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Clinical Obesity

Osama M Moussa, Maddalena Ardissino, Priyantha Kulatilake, Ara Faraj, Elisabetta Muttoni, Ara Darzi, Paul Ziprin, Samantha Scholtz, Sanjay Purkayastha
With obesity levels increasing, it is important to consider the mental health risks associated with this condition to optimize patient care. Links between depression and obesity have been explored, but few studies focus on the risk profiles of patients across stratified body mass index (BMI) classes above 30 kg/m2 . This study aims to determine the impact of BMI on depression risk in patients with obesity and to investigate trends of depression in a large cohort of British patients with BMI > 30 kg/m2 . A nationwide primary care database, the Clinical Practice Research Datalink (CPRD), was analysed for diagnoses of obesity (BMI > 30 kg/m2 )...
March 5, 2019: Clinical Obesity
George Mawardi, Elizabeth B Kirkland, Jingwen Zhang, Devin Blankinship, Marc E Heincelman, Andrew D Schreiner, William P Moran, Samuel O Schumann
As the prevalence of obesity increases, the prevalence of associated comorbid diseases, obesity-related mortality rates and healthcare costs rise concordantly. Two main factors that hinder efforts to treat obesity include a lack of recognition by patients and documentation by physicians. This study evaluates the relationship between patient perception of obese weight and physician documentation of obesity. This quality improvement observational study surveyed patients of an academic internal medicine clinic on their perception of obesity...
February 27, 2019: Clinical Obesity
Michiel P B Moonen, Emmani B M Nascimento, Marinus J P G van Kroonenburgh, Dees Brandjes, Wouter D van Marken Lichtenbelt
Madelung's disease is characterized by the manifestation of multiple ectopic lipomas, usually found in the cervical-thoracic region, however, clinical manifestation may vary among patients. It has been postulated that lipomas associated with Madelung's disease are linked to brown adipose tissue (BAT) due to the presence of uncoupling protein 1 (UCP1). Therefore, we here investigated whether BAT activity is present in a patient with Madelung's disease. 18 F-fluorodeoxyglucose (18 F-FDG) uptake using PET/CT after a cooling procedure was measured together with body temperature and energy expenditure...
February 27, 2019: Clinical Obesity
Georgia Katsogridaki, George Tzovaras, Eleni Sioka, Konstantinos Perivoliotis, Eleni Zachari, Dimitrios Magouliotis, Vassiliki Tasiopoulou, Dimitrios Zacharoulis
The aim of this study was to evaluate the prevalence of hyperuricemia and acute gout after laparoscopic sleeve gastrectomy (LSG). Risk factors for developing gout were also examined. Eighty-five patients underwent LSG were enrolled in this prospective study. Serum uric acid levels, gout attacks and total water levels % derived by bioimpedance were examined pre-operatively and 1 month post-operatively. Hyperuricemia was identified in 30.6% pre-operatively and in 18.82% of patients post-operatively. From the patients' group with pre-operative hyperuricemia, 53...
February 27, 2019: Clinical Obesity
Diana P Brostow, Theodore J Warsavage, Lauren M Abbate, Amy J Starosta, Lisa A Brenner, Mary E Plomondon, Javier A Valle
Mental illness and obesity are highly prevalent in patients with coronary disease and are frequently comorbid. While mental illness is an established risk factor for major adverse cardiac and cerebrovascular events (MACCEs), prior studies suggest improved outcomes in people with obesity. It is unknown if obesity and mental illness interact to affect cardiac outcomes or if they independently influence MACCE. We identified 55 091 patients undergoing percutaneous coronary intervention (PCI) between 2009 and 2014, using the Veterans Affairs (VA) Clinical Assessment Reporting and Tracking (CART) program...
February 21, 2019: Clinical Obesity
Biagina-Carla Farnesi, Arnaldo Perez, Nicholas L Holt, Katherine M Morrison, Rebecca Gokiert, Laurent Legault, Jean-Pierre Chanoine, Arya M Sharma, Geoff D C Ball
Although prolonged engagement in paediatric weight management (PWM) is associated with positive treatment outcomes, little is currently known about enablers of long-term programme attendance. The purpose of our study was to explore families' reasons for and facilitators of their continued attendance at health services for PWM. Semi-structured, individual interviews were conducted with parents of children (10-17 year old; body mass index ≥85th percentile) who completed the active phase of treatment in one of four Canadian multidisciplinary clinics for PWM...
February 18, 2019: Clinical Obesity
Divya Ramachandran, Evan Atlantis, Tania Markovic, Samantha Hocking, Timothy Gill
We aimed to develop an expert consensus on standardizing data collections in specialist obesity management clinics in Australia. A panel of 16 experts participated in a structured consensus-driven Delphi process to reach agreement on a minimum set of baseline patient data collections for consideration in specialist obesity services. The panel included surgeons, clinicians, allied health professionals (dietician, exercise physiologist, psychologist), a bariatric nurse and obesity researchers. We produced a recommended list of core and useful data items that should comprise the baseline patient data set...
February 13, 2019: Clinical Obesity
Michael Vallis
The purpose of this study was to report on a nationally representative survey of the experience of Canadian adults regarding food cravings and the impact of these cravings on behaviour and quality of life. A total of 1532 respondents (16% of members of an online panel emailed an invitation and link) completed a nationally distributed survey. Almost two-thirds of the sample reported experiencing cravings, with women being more likely to report cravings than men. Of those with cravings, 83.1% reported moderate or strong cravings...
February 11, 2019: Clinical Obesity
Kara J Kallies, Andrew J Borgert, Shanu N Kothari
As the rate of obesity continues to rise, primary care providers (PCPs) must be aware and informed of the treatment options available. Bariatric surgery is the most effective long-term treatment for weight loss and improvement of obesity-related comorbidities. The aim of this study was to assess patients' perception of their PCP's opinion, support and knowledge of bariatric surgery and changes over time. In 2009 and 2015, a 27-question survey was developed and mailed to patients who had undergone laparoscopic Roux-en-Y gastric bypass (LRYGB) at our institution...
February 1, 2019: Clinical Obesity
Shulamit Geller, Sigal Levy, Gil Goldzweig, Sami Hamdan, Anat Manor, Shiran Dahan, Eyal Rothschild, Yelena Stukalin, Subhi Abu-Abeid
The increased risk of psychological distress among bariatric surgery candidates may be attributed, at least in part, to body image dissatisfaction (BID). The aim of the present study was to test the hypotheses that body image could be correlated with the psychological distress variables, and that emotional eating behaviours could mediate the relationship between body image and psychological distress. A sample of consecutive participants seeking bariatric surgery (N = 169, 67% females, mean age, 41.8 years [SD = 11...
February 1, 2019: Clinical Obesity
Ahmed Ghachem, Maimouna Bagna, Hélène Payette, Pierrette Gaudreau, Martin Brochu, Isabelle J Dionne
Obesity in older adults results from several interacting factors. Consequently, interventions have shown mitigated effects. We determined (a) the different subgroups of older adults with obesity based on clusters of associated comorbidities and (b) the trajectory of these clusters to assess their stability over 3 years and factors contributing to transitions. Obese men (n = 193; body mass index [BMI] = 33.15 ± 2.69 kg/m2 ) and women (n = 220; BMI = 33.71 ± 3.71 kg/m2 ) aged between 68 and 82 years were studied...
January 29, 2019: Clinical Obesity
Eric A Finkelstein, Naina R Verghese
Recent medical advancements have led to new modes of treatment for non-surgical weight loss, including several new medications. Our aim was to conduct an incremental cost-effectiveness analysis for all commercially available, evidence-based non-surgical weight loss interventions for people with excess weight. We identified interventions through a systematic review of randomized controlled trials that reported weight loss 12 months from baseline. We then meta-analysed the results, sourced costs and performed an incremental cost-effectiveness analysis from the payer perspective...
January 24, 2019: Clinical Obesity
Kathryn Rock, Richard D Hayward, Elango Edhayan
Traumatic injury is a leading cause of death and disability worldwide. Obesity may put trauma patients at risk for complications leading to negative clinical outcomes. Data on all hospital admissions due to traumatic injury in the Detroit metropolitan area between 2006 and 2014 were obtained from the Michigan State Inpatient Database. Generalized linear modelling was used to compare patients with and without obesity on three outcomes: mortality, length of hospital stay and total charges for care. Adjusting for demographics, patients with obesity had 26% longer hospitalization...
January 18, 2019: Clinical Obesity
Helen Moffat, Fiona Campbell, Claire Donald, Pauline Insch, Sophie Little, Susan Logan, Mary McCallum
There is limited evidence of the effectiveness of non-surgical interventions for severe obesity. Our aim was to evaluate a group intervention delivered by a National Health Service (NHS) specialist weight management service to contribute to the evidence base and inform the development of future services. Participants in this prospective cohort study were patients attending NHS Grampian Specialist Weight Management Services. The intervention was an interactive 12-session group programme based on evidence-based psychological model, with combined dietetic and psychological knowledge and support provided...
December 27, 2018: Clinical Obesity
J Austin, C Smith, K Natarajan, M Som, C Wayant, M Vassar
This is a cross-sectional analysis of spin in randomized controlled trial (RCT) abstracts published in top-ranked obesity and general medicine journals. The top seven obesity and four general medicine journals were searched from 1 January 2016 to 31 December 2017. To be included in this study, a trial must be an RCT with non-significant primary endpoint (P > 0.05), exclusively randomize subjects with overweight or obesity or have a primary endpoint of weight loss. These studies were analysed by two reviewers for spin in the abstract...
December 21, 2018: Clinical Obesity
P Rye, R Modi, A M Sharma
No abstract text is available yet for this article.
December 2018: Clinical Obesity
T Luig, R Anderson, A M Sharma, D L Campbell-Scherer
Obesity is a complex, chronic disease, frequently associated with multiple comorbidities. Its management is hampered by a lack of translation of evidence on chronicity and pathophysiology into clinical practice. Also, it is not well understood how to support effective provider-patient communication that adequately addresses patients' personal root causes and barriers and helps them feel capable to take action for their health. This study examined interpersonal processes during clinical consultations, their impacts, and outcomes with the aim to develop an approach to personalized obesity assessment and care planning...
December 2018: Clinical Obesity
A M Chao, T A Wadden, R L Pearl, N Alamuddin, S M Leonard, Z M Bakizada, E Pinkasavage, K A Gruber, O A Walsh, R I Berkowitz, N Alfaris, J S Tronieri
Anti-obesity medication may help people maintain diet-induced reductions in appetite. The present exploratory analysis assessed the effects of lorcaserin on changes at 24 weeks post-randomization in emotion- and stress-related eating, food cravings and other measures of appetite (i.e. binge eating, cognitive restraint, disinhibition, hunger, preoccupation with eating and fullness). The parent study investigated the efficacy of combined lorcaserin and behavioural treatment in facilitating weight loss maintenance (WLM) in 137 adults (mean age = 46...
December 2018: Clinical Obesity
B Lascaris, S Pouwels, P Houthuizen, L R Dekker, S W Nienhuijs, R A Bouwman, M P Buise
Obesity, defined as a body mass index of ≥30 kg/m2 , is the most common chronic metabolic disease worldwide and its prevalence has been strongly increasing. Obesity has deleterious effects on cardiac function. The purpose of this review is to evaluate the effects of obesity and excessive weight loss due to bariatric surgery on cardiac function, structural changes and haemodynamic responses of both the left and right ventricle.
December 2018: Clinical Obesity
D E Magouliotis, V S Tasiopoulou, K A Svokos, A A Svokos, E Sioka, G Tzovaras, D Zacharoulis
We aim to review the available literature on patients with morbid obesity treated with banded (BRYGB) or non-banded Roux-en-Y gastric bypass (NBRYGB), in order to compare the clinical outcomes and intraoperative parameters of the two methods. A systematic literature search was performed in PubMed, Cochrane library and Scopus databases, in accordance with the PRISMA guidelines. Eight studies met the inclusion criteria incorporating 3899 patients. This study reveals similar rates of complications, mortality, remission of type 2 diabetes, hypertension, dyslipidaemia, gastroesophageal reflux and obstructive sleep apnoea, along with similar % excess weight loss (%EWL) at 1 and 2 years postoperatively...
December 2018: Clinical Obesity
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