journal
https://read.qxmd.com/read/37163174/safe-blood-donation-from-donors-using-antihypertensive-medication-a-multi-center-retrospective-quality-study-from-south-east-norway
#1
JOURNAL ARTICLE
Kathrine M Neuman Johnsen, Karin Magnussen, Christian Erstad, Sadaf Nabi Bhatti, Lise Sofie H Nissen-Meyer
PURPOSE: In Norway, blood donors using antihypertensive medication were deferred until 2015. Following revision of the national directive, these donors could be allowed, providing stable dose for at least 3 months, adequate blood pressure control and no adverse effects caused by the therapy. The new practice was evaluated by a quality study where the major aim was to establish whether donations from blood donors on antihypertensive medication pose a risk to the donor. The risk was assessed by counting the number and categorizing the adverse events related to blood donation...
2023: Journal of Blood Medicine
https://read.qxmd.com/read/37123985/rnai-for-the-treatment-of-people-with-hemophilia-current-evidence-and-patient-selection
#2
REVIEW
Sara Boyce, Savita Rangarajan
Severe hemophilia is associated with spontaneous, prolonged and recurrent bleeding. Inadequate prevention and treatment of bleeding can lead to serious morbidity and mortality. Due to the limitations of intravenous clotting factor replacement, including the risk of inhibitory antibodies, innovative novel therapies have been developed that have dramatically changed the landscape of hemophilia therapy. Ribonucleic acid interference (RNAi) has brought the opportunity for multiple strategies to manipulate the hemostatic system and ameliorate the bleeding phenotype in severe bleeding disorders...
2023: Journal of Blood Medicine
https://read.qxmd.com/read/37123984/-severe-anemia-a-case-report-of-an-uncommon-precipitant-of-schizophrenia-relapse
#3
Krittisak Anuroj, Siwat Chongbanyatcharoen, Romteera Chiencharoenthanakij
A 48-year-old patient with stable residual schizophrenia experienced a syndromic psychosis relapse following an episode of severe combined immunohemolytic and pure red cell aplastic anemia, with a hemoglobin level of 4.7 g/dl. The anemia was attributed to her anti-HIV medication zidovudine. Her HIV infection had been well-controlled; no other organic precipitant of the psychosis was found. Following transfusion of 2 units of leukocyte-poor packed red cells, schizophrenia symptoms promptly recovered to her baseline...
2023: Journal of Blood Medicine
https://read.qxmd.com/read/37089826/d-dimer-level-associated-with-amount-of-sinus-involvement-using-digital-subtraction-angiography-on-cerebral-venous-thrombosis-patients
#4
JOURNAL ARTICLE
Lisda Amalia
BACKGROUND: Cerebral venous sinus thrombosis (CVST) is a form of the cerebrovascular disease characterized by varying degrees of obstruction of veins and cerebral sinuses caused by thrombus. Diagnosis is incredibly challenging due to the wide variety of symptoms and the distinct radiological aspects of affected vessels. In patients with venous thrombosis, the presence of D-Dimer is used as an indicator of the presence of endogenous fibrinolysis. D-Dimer is a by-product of fibrin polymer fragmentation...
2023: Journal of Blood Medicine
https://read.qxmd.com/read/37089825/military-blood-service-in-poland
#5
JOURNAL ARTICLE
Tomasz Kryczka, Anna Jedynak, Adam Olszewski, Lidia Sierpinska, Paula Kuzniarska, Dorota Sulejczak
INTRODUCTION: On 24 February 2022, the Russia-Ukraine military conflict unfolded just across the eastern border of the European Union. It made everyone realize how important it is to secure blood supplies to health-care units in the event of an armed conflict. This paper presents the principles of functioning of the Military Blood Donation Service and the Military Center for Blood Donation and Hemotherapy in Poland. METHODS: The study used data collected in the "Military Blood Bank" information processing system and data from annual reports (2010-2021) sent to the Minister of Health of the Republic of Poland...
2023: Journal of Blood Medicine
https://read.qxmd.com/read/37082003/managing-the-cerebrovascular-complications-of-sickle-cell-disease-current-perspectives
#6
REVIEW
Jennifer Light, Maria Boucher, Jacquelyn Baskin-Miller, Mike Winstead
The importance of protecting brain function for people with sickle cell disease (SCD) cannot be overstated. SCD is associated with multiple cerebrovascular complications that threaten neurocognitive function and life. Without screening and preventive management, 11% of children at 24% of adults with SCD have ischemic or hemorrhagic strokes. Stroke screening in children with SCD is well-established using transcranial Doppler ultrasound (TCD). TCD velocities above 200 cm/s significantly increase the risk of stroke, which can be prevented using chronic red blood cell (RBC) transfusion...
2023: Journal of Blood Medicine
https://read.qxmd.com/read/37082002/immune-thrombocytopenia-relapse-in-patients-who-received-mrna-covid-19-vaccines
#7
JOURNAL ARTICLE
Hana Qasim, Alaa Rahhal, Ahmed Husain, Abdelkarim Alammora, Khaled Alsa'ed, Ahmed Abdelghafar Masaad Alsayed, Baha Faiyoumi, Leen Maen AbuAfifeh, Mohammad Abu-Tineh, Awni Alshurafa, Mohamed A Yassin
BACKGROUND: Immune thrombocytopenia (ITP) is a blood disorder in which antibodies coating platelets cause platelet destruction in the spleen with a resultant low platelet count and an increased tendency for bleeding. Coronavirus disease 2019 (COVID-19) is an illness caused by SARS-CoV-2. Though pneumonia and respiratory failure are major causes of morbidity and mortality, multisystemic complications were identified, including hematological ones. Several ITP relapse cases post-mRNA SARS-CoV-2 vaccines have been reported, and different pathophysiological theories have been proposed...
2023: Journal of Blood Medicine
https://read.qxmd.com/read/37051025/chronic-myeloid-leukemia-from-pathophysiology-to-treatment-free-remission-a-narrative-literature-review
#8
REVIEW
Ikhwan Rinaldi, Kevin Winston
Chronic myeloid leukemia (CML) is one of the most common leukemias occurring in the adult population. The course of CML is divided into three phases: the chronic phase, the acceleration phase, and the blast phase. Pathophysiology of CML revolves around Philadelphia chromosome that constitutively activate tyrosine kinase through BCR-ABL1 oncoprotein. In the era of tyrosine kinase inhibitors (TKIs), CML patients now have a similar life expectancy to people without CML, and it is now very rare for CML patients to progress to the blast phase...
2023: Journal of Blood Medicine
https://read.qxmd.com/read/37041968/prevalence-of-inherited-thrombophilia-in-women-with-recurrent-pregnancy-loss-during-the-first-trimester-of-pregnancy
#9
JOURNAL ARTICLE
Tagwa Yousif Elsayed Yousif
PURPOSE: This study aims to investigate the prevalence of inherited thrombophilia in women with recurrent pregnancy loss during the first trimester of pregnancy. The study was assessed the potential role of inherited thrombophilia in recurrent miscarriages and evaluate the consequences of this condition on the reproductive outcomes of affected women. MATERIAL AND METHODS: This study was an analytical descriptive carried out in Khartoum, Sudan. The research comprised 98 controls who had given birth twice or more without experiencing a miscarriage and 120 patients...
2023: Journal of Blood Medicine
https://read.qxmd.com/read/37025988/congenital-methemoglobinemia-first-confirmed-case-in-the-arab-population-with-a-novel-variant-in-the-cyb5r-gene-in-the-state-of-qatar-a-case-report
#10
Abdulrahman Al-Abdulmalek, Reem Al-Sulaiman, Mohammad Abu-Tineh, Mohamed A Yassin
Methemoglobinemia (MetHb) is a rare hematological condition characterized by high methemoglobin levels in the blood. It happens when hemoglobin is oxidized, resulting in hypoxia and cyanosis, which may occur in inherited or acquired forms. Inherited or congenital methemoglobinemia is a rare autosomal recessive condition and has never been reported in the Arab population. Here we report a case of a 22-year-old Arab man with a positive family history who presented with bluish discoloration of the fingers and lips and was found to have methemoglobinemia...
2023: Journal of Blood Medicine
https://read.qxmd.com/read/37016662/howell-jolly-body-like-inclusions-in-coronavirus-disease-2019-covid-19-possible-novel-findings
#11
JOURNAL ARTICLE
Amaylia Oehadian, Ian Huang, Andini Kartikasari, Bachti Alisjahbana, Delita Prihatni
BACKGROUND: During COVID-19 pandemic, it is difficult to distinguish febrile patient infected by SARS-CoV-2 or bacterial causes. Howell-Jolly bodies are a well-known entity found in red blood cells. They are nuclear fragments, composed of deoxyribonucleic acid, commonly observed in the peripheral blood smears of hyposplenic or asplenic patients. Recently, similar inclusions often referred to as Howell-Jolly body-like inclusions (HJBLIs) have been reported in the neutrophils of patients with acquired immune deficiency syndrome (AIDS) and COVID-19 patient...
2023: Journal of Blood Medicine
https://read.qxmd.com/read/37016661/pegcetacoplan-a-new-opportunity-for-complement-inhibition-in-pnh
#12
REVIEW
Ilene Ceil Weitz
Pegcetacoplan is the newest inhibitor of the complement system to be approved by the FDA and EMA for the treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH). The cyclic peptide inhibitor of C3 was evaluated in several clinical trials in PHN leading to its approval. The focus of this paper will review the efficacy and safety of Pegcetacoplan (PEG), and considerations for use in patients with PNH.
2023: Journal of Blood Medicine
https://read.qxmd.com/read/37009130/critical-assessment-of-transfusional-practices-in-the-obstetrics-and-gynecology-department-at-the-university-hospital-of-kinshasa
#13
JOURNAL ARTICLE
Yvon Wangi Ngoy, Mireille Solange Nganga Nkanga, Guy Ndelembo Baina, Audrey Katende Katende, Jacques Bikaula Ngwidiwo, Lethy Mpudi Massamba, Fanny Walo Diessa, Bienvenu Kuyangisa Boloko, Héritier Mawalala Malengele, Benjamin Longo-Mbenza
INTRODUCTION: Gynecology and obstetrics are among the specialties where blood transfusion is most practiced. This situation requires the use of good transfusion practices. The objective of this study was to assess the quality of transfusion practice in the Gynecology and Obstetrics Department of the University Hospital of Kinshasa (UHK). METHODS: This is a prospective, evaluative and descriptive study performed at the Department of Gyneco-Obstetrics of the University Hospital of Kinshasa from February 25 to June 25, 2020; which dealt with patients who received at least one blood transfusion...
2023: Journal of Blood Medicine
https://read.qxmd.com/read/36998244/validation-of-the-international-consensus-group-criteria-for-slide-review-following-automated-complete-blood-count-at-jimma-medical-center-ethiopia
#14
JOURNAL ARTICLE
Girum Tesfaye Kiya, Aklilu Getachew Mamo, Sintayehu Asaye Biya, Dejene Gebre Gobena, Natal Demeke, Tilahun Yemane Shenkutie
BACKGROUND: The international consensus group suggested criteria for action following automated complete blood count and white blood cell differential analysis. These criteria were set based on data from laboratories of developed countries. It is highly important to validate the criteria in developing countries where infectious diseases are still rampant that can affect blood cell count and morphology. Thus, this study aimed to validate the consensus group criteria for slide review at Jimma Medical Center, Ethiopia from November 1, 2020 to February 30, 2021...
2023: Journal of Blood Medicine
https://read.qxmd.com/read/36891167/prolonged-exposure-to-caplacizumab-as-rescue-therapy-in-refractory-immune-thrombotic-thrombocytopenic-purpura
#15
George M Rodgers, Misa Berndt, Megan Fonteno, Jeffrey A Gilreath
We describe a case of refractory thrombotic thrombocytopenic purpura (7 lines of therapy) in which caplacizumab was used over a 6-month period as rescue therapy. Caplacizumab maintained the patient in clinical remission until successful immunosuppression was achieved resulting in normal ADAMTS13 levels. This case illustrates the utility of caplacizumab therapy in treating refractory TTP.
2023: Journal of Blood Medicine
https://read.qxmd.com/read/36891166/von-willebrand-disease-epidemiology-burden-of-illness-and-management-a-systematic-review
#16
REVIEW
Ping Du, Aurore Bergamasco, Yola Moride, Françoise Truong Berthoz, Gülden Özen, Spiros Tzivelekis
INTRODUCTION: Although hereditary von Willebrand disease (VWD) is the most common bleeding disorder, its epidemiology is not well understood. A systematic review (PROSPERO CRD42020197674/CRD42021244374) on the epidemiology/burden of illness of VWD was conducted to better understand patients' unmet needs. METHODS: Observational studies (published January 1, 2010 to April 14, 2021) were identified in MEDLINE and Embase databases, using free-text keywords and thesaurus terms for VWD and outcomes of interest...
2023: Journal of Blood Medicine
https://read.qxmd.com/read/36855559/effectiveness-of-covid-19-convalescent-plasma-ccp-during-the-pandemic-era-a-literature-review
#17
REVIEW
Usha Rani Kandula, Techane Sisay Tuji, Dinkinesh Begna Gudeta, Kassech Leta Bulbula, Anwar Abdulwahed Mohammad, Ketema Diriba Wari, Ahmad Abbas
Worldwide pandemic with coronavirus disease-2019 (COVID-19) was caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). As November 2, 2022, World Health Organization (WHO) received 628,035,553 reported incidents on COVID-19, with 6,572,800 mortalities and, with a total 12,850,970,971 vaccine doses have been delivered as of October 31, 2022. The infection can cause mild or self-limiting symptoms of pulmonary and severe infections or death may be caused by SARS-CoV-2 infection. Simultaneously, antivirals, corticosteroids, immunological treatments, antibiotics, and anticoagulants have been proposed as potential medicines to cure COVID-19 affected patients...
2023: Journal of Blood Medicine
https://read.qxmd.com/read/36846350/outcome-of-primary-mediastinal-large-b-cell-lymphoma-treated-with-rchop
#18
JOURNAL ARTICLE
Khalid Halahleh, Abeer Yaseen, Isra Muradi, Akram Al-Ibraheem, Iyad Sultan, Mohammad Ma'koseh
PURPOSE: Primary mediastinal large B-cell Lymphoma (PMLBCL) is a rare aggressive lymphoma with unique clinical, pathological, and molecular features. The optimal frontline therapy is subject of ongoing debate. Our study aims to evaluate the outcomes of PMLBCL treated with rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (RCHOP) at King Hussein Cancer Center. PATIENTS AND METHODS: Adult patients >18 years of age with PMLBCL treated with RCHOP from January 2011 to July 2020 were identified...
2023: Journal of Blood Medicine
https://read.qxmd.com/read/36846349/optimizing-haemophilia-care-in-resource-limited-countries-current-challenges-and-future-prospects
#19
REVIEW
Annick Ndoumba-Mintya, Yacouba L Diallo, Tagny C Tayou, Dora N Mbanya
About 75% of persons with hemophilia live in the developing world and do not have access to routine care due to many barriers. There are a lot of challenges associated with hemophilia care in resource-limited settings, ranging from financial to organisational and government commitments. This review discusses some of these challenges and future prospects, while highlighting the important role of the World Federation of Hemophilia in hemophilia patient care. A participative approach involving all stakeholders is key to optimizing care in resource-limited settings...
2023: Journal of Blood Medicine
https://read.qxmd.com/read/36825218/genotyping-approach-to-predict-co-a-and-co-b-antigens-in-thai-blood-donor-populations
#20
JOURNAL ARTICLE
Oytip Nathalang, Kamonchanok Asisathaporn, Kamphon Intharanut, Wanlapa Chaibangyang, Nipapan Leetrakool, Supattra Mitundee, Sasitorn Bejrachandra
PURPOSE: Coa and Cob antigens of the Colton (CO) blood group system are implicated in acute and delayed hemolytic transfusion reactions (HTRs). Owing to the inadequate supply of specific antiserum, data on CO phenotypes remain limited. This study aimed to develop genotyping methods to predict Coa and Cob antigens and to estimate transfusion-induced alloimmunization risks in three Thai blood donor populations. MATERIALS AND METHODS: The study included 2451 blood samples from unrelated healthy Thai blood donors obtained from central, northern, and southern Thailand...
2023: Journal of Blood Medicine
journal
journal
43392
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.