journal
https://read.qxmd.com/read/38979507/race-and-ethnicity-moderate-the-associations-between-lifetime-psilocybin-use-and-past-year-hypertension
#21
JOURNAL ARTICLE
Grant M Jones, Jocelyn A Ricard, Matthew K Nock
BACKGROUND: Hypertension is a major source of morbidity and mortality worldwide, particularly for racial and ethnic minorities who face higher rates of hypertension and worse health-related outcomes. Recent research has reported on protective associations between classic psychedelics and hypertension; however, there is a need to explore how race and ethnicity may moderate such associations. METHODS: We used data from the National Survey on Drug Use and Health (2005-2014) to assess whether race and ethnicity moderate the associations between classic psychedelic use - specifically psilocybin - and past year hypertension...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38979506/perceptions-of-mental-disorder-causes-treatments-and-prevention-among-the-general-population-in-saudi-arabia
#22
JOURNAL ARTICLE
Mohammad Senitan, Abdulhameed Abdullah Alhabeeb, Nora A Althumairi, Mohammed M J Alqahtani, Rashed Abdullah Al-Duraihem, Nasser F BinDhim
This study investigates the community's perception of mental health in Saudi Arabia, emphasizing its influence on attitudes toward the causes, treatment, and prevention of mental health issues. This understanding is vital for creating evidence-based mental health interventions. A cross-sectional national mental health screening was conducted in 2023, utilizing proportional quota sampling for age, gender, and regional representation among 4547 Saudi participants aged 18-90, randomly selected from national databases...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38979505/omega-3-pufas-efficacy-in-the-therapy-of-coronary-artery-disease-combined-with-anxiety-or-depression-a-meta-analysis
#23
JOURNAL ARTICLE
Yiwei Gui, Dongyu He, Junwei Li, Haibin Zhao
OBJECTIVE: The evidence demonstrates that omega-3 polyunsaturated fatty acids (omega-3 PUFAs) protect the cardiovascular system and alleviate anxious or depressive situations. We conducted a meta-analysis to evaluate the effectiveness of omega-3 PUFAs in the treatment of anxiety or depressive states in patients with coronary artery disease. METHODS: This meta-analysis analyzed data from randomized controlled trials to determine the efficacy of omega-3 PUFAs alone or in combination with conventional psychotropic medications in coronary artery disease patients suffering from anxiety or depression...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38979504/commentary-mastery-is-central-an-examination-of-complex-interrelationships-between-physical-health-stress-and-adaptive-cognition-and-social-connection-with-depression-and-anxiety-symptoms
#24
COMMENT
https://read.qxmd.com/read/38979503/enhancing-alzheimer-s-disease-diagnosis-and-staging-a-multistage-cnn-framework-using-mri
#25
JOURNAL ARTICLE
Muhammad Umair Ali, Kwang Su Kim, Majdi Khalid, Majed Farrash, Amad Zafar, Seung Won Lee
This study addresses the pervasive and debilitating impact of Alzheimer's disease (AD) on individuals and society, emphasizing the crucial need for timely diagnosis. We present a multistage convolutional neural network (CNN)-based framework for AD detection and sub-classification using brain magnetic resonance imaging (MRI). After preprocessing, a 26-layer CNN model was designed to differentiate between healthy individuals and patients with dementia. After detecting dementia, the 26-layer CNN model was reutilized using the concept of transfer learning to further subclassify dementia into mild, moderate, and severe dementia...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38979502/editorial-toward-an-understanding-of-neurodevelopmental-disorders-novel-insights-from-molecular-behavioural-and-neuroinflammatory-mechanisms
#26
EDITORIAL
Luca Pangrazzi, Giovanni Provenzano, Giulia Treccani, Luigi Balasco
No abstract text is available yet for this article.
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38979501/applications-of-large-language-models-in-psychiatry-a-systematic-review
#27
JOURNAL ARTICLE
Mahmud Omar, Shelly Soffer, Alexander W Charney, Isotta Landi, Girish N Nadkarni, Eyal Klang
BACKGROUND: With their unmatched ability to interpret and engage with human language and context, large language models (LLMs) hint at the potential to bridge AI and human cognitive processes. This review explores the current application of LLMs, such as ChatGPT, in the field of psychiatry. METHODS: We followed PRISMA guidelines and searched through PubMed, Embase, Web of Science, and Scopus, up until March 2024. RESULTS: From 771 retrieved articles, we included 16 that directly examine LLMs' use in psychiatry...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38979500/-i-feel-so-alone-nothing-emotional-vulnerability-and-detachment-as-transdiagnostic-key-characteristics-of-patients-with-chronic-tinnitus-a-schema-mode-model-approach
#28
JOURNAL ARTICLE
Benjamin Boecking, Petra Brueggemann, Birgit Mazurek
BACKGROUND: Gold-standard approaches for chronic tinnitus involve hearing amplification measures and psychological therapy, where applicable. Whilst schema therapy is accumulating evidence as a transdiagnostically useful treatment framework, its applicability for patients with chronic tinnitus has not yet been examined. The present study (a) explores latent dimensions of psychological distress in a sample of chronic tinnitus patients, and (b) examines whether the schema mode model might explain these dimensions - thus constituting a potentially helpful conceptualization and treatment framework...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38979499/serine-racemase-deletion-alters-adolescent-social-behavior-and-whole-brain-cfos-activation
#29
JOURNAL ARTICLE
Stephanie E Brown, Ziyi Zephyr Wang, Emily L Newman, Elif Engin, Sabina Berretta, Darrick T Balu, Oluwarotimi O Folorunso
BACKGROUND: Neurodevelopmental disorders (NDDs) can cause debilitating impairments in social cognition and aberrant functional connectivity in large-scale brain networks, leading to social isolation and diminished everyday functioning. To facilitate the treatment of social impairments, animal models of NDDs that link N- methyl-D-aspartate receptor (NMDAR) hypofunction to social deficits in adulthood have been used. However, understanding the etiology of social impairments in NDDs requires investigating social changes during sensitive windows during development...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38979498/sensory-phenomenon-assessment-scale-a-new-tool-for-assessment-of-tic-associated-sensations
#30
JOURNAL ARTICLE
Xianbin Wang, Yanlin Li, Liping Yu, Hui Xu, Anyi Zhang, Wenyan Zhang, Zhongliang Jiang, Yonghua Cui, Ying Li
BACKGROUND: Sensory symptoms linked to tic disorder (TD) are challenging to quantify via self- or parent-reported measures. The current study aimed to develop a novel observer-rated semi-structured interview, namely, the Sensory Phenomenon Assessment Scale (SPAS), to aid clinical evaluation on symptoms of TD among children. METHODS: To test its psychometric properties, tic, premonitory urge (PU), and obsessive-compulsive symptoms (OCS) were also assessed in 223 children via the Yale Global Tic Severity Scale (YGTSS), the Premonitory Urge for Tic Scale (PUTS), and the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS)...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38979497/ketamine-in-the-effective-management-of-chronic-pain-depression-and-posttraumatic-stress-disorder-for-veterans-a-meta-analysis-and-systematic-review
#31
REVIEW
Jenny J W Liu, Natalie Ein, Julia Gervasio, Clara Baker, Rachel Plouffe, Sonya Wanklyn, Amer M Burhan, Brenda Lau, Emmanuel Abreu, Thomas Wasiuta, Anthony Nazarov, J Don Richardson
INTRODUCTION: Ketamine has emerged as a promising treatment alternative for the management of chronic pain. Despite encouraging findings in civilian populations, and favourable results from trials examining its efficacy in military populations, there is still a dearth of information pointing to optimal specifications related to ketamine administration for pain, depression, and posttraumatic stress disorder (PTSD) in military populations. This meta-analysis and systematic review synthesised available evidence on the effectiveness, tolerability, and feasibility of ketamine in the management of chronic pain and mental health conditions in military populations...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38979496/autism-spectrum-disorder-and-a-possible-role-of-anti-inflammatory-treatments-experience-in-the-pediatric-allergy-immunology-clinic
#32
REVIEW
Harumi Jyonouchi
Autism spectrum disorder (ASD1 ) is a behaviorally defined syndrome encompassing a markedly heterogeneous patient population. Many ASD subjects fail to respond to the 1st line behavioral and pharmacological interventions, leaving parents to seek out other treatment options. Evidence supports that neuroinflammation plays a role in ASD pathogenesis. However, the underlying mechanisms likely vary for each ASD patient, influenced by genetic, epigenetic, and environmental factors. Although anti-inflammatory treatment measures, mainly based on metabolic changes and oxidative stress, have provided promising results in some ASD subjects, the use of such measures requires the careful selection of ASD subjects based on clinical and laboratory findings...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38979495/childhood-trauma-psychache-and-depression-among-university-students-a-moderated-mediation-model
#33
JOURNAL ARTICLE
Shufeng Chen, Tiantian Fu, Yiwen Wang, Guoxiao Sun
BACKGROUND: Childhood trauma is a potential threat to depression and can have a lifelong impact on the mental health of university students. Our study aimed to construct a moderated mediation model to explore the relationship between childhood trauma, psychache, ambivalence over emotional expression, physical activity, and depression in university students. METHODS: A cross-sectional study was conducted in three universities in China, recruiting 476 university students using self-report questionnaires...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38979494/circulating-inflammatory-cytokines-influencing-schizophrenia-a-mendelian-randomization-study
#34
JOURNAL ARTICLE
Yao-Ting Li, Xuezhen Zeng
INTRODUCTION: Schizophrenia (SCZ) is a severe psychiatric disorder whose pathophysiology remains elusive. Recent investigations have underscored the significance of systemic inflammation, particularly the impact of circulating inflammatory proteins, in SCZ. METHODS: This study explores the potential causal association between certain inflammatory proteins and SCZ. Bidirectional Mendelian randomization (MR) analyses were conducted utilizing data from expansive genome-wide association studies (GWAS)...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38979493/growing-evidence-of-pharmacotherapy-effectiveness-in-managing-attention-deficit-hyperactivity-disorder-in-young-children-with-or-without-autism-spectrum-disorder-a-minireview
#35
REVIEW
Hamza A Alsayouf
Many children with autism spectrum disorder (ASD) also have attention-deficit/hyperactivity disorder (ADHD). ADHD in children is associated with increased risk of negative outcomes, and early intervention is critical. Current guidelines recommend psychosocial interventions such as behavioral training as the first line of therapy in managing ADHD symptoms in children with or without ASD. Where symptoms are refractory to these interventions, medications such as stimulants, α2-adrenergic agonist inhibitors, selective norepinephrine reuptake inhibitors, and second-generation antipsychotics are recommended...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38974920/minding-mentalizing-convergent-validity-of-the-mentalization-breakdown-interview
#36
JOURNAL ARTICLE
Dag Anders Ulvestad, Merete Selsbakk Johansen, Elfrida Hartveit Kvarstein, Geir Pedersen, Theresa Wilberg
OBJECTIVES: Mentalizing difficulties are central to borderline personality disorder (BPD), have severe consequences, and are an explicit focus in mentalization-based treatment. The significance of mentalizing capacity as a predictor or mediator of change is however still uncertain due to a scarcity of research. The Mentalization Breakdown Interview (MBI) was developed as a time saving tool for studying psychotherapy processes and outcome in borderline pathology. This study aimed to investigate the convergent validity of reflective functioning (RF) ratings based on the MBI (MBI-RF) by a comparison with the gold standard, i...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38974919/a-retrospective-chart-review-to-assess-the-impact-of-alpha-guided-transcranial-magnetic-stimulation-on-symptoms-of-ptsd-and-depression-in-active-duty-special-operations-service-members
#37
JOURNAL ARTICLE
Marybeth Bailar-Heath, Riley Burke, Delisha Thomas, Chad D Morrow
INTRODUCTION: Special Operations Forces service members (SOF) are regularly exposed to traumatic and concussive events, increasing the prevalence of symptoms of post-traumatic stress disorder (PTSD) and depression, shortening potential years of service. METHODS: This retrospective chart review presents preliminary data on a Human Performance Optimization (HPO) program that provided an average of 30 sessions of individualized alpha frequency repetitive transcranial magnetic stimulation (α-rTMS) to active-duty SOF as to reduce symptoms of PTSD and depression following traumatic brain injury...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38974918/changes-in-tryptophan-breakdown-associated-with-response-to-multimodal-treatment-in-depression
#38
JOURNAL ARTICLE
Eva Z Reininghaus, Melanie Lenger, Elena M D Schönthaler, Frederike T Fellendorf, Tatjana Stross, Markus Schwarz, Natalie Moll, Bernd Reininghaus, Nina Dalkner
BACKGROUND: Research on depression showed that dysregulations in tryptophan (TRP), kynurenine (KYN), and its KYN pathway metabolites are key aspects in the development and maintenance of depressive symptoms. In our previous reports, we described sex-specific changes in TRP breakdown as well as changes in KYN and KYN/TRP in association with treatment response and inflammatory and metabolic parameters. However, results of treatment effects on KYN pathway metabolites as well as how pathway changes are related to treatment response remain sparse...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38974917/the-methods-and-baseline-characteristics-of-a-multi-site-randomized-controlled-trial-evaluating-mindfulness-based-relapse-prevention-in-conjunction-with-peer-support-to-improve-adherence-to-medications-for-opioid-use-disorders
#39
JOURNAL ARTICLE
Mercy Ngosa Mumba, George Tongi Mugoya, Rebecca S Allen, Andrea L Glenn, Joshua Richman, Anchal Ghera, Austin Butler, Blossom Rogers, Teresa Ann Granger, Lori L Davis
INTRODUCTION: Medications for opioid use disorders (MOUD) remain the gold standard for treating OUD, but treatment initiation and adherence remain challenging. Exclusive utilization of pharmacotherapy as a treatment modality for OUD is sub-optimal, and a combination of psychotherapies and pharmacotherapies is recommended. General trends indicate the benefits of peer mentoring and MBRP separately. Therefore, we hypothesize that the combined effect of MBRP and Peer mentoring will produce synergistic improvements in MOUD adherence compared to an enhanced twelve-step facilitation (TSF)...
2024: Frontiers in Psychiatry
https://read.qxmd.com/read/38974916/what-to-take-up-from-the-patient-s-talk-the-clinician-s-responses-to-the-patient-s-self-disclosure-of-their-subjective-experience-in-the-psychiatric-intake-interview
#40
JOURNAL ARTICLE
Enikö É Savander, Liisa Voutilainen, Jukka Hintikka, Anssi Peräkylä
During psychiatric diagnostic interviews, the clinician's question usually targets specific symptom descriptions based on diagnostic categories for ICD-10/DSM-5 (2, 3). While some patients merely answer questions, others go beyond to describe their subjective experiences in a manner that highlights the intensity and urgency of those experiences. By adopting conversation analysis as a method, this study examines diagnostic interviews conducted in an outpatient clinic in South Finland and identifies sequences that divulge patients' subjective experiences...
2024: Frontiers in Psychiatry
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