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Depression Research and Treatment

Vincent Bremer, Burkhardt Funk, Heleen Riper
Self-esteem is a crucial factor for an individual's well-being and mental health. Low self-esteem is associated with depression and anxiety. Data about self-esteem is oftentimes collected in Internet-based interventions through Ecological Momentary Assessments and is usually provided on an ordinal scale. We applied models for ordinal outcomes in order to predict the self-esteem of 130 patients based on diary data of an online depression treatment and thereby illustrated a path of how to analyze EMA data in Internet-based interventions...
2019: Depression Research and Treatment
Berhanu Boru Bifftu, Wubet Worku Takele, Yonas Deressa Guracho, Fekadu Ambaw Yehualashet
Background: Depression is one of the most common mental illnesses affecting around 322 million individual in the world. Although the prevalence of depression is high and its treatment is effective, little is known about its pooled prevalence and help seeking behaviors in the community settings of Ethiopia. Thus, this study aimed to determine the pooled prevalence of depression and its help seeking behaviors in Ethiopia. Methods: A systematic literature search in the databases of Pub-Med, Cochrane, and Google Scholar was performed...
2018: Depression Research and Treatment
Panagiota Katsanou, Nikolaos Tentolouris, Despoina Perrea, Spyridon Katsanos, Vasiliki Ntova, Virginia Antrian, Panagiotis Konstantopoulos, Antonios Politis
Depression is a comorbid condition in patients with Type 2 Diabetes mellitus (T2DM). S100B, a glia derived protein, is linked to depression and has been suggested as a biomarker for depression outcomes in several populations. However, to date there is no data about S100B levels and depression in patients with T2DM. Objective . We hypothesized that S100B serum levels are increased in patients with T2DM and recently diagnosed, drug-free depressive symptoms, and could be used for the diagnosis of depression in T2DM...
2018: Depression Research and Treatment
Alfredo Cancino, Marcelo Leiva-Bianchi, Carlos Serrano, Soledad Ballesteros-Teuber, Cristian Cáceres, Verónica Vitriol
Objective: To identify the clinical and psychosocial factors associated with psychiatric comorbidity in patients consulting for depression in Primary Health Care (PHC) in Chile. Methods: 394 patients with a diagnosis of major depression being treated in a Chilean PHC were evaluated using a sociodemographic and clinical interview, the mini-international neuropsychiatric interview (MINI), a childhood trauma events (CTEs) screening, the intimate partner violence (IPV) scale, the Life Experiences Survey (LES), and the Hamilton Depression Rating Scale (HDRS)...
2018: Depression Research and Treatment
Charles Kwaku Benneh, Robert Peter Biney, Donatus Wewura Adongo, Priscilla Kolibea Mante, Felix Agyei Ampadu, Augustine Tandoh, Jonathan Jato, Eric Woode
Introduction: The stem bark extract of Maerua angolensis DC. (Capparaceae) is used as a traditional remedy for management of anxiety, psychosis, and epilepsy. Aim of the Study: We therefore aimed at evaluating the anxiolytic and antidepressant potential of the plant in mice models. Methods: The dried stem bark was extracted with petroleum ether/ethyl acetate (50:50) mixture to obtain the extract, MAE. We employed Irwin's test to identify the preliminary behavioral and autonomic effects...
2018: Depression Research and Treatment
Wondale Getinet, Tadele Amare, Berhanu Boru, Shegaye Shumet, Wubet Worku, Telake Azale
Introduction: Antenatal depression is a syndrome, in which women experience depressed mood, excessive anxiety, insomnia, and change in weight during the period of pregnancy. Maternal depression negatively influences child outcomes and maternal health. Antenatal depression was measured by different rating scales, namely, BDI, EPDS, and PHQ. The objective of this systematic review was to synthesize logical evidence about the prevalence and potential risk factors of antenatal depression in Ethiopia...
2018: Depression Research and Treatment
Amanual Getnet Mersha, Sileshi Ayele Abebe, Lamessa Melese Sori, Tadesse Melaku Abegaz
Background: There is no pooled evidence regarding the prevalence and potential associated factors of perinatal depression in Ethiopian community. Hence, the current review aimed to examine the prevalence and associated factors of perinatal depression in Ethiopia. Method: A computerized systematic literature search was made in MEDLINE, Scopus, PubMed, ScienceDirect, and Google Scholar. Each database was searched from its start date to January 2018. All included articles were published in English, which evaluated prevalence and associated factors of perinatal depression in Ethiopia...
2018: Depression Research and Treatment
Henok Mulugeta Teshome, Getenet Dessie Ayalew, Fasil Wagnew Shiferaw, Cheru Tesema Leshargie, Dube Jara Boneya
Background: Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. Depression is one of the major important public health problems that is often comorbid with diabetes. Despite the huge effect of comorbid depression and diabetes, the overall pooled prevalence of depression among diabetic patients in the country level remains unknown. Therefore, the objective of this systematic review and meta-analysis is to estimate the pooled prevalence of depression among patients with diabetes mellitus in Ethiopia...
2018: Depression Research and Treatment
Athina Paschou, Dimitrios Damigos, Petros Skapinakis, Kostas Siamopoulos
The purpose of the present study was to investigate the burden and depression in spouses of patients with chronic kidney disease (CKD). The interrelation between burden and depression in family caregivers has been pointed out by previous researches in several chronic diseases and researchers agree that they clearly go together and one cannot talk about one without considering the other. More particularly, in the present study, the caregiver burden, the depression, anxiety, and also health-related quality of life and demographic factors of spouses of patients with CKD were examined, using self-report questionnaires...
2018: Depression Research and Treatment
Sukonthar Ngampramuan, Puttichai Tungtong, Sujira Mukda, Apichat Jariyavilas, Chanin Sakulisariyaporn
Major depressive disorder (MDD) is associated with changes in autonomic nervous system (ANS) and cognitive impairment. Heart rate variability (HRV) and Pulse pressure (PP) parameters reflect influences of the sympathetic and parasympathetic nervous system. Cortisol exerts its greatest effect on the hippocampus, a brain area closely related to cognitive function. This study aims to examine the effect of HRV, PPG, salivary cortisol levels, and cognitive function in MDD patients by using noninvasive techniques...
2018: Depression Research and Treatment
Giovanni Galeoto, Julita Sansoni, Michela Scuccimarri, Valentina Bruni, Rita De Santis, Mariele Colucci, Donatella Valente, Marco Tofani
Objective: The Geriatric Depression Scale (GDS) is an evaluation tool to diagnose older adult's depression. This questionnaire was defined by Yesavage and Brink in 1982; it was designed expressly for the older person and defines his/her degree of satisfaction, quality of life, and feelings. The objective of this study is to evaluate the psychometric properties of the Italian translation of the Geriatric Depression Scale (GDS-IT). Methods: The Italian version of the Geriatric Depression Scale was administered to 119 people (79 people with a depression diagnosis and 40 healthy ones)...
2018: Depression Research and Treatment
Ami Yamamoto, Emi Tsujimoto, Reiko Taketani, Noa Tsujii, Osamu Shirakawa, Hisae Ono
Background: Subthreshold depression and poor stress coping strategies are major public health problems among undergraduates. Interpersonal counseling (IPC) is a brief structured psychological intervention originally designed for use in primary care to treat depressive patients whose symptoms arose from current life stress. Objectives: This study examined the efficacy of IPC in treating subthreshold depression and coping strategies among undergraduates in school counseling...
2018: Depression Research and Treatment
Debra A Dunstan, Ned Scott
Background: The Zung Self-Rating Depression Scale (SDS) and Self-Rating Anxiety Scale (SAS) are two norm-referenced scales commonly used to identify the presence of depression and anxiety in clinical research. Unfortunately, several researchers have mistakenly applied index score criteria to raw scores when assigning clinical significance and symptom severity ratings. This study examined the extent of this problem. Method: 102 papers published over the six-year period from 2010 to 2015 were used to establish two convenience samples of 60 usages of each Zung scale...
2018: Depression Research and Treatment
Stan Kutcher, Yifeng Wei, Heather Gilberds, Adena Brown, Omary Ubuguyu, Tasiana Njau, Norman Sabuni, Ayoub Magimba, Kevin Perkins
Background: This is a report on the outcomes of a training program for community clinic healthcare providers in identification, diagnosis, and treatment of adolescent Depression in Tanzania using a training cascade model. Methods: Lead trainers adapted a Canadian certified adolescent Depression program for use in Tanzania to train clinic healthcare providers in the identification, diagnosis, and treatment of Depression in young people. As part of this training program, the knowledge, attitudes, and a number of other outcomes pertaining to healthcare providers and healthcare practice were assessed...
2017: Depression Research and Treatment
Majid Najafi Kalyani, Nahid Jamshidi, Javad Salami, Elahe Pourjam
Objectives: Students of medical sciences are exposed to many emotional and mental problems. In light of the importance of sleep quality in learning and liveliness, this study was conducted to examine the relationship between psychological variables (stress, anxiety, and depression) and sleep quality of students. Design: This research is a cross-sectional analytical study, where all students studying at Fasa University of Medical Sciences in 2012-2013 year were selected...
2017: Depression Research and Treatment
Simon Wolf, Eric Hahn, Michael Dettling, Main Huong Nguyen, Katja Wingenfeld, Markus Stingl, Bernd Hanewald, Thi Minh Tam Ta
OBJECTIVES: Vietnamese in Germany represent a scarcely researched and vulnerable group for mental health problems, especially under exposure to migration-related stressors (MRS). This study analyzes the effect of those MRS on the severity level and symptom pattern of depression. DESIGN: We analyzed the data of 137 depressed Vietnamese patients utilizing Germany's first Vietnamese psychiatric outpatient clinic. Hierarchical linear regression models were applied to investigate how the quantity of MRS influenced (1) the overall severity of self-reported depression symptoms; (2) the cognitive, affective, and somatic BDI-II subscale; and (3) the single BDI-II items of these subscales...
2017: Depression Research and Treatment
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2017: Depression Research and Treatment
Jenifer A Murphy, Jerome Sarris, Gerard J Byrne
Major depression does not always remit. Difficult-to-treat depression is thought to contribute to the large disease burden posed by depression. Treatment-resistant depression (TRD) is the conventional term for nonresponse to treatment in individuals with major depression. Indicators of the phenomenon are the poor response rates to antidepressants in clinical practice and the overestimation of the efficacy of antidepressants in medical scientific literature. Current TRD staging models are based on anecdotal evidence without an empirical rationale to rank one treatment strategy above another...
2017: Depression Research and Treatment
Rhonda D Szczesniak, Yuanshu Zou, Sophia M Stamper, Daniel H Grossoehme
OBJECTIVE: Spiritual struggle (SS) is associated with poorer health outcomes including depression. The study's main objectives were to characterize change in depression over time, examine longitudinal associations between SS and depression, and determine the extent to which experiencing SS at baseline was predictive of developing depression at follow-up. METHODS: A two-site study collected questionnaire responses of parents (N = 112; 72% female) of children with cystic fibrosis followed longitudinally...
2017: Depression Research and Treatment
Afzal Shamsi, Fardin Amiri, Abbas Ebadi, Musab Ghaderi
BACKGROUND: Thalassemia major has become a public health problem worldwide, particularly in developing and poor countries, while the role of educating the family and community has not been considered enough in patients' care. OBJECTIVES: This study examines the impact of partnership care model on mental health of patients with beta-thalassemia major. MATERIALS AND METHODS: This experimental study, with pretest and posttest design, was performed on patients with beta-thalassemia major in Jiroft city...
2017: Depression Research and Treatment
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