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International Journal of Clinical Pharmacy

Rasmus Søgaard Nyholm, Jon Trærup Andersen, Charlotte Vermehren, Susanne Kaae
Background When women are in a condition that requires medicines during pregnancy they have to balance the health benefits of the medical treatment against the potential risk of harming their unborn child. Too high teratogenic risk perceptions among pregnant women can lead them to stop taking the medicine, worsening the symptoms for the mother and even harming their foetus. Many women today who use over-the-counter and prescribed medicines have been shown to change their medical behaviour when they become pregnant...
May 18, 2019: International Journal of Clinical Pharmacy
Danielle M van der Laan, Marlous Langendoen-Gort, Giel Nijpels, Christel C L M Boons, Petra J M Elders, Jacqueline G Hugtenburg
Background Insight into the delivery of interventions is necessary to gain a better understanding of what caused an intervention to succeed or fail. The Cardiovascular medication non-Adherence Tailored Intervention (CATI) study failed to show effectiveness of a patient-tailored, pharmacist-led intervention programme on self-reported adherence to antihypertensive medication. Objective To evaluate the implementation fidelity of the CATI intervention programme. Setting Twenty Dutch community pharmacies. Method The process of a randomised controlled trial was evaluated...
May 15, 2019: International Journal of Clinical Pharmacy
Lorenz Van der Linden, Liesbeth Decoutere, Leen Beerten, Toon Delva, Isabel Spriet, Johan Flamaing, Jos Tournoy
Background Clinical pharmacist interventions have been shown to improve drug use in older adults. Study findings are seldom externally validated however. Objective First, to validate a minimized iteration of a previously tested intervention of clinical pharmacists in a non-academic setting with limited staffing resources. Second, to compare the potentially inappropriate medication (PIM) reduction to two previous controlled interventional studies. Methods A controlled study was performed at geriatric wards. The control group received usual care...
May 15, 2019: International Journal of Clinical Pharmacy
Nikki L Damen, Bart J F Van den Bemt, Kurt E Hersberger, John Papastergiou, Filipa Alves da Costa, Silas Rydant, Naomi S Wartenberg, Trudy Lobban, Isabelle Arnet, Sotiris Antoniou
Background Oral anticoagulation therapy has proven beneficial impact on the prevention of thromboembolic events. However, the use of antocoagulatns also increases the risk of bleeds. To maximize the benefits and minimize the risks of the treatment, guidance on appropriate use of oral anticoagulants is essential. An international guideline describing relevant components and requirements for pharmaceutical care for patients receiving a therapy woth oral antocoagulants would increase the quality of care. However, recommendations on pharmaceutical care for patients on anticoagulation is lacking...
May 15, 2019: International Journal of Clinical Pharmacy
H Laetitia Hattingh, Michelle A King, Denise L Hope, Elizabeth George
Background Ethical reasoning informs decision making and professional judgement, is guided by codes of ethics and conduct, and requires navigation through a regulatory framework. Ethical reasoning should evolve throughout the pharmacy internship year and prepare interns for independent practice. Objective To explore the ethical reasoning and processes of Australian pharmacists and pharmacy interns. Setting Queensland community pharmacists and interns. Method A survey to determine use of resources to guide ethical decisions, management of ethical dilemmas, and exposure to potential practice privacy breaches...
May 15, 2019: International Journal of Clinical Pharmacy
Iwyson Henrique Fernandes da Costa, Renan Morais E Silva, Juliana de Oliveira Carlos, Maria Cleonice Araújo Silva, Maria Karine Cavalcante Pinheiro, Bruna Cristina Cardoso Martins, Paula Frassinetti Castelo Branco Camurça Fernandes, Marjorie Moreira Guedes
Background Older kidney transplant recipients take a larger number of medications than younger patients, but there is currently no evidence that this affects health outcomes or that is it associated with potentia medicine-related problems. Objective To evaluate the prevalence and number of potentially inappropriate medications in older kidney transplant recipients and also the possible associated factors (sex, age, comorbidities, number of medications, etc.). Setting A renal post-transplant ambulatory outpatient clinic of a university hospital in Fortaleza, Brazil...
May 15, 2019: International Journal of Clinical Pharmacy
Ngit Yi Liew, Ying Yee Chong, Shiau Huey Yeow, Kok Pim Kua, Pui San Saw, Shaun Wen Huey Lee
Background Polypharmacy has been associated with an increased risk of morbidity and mortality among older adults especially those living in nursing homes. Explicit criteria to evaluate the appropriateness of medications have recently been updated. Objective To estimate and compare the prevalence of potentially inappropriate medications (PIMs) among older adults in nursing homes using screening tool for older people's prescription (STOPP-2) and the 2015 Beers criteria. Setting Nursing care homes in the Klang Valley, Malaysia...
May 9, 2019: International Journal of Clinical Pharmacy
Michelle Yu Yin Lam, Linda J Dodds, Sarah A Corlett
Background The post-discharge Medicines-Use-Review (dMUR) is a commissioned service in England and Wales whereby community pharmacists facilitate patients' understanding of their medicines and resolve any medicine-related problems. This service is poorly utilised. Objective To explore the impact of raising hospital patients' awareness of dMURs on their uptake. Setting Hospital in South East England. Method Patients on medical wards with at least one change (medicine, or dose regimen) to their admission medicines were provided with standardized written and verbal information about the service...
May 9, 2019: International Journal of Clinical Pharmacy
Kannikar Semcharoen, Sajja Supornpun, Surakit Nathisuwan, Junporn Kongwatcharapong
Background Little information is available regarding pharmacist's intervention to solve drug-related problems (DRPs) in a stroke unit. Objective To investigate the nature and frequency of DRPs along with the role of pharmacists in a stroke unit. Setting The study was conducted at the stroke unit of Siriraj hospital, a university affiliated tertiary care hospital in Thailand. Method A retrospective descriptive study of DRPs and pharmacists' interventions for stroke patients was performed during July 2015 to December 2016...
May 3, 2019: International Journal of Clinical Pharmacy
Elien B Uitvlugt, Bart J F van den Bemt, Wai Lung Chung, Jaap Dik, Patricia M L A van den Bemt, Fatma Karapinar-Çarkit
Background In the Netherlands, a nationwide Medication Record System based on pharmacy dispensing data is used to obtain information about patients' actual medication use. However, it is not clear to what extent the information of the Nationwide Medication Record System corresponds to the medication information obtained with the Best Possible Medication History. Objective To examine the validity of medication dispensing records collected from the Nationwide Medication Record System by comparing them to the Best Possible Medication History...
April 27, 2019: International Journal of Clinical Pharmacy
María Ángeles Campos Fernández de Sevilla, Marta Gallego Úbeda, Miriam Heredia Benito, Emilio García-Cabrera, Beatriz Monje García, María Tovar Pozo, Laura Delgado Téllez de Cepeda, Irene Iglesias-Peinado
Background A pharmaceutical care program is necessary to improve the management of direct-acting antivirals in hepatitis C. Objective Describe health outcomes obtained with the implementation of a pharmaceutical care program in Hepatitis C patients treated with direct-acting antivirals. Setting This study was performed in a pharmacy department of a university hospital. Methods Retrospective study between 1st-April 2015 and 28st-February 2016. Hospital pharmacists implemented interventional measures for validation of antivirals prescriptions, detection of drug-interaction, adverse drug events, education and patient´s adherence to antiviral regimen...
April 27, 2019: International Journal of Clinical Pharmacy
Richelle C Kosse, Marcel L Bouvy, Tjalling W de Vries, Ellen S Koster
Background Several effective mobile health (mHealth) interventions have been developed to support patients with their medication use, however hardly any is implemented in clinical practice. Process evaluations and user experiences are therefore important for further implementation. Objective To explore experiences, barriers, and facilitators of pharmacists and patients towards the use of the interactive ADolescent Adherence Patient Tool (ADAPT). In addition, the perceptions of pharmacists towards mHealth interventions in general were explored...
April 27, 2019: International Journal of Clinical Pharmacy
Usama Asif, Ahsan Saleem, Imran Masood, Mehwish Nawaz
Background The model of community pharmacy practice is changing remarkably not only in the West but also in developing countries, which has led retail pharmacies to transform into chain community pharmacies. However, very little is known about consumers' expectations and experiences with chain community pharmacies in developing countries. Objective This study aims to assess the expectations and experiences of consumers with services provided by chain community pharmacies in Lahore, Pakistan. Setting Four random chain community pharmacies...
April 26, 2019: International Journal of Clinical Pharmacy
R Santolaya-Perrín, B Calderón-Hernanz, G Jiménez-Díaz, N Galán-Ramos, M T Moreno-Carvajal, J M Rodríguez-Camacho, P Serra-Simó, J C García-Ortiz, J Tarradas-Torras, A Ginés-Palomares, I Sánchez-Navarro
Background Older age and inappropriate prescribing is related to a greater rate of emergency department visits and hospitalisations. Objective To assess the efficacy of an interprofessional collaboration programme in which a review of the medication of older patients seen in the emergency observation unit was carried out. Setting Emergency departments at four Spanish hospitals. Method Randomised, controlled study. Patients over 65 years of age presenting to the emergency department were randomised to a control or an intervention group...
April 26, 2019: International Journal of Clinical Pharmacy
Ana Spasić, Aleksandra Catić-Đorđević, Radmila Veličković-Radovanović, Nikola Stefanović, Predrag Džodić, Tatjana Cvetković
Background Mycophenolic acid is widely used immunosuppressive drug, associated with adverse effects which increase patient morbidity and decrease medication adherence. Objective To evaluate the adverse effects in renal transplant recipients under mycophenolate treatment with respect to gender. Setting University Clinical Centre of Nis, Clinic of Nephrology, Serbia. Method This research included 96 renal transplant recipients, who received immunosuppressive regimen, based on tacrolimus or cyclosporin A, prednisone and mycophenolic acid...
April 26, 2019: International Journal of Clinical Pharmacy
Mike Wilcock, Alison Hill, Amber Wynn, Liam Kelly
Background The poor quality of discharge summaries following admission to hospital, especially in relation to information on medication changes, is well documented. Hospital pharmacists can record changes to medications in the electronic discharge note to improve the quality of this information for primary care. Objective To audit the pharmacist-completed notes describing changes to admission medication, and to identify improvement opportunities. Setting 750-bed teaching district general hospital in England...
April 26, 2019: International Journal of Clinical Pharmacy
Karin Svensberg, Hedvig Nordeng, Sahar Gaffari, Kate Faasse, Rob Horne, Angela Lupattelli
Background Little is known about patients' Perceived Sensitivity to Medicines (PSM), "the belief that one is especially sensitive to the actions and side effects of medicines". Objective (i) To explore the extent of and factors associated with high Perceived Sensitivity to Medicines in a Norwegian population of chronic medicine users; (ii) to assess the psychometric characteristics of the tool to measure PSM. Setting Community pharmacies in the Oslo area, Norway. Method A cross-sectional, questionnaire-based study was conducted between October 2015 and January 2016...
April 26, 2019: International Journal of Clinical Pharmacy
Marta Lavrador, Alice A Silva, Ana C Cabral, M Margarida Caramona, Fernando Fernandez-Llimos, Isabel V Figueiredo, M Margarida Castel-Branco
BACKGROUND: Beers Criteria are one of the best known explicit criteria to identify inappropriate medication in elderly that can be used in medication review. The access to patients' medical records may be different among healthcare professionals and settings and, subsequently, the identification of patients' diagnoses may be compromised. OBJECTIVE: To assess the consequences of ignoring patient diagnoses when applying 2015 Beers Criteria to identify potentially inappropriate medication (PIM)...
April 24, 2019: International Journal of Clinical Pharmacy
Ellen S Koster, Daphne Philbert, Kay R Wagelaar, Sarah Galle, Marcel L Bouvy
Background Atopic dermatitis affects 10-20% of the children worldwide. Unfortunately not all patients who receive treatment have optimal treatment outcomes. Objective To assess the view of parents and pharmacy staff in order to optimize pharmaceutical care for young atopic dermatitis patients. Setting Community pharmacies in the Netherlands. Method We first held an expert panel meeting to determine experts' views on treatment of atopic dermatitis and their suggestions for areas of improvement. This input was used to develop the interview guide...
April 24, 2019: International Journal of Clinical Pharmacy
Kok Pim Kua, Pui San Saw, Shaun Wen Huey Lee
Background Deprescribing describes a process of medication regimen optimization with the aim to reduce adverse events and improve quality of life. There is limited research on perceptions of older adults, defined as those 60 years of age and older, about their willingness to cease a medication in developing countries. Objective To ascertain patients' attitudes, beliefs, perceptions, and experiences regarding the number of medications they were taking and their opinions regarding deprescribing. Setting A primary care health clinic and three community pharmacies in Malaysia...
April 24, 2019: International Journal of Clinical Pharmacy
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