journal
https://read.qxmd.com/read/38419958/parallelism-and-non-parallelism-in-diabetic-nephropathy-and-diabetic-retinopathy
#1
REVIEW
Shanshan Tang, Xuedong An, Wenjie Sun, Yuehong Zhang, Cunqing Yang, Xiaomin Kang, Yuting Sun, Linlin Jiang, Xuefei Zhao, Qing Gao, Hangyu Ji, Fengmei Lian
Diabetic nephropathy (DN) and diabetic retinopathy (DR), as microvascular complications of diabetes mellitus, are currently the leading causes of end-stage renal disease (ESRD) and blindness, respectively, in the adult working population, and they are major public health problems with social and economic burdens. The parallelism between the two in the process of occurrence and development manifests in the high overlap of disease-causing risk factors and pathogenesis, high rates of comorbidity, mutually predictive effects, and partial concordance in the clinical use of medications...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38419957/a-comparison-of-the-performance-of-68-ga-pentixafor-pet-ct-versus-adrenal-vein-sampling-for-subtype-diagnosis-in-primary-aldosteronism
#2
JOURNAL ARTICLE
Xuan Yin, Kai Ai, Jianguang Luo, Wei Liu, Xiaowei Ma, Lianbo Zhou, Xin Xiang, Xin Su, Yunhua Wang, Yuan Li
OBJECTIVE: To investigate the diagnostic efficiency and prognostic value of 68 Ga-Pentixafor PET/CT in comparison with adrenal vein sampling (AVS) for functional lateralization in primary aldosteronism (PA). Histology and long-term clinical follow-up normally serve as the gold standard for such diagnosis. METHODS: We prospectively recruited 26 patients diagnosed with PA. All patients underwent 68 Ga-Pentixafor PET/CT and AVS. Postsurgical biochemical and clinical outcomes of patients with unilateral primary aldosteronism (UPA), as diagnosed by PET/CT or AVS, were assessed by applying standardized Primary Aldosteronism Surgical Outcome (PASO) criteria...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38419956/the-combination-of-body-mass-index-and-fasting-plasma-glucose-is-associated-with-type-2-diabetes-mellitus-in-japan-a-secondary-retrospective-analysis
#3
JOURNAL ARTICLE
Xiaofang Zhao, Tianci Yao, Bei Song, Haohui Fan, Ting Liu, Guangyu Gao, Kun Wang, Weilin Lu, Chengyun Liu
BACKGROUND: Body mass index (BMI) and fasting plasma glucose (FPG) are known risk factors for type 2 diabetes mellitus (T2DM), but data on the prospective association of the combination of BMI and FPG with T2DM are limited. This study sought to characterize the association of the combination of BMI and FPG (ByG) with T2DM. METHODS: The current study used the NAGALA database. We categorized participants by tertiles of ByG. The association of ByG with T2DM was expressed with hazard ratios (HRs) with 95% confidence intervals (CIs) after adjustment for potential risk factors...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38419955/association-between-vitamin-d-status-and-cardiometabolic-risk-factors-in-adults-with-type-2-diabetes-in-shenzhen-china
#4
JOURNAL ARTICLE
Yan-Jing Liu, Jing-Wen Duan, Dong-Hui Lu, Fan Zhang, Hong-Li Liu
BACKGROUND: Evidence of vitamin D status and cardiometabolic health in adults with type 2 diabetes mellitus (T2DM) is still limited. This study aimed to investigate the association between vitamin D status and cardiometabolic risk factors among adults with T2DM in Shenzhen, China. METHODS: This cross-sectional study included 164 adults (aged ≥18 years) with T2DM who were hospitalized at Peking University Shenzhen Hospital from March 1, 2023, to May 31, 2023...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38419954/correlation-analysis-of-diabetes-based-on-copula
#5
JOURNAL ARTICLE
Chang Liu, Hu Yang, Junjie Yang, Hongqing Wang
INTRODUCTION: The ratio of Triglyceride (TG) to high-density lipoprotein cholesterol (HDL-C) is a crucial indicator for diabetes diagnosis. METHODS: This study utilizes the Copula function to model and fit the non-linear correlation among fasting blood glucose (Glu), glycosylated hemoglobin (HbA1C), and TG/HDL-C in patients with diabetes. The Copula function chosen for this study includes the two-dimensional Archimedes and Elliptical distribution family, as well as the multidimensional Vine Copula function, for fitting the data...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38419953/thyroid-dysfunction-and-alzheimer-s-disease-a-vicious-circle
#6
REVIEW
Zhaoqing Li, Jia Liu
Recently, research into the link between thyroid dysfunction and Alzheimer's disease (AD) remains a current topic of interest. Previous research has primarily concentrated on examining the impact of thyroid dysfunction on the risk of developing AD, or solely explored the mechanisms of interaction between hypothyroidism and AD, a comprehensive analysis of the mechanisms linking thyroid dysfunction, including hyperthyroidism and hypothyroidism, to Alzheimer's disease (AD) still require further elucidation. Therefore, the aim of this review is to offer a thorough and comprehensive explanation of the potential mechanisms underlying the causal relationship between thyroid dysfunction and AD, highlighting the existence of a vicious circle...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38419952/case-report-uncovering-hidden-glucose-patterns-in-medicated-versus-unmedicated-bipolar-disorder-and-comorbid-type-1-diabetes-mellitus
#7
Dagmar Breznoscakova, Maria Pallayova
INTRODUCTION: Type 1 diabetes mellitus is characterized by an absolute insulin deficiency requiring the lifetime intensive insulin therapy accompanied by daily self-monitoring, self-management, ongoing education, and complex diabetes care. Regular patient-clinician shared therapeutic decisions based on age, sex, comorbidities, medications, predicted impact of meals, physical activity, stress, hormonal changes, insulin therapy, and patterns of glycemic changes are key for achieving glycemic targets...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38419951/glycemic-variability-evaluated-by-hba1c-rather-than-fasting-plasma-glucose-is-associated-with-adverse-cardiovascular-events
#8
JOURNAL ARTICLE
Lijuan Sheng, Guifang Yang, Xiangping Chai, Yang Zhou, Xin Sun, Zhenhua Xing
BACKGROUND: Although studies have shown that glycemic variability is positively associated with an increased risk of cardiovascular disease, few studies have compared hemoglobin A1c (HbA1c) and fasting plasma glucose (FPG) variability with adverse cardiovascular events in patients with type 2 diabetes mellitus (T2DM). METHODS: This was a post hoc analysis of the Action to Control Cardiovascular Risk in Diabetes (ACCORD) study. Cox proportional hazards models were used to explore the relationship between HbA1c or FPG variability and the incidence of major adverse cardiovascular events (MACEs)...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38414824/nonlinear-association-of-the-systemic-immune-inflammatory-index-with-mortality-in-diabetic-patients
#9
JOURNAL ARTICLE
Chunli Meng, Kai Liu
BACKGROUND: It has been demonstrated that in diabetic patients, an elevated neutrophil-lymphocyte ratio (NLR) is independently connected with higher cardiovascular and all-cause mortality. It is unclear, however, if the systemic immune-inflammatory index (SII) and the mortality rate among diabetic patients are related. Investigating the linkage between SII and diabetes patients' risk of cardiovascular and all-cause death was the aim of the study. METHODS: 4972 diabetics who were chosen from six rounds of the National Health and Nutrition Examination Survey (NHANES) between 2005 and 2016 were the study's participants...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38414823/fibrate-and-the-risk-of-cardiovascular-disease-among-moderate-chronic-kidney-disease-patients-with-primary-hypertriglyceridemia
#10
JOURNAL ARTICLE
Chieh-Li Yen, Pei-Chun Fan, Cheng-Chia Lee, Jia-Jin Chen, Chao-Yu Chen, Yi-Ran Tu, Pao-Hsien Chu, Ching-Chung Hsiao, Yung-Chang Chen, Chih-Hsiang Chang
INTRODUCTION: Hypertriglyceridemia is the most prevalent dyslipidemia in patients with chronic kidney disease (CKD). However, research about fibrate treatment in CKD patients is limited, and assessing its benefits becomes challenging due to the frequent concurrent use of statins. Thus, this study is aimed to investigate the role of fibrate in CKD stage 3 patients with hypertriglyceridemia who did not receive other lipid-lowering agents. METHODS: This study enrolled patients newly diagnosed CKD3 with LDL-C<100mg/dL and had never received statin or other lipid-lowering agents from Chang Gung Research Database...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38414822/elevated-triglyceride-glucose-body-mass-index-associated-with-lower-probability-of-future-regression-to-normoglycemia-in-chinese-adults-with-prediabetes-a-5-year-cohort-study
#11
JOURNAL ARTICLE
Yang Shao, Haofei Hu, Changchun Cao, Yong Han, Cen Wu
OBJECTIVE: Despite the clear association of TyG-BMI with prediabetes and the progression of diabetes, no study to date has examined the relationship between TyG-BMI and the reversal of prediabetes to normoglycemia. METHODS: 25,279 participants with prediabetes who had physical examinations between 2010 and 2016 were enrolled in this retrospective cohort study. The relationship between baseline TyG-BMI and regression to normoglycemia from prediabetes was examined using the Cox proportional hazards regression model in this study...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38414821/burden-of-psoriasis-in-young-adults-worldwide-from-the-global-burden-of-disease-study-2019
#12
JOURNAL ARTICLE
Yuanchen Zhang, Shuai Dong, Yuan Ma, Yan Mou
BACKGROUND: To determine the global burden of psoriasis in young adults, i.e., those aged 15-49, from 1990 to 2019 and predict trends in this burden for 2020 to 2030. METHODS: Age-standardized disease burden indicators and their estimated annual percentage changes were assessed and used to compare the estimated burden between regions. In addition, generalized additive models were used to predict the burden in this population from 2020 to 2030. RESULTS: From 1990 to 2019, the overall burden of psoriasis in young adults worldwide trended downward, as the age-standardized incidence rate and the age-standardized disability-adjusted life year rate decreased...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38414820/editorial-cardiovascular-diseases-related-to-diabetes-and-obesity-volume-iii
#13
EDITORIAL
Ying Xin, Jamie Young Wise, Mohanraj Rajesh, Lu Cai
No abstract text is available yet for this article.
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38414819/retraction-shcbp1-promotes-papillary-thyroid-carcinoma-carcinogenesis-and-progression-through-promoting-formation-of-integrin-and-collagen-and-maintaining-cell-stemness
#14
(no author information available yet)
[This retracts the article DOI: 10.3389/fendo.2020.613879.].
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38414818/differential-effects-of-fish-oil-and-cocoa-butter-based-high-fat-high-sucrose-diets-on-endocrine-pancreas-morphology-and-function-in-mice
#15
JOURNAL ARTICLE
Shaima Albeloushi, Amal Hasan, Hossein Arefanian, Sardar Sindhu, Fatema Al-Rashed, Shihab Kochumon, Nermeen Abukhalaf, Texy Jacob, Steve Shenouda, Ashraf Al Madhoun, Fahd Al-Mulla, Rasheed Ahmad
INTRODUCTION: A high-fat/high-sucrose diet leads to adverse metabolic changes that affect insulin sensitivity, function, and secretion. The source of fat in the diet might inhibit or increase this adverse effect. Fish oil and cocoa butter are a significant part of our diets. Yet comparisons of these commonly used fat sources with high sucrose on pancreas morphology and function are not made. This study investigated the comparative effects of a fish oil-based high-fat/high-sucrose diet (Fish-HFDS) versus a cocoa butter-based high-fat/high-sucrose diet (Cocoa-HFDS) on endocrine pancreas morphology and function in mice...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38410698/effects-of-different-gonadotropin-preparations-in-gnrh-antagonist-protocol-for-patients-with-polycystic-ovary-syndrome-during-ivf-icsi-a-retrospective-cohort-study
#16
JOURNAL ARTICLE
Zhengyan Hu, Rujun Zeng, Rui Gao, Mingli Chen, Xiumei Liu, Qiong Zhang, Lang Qin, Xun Zeng
PURPOSE: To compare the effects of recombinant FSH alfa (rFSH-alfa), rFSH-beta, highly purified human menopausal gonadotropin (HP-hMG) and urinary FSH (uFSH) in women with polycystic ovarian syndrome who have undertaken the GnRH antagonist protocol during IVF/ICSI treatment. METHOD: A single-center retrospective cohort study including women with PCOS who received the GnRH antagonist protocol from January 2019 to July 2022 was conducted. Patients were divided into rFSH-alfa group, HP-hMG group, uFSH group, and rFSH-beta group, and the number of oocytes retrieved, clinical pregnancy rate of the fresh cycle (primary outcomes), embryo quality, and severe OHSS rate (secondary outcomes) were compared...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38410697/non-linear-associations-of-cardiometabolic-index-with-insulin-resistance-impaired-fasting-glucose-and-type-2-diabetes-among-us-adults-a-cross-sectional-study
#17
JOURNAL ARTICLE
Jimei Song, Yimei Li, Junxia Zhu, Jian Liang, Shan Xue, Zhangzhi Zhu
BACKGROUND: Cardiometabolic index (CMI) is a novel indicator for predicting the risk of obesity-related diseases. We aimed to determine the relationships of CMI with insulin resistance (IR), impaired fasting glucose (IFG), and type 2 diabetes mellitus (T2DM) using NHANES data from 1999 to 2020. METHODS: After CMI values were estimated, weighted univariate and multivariate logistic regression analyses were used to ascertain whether CMI was an independent risk indicator for IR, IFG, and T2DM...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38410696/expression-and-localization-of-hpg-axis-related-genes-in-carassius-auratus-with-different-ploidy
#18
JOURNAL ARTICLE
Xiaowei Xu, Li Yang, Xinyi Deng, Qingwen Xiao, Xu Huang, Chongqing Wang, Yue Zhou, Xiang Luo, Yuxin Zhang, Xidan Xu, Qinbo Qin, Shaojun Liu
INTRODUCTION: In the Dongting water system, the Carassius auratus (Crucian carp) complex is characterized by the coexistence of diploid forms (2n=100, 2nCC) and polyploidy forms. The diploid (2nCC) and triploid C.auratus (3n=150, 3nCC) had the same fertility levels, reaching sexual maturity at one year. METHODS: The nucleotide sequence, gene expression, methylation, and immunofluorescence of the gonadotropin releasing hormone 2( Gnrh2 ), Gonadotropin hormone beta( Gthβ ), and Gonadotropin-releasing hormone receptor( Gthr ) genes pivotal genes of the hypothalamic-pituitary-gonadal (HPG) axis were analyzed...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38405159/triglyceride-glucose-index-change-and-chronic-kidney-disease-progression-in-a-chinese-hypertensive-population
#19
JOURNAL ARTICLE
Chao Yu, Yumeng Shi, Tao Wang, Lingjuan Zhu, Wei Zhou, Huihui Bao, Xiaoshu Cheng
BACKGROUND: The impact of triglyceride-glucose (TyG) index variations on chronic kidney disease (CKD) progression remains unexplored. To investigate the effects of the TyG index and its dynamic changes on CKD progression. METHOD: This prospective cohort study included data from 8,418 hypertensive participants. The exposure variable in this study was defined as the difference between the TyG index at the last visit from that at baseline. The study's outcome variable was the progression of CKD, defined as follows: for subjects with an estimated glomerular filtration rate (eGFR) ≥60 mL/min, a ≥30% decrease in eGFR with a final follow-up value <60 mL/min; for those with an eGFR <60 mL/min, a ≥50% decrease in eGFR; or terminal renal failure requiring dialysis...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38405158/probiotic-co-supplementation-with-absorbent-smectite-for-pancreatic-beta-cell-function-in-type-2-diabetes-a-secondary-data-analysis-of-a-randomized-double-blind-controlled-trials
#20
JOURNAL ARTICLE
Maryana Savytska, Dmytro Kyriienko, Ganna Zaychenko, Danylo Ostapchenko, Tetyana Falalyeyeva, Nazarii Kobyliak
INTRODUCTION: There is growing evidence from animal and clinical studies suggesting probiotics can positively affect type 2 diabetes (T2D). In a previous randomized clinical study, we found that administering a live multistrain probiotic and absorbent smectite once a day for eight weeks to patients with T2D could reduce chronic systemic inflammatory state, insulin resistance, waist circumference and improve the glycemic profile. However, there is a lack of evidence supporting the efficacy of probiotic co-supplementation with absorbent smectite on pancreatic β-cell function in T2D...
2024: Frontiers in Endocrinology
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