Primary Care Companion to CNS Disorders

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Objective: To explore depression prevalence, correlates, impact, and interventions in breast cancer patients, with a focus on the Indian context. Data Sources: The search specifically targeted PubMed as the primary electronic database using keywords such as breast cancer , depression , and India . No date limits were imposed, and studies were restricted to those available in English. Study Selection: A total of 12 studies were reviewed, comprising original research articles and case studies. Inclusion criteria encompassed studies investigating depression in breast cancer patients, irrespective of study design or intervention type...

Objective: To investigate the relationship between social isolation and substance abuse among adult hospitalizations to better target prevention and intervention. Methods: The 2018 National Inpatient Sample dataset was used to identify adult hospitalizations with social isolation and substance abuse in the United States, omitting long-term and rehabilitation facilities. The study analyzed sociodemographic features and health care resource utilization, with primary end points focusing on the prevalence of substance use disorder (SUD) with social isolation and sex/race-based disparities and secondary end points including mental health and costs...

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Objective: The association between childhood separation anxiety disorder (CSAD) and panic disorder (PD) has been demonstrated, although some findings are contradictory. The separation anxiety hypothesis postulates that both CSAD and PD encompass a heightened sensitivity to carbon dioxide (CO2 ). Patients with the respiratory subtype (RS) of PD are known to be more sensitive to CO2 than those from the nonrespiratory subtype (NRS). Therefore, the primary objective centered on the comparative analysis of CSAD prevalence between RS and NRS groups, with secondary objectives focusing on the comparative assessment of RS and NRS groups and the control group...

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Objective: To develop an evidence and consensus-based clinical recommendation (CR) regarding primary care management of insufficient and disturbed sleep associated with concussion/mild traumatic brain injury (mTBI) in service members and veterans. Participants: A multidisciplinary expert working group (EWG) of 23 subject matter experts was selected by the Defense Health Agency (DHA) Traumatic Brain Injury Center of Excellence (TBICoE), based on relevant expertise and experience, from candidates nominated by DHA communities of interest...

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Objective: To examine rates of current posttraumatic stress disorder (PTSD) in adults with trichotillomania and further assess how PTSD impacts symptom severity and functionality. Methods: 209 adults with trichotillomania completed a self-report form for PTSD. The survey was open between April 10, 2023, and May 11, 2023. Independent sample t -tests and Pearson χ2 tests were used to analyze differences in symptom severity and comorbidity presence between participants with and without co-occurring PTSD...

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Objective: To analyze contemporary trends of dementia and dementia-related mortality in the United States between 1999 and 2020 categorized by demographic and regional attributes. Methods: A retrospective cohort analysis was conducted using mortality data from individuals aged 35 years to ≥85 years, where dementia/Alzheimer disease was recorded as a contributing or underlying cause of death. Data were extracted from the US Centers for Disease Control and Prevention's Wide-Ranging Online Data for Epidemiologic Research database for the years 1999-2020...