journal
https://read.qxmd.com/read/38760036/do-studies-evaluating-early-life-policy-interventions-fully-adhere-to-the-critical-conditions-of-difference-in-differences-a-systematic-review
#21
JOURNAL ARTICLE
Anouk Klootwijk, Jeroen Struijs, Annelieke Petrus, Marlin Leemhuis, Mattijs Numans, Eline de Vries
OBJECTIVES: To assess the reporting and methodological quality of early-life policy intervention papers that applied difference-in-differences (DiD) analysis. STUDY DESIGN: Systematic review. DATA SOURCES: Papers applying DiD of early-life policy interventions in high-income countries as identified by searching Medline, Embase and Scopus databases up to December, 2022. STUDY ELIGIBILITY CRITERIA, PARTICIPANTS AND INTERVENTIONS: Studies evaluating policy interventions targeting expectant mothers, infants or children up to two years old and conducted in high income countries were included...
May 16, 2024: BMJ Open
https://read.qxmd.com/read/38760034/investigating-consumer-preferences-and-experiences-of-telehealth-services-in-australian-allied-health-practice-a-study-protocol
#22
JOURNAL ARTICLE
Madison Frith, James Boyd, Feby Savira, Deniz Senyel, Richard Norman, Janelle Jones, Suzanne Robinson
INTRODUCTION: Telehealth service provision and uptake has rapidly increased since the COVID-19 pandemic, allowing healthcare to be delivered safely and reducing non-essential face-to-face (F2F) contact. In Australia, the expansion of subsidisation of telehealth during COVID has led to its permanent installation within Australian primary care in 2022. However, little is known about consumer preferences and experiences with these services, particularly in relation to allied health practice (AHP)...
May 16, 2024: BMJ Open
https://read.qxmd.com/read/38760033/effect-of-metformin-use-on-graft-and-patient-survival-in-kidney-transplant-recipients-with-type-2-diabetes-a-systematic-review-protocol
#23
JOURNAL ARTICLE
Farooq Shamshad, Somkanya Tungsanga, Peter Senior, Soroush Shojai, Anukul Ghimire, Feng Ye, Janice Y Kung, Vinash K Hariramani, Abdullah Abdulrahman, Matthew Penney, Naima Sultana, Shezel Muneer, Ikechi Okpechi, Aminu K Bello
INTRODUCTION: Metformin is a first-line antihyperglycaemic agent for type 2 diabetes (T2DM). In addition to glycaemic control, it offers benefits related to cardiovascular health, weight neutrality and metabolic syndrome. However, its benefits in kidney transplant recipients remain unclear as metformin use is controversial in this population due to a lack of evidence and there are recommendations against its use in patients with poor kidney function. Hence, we seek to describe a protocol for a systematic review, which will assess the impact of metformin use on graft survival and mortality in kidney transplant recipients...
May 16, 2024: BMJ Open
https://read.qxmd.com/read/38760032/explorative-observational-study-of-dutch-patient-clinician-interactions-operationalisation-of-personal-perspective-elicitation-as-part-of-shared-decision-making-in-real-life-audio-recorded-consultations
#24
JOURNAL ARTICLE
Ester A Rake, Marjan J Meinders, Guus Brand, Dunja Dreesens, Jan A M Kremer, Glyn Elwyn, Johanna W M Aarts
OBJECTIVES: Patients' preferences, values and contexts are important elements of the shared decision-making (SDM) process. We captured those elements into the concept of 'personal perspective elicitation' (PPE), which reflects the need to elicit patients' preferences, values and contexts in patient-clinician conversations. We defined PPE as: 'the disclosure (either elicited by the clinician or spontaneously expressed by the patient) of information related to the patient's personal preferences, values and/or contexts potentially relevant to decision-making'...
May 16, 2024: BMJ Open
https://read.qxmd.com/read/38760031/an-observational-study-protocol-to-capture-validate-and-characterise-lucid-episodes-in-people-living-with-advanced-dementia-receiving-hospice-care
#25
JOURNAL ARTICLE
Andrea Gilmore-Bykovskyi, Kayla Dillon, Alison Coulson, Jess Fehland, Clark Benson, Leah Sanson-Miles, Kimberly Mueller
INTRODUCTION: Lucid episodes (LEs) in advanced neurodegenerative disease, characterised by a transient recovery of abilities, have been reported across neurological conditions, including Alzheimer's disease and related dementias. Evidence on LEs in dementia is extremely limited and draws predominantly from retrospective case reports. Lucidity in dementia has received growing attention given the clinical, caregiving and potential epidemiological implications of even a temporary return of abilities in advanced disease...
May 16, 2024: BMJ Open
https://read.qxmd.com/read/38760030/what-is-current-care-for-people-with-long-covid-in-england-a-qualitative-interview-study
#26
JOURNAL ARTICLE
David Sunkersing, Mel Ramasawmy, Nisreen A Alwan, Donna Clutterbuck, Yi Mu, Kim Horstmanshof, Amitava Banerjee, Melissa Heightman
OBJECTIVE: To investigate current care for people with Long COVID in England. DESIGN: In-depth, semistructured interviews with people living with Long COVID and Long COVID healthcare professionals; data analysed using thematic analysis. SETTING: National Health Service England post-COVID-19 services in six clinics from November 2022 to July 2023. PARTICIPANTS: 15 healthcare professionals and 21 people living with Long COVID currently attending or discharged (18 female; 3 male)...
May 16, 2024: BMJ Open
https://read.qxmd.com/read/38760029/strategies-to-address-recruitment-to-a-randomised-trial-of-surgical-and-non-surgical-treatment-for-cancer-results-from-a-complex-recruitment-intervention-within-the-mesothelioma-and-radical-surgery-2-mars-2-study
#27
RANDOMIZED CONTROLLED TRIAL
Nicola Mills, Nicola Farrar, Barbara Warnes, Kate E Ashton, Rosie Harris, Chris A Rogers, Eric Lim, Daisy Elliott
OBJECTIVES: Recruiting to randomised trials is often challenging particularly when the intervention arms are markedly different. The Mesothelioma and Radical Surgery 2 randomised controlled trial (RCT) compared standard chemotherapy with or without (extended) pleurectomy decortication surgery for malignant pleural mesothelioma. Anticipating recruitment difficulties, a QuinteT Recruitment Intervention was embedded in the main trial phase to unearth and address barriers. The trial achieved recruitment to target with a 4-month COVID-19 pandemic-related extension...
May 16, 2024: BMJ Open
https://read.qxmd.com/read/38760028/effectiveness-of-combining-prevention-psychological-interventions-with-interventions-that-address-the-social-determinants-of-mental-health-in-low-and-middle-income-countries-protocol-of-a-systematic-review-and-meta-analysis
#28
JOURNAL ARTICLE
Eleonora Prina, Beatrice Bano, Rakesh Singh, Emiliano Albanese, Daniela Trujillo, María Cecilia Dedios Sanguineti, Katherine Sorsdahl, Nagendra P Luitel, Emily C Garman, Marianna Purgato, Corrado Barbui, Mark J D Jordans, Crick Lund
INTRODUCTION: Common mental health conditions (CMHCs), including depression, anxiety and post-traumatic stress disorder (PTSD), are highly prevalent in low and middle-income countries (LMICs). Preventive strategies combining psychological interventions with interventions addressing the social determinants of mental health may represent a key strategy for effectively preventing CMHCs. However, no systematic reviews have evaluated the effectiveness of these combined intervention strategies for preventing CMHCs...
May 16, 2024: BMJ Open
https://read.qxmd.com/read/38754891/preoperative-walking-exercise-to-improve-prognosis-in-patients-with-supratentorial-brain-tumours-after-craniotomy-protocol-for-a-randomised-controlled-trial
#29
JOURNAL ARTICLE
Chunrun Qu, Zeng Cao, Jun Zhou, Shihan He, Fangkun Liu, Zhixiong Liu
INTRODUCTION: Cardiopulmonary complications and cognitive impairment following craniotomy have a significantly impact on the general health of individuals with brain tumours. Observational research indicates that engaging in walking is linked to better prognosis in patient after surgery. This trial aims to explore whether walking exercise prior to craniotomy in brain tumour patients can reduce the incidence of cardiopulmonary complications and preserve patients' cognitive function. METHODS AND ANALYSIS: In this randomised controlled trial, 160 participants with supratentorial brain tumours aged 18-65 years, with a preoperative waiting time of more than 3-4 weeks and without conditions that would interfere with the trial such as cognitive impairment, will be randomly assigned in a ratio of 1:1 to either receive traditional treatment or additional combined with a period of 3-4 weeks of walking exercise of 10 000-15 000 steps per day...
May 15, 2024: BMJ Open
https://read.qxmd.com/read/38754890/physicians-emotion-awareness-and-emotion-regulation-training-during-medical-education-a-systematic-scoping-review-protocol
#30
JOURNAL ARTICLE
Anna Adelheid Lange, Raphaël Bonvin, Sissel Guttormsen, Sofia Carolina Zambrano Ramos
INTRODUCTION: The objective of this systematic scoping review is to identify what approaches have been implemented in medical education programmes to teach medical students the skills to identify and manage emotions that may be elicited in them during physician-patient interactions and in the clinical environment. Emotions of all involved in the clinical encounter are central to the process of clinical care. However, a gap remains addressing and teaching medical students about recognising and dealing with their own emotions...
May 15, 2024: BMJ Open
https://read.qxmd.com/read/38754889/factors-influencing-smartwatch-use-and-comfort-with-health-data-sharing-a-sequential-mixed-method-study-protocol
#31
JOURNAL ARTICLE
Anthony James Goodings, Kayode Philip Fadahunsi, Derjung Mimi Tarn, Patrick Henn, Frances Shiely, John O'Donoghue
INTRODUCTION: Smartwatches have become ubiquitous for tracking health metrics. These data sets hold substantial potential for enhancing healthcare and public health initiatives; it may be used to track chronic health conditions, detect previously undiagnosed health conditions and better understand public health trends. By first understanding the factors influencing one's continuous use of the device, it will be advantageous to assess factors that may influence a person's willingness to share their individual data sets...
May 15, 2024: BMJ Open
https://read.qxmd.com/read/38754888/performance-of-glial-fibrillary-acidic-protein-gfap-and-ubiquitin-carboxy-terminal-hydrolase-l1-uch-l1-biomarkers-in-predicting-ct-scan-results-and-neurological-outcomes-in-children-with-traumatic-brain-injury-braini-2-paediatric-study-protocol-of-a-european
#32
MULTICENTER STUDY
Fleur Lorton, Alfonso Lagares, Javier de la Cruz, Odile Méjan, Vladislav Pavlov, Vincent Sapin, Maria Antonia Poca, Markus Lehner, Peter Biberthaler, Anne Chauviré-Drouard, Christèle Gras-Le-Guen, Pauline Scherdel
INTRODUCTION: In light of the burden of traumatic brain injury (TBI) in children and the excessive number of unnecessary CT scans still being performed, new strategies are needed to limit their use while minimising the risk of delayed diagnosis of intracranial lesions (ICLs). Identifying children at higher risk of poor outcomes would enable them to be better monitored. The use of the blood-based brain biomarkers glial fibrillar acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase-L1 (UCH-L1) could help clinicians in this decision...
May 15, 2024: BMJ Open
https://read.qxmd.com/read/38754887/restore-and-rebuild-r-r-a-protocol-for-a-phase-2-randomised-control-trial-to-compare-r-r-as-a-treatment-for-moral-injury-related-mental-health-difficulties-in-uk-military-veterans-to-treatment-as-usual
#33
RANDOMIZED CONTROLLED TRIAL
Victoria Williamson, Dominic Murphy, Amanda Bonson, Natasha Biscoe, Daniel Leightley, Vicky Aldridge, N Greenberg
BACKGROUND: Exposure to potentially morally injurious events is increasingly recognised as a concern across a range of occupational groups, including UK military veterans. Moral injury-related mental health difficulties can be challenging for clinicians to treat and there is currently no validated treatment available for UK veterans. We developed Restore and Rebuild (R&R) as a treatment for UK veterans struggling with moral injury-related mental health difficulties. This trial aims to examine whether it is feasible to conduct a pilot randomised controlled trial (RCT) of R&R treatment compared with a treatment-as-usual (TAU) control group...
May 15, 2024: BMJ Open
https://read.qxmd.com/read/38754886/research-priorities-for-the-management-of-major-trauma-an-international-priority-setting-partnership-with-the-james-lind-alliance
#34
JOURNAL ARTICLE
Christopher Patrick Bretherton, Robert Hirst, Hamez Gacaferi, Jonathan Gower, Lauren Exell, Scott Johnston, Shan Martin, Caroline Leech, Catherine Hilton, Ceri Battle, Daniel Axelrod, Heather Vallier, Daphne Van Embden, David J Stockton, Elaine Cole, Julia Williams, Louise Johnson, Maritz Laubscher, Melissa Webb, Philip Braude, Sarah Norris, Steve Bell, Sithombo Maqungo, Xavier Luke Griffin
OBJECTIVE: The objective of this study is to determine research priorities for the management of major trauma, representing the shared priorities of patients, their families, carers and healthcare professionals. DESIGN/SETTING: An international research priority-setting partnership. PARTICIPANTS: People who have experienced major trauma, their carers and relatives, and healthcare professionals involved in treating patients after major trauma...
May 15, 2024: BMJ Open
https://read.qxmd.com/read/38754885/nurses-and-midwives-experiences-of-clinical-supervision-in-practice-a-scoping-review-protocol
#35
REVIEW
Nicola Gill-Meeley, Siobhan Smyth, Timothy Frawley, Ciaran Cuddihy, Orlaith Hernon
OBJECTIVE: To outline and examine what evidence exists related to nurses' and midwives' experiences of participating in clinical supervision. INTRODUCTION: The practice of clinical supervision is increasingly prevalent in nursing and midwifery, yet disparity remains in relation to professionals' understanding and experience of this clinical support and how it is implemented in practice. This scoping review will identify the available evidence and gaps in knowledge that exist in relation to nurses' and midwives' experience of this practice and examine how the various forms are defined in the literature...
May 15, 2024: BMJ Open
https://read.qxmd.com/read/38754884/risk-adjusted-trend-in-national-inpatient-fall-rates-observed-from-2011-to-2019-in-acute-care-hospitals-in-switzerland-a-repeated-multicentre-cross-sectional-study
#36
MULTICENTER STUDY
Niklaus S Bernet, Irma H J Everink, Sabine Hahn, Marianne Müller, Jos M G A Schols
OBJECTIVES: This study aimed to investigate whether a significant trend regarding inpatient falls in Swiss acute care hospitals between 2011 and 2019 could be confirmed on a national level, and whether the trend persists after risk adjustment for patient-related fall risk factors. DESIGN: A secondary data analysis was conducted based on annual multicentre cross-sectional studies carried out between 2011 and 2019. SETTING: All Swiss acute care hospitals were obliged to participate in the surveys...
May 15, 2024: BMJ Open
https://read.qxmd.com/read/38754883/mentalising-imagery-therapy-for-family-dementia-caregivers-protocol-for-a-scoping-review
#37
JOURNAL ARTICLE
Xue Jiang, Hu Jiang
INTRODUCTION: Dementia is a growing public health concern, and providing long-term care for individuals affected by this condition is challenging for their family caregivers. While researchers have explored various intervention options to provide psychological support for dementia caregivers, mentalising imagery therapy (MIT) has gained significant recognition as an effective programme. Despite its significance and effectiveness, there is a lack of comprehensive scoping reviews of MIT in dementia caregiving...
May 15, 2024: BMJ Open
https://read.qxmd.com/read/38754882/social-support-in-maintaining-mental-health-and-quality-of-life-among-community-dwelling-older-people-with-functional-limitations-in-malaysia-a-population-based-cross-sectional-study
#38
JOURNAL ARTICLE
Nur Zahirah Balqis-Ali, Weng Hong Fun
OBJECTIVE: This study aimed to examine the mediation role of perceived social support in the relationship between functional limitations, depressive symptoms and quality of life among older people in Malaysia. SETTING: The Malaysian National Health Morbidity Survey 2018: Elderly Health was a cross-sectional health community survey among adults aged 50 and above. PARTICIPANTS: 3977 community-dwelling older Malaysians aged 60 and above. OUTCOME MEASURES: Functional limitations were defined as personal activities of daily living (PADL) and instrumental activities of daily living (IADL), tested in separate paths in all analyses...
May 15, 2024: BMJ Open
https://read.qxmd.com/read/38754881/novel-biomarker-profiles-to-improve-individual-diagnosis-and-prognosis-in-patients-with-suspected-inflammatory-bowel-disease-protocol-for-the-nordic-inception-cohort-study-nordtreat
#39
JOURNAL ARTICLE
Anja Fejrskov, Johannes David Füchtbauer, Lóa G Davíðsdóttir, Jonas Halfvarson, Marte Lie Høivik, Michael Dam Jensen, Joachim Høg Mortensen, Lene Nyholm Nielsen, Martin Rejler, Dirk Repsilber, Johan D Söderholm, Claus Aalykke, Vibeke Andersen, Robin Christensen, Jens Kjeldsen
INTRODUCTION: Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, can be challenging to diagnose, and treatment outcomes are difficult to predict. In the NORDTREAT cohort study, a Nordic prospective multicentre study, we aim to identify novel molecular biomarkers of diagnostic value by assessing the diagnostic test accuracy (cross-sectionally), as well as the prognostic utility when used as prognostic markers in the long-term (cohort study). In the diagnostic test accuracy study, the primary outcome is a successful diagnosis using one or more novel index tests at baseline compared with the ECCO criteria as the reference standard...
May 15, 2024: BMJ Open
https://read.qxmd.com/read/38754880/comparison-of-three-diagnostic-strategies-for-suspicion-of-pulmonary-embolism-planar-ventilation-perfusion-scan-v-q-ct-pulmonary-angiography-ctpa-and-single-photon-emission-ct-ventilation-perfusion-scan-spect-v-q-a-protocol-of-a-randomised-controlled-trial
#40
RANDOMIZED CONTROLLED TRIAL
Romain Le Pennec, Pierre-Yves Le Roux, Philippe Robin, Francis Couturaud, Marc Righini, Grégoire Le Gal, Pierre-Yves Salaun
INTRODUCTION: Pulmonary embolism (PE) is a challenge to diagnose and when missed, exposes patients to potentially fatal recurrent events. Beyond CT pulmonary angiography (CTPA) and planar ventilation/perfusion (V/Q) scan, single photon emission CT (SPECT) V/Q emerged a new diagnostic modality of scintigraphic acquisition that has been reported to improve diagnostic performances. To date, no management outcome study or randomised trial evaluated an algorithm based on SPECT V/Q for PE diagnosis...
May 15, 2024: BMJ Open
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