journal
Journals Pediatric Allergy, Immunology,...

Pediatric Allergy, Immunology, and Pulmonology

https://read.qxmd.com/read/38864768/a-case-report-and-pediatric-literature-review-povidone-as-a-rare-cause-of-anaphylaxis-in-children
#1
JOURNAL ARTICLE
Sumeyye Baysal, Hulya Anil, Koray Harmanci
Background: Povidone, a synthetic polymer commonly used in various products such as antiseptics, cosmetics, and medications, has been associated with allergic reactions, including anaphylaxis. Despite its widespread use, cases of povidone-induced anaphylaxis, especially in children, are under-recognized. This case report aims to highlight the importance of considering povidone allergy in pediatric patients presenting with anaphylaxis. Case Presentation: We describe a 3-year-old boy who experienced anaphylaxis following the application of povidone-iodine antiseptic solution to a leg wound...
June 12, 2024: Pediatric Allergy, Immunology, and Pulmonology
https://read.qxmd.com/read/38864763/is-it-possible-to-use-inflammatory-markers-as-potential-biomarkers-for-chronic-urticaria
#2
JOURNAL ARTICLE
Gaye Kocatepe, Mehmet Akif Kaya, Aysen Bingol, Dilara Fatma Kocacik Uygun
Background: This study aimed to determine whether the neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII) at admission affect the transition of pediatric patients diagnosed with acute spontaneous urticaria to chronic urticaria. Methods: This study included 390 patients who presented to the Department of Pediatrics at Akdeniz University Hospital with acute spontaneous urticaria between January 2020 and December 2022. A statistical comparison was made between the hematological parameters of patients who developed chronic urticaria and those who did not...
June 12, 2024: Pediatric Allergy, Immunology, and Pulmonology
https://read.qxmd.com/read/38836764/prevalence-and-clinical-characteristics-of-pediatric-lower-airway-malacia-case-series-from-a-tertiary-center-in-turkey
#3
JOURNAL ARTICLE
Fazılcan Zirek, Gizem Özcan, Merve Nur Tekin, Özlem Can Selvi, Nazan Çobanoğlu
Introduction: Lower airway malacia (LAM) is characterized by a reduction in the cross-sectional luminal area during quiet respiration. There is no gold standard diagnostic test; however, flexible fiberoptic bronchoscopy (FFB) is most frequently utilized. The exact prevalence and incidence of LAM are unknown. This study aimed to determine the prevalence rates of pediatric patients diagnosed with LAM, offer a detailed understanding of their demographic and clinical characteristics, and investigate distinctions between two specific types of LAM, namely, tracheomalacia (TM) and bronchomalacia (BM)...
June 5, 2024: Pediatric Allergy, Immunology, and Pulmonology
https://read.qxmd.com/read/38484271/a-bayesian-network-meta-analysis-of-the-effect-of-targeted-therapies-on-the-total-length-of-hospital-stay-in-children-with-drug-induced-stevens-johnson-syndrome-toxic-epidermal-necrolysis-syndrome
#4
JOURNAL ARTICLE
Sahure Ozerturk, Didem Derici Yildirim, Tugba Arikoglu, Semanur Kuyucu, Aylin Kont Ozhan
Background: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare potentially life-threatening hypersensitivity disorders characterized by widespread skin and mucosal involvement. However, there is no standardized evidence-based treatment to reduce the complications of SJS/TEN. This article aims to compare the efficacy of different treatments for pediatric SJS/TEN in terms of length of hospital stay (LOS) using a Bayesian network meta-analysis (NMA). A Bayesian NMA is used to compare and combine evidence from multiple studies and allows clinicians to estimate the relative effectiveness of different treatments/interventions while accounting for heterogeneity in the available evidence...
March 2024: Pediatric Allergy, Immunology, and Pulmonology
https://read.qxmd.com/read/38484270/nirsevimab-a-review
#5
REVIEW
Howard Balbi
Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infections in people of all ages and is the leading cause of hospitalization among infants in the United States. The year 2023 was exciting for RSV prevention. The Food and Drug Administration (FDA) approved 3 new tools for preventing severe lower respiratory tract RSV infections in infants, young children, and elderly persons. In May 2023, the FDA approved 2 vaccines, RSVpreF3 (Arexvy™, GSK) and RSVpreF (Abrysvo™, Pfizer), for adults ages 60 years or older to be given as a single-dose intramuscular injection...
March 2024: Pediatric Allergy, Immunology, and Pulmonology
https://read.qxmd.com/read/38484269/autosomal-recessive-il-12p40-deficiency-due-to-a-mutation-in-the-il12b-gene-report-of-a-brazilian-patient-with-lymph-node-mycobacterial-infection
#6
JOURNAL ARTICLE
Karina Mescouto de Melo, Fabíola Scancetti Tavares, Thales Silva Antunes, Antonio Condino-Neto, Gesmar Rodrigues Silva Segundo, Antônio Carlos Tanajura de Macedo, Alexandre Paz Ferreira, Cláudia França Cavalcante Valente
Background: Autosomal recessive interleukin (IL)-12p40 deficiency is a genetic etiology of Mendelian susceptibility to mycobacterial disease (MSMD). It has been described in ∼50 patients, usually with onset at childhood with Bacille Calmette-Guérin (BCG) and Salmonella infections. Case Presentation: A male patient born to consanguineous parents was diagnosed with presumed lymph node MSMD at the age of 13 years after ocular symptoms. A positive history of inborn error of immunity was present: BCG reaction, skin abscess, and recurrent oral candidiasis...
March 2024: Pediatric Allergy, Immunology, and Pulmonology
https://read.qxmd.com/read/38484267/acknowledgment-of-reviewers-2023
#7
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
March 2024: Pediatric Allergy, Immunology, and Pulmonology
https://read.qxmd.com/read/38484266/artificial-intelligence-in-pediatric-respiratory-diseases-current-status-and-future-promises
#8
JOURNAL ARTICLE
Nemr Eid
No abstract text is available yet for this article.
March 2024: Pediatric Allergy, Immunology, and Pulmonology
https://read.qxmd.com/read/38484265/lung-function-evaluated-by-structured-light-plethysmography-in-children-after-lung-surgery-a-preliminary-analysis
#9
JOURNAL ARTICLE
Michele Ghezzi, Luisa Abbattista, Anna Dighera, Annalisa De Silvestri, Andrea Farolfi, Gloria Pelizzo, Giovanna Riccipetitoni, Sara Costanzo, Valeria Calcaterra, Gian Vincenzo Zuccotti
Background: Structured light plethysmography (SLP) is a novel light-based method that captures chest wall movements to evaluate tidal breathing. Methods: Thirty-two children who underwent lung surgery were enrolled. Their clinical history was collected along with spirometry and SLP. Results: Median age of surgery was 9 months (interquartile range 4-30). Most frequent diagnosis was congenital pulmonary airway malformation (14/32), then pulmonary sequestration (9/32), tumor (5/32), and bronchogenic cyst (4/32)...
March 2024: Pediatric Allergy, Immunology, and Pulmonology
https://read.qxmd.com/read/38324020/participant-perspectives-on-the-implementation-of-a-school-linked-text-message-intervention-to-improve-pediatric-asthma-medication-adherence
#10
JOURNAL ARTICLE
Sonia Radu, Sheerin Zarinafsar, Grace W Ryan, Sanjay Chainani, Sarah Becker, Juliana Arenas, Michelle A Spano, Holly N Shillan, Shushmita Hoque, Rajani Sadasivam, Lori Pbert, Janki Luther, Michelle K Trivedi
Background: Poor adherence to inhaled corticosteroids (ICS) is a significant challenge in pediatric asthma, contributing to health inequities. Text-message reminders for ICS therapy are an evidence-based approach that improves pediatric asthma medication adherence, yet has not been widely adopted into practice, partly due to lack of (1) participant input on design and implementation and (2) use of sustainable community linkages. Remote Asthma Link™ (RAL) seeks to fill this gap as a school-linked text-message intervention wherein parents of children with poorly controlled asthma received daily, 2-way text-message reminders for preventive inhaler use...
February 7, 2024: Pediatric Allergy, Immunology, and Pulmonology
https://read.qxmd.com/read/38236715/acknowledgment-of-reviewers-2023
#11
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
January 17, 2024: Pediatric Allergy, Immunology, and Pulmonology
https://read.qxmd.com/read/38134319/an-unusual-transition-from-cutaneous-to-systemic-mastocytosis-in-a-pediatric-patient
#12
JOURNAL ARTICLE
Keval Patel, Lyda Cuervo-Pardo, Samantha Cresoe, Vanessa Cavero-Chavez
Background: Cutaneous mastocytosis (CM) occurs when abnormal mast cells accumulate in the skin, whereas in systemic mastocytosis (SM), accumulation also occurs in other tissues. A transition from CM to SM is an atypical occurrence in pediatric patients. Case Presentation: An 8-month-old female presented with a 3-month history of whole body hyperpigmented macules with a normal serum tryptase level, consistent with a diagnosis of CM. At age 2.5 years, cutaneous lesions increased and repeat serum tryptase levels were elevated...
December 2023: Pediatric Allergy, Immunology, and Pulmonology
https://read.qxmd.com/read/38134318/pediatric-patients-with-tracheostomies-and-its-multifacet-association-with-lower-airway-infections-an-8-year-retrospective-study-in-a-large-tertiary-center
#13
JOURNAL ARTICLE
Khanh Lai, Yaron Fireizen, Tricia Morphew, Inderpal Randhawa
Background: Lower respiratory tract infections frequently complicate the care of children with chronic tracheostomies. Pediatric patients have significantly more risk to have tracheostomy infections than adults. Better understanding of modifiable risk factors for pulmonary exacerbations may improve the care of technology-dependent children. Methods: A retrospective single-center cohort study conducted on children with tracheostomy and chronic home ventilator to determine the incidence of pulmonary exacerbations leading to hospitalizations, emergency room (ER) visits, and antibiotic prescriptions...
December 2023: Pediatric Allergy, Immunology, and Pulmonology
https://read.qxmd.com/read/38134317/impulse-oscillometry-where-are-we-now
#14
JOURNAL ARTICLE
Rose Hawkins, Ronald Morton, Nemr Eid, Scott Bickel
No abstract text is available yet for this article.
December 2023: Pediatric Allergy, Immunology, and Pulmonology
https://read.qxmd.com/read/38010729/-extl3-associated-immunoskeletal-dysplasia-with-neurodevelopmental-abnormalities-a-lethal-phenotype
#15
JOURNAL ARTICLE
Engin Demir, Filiz Adım, Mehmet Ercüment Döğen, Ayşe Aydoğdu, Edanur Yeşil, Serdar Mermer, Burak Başer, Gizem Ürel Demir
Background: Immunoskeletal dysplasia with neurodevelopmental abnormalities (ISDNA) caused by Exostosin-Like Glycosyltransferase 3 (EXTL3) biallelic mutations is a very rare syndrome with only 16 cases reported in the literature. Skeletal dysplasia, neurodevelopmental delay, immunodeficiency, liver, and kidney cysts are the most common findings of this syndrome. Case Presentation: Here, we report on a patient who exhibited a lethal phenotype with clinical characteristics of this syndrome and had a homozygous pathogenic mutation in EXTL3 gene...
November 20, 2023: Pediatric Allergy, Immunology, and Pulmonology
https://read.qxmd.com/read/37917067/universal-access-to-on-demand-treatment-of-patients-with-hereditary-angioedema-the-chilean-experience
#16
JOURNAL ARTICLE
Juan J Escobar, Joaquín Aguirre, Samuel Ibáñez, Bárbara J Cid, Rolando Campillay, Ana María Gallardo, Masumi Grau, Rodrigo Hoyos-Bachiloglu
Background: In Chile, patients with hereditary angioedema (HAE) type I and type II are protected under Ley Ricarte Soto (LRS), which guarantees access to on demand plasma-derived C1-INH (pdC1-INH) since 2018. We aimed to analyze the first 3 years of LRS. Methods: Review of the LRS database between 2018 and 2021. Results: During the study period, 154 patients were covered by LRS, with an estimated prevalence of HAE in Chile at 0.8:100,000 inhabitants. A delay in diagnosis of 22 years was noted, 50 patients received epinephrine during an attack before the diagnosis of HAE...
November 2, 2023: Pediatric Allergy, Immunology, and Pulmonology
https://read.qxmd.com/read/37729075/drug-rash-with-eosinophilia-and-systemic-symptoms-syndrome-caused-by-itraconazole-in-a-17-year-old-girl
#17
JOURNAL ARTICLE
Helena Pires Pereira, Iolanda Alen Coutinho, Isabel Carrapatoso, Ana Todo-Bom
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a severe adverse drug-induced hypersensitivity reaction. We report a case of DRESS syndrome in a 17-year-old female caused by itraconazole, confirmed by patch testing, that required treatment with both corticotherapy and cyclosporine. Our case highlights the importance of clinical suspicion of this syndrome in pediatric age and the novelty of an antifungal drug being identified as the culprit.
September 20, 2023: Pediatric Allergy, Immunology, and Pulmonology
https://read.qxmd.com/read/37703537/comparison-of-pneumotachometer-and-portable-digital-turbine-spirometry-for-field-based-assessment-an-air-quality-environment-and-respiratory-outcomes-in-bronchopulmonary-dysplasia-study
#18
JOURNAL ARTICLE
Lana Mukharesh, Morgan Ryan, Lystra P Hayden, Suzanne E Dahlberg, Jonathan M Gaffin
Introduction: Data on the use of remote spirometry are limited in the pediatric population. We sought to assess the feasibility and accuracy of a digital turbine spirometer, Medical International Research (MIR) Spirobank Smart (MIR, New Berlin, WI, USA), compared with a pneumotachography spirometer, Pneumotrac (Vitalograph Inc., Lenexa, KS, USA), in field-based clinical research. Methods: This is a cross-sectional study of a subgroup of school-aged participants enrolled in the Air quality, Environment, and Respiratory Outcomes in Bronchopulmonary Dysplasia (BPD) study, who performed same-day paired coached baseline spirometry measurements from the Pneumotrac and MIR devices...
September 2023: Pediatric Allergy, Immunology, and Pulmonology
https://read.qxmd.com/read/37669446/assessing-available-adolescent-self-reported-measures-for-asthma-management-a-systematic-literature-review
#19
REVIEW
Elif Isik, Gardner Mack, Marianna M Sockrider, Nina M Fredland, Ross Shegog
Objective: Asthma is a common chronic disease and a substantial public health problem for children, adolescents, and adults. Adolescence, a period of increased independence and striving for autonomy, is an opportune time for youth transitioning to adulthood to assume more responsibility for their own asthma self-management. However, accurate measures of adolescent asthma outcomes are limited. The purpose of this systematic review is to identify self-reported asthma measures currently available in the empirical literature focused on adolescent populations...
September 2023: Pediatric Allergy, Immunology, and Pulmonology
https://read.qxmd.com/read/37638804/application-of-asthma-prediction-tools-in-a-cohort-of-infants-with-severe-bronchiolitis
#20
JOURNAL ARTICLE
Ronaldo C Fabiano Filho, Ruth J Geller, Ludmilla Candido Santos, Janice A Espinola, Lacey B Robinson, Carlos A Camargo
Background: Severe bronchiolitis is a strong childhood asthma risk factor. Early and accurate asthma prediction is key. We applied the Asthma Predictive Index (API), the modified Asthma Predictive Index (mAPI), and the Pediatric Asthma Risk Score (PARS) in a cohort of high-risk infants to predict asthma at age 6 years. Methods: We conducted a 17-center cohort of infants (age <1 year) hospitalized with severe bronchiolitis during 2011-2014. We used only infancy data to predict asthma at age 6 years. Results: The prevalence of parent-reported asthma at age 6 years was 328/880 (37%)...
September 2023: Pediatric Allergy, Immunology, and Pulmonology
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