journal
https://read.qxmd.com/read/38645695/editorial-72nd-annual-meeting-of-the-italian-society-of-physiology-new-perspectives-in-physiological-research
#1
EDITORIAL
Andrea Gerbino, Grazia Tamma, Fiorenzo Conti, Giovanna Valenti
No abstract text is available yet for this article.
2024: Frontiers in Physiology
https://read.qxmd.com/read/38645694/an-8-month-adapted-motor-activity-program-in-a-young-cmt1a-male-patient
#2
JOURNAL ARTICLE
Giorgio Bottoni, Oscar Crisafulli, Caterina Pisegna, Marco Serra, Sara Brambilla, Fausto Feletti, Giovanni Cremonte, Giuseppe D'Antona
BACKGROUND: It is unclear whether prolonged periods of training can be well tolerated. In Charcot-Marie Tooth disease (CMT). We report the effects of an 8-month, adapted motor activity (AMA) program in a 16-years-old CMT1A male patient. The program included strength, mobility, and balance training (two sessions per week, 1 h per session). MEASURES: Walking ability and walking velocity (Six-Minute Walking Test-6MWT, Ten Meters Walking Test-10 mW T), balance (Y-Balance Test-YBT, Berg Balance Scale-BBS), functional mobility (Short Physical Performance Battery-Short physical performance battery), fatigue (Checklist Individual strength questionnaire - CIS20R), health and quality of life (Short Form Health Survey 36 questionnaire-SF-36) were evaluated in three moments: before (T0), after 5 (T1) and 8 (T2) months of adapted motor activity...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38645693/effect-of-strength-training-with-additional-acupuncture-on-balance-ankle-sensation-and-isokinetic-muscle-strength-in-chronic-ankle-instability-among-college-students
#3
JOURNAL ARTICLE
Shuwan Chang, Yajun Tan, Liang Cheng, Liping Zhou, Bingcheng Wang, Heng Liu
Purpose: The effects of the combination of strength training and acupuncture on chronic ankle instability have not been studied. This study examined effects of strength training combined with acupuncture on balance ability, ankle motion perception, and muscle strength in chronic ankle instability among college students. Methods: Forty-six chronic ankle instability college students were randomly categorized into the experimental group (n = 24, strength training + acupuncture) and the control group (n = 22, strength training) for an 8-week intervention...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38645692/exploring-the-role-of-pyroptosis-in-the-pathogenicity-of-heart-disease
#4
REVIEW
Rohail Bhatti, Priscila Y Sato
Cell death is an essential cellular mechanism that ensures quality control and whole-body homeostasis. Various modes of cell death have been studied and detailed. Unbalanced cell death can lead to uncontrolled cell proliferation (i.e., tumors) or excessive loss of cells (i.e., ischemia injury tissue loss). Thus, it is imperative for modes of cell death to be balanced and controlled. Here, we will focus on a recent mode of cell death called pyroptosis. While extensive studies have shown the role of this route of cell death in macrophages and monocytes, evidence for pyroptosis have expanded to encompass other pathologies, including cancer and cardiac diseases...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38645691/editorial-alternative-and-expanding-views-on-central-respiratory-chemoreception-in-health-and-disease
#5
EDITORIAL
Jaime Eugenín, George B Richerson
No abstract text is available yet for this article.
2024: Frontiers in Physiology
https://read.qxmd.com/read/38645690/individualized-positive-end-expiratory-pressure-reduces-driving-pressure-in-obese-patients-during-laparoscopic-surgery-under-pneumoperitoneum-a-randomized-clinical-trial
#6
JOURNAL ARTICLE
Tiago Batista Xavier, Leonardo Vicente Coelho, Daniel Antonio Lopes Ferreira, José Manuel Cota Y Raposeiras, Marcelo Sampaio Duran, Leticia Almeida Silva, Gabriel Casulari da Motta-Ribeiro, Luciana Moisés Camilo, Alysson Roncally Silva Carvalho, Pedro Leme Silva
INTRODUCTION: During pneumoperitoneum (PNP), airway driving pressure (ΔPRS ) increases due to the stiffness of the chest wall and cephalic shift of the diaphragm, which favors atelectasis. In addition, depending on the mechanical power (MP) formulas, they may lead to different interpretations. METHODS: Patients >18 years of age with body mass index >35 kg/m2 were included in a single-center randomized controlled trial during their admission for bariatric surgery by abdominal laparoscopy...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38645689/understanding-optimal-cadence-dynamics-a-systematic-analysis-of-the-power-velocity-relationship-in-track-cyclists-with-increasing-exercise-intensity
#7
JOURNAL ARTICLE
Anna Katharina Dunst, Clemens Hesse, Olaf Ueberschär
Background: This study aimed to investigate the changes in force-velocity (F/v) and power-velocity (P/v) relationships with increasing work rate up to maximal oxygen uptake and to assess the resulting alterations in optimal cadence, particularly at characteristic metabolic states. Methods: Fourteen professional track cyclists (9 sprinters, 5 endurance athletes) performed submaximal incremental tests, high-intensity cycling trials, and maximal sprints at varied cadences (60, 90, 120 rpm) on an SRM bicycle ergometer...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38645688/characterization-of-three-lamp-genes-from-largemouth-bass-micropterus-salmoides-molecular-cloning-expression-patterns-and-their-transcriptional-levels-in-response-to-fast-and-refeeding-strategy
#8
JOURNAL ARTICLE
Yan-Lin Yang, Wan-Hong Zeng, Yong Peng, Shi-Yu Zuo, Yuan-Qi Fu, Yi-Ming Xiao, Wen-Li Huang, Zheng-Yong Wen, Wei Hu, Yu-Ying Yang, Xiao-Feng Huang
Lysosomes-associated membrane proteins ( LAMPs ), a family of glycosylated proteins and major constituents of the lysosomal membranes, play a dominant role in various cellular processes, including phagocytosis, autophagy and immunity in mammals. However, their roles in aquatic species remain poorly known. In the present study, three lamp genes were cloned and characterized from Micropterus salmoides . Subsequently, their transcriptional levels in response to different nutritional status were investigated. The full-length coding sequences of lamp1 , lamp2 and lamp3 were 1251bp, 1224bp and 771bp, encoding 416, 407 and 256 amino acids, respectively...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38638279/ghrelin-enhances-tubular-magnesium-absorption-in-the-kidney
#9
JOURNAL ARTICLE
Mingzhu Nie, Jing Zhang, Manjot Bal, Claudia Duran, Sung Wan An, Jeffrey M Zigman, Michel Baum, Chitkale Hiremath, Denise K Marciano, Matthias T F Wolf
Osteoporosis after bariatric surgery is an increasing health concern as the rate of bariatric surgery has risen. In animal studies mimicking bariatric procedures, bone disease, together with decreased serum levels of Ca2+ , Mg2+ and the gastric hormone Ghrelin were described. Ghrelin regulates metabolism by binding to and activating the growth hormone secretagogue receptor (GHSR) which is also expressed in the kidney. As calcium and magnesium are key components of bone, we tested the hypothesis that Ghrelin-deficiency contributes to osteoporosis via reduced upregulation of the renal calcium channel TRPV5 and the heteromeric magnesium channel TRPM6/7...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38638278/pole-balancing-on-the-fingertip-model-motivated-machine-learning-forecasting-of-falls
#10
JOURNAL ARTICLE
Minakshi Debnath, Joshua Chang, Keshav Bhandari, Dalma J Nagy, Tamas Insperger, John G Milton, Anne H H Ngu
Introduction: There is increasing interest in developing mathematical and computational models to forecast adverse events in physiological systems. Examples include falls, the onset of fatal cardiac arrhythmias, and adverse surgical outcomes. However, the dynamics of physiological systems are known to be exceedingly complex and perhaps even chaotic. Since no model can be perfect, it becomes important to understand how forecasting can be improved, especially when training data is limited. An adverse event that can be readily studied in the laboratory is the occurrence of stick falls when humans attempt to balance a stick on their fingertips...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38638277/disturbed-flow-regulates-protein-disulfide-isomerase-a1-expression-via-microrna-204
#11
JOURNAL ARTICLE
Leonardo Y Tanaka, Sandeep Kumar, Lucas F Gutierre, Celso Magnun, Daniela Kajihara, Dong-Won Kang, Francisco R M Laurindo, Hanjoong Jo
Redox processes can modulate vascular pathophysiology. The endoplasmic reticulum redox chaperone protein disulfide isomerase A1 (PDIA1) is overexpressed during vascular proliferative diseases, regulating thrombus formation, endoplasmic reticulum stress adaptation, and structural remodeling. However, both protective and deleterious vascular effects have been reported for PDIA1, depending on the cell type and underlying vascular condition. Further understanding of this question is hampered by the poorly studied mechanisms underlying PDIA1 expression regulation...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38638276/wearable-device-for-continuous-sweat-lactate-monitoring-in-sports-a-narrative-review
#12
REVIEW
Geonwoo Yang, Junggi Hong, Seung-Bo Park
In sports science, the use of wearable technology has facilitated the development of new approaches for tracking and assessing athletes' performance. This narrative review rigorously explores the evolution and contemporary state of wearable devices specifically engineered for continuously monitoring lactate levels in sweat, an essential biomarker for appraising endurance performance. Lactate threshold tests have traditionally been integral in tailoring training intensity for athletes, but these tests have relied on invasive blood tests that are impractical outside a laboratory setting...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38638275/evaluation-of-cardiac-pro-arrhythmic-risks-using-the-artificial-neural-network-with-tor-ord-in-silico-model-output
#13
JOURNAL ARTICLE
Nurul Qashri Mahardika T, Ali Ikhsanul Qauli, Aroli Marcellinus, Ki Moo Lim
Torsades de pointes (TdP) is a type of ventricular arrhythmia that can lead to sudden cardiac death. Drug-induced TdP has been an important concern for researchers and international regulatory boards. The Comprehensive in vitro Proarrhythmia Assay (CiPA) initiative was proposed that integrates in vitro testing and computational models of cardiac ion channels and human cardiomyocyte cells to evaluate the proarrhythmic risk of drugs. The TdP risk classification performance using only a single TdP metric may require some improvements because of information limitations and the instability of generalizing results...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38633296/hypoxic-preacclimatization-combining-intermittent-hypoxia-exposure-with-physical-exercise-significantly-promotes-the-tolerance-to-acute-hypoxia
#14
JOURNAL ARTICLE
Jiaxin Xie, Shenwei Xie, Zhifeng Zhong, Huaping Dong, Pei Huang, Simin Zhou, Huaijun Tian, Jijian Zhang, Yu Wu, Peng Li
Background: Both hypoxia exposure and physical exercise before ascending have been proved to promote high altitude acclimatization, whether the combination of these two methods can bring about a better effect remains uncertain. Therefore, we designed this study to evaluate the effect of hypoxic preacclimatization combining intermittent hypoxia exposure (IHE) and physical exercise on the tolerance to acute hypoxia and screen the optimal preacclimatization scheme among the lowlanders. Methods: A total of 120 Han Chinese young men were enrolled and randomly assigned into four groups, including the control group and three experimental groups with hypoxic preacclimatization of 5-day rest, 5-day exercise, and 3-day exercise in a hypobaric chamber, respectively...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38633295/editorial-emerging-aspects-of-ketone-metabolism-in-health-disease
#15
EDITORIAL
Brianna Jane Stubbs, Kenneth M Ford, Jeff Volek
No abstract text is available yet for this article.
2024: Frontiers in Physiology
https://read.qxmd.com/read/38628441/the-effect-of-10%C3%A2-weeks-of-karate-training-on-the-development-of-motor-skills-in-children-who-are-new-to-karate
#16
JOURNAL ARTICLE
Yasin Arslan, Belma Yavaşoğlu, Ayşegül Beykumül, Aylin Özge Pekel, Ceren Suveren, Ebru Olcay Karabulut, Tebessüm Ayyıldız Durhan, Veli Ozan Çakır, Nuriye Sarıakçalı, Hamza Küçük, Levent Ceylan
This study investigated the effect of a 10-week karate training program on the motor skill development of 5-7-year-old children new to karate with two different test batteries. A total of 28 participants were included in the study: 18 in the Karate group and 10 in the control group. The karate group was subjected to a fundamental karate training (kihon) program consisting of 90-minute sessions four days a week for ten weeks in addition to physical education classes at their schools. In contrast, the control group did not participate in any sportive activities except physical education classes in their schools...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38628440/neuronal-nitric-oxide-synthase-required-for-erythropoietin-modulation-of-heart-function-in-mice
#17
JOURNAL ARTICLE
Jeeyoung Lee, Heather M Rogers, Danielle A Springer, Constance T Noguchi
Introduction: Erythropoietin (EPO) acts primarily in regulating red blood cell production mediated by high EPO receptor (EPOR) expression in erythroid progenitor cells. EPO activity in non-erythroid tissue is evident in mice with EPOR restricted to erythroid tissues (ΔEPORE) that become obese, glucose-intolerant, and insulin-resistant. In animal models, nitric oxide synthase (NOS) contributes to EPO activities including erythropoiesis, neuroprotection, and cardioprotection against ischemia-reperfusion injury...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38617060/a-prenatal-acoustic-signal-of-heat-reduces-a-biomarker-of-chronic-stress-at-adulthood-across-seasons
#18
JOURNAL ARTICLE
Eve Udino, Marja A Oscos-Snowball, Katherine L Buchanan, Mylene M Mariette
During development, phenotype can be adaptively modulated by environmental conditions, sometimes in the long-term. However, with weather variability increasing under climate change, the potential for maladaptive long-term responses to environmental variations may increase. In the arid-adapted zebra finch, parents emit "heat-calls" when experiencing heat during incubation, which adaptively affects offspring growth in the heat, and adult heat tolerance. This suggests that heat-call exposure may adjust individual phenotype to hot conditions, potentially compromising individual sensitivity to cool weather conditions...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38617059/a-new-perspective-of-frozen-shoulder-pathology-the-interplay-between-the-brain-and-the-immune-system
#19
REVIEW
Santiago Navarro-Ledesma, Dina Hamed-Hamed, Leo Pruimboom
Frozen shoulder (FS), also known as adhesive capsulitis of the shoulder (FS), is a fibrotic inflammatory process of unknown etiology whose main symptoms are pain, stiffness and the loss of joint mobility. These symptoms may be associated with pathologies such as diabetes, Dupuytren's syndrome and the prevalence of today's sedentary lifestyle. This literature review provides an overview of the epidemiology and pathogenesis of this pathology, as well as the mechanisms of lowgrade chronic inflammation and infection, insulin resistance, and omics-science associated with it...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38617058/a-jump-in-the-atrioventricular-conduction-curve-is-not-caused-by-a-switch-from-fast-pathway-to-slow-pathway-conduction
#20
JOURNAL ARTICLE
Youhua Zhang
Background: A jump in the atrioventricular (AV) conduction curve is the current clinical criterion of dual-pathway electrophysiology. However, the assumption that a jump indicates a switch from fast pathway (FP) to slow pathway (SP) conduction remains unconfirmed. This study was carried out to investigate whether a jump indeed indicates a transition from FP to SP conduction, and if not, what the potential cause is. Methods: Eighty-one experimental records from rabbit AV nodal preparations containing the following data were analyzed: 1) had at least one AV conduction curve and 2) had recording of His electrogram alternans (a validated new index of dual-pathway conduction)...
2024: Frontiers in Physiology
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