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Frontiers in Psychiatry

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https://read.qxmd.com/read/30778305/mental-health-literacy-of-youth-that-have-a-family-member-with-a-mental-illness-outcomes-from-a-new-program-and-scale
#1
Joanne Riebschleger, Shane Costello, Daniel L Cavanaugh, Christine Grové
A program evaluation examined mental health literacy levels and coping outcomes for youth (ages 10-16), before and at the end of their participation in a manualized, school-based mental health literacy program called Youth Education and Support (YES). Most of the youth reportedly had a parent or other family member with a mental health disorder such as depression, anxiety, and/or substance abuse. The mental health literacy levels of program participants from pre to post were evaluated with the developing Knowledge of Mental Illness and Recovery (K-MIR) scale...
2019: Frontiers in Psychiatry
https://read.qxmd.com/read/30766493/resilience-mediates-the-relationship-between-social-support-and-quality-of-life-in-patients-with-primary-glaucoma
#2
Yiwen Wang, Ying Zhao, Sisi Xie, Xinru Wang, Qing Chen, Xiaobo Xia
Objective: Glaucoma is a serious disease causing blindness, which seriously affects the quality of life of patients. Previous studies have reported that both resilience and social support play important roles in enhancing the quality of life of patients with some diseases. The purpose of this study is to investigate if resilience mediates the relationship between social support and quality of life in patients with primary glaucoma. Methods: We conducted a cross-sectional study with 120 patients with primary glaucoma in China...
2019: Frontiers in Psychiatry
https://read.qxmd.com/read/30766492/the-efficacy-of-vortioxetine-on-anhedonia-in-patients-with-major-depressive-disorder
#3
Bing Cao, Caroline Park, Mehala Subramaniapillai, Yena Lee, Michelle Iacobucci, Rodrigo B Mansur, Hannah Zuckerman, Lee Phan, Roger S McIntyre
Background: Anhedonia is a common, persistent, and disabling phenomenon in treated adults with Major Depressive Disorder (MDD). Hitherto, relatively few antidepressant agents have been evaluated with respect to their effect on anhedonia in MDD. Methods: This is a post-hoc analysis of a primary study that sought to evaluate the sensitivity to change of the THINC-integrated tool (THINC-it) in MDD (ClinicalTrials.gov Identifier: NCT03053362). Adults meeting DSM-5 criteria for MDD with at least moderate depressive symptom severity [i...
2019: Frontiers in Psychiatry
https://read.qxmd.com/read/30761025/structural-and-functional-alterations-in-betel-quid-chewers-a-systematic-review-of-neuroimaging-findings
#4
Adellah Sariah, Zhening Liu, Weidan Pu, Haihong Liu, Zhimin Xue, Xiaojun Huang
Background: A number of neuroimaging studies have investigated structural, metabolic, and functional connectivity changes in betel quid (BQ) chewers. We present a systematic review of neuroimaging studies with emphasis on key brain systems affected by BQ chewing to bring a better understanding on the neuro mechanisms involved in BQD. Methods: All BQ neuroimaging studies were identified by searching PubMed, EMBASE, and Google scholar for English articles published until March 2018 using the key words: Betel-quid, resting state, functional MRI, structural MRI, diffusion tensor imaging (DTI), and betel quid dependence basing on the PRISMA criteria...
2019: Frontiers in Psychiatry
https://read.qxmd.com/read/30761024/corrigendum-the-perspectives-associated-with-the-computer-based-diagnostic-method-of-depressive-disorder
#5
Elena Bartkiene, Vesta Steibliene, Virginija Adomaitiene, Vita Lele, Darius Cernauskas, Daiva Zadeike, Dovile Klupsaite, Grazina Juodeikiene
[This corrects the article DOI: 10.3389/fpsyt.2018.00687.].
2019: Frontiers in Psychiatry
https://read.qxmd.com/read/30761023/profiles-of-quality-of-life-in-a-homeless-population
#6
Lia Gentil, Guy Grenier, Jean-Marie Bamvita, Henri Dorvil, Marie-Josée Fleury
Quality of life (QOL) is a key indicator in mental health planning, program evaluation, and evaluation of patient outcomes. Yet few studies have focused on QOL in homeless populations. More specifically, research has yet to identify profiles of homeless individuals based on their QOL using cluster analysis. This study developed a typology of QOL for a sample of 455 homeless individuals recruited from 27 community and public organizations in Quebec (Canada). The typology was developed based on QOL scores, as well as sociodemographic, clinical, and service use variables...
2019: Frontiers in Psychiatry
https://read.qxmd.com/read/30761022/treating-the-e-in-g-%C3%A3-e-trauma-informed-approaches-and-psychological-therapy-interventions-in-psychosis
#7
REVIEW
Olympia Gianfrancesco, Vivien J Bubb, John P Quinn
Despite advances in genetic research, causal variants affecting risk for schizophrenia remain poorly characterized, and the top 108 loci identified through genome-wide association studies (GWAS) explain only 3.4% of variance in risk profiles. Such work is defining the highly complex nature of this condition, with omnigenic models of schizophrenia suggesting that gene regulatory networks are sufficiently interconnected such that altered expression of any "peripheral" gene in a relevant cell type has the capacity to indirectly modulate the expression of "core" schizophrenia-associated genes...
2019: Frontiers in Psychiatry
https://read.qxmd.com/read/30761021/elevated-familial-cardiovascular-burden-among-adolescents-with-familial-bipolar-disorder
#8
Simina Toma, Lisa Fiksenbaum, Danielle Omrin, Benjamin I Goldstein
Background: Bipolar disorder (BD) is one of the most heritable medical conditions, and certain phenotypic characteristics are especially familial in BD. BD is also strongly associated with elevated and premature cardiovascular disease (CVD) morbidity and mortality. Thus, far, little is known regarding the familiality of cardiovascular risk in BD. We therefore examined the extent of CVD-related conditions among relatives of: adolescents with BD with a family history of BD (familial BD), adolescents with BD without a family history of BD (non-familial BD) and healthy controls (HC)...
2019: Frontiers in Psychiatry
https://read.qxmd.com/read/30740064/editorial-deconstructing-the-influence-of-genetic-and-age-vulnerability-to-psychiatric-disorders
#9
EDITORIAL
Cristina Cadoni, Maria Antonietta De Luca
No abstract text is available yet for this article.
2019: Frontiers in Psychiatry
https://read.qxmd.com/read/30723427/editorial-peripheral-markers-of-immune-response-in-major-psychiatric-disorders-where-are-we-now-and-where-do-we-want-to-be
#10
EDITORIAL
Błazej Misiak, Dorota Frydecka, Bartłomiej Stanczykiewicz, Jerzy Samochowiec
No abstract text is available yet for this article.
2019: Frontiers in Psychiatry
https://read.qxmd.com/read/30723426/editorial-neurobiological-perspectives-in-behavioral-addiction
#11
EDITORIAL
Jung-Seok Choi, Daniel Luke King, Young-Chul Jung
No abstract text is available yet for this article.
2019: Frontiers in Psychiatry
https://read.qxmd.com/read/30723425/commentary-gray-matter-structural-alterations-in-social-anxiety-disorder-a-voxel-based-meta-analysis
#12
COMMENT
Janna Marie Bas-Hoogendam
No abstract text is available yet for this article.
2019: Frontiers in Psychiatry
https://read.qxmd.com/read/30778306/web-based-health-services-in-forensic-psychiatry-a-review-of-the-use-of-the-internet-in-the-treatment-of-child-sexual-abusers-and-child-sexual-exploitation-material-offenders
#13
Tamara S N Wild, Peter Fromberger, Kirsten Jordan, Isabel Müller, Jürgen L Müller
In recent years, web-based health services for a variety of mental disorders have been developed and evaluated. Evidence suggests that guided internet-based therapy can be as effective as conventional face-to-face therapy. In forensic psychiatric practice, few web-based treatments have been implemented up to now. However, to our knowledge, there do not yet exist guided internet-based treatments for child sexual abusers and child sexual exploitation material offenders. This review aims at examining under what conditions patients are most likely to benefit from internet-based treatments...
2018: Frontiers in Psychiatry
https://read.qxmd.com/read/30766494/constructing-the-immune-signature-of-schizophrenia-for-clinical-use-and-research-an-integrative-review-translating-descriptives-into-diagnostics
#14
REVIEW
Rune A Kroken, Iris E Sommer, Vidar M Steen, Ingrid Dieset, Erik Johnsen
Schizophrenia is considered a syndrome comprised by several disease phenotypes, covering a range of underlying pathologies. One of these disease mechanisms seems to involve immune dysregulation and neuroinflammation. While the current dopamine receptor-blocking antipsychotic drugs decrease psychotic symptoms and prevent relapse in the majority of patients with schizophrenia, there is a huge need to explore new treatment options that target other pathophysiological pathways. Such studies should aim at identifying robust biomarkers in order to diagnose and monitor the immune biophenotype in schizophrenia and develop better selection procedures for clinical trials with anti-inflammatory and immune-modulating drugs...
2018: Frontiers in Psychiatry
https://read.qxmd.com/read/30761031/psychophysiological-arousal-and-auditory-sensitivity-in-a-cross-clinical-sample-of-autistic-and-non-autistic-anxious-adults
#15
David Nicholas Top, Steven G Luke, Kevin G Stephenson, Mikle South
Many autistic people report overwhelming sensory experiences and also elevated levels of anxiety. Understanding how these experiences are linked to each other can contribute to improved support and intervention for reducing sensory overload and anxiety. This study included 95 young adult participants including autistic adults, non-autistic adults reporting to a psychotherapy clinic with high levels of anxiety, and neurotypical adults with no psychiatric concerns. We measured pupil size using including a baseline task with no auditory stimulus followed by two blocks of simple auditory habituation...
2018: Frontiers in Psychiatry
https://read.qxmd.com/read/30761030/self-regulation-of-breathing-as-an-adjunctive-treatment-of-insomnia
#16
Ravinder Jerath, Connor Beveridge, Vernon A Barnes
Sleep is a quiescent behavioral state during which complex homeostatic functions essential to health and well-being occur. Insomnia is a very common psychiatric disorder leading to a myriad of detrimental effects including loss of concentration, memory, and performance as well as disease. Current pharmaceutical treatments can be expensive, impairing, unhealthy, and habit-forming. Relaxation techniques, such as meditation target the brain and body in contrast to pharmaceutical interventions which solely target neurotransmitter systems in the brain...
2018: Frontiers in Psychiatry
https://read.qxmd.com/read/30761029/antidepressant-effects-of-repetitive-transcranial-magnetic-stimulation-over-prefrontal-cortex-of-parkinson-s-disease-patients-with-depression-a-meta-analysis
#17
Liang Zhou, Zhiwei Guo, Guoqiang Xing, Haitao Peng, Mengjie Cai, Huaping Chen, Morgan A McClure, Lin He, Liangwen Xiong, Bin He, Fei Du, Qiwen Mu
Objective: The purpose of this meta-analysis was to investigate the antidepressant effects of repetitive transcranial magnetic stimulation (rTMS) over the prefrontal cortex (PFC) of patients with Parkinson's disease (PD) and to determine the optimal rTMS parameters, such as the intensity, frequency and the delivered pattern of rTMS stimulation. Methods: EMBASE, PubMed, Web of Science, MEDLINE, and Cochrane data bases were researched for papers published before March 12, 2018. Studies investigating the anti-depression effects of rTMS over PFC in patients with PD were considered...
2018: Frontiers in Psychiatry
https://read.qxmd.com/read/30761028/resting-state-functional-connectivity-of-dorsal-raphe-nucleus-and-ventral-tegmental-area-in-medication-free-young-adults-with-major-depression
#18
Amit Anand, Stephen E Jones, Mark Lowe, Harish Karne, Parashar Koirala
Background: This study has, for the first time, investigated the dorsal raphe nucleus (DRN) and ventral tegmental area (VTA) resting state whole-brain functional connectivity in medication-free young adults with major depression (MDD), at baseline and in relationship to treatment response. Method: A total of 119 subjects: 78 MDD (24 ± 4 years.) and 41 Healthy Controls (HC) (24 ± 3 years) were included in the analysis. DRN and VTA ROIs anatomical templates were used to extract resting state fluctuations and used to derive whole-brain functional connectivity...
2018: Frontiers in Psychiatry
https://read.qxmd.com/read/30761027/two-year-clinical-and-functional-outcomes-of-an-asian-cohort-at-ultra-high-risk-of-psychosis
#19
Chun Ting Chan, Edimansyah Abdin, Mythily Subramaniam, Sarah Ann Tay, Lay Keow Lim, Swapna Verma
Background: To determine the 2-year clinical and functional outcomes of an Asian cohort at ultra-high risk (UHR) of psychosis. Method: This was a longitudinal study with a follow-up period of 2 years on 255 help-seeking adolescents and young adults at UHR of psychosis managed by a multi-disciplinary mental health team in Singapore. Clients received case management, psychosocial, and pharmacological treatment as appropriate. Data comprising symptom and functional outcomes were collected over the observation period by trained clinicians and psychiatrists...
2018: Frontiers in Psychiatry
https://read.qxmd.com/read/30761026/the-group-of-treatment-resistant-schizophrenias-heterogeneity-in-treatment-resistant-schizophrenia-trs
#20
REVIEW
Bruce J Kinon
Schizophrenia is composed of a heterogeneous group of patient segments. Our current notion of the heterogeneity in schizophrenia is based on patients presenting with diverse disease symptom phenotypes, risk factors, structural and functional neuropathology, and a mixed range of expressed response to treatment. It is important for clinicians to recognize the various clinical presentations of resistance to treatment in schizophrenia and to understand how heterogeneity across treatment resistant patient segments may potentially inform new strategies for the development of effective treatments for Treatment Resistant Schizophrenia (TRS)...
2018: Frontiers in Psychiatry
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