Raju K Mandal, Munawwar Ali Khan, Arif Hussain, Sajad A Dar, Sultan Aloufi, Arshad Jawed, Mohd Wahid, Aditya K Panda, Mohtashim Lohani, Naseem Akhter, Saif Khan, Bhartendu Nath Mishra, Shafiul Haque
Background: Mannose-binding lectin (MBL) or mannose-binding protein (MBP), encoded by MBL2 gene and secreted by the liver, activates complement system through lectin pathway in innate immunity against the host's infection. Conflictingly, a number of MBL2 variants, rs1800450 (A>B), rs1800451 (A>C), rs5030737 (A>D), rs7096206 (Y>X), rs11003125 (H>L), and rs7095891 (P>Q) allele, have been found to be associated with compromised serum levels and pulmonary tuberculosis (PTB) susceptibility...
2019: Infection and Drug Resistance