfeeding women are not recommended to exclude any food allergens from their diet, but data are lacking to support active consumption of food allergens for prevention of food allergy. Breastfeeding is recommended for the many health benefits to the mother and child but has not shown any association with reduction in childhood food allergies...
March 2023: Asia Pacific Allergy
https://read.qxmd.com/read/36452020/measures-for-food-allergy-emergency-in-nurseries
#51
JOURNAL ARTICLE
Mitsunobu Kaneko, Tomoko Miyoshi, Yoshihiro Miyashita, Riku Hayashi, Takuji Hashimoto
BACKGROUND: As food allergy potentially can induce life-threatening anaphylaxis, measures for food allergy are required at nurseries caring for food allergy children, but a large-scale factual investigation has not been carried out. OBJECTIVE: We evaluated measures for food allergy emergency in nurseries. METHODS: A questionnaire survey regarding emergency measures in all authorized nurseries (411 facilities including 20,586 children) was conducted in Kawasaki city, Japan...
October 2022: Asia Pacific Allergy
https://read.qxmd.com/read/36452019/severe-chronic-cough-relating-to-post-covid-19-interstitial-lung-disease-a-case-report
#52
Lam Nguyen-Ho, Vinh Nguyen-Nhu, Thuy-Tuong Tran-Thi, Joshua J Solomon
Cough is a common symptom occurring in patients with acute coronavirus disease 2019 (COVID-19) infection as well as during the post-COVID-19 period. The post-COVID-19 cough can improve over time and the incidence of sustained post-COVID-19 chronic cough is low. Approaching post-COVID-19 cough is challenging to clinicians including pulmonologists and allergists due to a diverse set of etiologies and the lack of published guidance on effective treatments. A 60-year-old male ex-smoker presented to the outpatient long COVID-19 clinic because of a prolonged cough for 4 months after a severe COVID-19 infection...
October 2022: Asia Pacific Allergy
https://read.qxmd.com/read/36452018/identification-of-fungi-causing-humidifier-lung-2-rare-cases-and-a-review-of-the-literature
#53
JOURNAL ARTICLE
Kai Ryu, Yuma Fukutomi, Kiyoshi Sekiya, Akemi Saito, Yuto Hamada, Kentaro Watai, Yosuke Kamide, Masami Taniguchi, Jun Araya, Kazuyoshi Kuwano, Katsuhiko Kamei
BACKGROUND: Humidifier lung (HL) is a hypersensitivity pneumonitis resulting from exposure to humidifiers, with fungi from the humidifier as one of the etiologic agents. However, identification of the fungal species responsible for each case can be challenging because of difficulties in culturing fungi, their accurate identification, and interpreting the results of specific serum IgG testing. OBJECTIVE: To clarify the best way to determine the causative fungal species of each HL case...
October 2022: Asia Pacific Allergy
https://read.qxmd.com/read/36452017/natural-history-and-clinical-course-of-patients-with-dermographism-in-a-tropical-country-a-questionnaire-based-survey
#54
JOURNAL ARTICLE
Chuda Rujitharanawong, Papapit Tuchinda, Leena Chularojanamontri, Yanisorn Nanchaipruek, Nuttagarn Jantanapornchai, Visanu Thamlikitkul, Kanokvalai Kulthanan
BACKGROUND: Dermographism is the most common form of chronic inducible urticaria. However, the natural history and clinical course of patients with dermographism in tropical countries has not fully been described. OBJECTIVE: To examine clinical features, natural history and clinical course of dermographism in Thai patients according to their experiences. METHODS: A cross-sectional, internet-based survey was conducted in 2021. All study respondents completed a 45-item questionnaire that was circulated on social media regarding dermographism...
October 2022: Asia Pacific Allergy
https://read.qxmd.com/read/36452016/mechanisms-and-biomarkers-of-successful-allergen-specific-immunotherapy
#55
REVIEW
Juan-Felipe López, Manal Bel Imam, Pattraporn Satitsuksanoa, Sophieke Lems, Minglin Yang, Yu-Kyoung Hwang, Purevsuren Losol, Jun-Pyo Choi, Sae-Hoon Kim, Yoon-Seok Chang, Mübeccel Akdis, Cezmi A Akdis, Willem van de Veen
Allergen-specific immunotherapy (AIT) is considered the only curative treatment for allergic diseases mediated by immunoglobulin E (IgE). Currently, the route of administration depends both on the different types of causal allergens and on its effectiveness and safety profile. Several studies have reported the mechanisms and changes in humoral and cellular response underlying AIT; however, the full picture remains unknown. Knowledge of who can benefit from this type of treatment is urgently needed due to the patient safety risks and costs of AIT...
October 2022: Asia Pacific Allergy
https://read.qxmd.com/read/36452015/the-melbourne-epidemic-thunderstorm-asthma-event-2016-a-5-year-longitudinal-study
#56
JOURNAL ARTICLE
Felicity Huang, David H Wang, Chuan T Foo, Alan C Young, Jie Shen Fok, Francis Thien
BACKGROUND: In 2016, Melbourne was struck by the world's largest and most devastating epidemic thunderstorm asthma (ETSA) episode. While affected individuals displayed worsened short-term asthma control, little is known about their longer-term natural history, nor about interventions that restore control. OBJECTIVE: We assessed the asthma symptomatology and related behaviours of ETSA-affected individuals through a single-centre prospective 5-year longitudinal study...
October 2022: Asia Pacific Allergy
https://read.qxmd.com/read/36452014/how-physicians-approach-hereditary-angioedema-a-single-center-study
#57
JOURNAL ARTICLE
Kadriye Terzioglu, Dane Ediger, Ebru Ozdemir, Raziye TulumenOzturk, Fatma Oflu Dogan, Ozgur Sancar
BACKGROUND: Hereditary angioedema (HAE) is a rare autosomal dominant disorder caused by C1-inhibitor deficiency. It is characterized by recurrent attacks of cutaneous and upper respiratory tract swelling, and abdominal pain due to mucosal edema. Early detection and treatment prevent unnecessary interventions, improves quality of life, and prevents potentially fatal attacks. OBJECTIVE: The present study aims to investigate physicians level of knowledge and awareness regarding HAE...
October 2022: Asia Pacific Allergy
https://read.qxmd.com/read/36452013/erratum-change-original-to-characteristics-of-the-european-thoracic-society-american-thoracic-society-severe-asthma-definition-as-a-determinant-of-future-use-of-biologics-bronchial-thermoplasty
#58
Hirono Nishiyama, Yoshihiro Kanemitsu, Kensuke Fukumitsu, Norihisa Takeda, Ryota Kurokawa, Tomoko Tajiri, Keima Ito, Jenifer Maries Go Yap, Satoshi Fukuda, Takehiro Uemura, Hirotsugu Ohkubo, Ken Maeno, Yutaka Ito, Tetsuya Oguri, Masaya Takemura, Akio Niimi
[This corrects the article e13 in vol. 12, PMID: 35571548.].
October 2022: Asia Pacific Allergy
https://read.qxmd.com/read/36452012/level-of-knowledge-among-healthcare-professionals-regarding-anaphylaxis
#59
JOURNAL ARTICLE
Sevgi Sipahi Cimen, Sena Baykara Sayili
BACKGROUND: Anaphylaxis is defined as a severe, life-threatening systemic hypersensitivity reaction. Healthcare professionals must recognize the symptoms, apply correct treatment immediately, and provide epinephrine auto-injectors (EAI) to patients who experience anaphylaxis. OBJECTIVE: In this study, we aimed to investigate the knowledge of healthcare professionals regarding anaphylaxis. METHODS: This cross-sectional study, which was conducted between February 2022 and March 2022, included healthcare professionals working in various hospitals in Turkey...
October 2022: Asia Pacific Allergy
https://read.qxmd.com/read/36452011/case-of-hypereosinophilic-syndrome-with-gastrointestinal-involvement-showing-tissue-eosinophil-cytolysis
#60
Shin-Ichiro Hagiwara, Shigeharu Ueki, Ken Watanabe, Keinosuke Hizuka, Yuri Etani
Hypereosinophilic syndrome (HES), which is characterized by eosinophilia in the peripheral blood, often causes various organ disorders, including those of the gastrointestinal (GI) tract. The eosinophils play a key role in inflammation in eosinophilic GI disorders (EGIDs), including HES with GI involvement. Here, we report a case of HES with GI involvement that showed major basic proteins (MBPs) deposition in the absence of marked eosinophilic infiltration in the mucosa of the GI tract. An 11-year-old boy presented with nausea and epigastric pain for one week...
October 2022: Asia Pacific Allergy
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