Read by QxMD icon Read

Journal of Aging Research

Kazim Sahin, Cemal Orhan, Mehmet Tuzcu, Hakki Tastan, Birdal Bilir, Nurhan Sahin, Deniz Aslar Oner, Omer Kucuk
Purpose: In the present study, we aimed to investigate the effects of tomato powder (TP) on glucose and lipid metabolism, as well as oxidative stress and the NF- κ B, mTOR, and Nrf2 pathways during the aging process in healthy rats. Methods and Results: Male Wistar rats were randomly assigned to four groups as follows: (i) Control group 1 ( n =15, 3-week old): rats were fed standard diet for 7 weeks; (ii) TP group 1 ( n =15, 3-week old): rats were fed standard diet supplemented with TP for 7 weeks; (iii) Control group 2 ( n =15, 8-week old): rats were fed standard diet for 69 weeks; and (iv) TP group 2 (8-week old): rats were fed standard diet supplemented with TP for 69 weeks...
2019: Journal of Aging Research
Alexandra J Horne, Kimberly S Chiew, Jie Zhuang, Linda K George, R Alison Adcock, Guy G Potter, Eleonora M Lad, Scott W Cousins, Frank R Lin, Sara K Mamo, Nan-Kuei Chen, Abigail J Maciejewski, Xuan Duong Fernandez, Heather E Whitson
Despite increased rates of disease, disability, and social losses with aging, seniors consistently report higher levels of subjective well-being (SWB), a construct closely related to happiness, than younger adults. In this exploratory study, we utilized an available dataset to investigate how aspects of health commonly deteriorating with age, including sensory (i.e., vision and hearing) and cognitive status, relate to variability in self-described contributors to happiness. Community-dwelling seniors ( n = 114) responded to a single-item prompt: "name things that make people happy...
2018: Journal of Aging Research
Jamie J Y Lee, Joanna Barlas, Claire L Thompson, Yan Hong Dong
Targeted screening for dementia among older adults in primary healthcare has potential benefits such as better clinical outcomes and the opportunity to access services. Cognitive screening can be followed up by further diagnostic assessment to determine a diagnosis of dementia. Unfortunately, the rates of accepting further diagnostic assessment following cognitive screening are low. The objective of this study was to explore the caregivers' decision-making process regarding uptake of diagnostic assessment following positive screening results...
2018: Journal of Aging Research
Annlia Paganini-Hill, Claudia H Kawas, María M Corrada
Background: Although emerging research has suggested that "positive psychological well-being" is associated with better health outcomes, studies of long-term health and mortality in the elderly are limited. This study assessed the relationship of mental attitude and mortality in older adults followed up for 35 years. Methods: In the 1980s, the Leisure World Cohort Study recruited residents of a California retirement community to a prospective cohort study of health promotion and disease prevention...
2018: Journal of Aging Research
Hadeel Halaweh, Synneve Dahlin-Ivanoff, Ulla Svantesson, Carin Willén
Background: With increasing number of older adults worldwide, promoting health and well-being becomes a priority for aging well. Well-being and physical and mental health are closely related, and this relation may become more vital at older ages as it may contribute to aging well. The state of well-being is a multifaceted phenomenon that refers to an individual's subjective feelings, and exploring perspectives of older adults on aging well is developing to be an important area of research...
2018: Journal of Aging Research
Luís Ângelo Macêdo Santiago, Lídio Gonçalves Lima Neto, Guilherme Borges Pereira, Richard Diego Leite, Cristiano Texeira Mostarda, Janaina de Oliveira Brito Monzani, Wandson Rodrigues Sousa, Aruanã Joaquim Matheus Rodrigues Pinheiro, Francisco Navarro
The aim of this study was to determine the effects of resistance training on the immunologic response, body composition, tumor necrosis factor-alpha (TNF-alpha) gene expression obtained from blood leukocytes, and the cytokines interleukin-6, TNF-alpha, and C-reactive protein (CRP), in the elderly women (mean age 63 ± 2 y). A randomized controlled trial was performed using a bi-set training method for eight weeks in nineteen elderly women. Peripheral blood samples were collected by puncture in pretraining (Pre) and posttraining (Post) moments...
2018: Journal of Aging Research
Varsha Shetty, Mukta N Chowta, Nithyananda Chowta K, Ashok Shenoy, Ashwin Kamath, Priyanka Kamath
Background and Objectives: The drugs most commonly implicated in major potential interactions are those used in the day-to-day clinical management of elderly patients with chronic diseases. This study is planned to evaluate the profile of drug-drug interactions in the medications prescribed to elderly population and also to identify the possible predictors for potential drug-drug interactions in the elderly. Methods: This cross-sectional study included patients aged above 60 years with a minimum of two drugs in the prescriptions...
2018: Journal of Aging Research
Jonathan Desaulniers, Sophie Desjardins, Sylvie Lapierre, Alain Desgagné
The aim of this study was to draw a portrait of the sleep environment of elderly persons living in private households and to determine its relationship with the presence of insomnia. A sample of 599 individuals aged 70 years and older responded to questions about the comfort of their pillow and mattress and the noise level and brightness of their bedroom at night and in the morning. They were also asked whether or not they shared their bed or bedroom with a sleep partner. The Insomnia Severity Index was used to assess insomnia severity...
2018: Journal of Aging Research
Daniel Schniertshauer, Daniel Gebhard, Jörg Bergemann
The process of aging is characterized by the increase of age-associated disorders as well as severe diseases. Due to their role in the oxidative phosphorylation and thus the production of ATP which is crucial for many cellular processes, one reason for this could be found in the mitochondria. The accumulation of reactive oxygen species damaged mitochondrial DNA and proteins can induce mitochondrial dysfunction within the electron transport chain. According to the "mitochondrial theory of aging," understanding the impact of harmful external influences on mitochondrial function is therefore essential for a better view on aging in general, but the measurement of mitochondrial respiration in skin cells from cell cultures cannot completely reflect the real situation in skin...
2018: Journal of Aging Research
Daniel Héctor Verdecchia, Agustina Maria Monzón, Valentina Urbina Jaimes, Fernando Rocha Oliveira, Laércio da Silva Paiva, Tatiana Dias de Carvalho
Objective: To describe the results of a vestibular rehabilitation (VR) program in the timed up and go (TUG), gait speed (GS), and dizziness handicap inventory (DHI) scores for elderly vestibular patients in a developing country. Methods: Descriptive study with retrospective data collected from the clinical records of vestibular patients. The following information was recorded: sex, age, type of vestibular disorder, DHI score, and performance in TUG and GS, before and after participation in a VR program taking place from January 1 to August 30, 2017...
2018: Journal of Aging Research
Heather E Cuevas, Alexa K Stuifbergen, Catherine Ward
Purpose: To describe the experiences of people with type 2 diabetes who have completed a comprehensive cognitive rehabilitation intervention. Method: Nineteen participants with type 2 diabetes enrolled in an 8-week intervention consisting of 4 educational classes to learn strategies to improve cognitive function and an online training program at home to practice cognitively stimulating activities. Two focus groups were conducted as part of a study designed to assess the feasibility of the comprehensive cognitive rehabilitation intervention...
2018: Journal of Aging Research
Chi-Hang Yee, Ching Leung, Yuki Yu-Ting Wong, Sylvia Lee, Jenny Li, Pauline Kwan, Winnie Chiu-Wing Chu, Vincent Chung-Tong Mok, Chi-Fai Ng
Aim: We assessed the impact of cerebral white matter lesions (WMLs) on lower urinary tract symptoms in subjects with normal neurological and cognitive function. Methods: A cohort of community-dwelling subjects aged ≥65 years were recruited to undergo MRI brain assessment. WMLs were graded using the Fazekas scale from 0 to 3. A separate telephone interview was carried out to assess the urinary symptoms in these subjects using the questionnaire Overactive Bladder-Validated 8-Question Awareness Tool (OAB-V8)...
2018: Journal of Aging Research
William Khalil El-Chaer, Clayton Franco Moraes, Otávio Toledo Nóbrega
Although prostate cancer (PCa) is the sixth most common type of neoplasm in the world and the second in prevalence among men (10% of all cases), there is shortage of studies focused on primary prevention of the disorder as well as little understanding on its pathophysiology. Currently, the PCa screening tools are the prostate specific antigen (PSA) dosage conjugated to rectal examination and confirmed by prostate biopsy. Despite the name, the PSA presents reduced specificity, being necessary the identification of new biomarkers that allow an earlier and more precise diagnosis and even better prognosis...
2018: Journal of Aging Research
Hélio José Coelho-Júnior, Bruno Bavaresco Gambassi, Maria-Claudia Irigoyen, Ivan de Oliveira Gonçalves, Paula de Lourdes Lauande Oliveira, Paulo Adriano Schwingel, Cândida Helena Lopes Alves, Ricardo Yukio Asano, Marco Carlos Uchida, Bruno Rodrigues
The present study aimed to investigate whether sarcopenia interferes in the association between HTN and cognitive function in community-dwelling older women. One hundred and eleven older women were recruited and dichotomized in hypertensive ( n =63) and normotensive groups ( n =48). Volunteers underwent evaluations of the sarcopenic state (i.e., skeletal muscle mass, short physical performance battery (SPPB), balance), hemodynamic parameters, and global cognitive status (i.e., Mini-Mental State Examination (MMSE))...
2018: Journal of Aging Research
Gilberto Santos Morais Junior, Nathalia Oliveira Rodrigues, Adriane Dallanora Henriques, Audrey Cecília Tonet-Furioso, Ciro José Brito, Lucy Oliveira Gomes, Clayton Franco Moraes, Otávio Toledo Nóbrega
Background and Aim: Due to the high incidence of vascular diseases, it is necessary to identify new circulating or structural markers for predicting risk for chronic diseases. Some studies suggest that MMP1 gene polymorphisms are associated with the enzyme expression levels in situ (e.g., in atherosclerotic plaques). Objectives: Thus, the study of this polymorphism may help understanding the pathophysiology of coronary disease. Methods: We performed cross-sectional clinical and laboratory evaluations (including measurement of intima-media thickness of carotid arteries) and genotyping of the MMP1 SNP rs495366 (A/G) in 366 elderly people...
2018: Journal of Aging Research
Christina Bermeitinger, Cathleen Kappes
Response priming refers to the finding that a prime stimulus preceding a target stimulus influences the response to the following target stimulus. With young subjects, using moving dot stimuli as primes indicated faster responses to compatible targets (i.e., prime and target are associated with the same response) with short stimulus onset asynchronies (SOAs). In contrast, with longer SOAs, participants responded faster to incompatible targets. In the present study, we extended the evidence by comparing middle-aged (50-65 years) and old (66-87 years) adults...
2018: Journal of Aging Research
Titaporn Worapanwisit, Somkid Prabpai, Ed Rosenberg
Nearly every nation is experiencing rapid population aging. One area of major concern is health; a major health risk for older adults is falling, and there are multiple negative consequences of falling. This is a global concern yet is underresearched in many nations. This study examines demographic, health, and environmental correlates of falling among community-dwelling Thai elderly. Data were collected from a sample of 406 adults aged 60-69. Significant ( p < 0.05) fall correlates were urban residence, older age, greater BMI, impaired and uncorrected vision, chronic health conditions, medication use and medication side effects, poor muscle tone, and hazardous indoor and outdoor home environments...
2018: Journal of Aging Research
Atle Hole Saeterbakken, Hilde Bremseth Bårdstu, Anine Brudeseth, Vidar Andersen
The aim of this study was to determine the effects of a 10-week strength training intervention on isometric strength, rate of force development (RFD), physical function (stair climbing, rising from a chair, and preferred and maximal walking speed), and physical activity among frail elderly people receiving home-care services. Thirty participants were randomly assigned (by sex) to a control group (CON) or a strength training group (ST) performing a supervised training programme using elastic bands, box-lifting, and body weight exercises twice per week...
2018: Journal of Aging Research
Chuntida Kamalashiran, Junya Pattaraarchachai, Sombat Muengtaweepongsa
Dementia is a broad-spectrum terminology for a degenerate in cognitive function severe enough to intervene in activities of daily living. Oxidative stress plays a major role in the neurodegenerative cascade, leading to the irreversible mechanism in dementia. Perilla seed oil is extracted from its seeds and contains a high source of antioxidative substances such as omega-3 fatty acid. With its prominent antioxidative property, perilla seed oil demonstrates neuroprotective effects against dementia in preclinical studies...
2018: Journal of Aging Research
Luis Miguel Rondón García, Jose Manuel Ramírez Navarrro
Background: This research analyzes the impact of quality of life as a metavariable that conditions the health and social welfare of the elderly. The sample of this study is composed of 500 people, randomly selected from the major day centers for the elderly in the province of Granada (Spain). Method: For the inferential analysis, we used the CUBRECAVI questionnaire, which is a multidimensional scale of health and quality of life, along with the Katz and García measure questionnaires, which are also applied to quality of life...
2018: Journal of Aging Research
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"