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Journal of Pain Research

Jens Agerström, Kent Stening, Olof Axman
Background: The ability to traverse psychological distance by going beyond the experienced reality of the self, here and now, is fundamental for effective human functioning. Yet, little is known about how physical pain affects transcendence of psychological distance. Using a construal level theory framework of psychological distance, the current research examines the hypothesis that pain impairs people's ability to traverse any kind of psychological distance whether it be temporal, social, and spatial distance, or the hypothetical...
2019: Journal of Pain Research
Michael Semyonov, Ekaterina Fedorina, Julia Grinshpun, Michael Dubilet, Yael Refaely, Leonid Ruderman, Leonid Koyfman, Michael Friger, Alexander Zlotnik, Moti Klein, Evgeni Brotfain
Background: Patients who undergo surgical procedures that impair the integrity of the chest wall frequently experience extremely severe postoperative pain. Opiates and weaker analgesics, such as nonsteroidal anti-inflammatory drugs (NSAIDs), are not sufficiently effective in achieving control of severe pain and might cause respiratory and gastrointestinal complications. In the past decade, there has been an increased interest in the use of regional nerve blocks for post-thoracoscopy and post-thoracotomy analgesia...
2019: Journal of Pain Research
(no author information available yet)
[This corrects the article on p. 327 in vol. 12, PMID: 30666151.].
2019: Journal of Pain Research
Brandon P Staub, Gianna P Casini, Edward A Monaco, Raymond F Sekula, Trent D Emerick
Purpose: Persistent idiopathic facial pain (PIFP) is a poorly defined and debilitating chronic pain state with a challenging and often inadequate treatment course. This is the first case report identifying the novel use of low-dose lumbar intrathecal ziconotide to successfully treat PIFP with nearly complete resolution of pain and minimal to no side effects. Methods: The patient was a 37 year-old female whose PIFP was refractory to multimodal medication management and multiple neurovascular surgical interventions...
2019: Journal of Pain Research
Eugene R Viscusi, Franck Skobieranda, David G Soergel, Emily Cook, David A Burt, Neil Singla
Purpose: Oliceridine is a novel G protein-biased µ-opioid receptor agonist designed to provide intravenous (IV) analgesia with a lower risk of opioid-related adverse events (ORAEs) than conventional opioids. Patients and methods: APOLLO-1 (NCT02815709) was a phase III, double-blind, randomized trial in patients with moderate-to-severe pain following bunionectomy. Patients received a loading dose of either placebo, oliceridine (1.5 mg), or morphine (4 mg), followed by demand doses via patient-controlled analgesia (0...
2019: Journal of Pain Research
Thavatchai Suvarnnato, Rungthip Puntumetakul, Sureeporn Uthaikhup, Rose Boucaut
Background: Exercise is known to be an important component of treatment programs for individuals with neck pain. The study aimed to compare the effects of semispinalis cervicis (extensor) training, deep cervical flexor (flexor) training, and usual care (control) on functional disability, pain intensity, craniovertebral (CV) angle, and neck-muscle strength in chronic mechanical neck pain. Methods: A total of 54 individuals with chronic mechanical neck pain were randomly allocated to three groups: extensor training, flexor training, or control...
2019: Journal of Pain Research
Francis Sahngun Nahm, Sang-Soep Nahm, Woong Ki Han, Ho Young Gil, Eunjoo Choi, Pyung Bok Lee
Purpose: Complex regional pain syndrome (CRPS) is a rare but refractory pain disorder. Recent advanced information retrieval studies using text-mining and network analysis have suggested nuclear factor kappa B (NFκB) as a possible central mediator of CRPS. The brain is also known to play important roles in CRPS. The aim of this study was to evaluate changes in cerebral NFκB in rats with CRPS. Materials and methods: The chronic post-ischemia perfusion (CPIP) model was used as the CRPS animal model...
2019: Journal of Pain Research
Björn Gerdle, Sophia Åkerblom, Gunilla Brodda Jansen, Paul Enthoven, Malin Ernberg, Huan-Ji Dong, Britt-Marie Stålnacke, Björn O Äng, Katja Boersma
Background: Chronic pain patients frequently suffer from psychological symptoms. There is no consensus concerning the prevalence of severe anxiety and depressive symptoms and the strength of the associations between pain intensity and psychological distress. Although an important aspect of the clinical picture is understanding how the pain condition impacts life, little is known about the relative importance of pain and psychological symptoms for individual's life impact. The aims of this study were to identify subgroups of pain patients; to analyze if pain, psychological distress, and life impact variables influence subgrouping; and to investigate how patients in the subgroups benefit from treatments...
2019: Journal of Pain Research
Xiaoning Li, Shuhong Yang, Liang Wang, Peng Liu, Shuang Zhao, Huizhou Li, Yuqing Jiang, Yuexian Guo, Xiuli Wang
Background: Phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt) is one of the essential signaling pathways for the development and maintenance of neuropathic pain. Objective: To investigate the effect of resveratrol (RES) on paclitaxel-induced neuropathic pain in rats and elucidate the underlying molecular mechanisms. Method: Male Sprague Dawley rats were randomly divided into seven groups (n=10/group): Group C, Group P, Group R, Group R+P, Group LY + R+P, Group LY (the specific inhibitor of PI3K), Group E (the specific inhibitor of sirtuin 1 [SIRT1])...
2019: Journal of Pain Research
Lauren S Penney, Elizabeth Haro
Background: Many leaders in the field of chronic pain treatment consider interdisciplinary pain management programs to be the most effective treatments available for chronic pain. As programs are instituted and expanded to address demands for nonpharmacological chronic pain interventions, we need to better understand how patients experience program impacts, as well as the challenges and supports patients encounter in trying to maintain and build on intervention gains. Methods: We conducted a qualitative evaluation of an interdisciplinary chronic pain coaching program at the Atlanta Veterans Affairs...
2019: Journal of Pain Research
Ellentika Chayadi, Bridget L McConnell
Purpose: This article highlights the influence of attention and pain anticipation on pain attenuation. Pain-related trait anxiety was found to moderate the effect that attention strategies impose on pain perception. This article may contribute to clinical treatments quality, where pain attenuation effect is desired. Participants and methods: One hundred seven participants, comprising of 72 (67%) females and 35 (33%) males between the age of 17 and 48 (M=22.6, SD =4...
2019: Journal of Pain Research
Anfeng Xiang, Yang Yu, Xize Jia, Huibin Ma, Hui Liu, Yu Zhang, Jun Rong, Sheng Liu
Purpose: The present study evaluated the modulation effect of a painless acupuncture technique, ankle acupuncture (AA), on resting-state functional change in patients with chronic low back pain (CLBP). Patients and methods: Fourteen participants diagnosed with CLBP received AA and underwent one brain functional image scan after tactile stimulation and another one following the insertion of the needle. The needling sensations and clinical pain intensities were evaluated after the end of each functional image scan...
2019: Journal of Pain Research
Trang T H Tu, Anna Miura, Yukiko Shinohara, Lou Mikuzuki, Kaoru Kawasaki, Shiori Sugawara, Takayuki Suga, Takeshi Watanabe, Yuma Aota, Yojiro Umezaki, Miho Takenoshita, Akira Toyofuku
Objectives: There has been considerable research which has focused on clarifying the origin of pain in patients with atypical odontalgia (AO), also known as "idiopathic toothache", and on identifying effective treatment, but there has been limited success so far. In this study, we assessed the outcomes of treatment and attempted to identify factors that could account for pain remission in patients with AO. Patients and methods: Data for 165 patients diagnosed with AO from June 2015 to August 2017 were retrospectively reviewed...
2019: Journal of Pain Research
Ivana Vuka, Tihana Marciuš, Svjetlana Došenović, Lejla Ferhatović Hamzić, Katarina Vučić, Damir Sapunar, Livia Puljak
Objective: We conducted a systematic review about patient selection, efficacy, and safety of neuromodulation with electrical field stimulation (EFS) of dorsal root ganglion (DRG) in various painful conditions. We also analyzed conclusion statements as well as conflict of interest and financing of the included studies. Methods: All study designs were eligible for inclusion. We searched MEDLINE, CINAHL, Embase, PsycINFO, and clinical trial registries until September 7, 2018...
2019: Journal of Pain Research
Andrew C Miller, Abbas M Khan, Alberto A Castro Bigalli, Kerry A Sewell, Alexandra R King, Shadi Ghadermarzi, Yuxuan Mao, Shahriar Zehtabchi
Background: Acute abdominal pain (AAP) comprises up to 10% of all emergency department (ED) visits. Current pain management practice is moving toward multi-modal analgesia regimens that decrease opioid use. Objective: This project sought to determine whether, in patients with AAP (population), does administration of butyrophenone antipsychotics (intervention) compared to placebo, usual care, or opiates alone (comparisons) improve analgesia or decrease opiate consumption (outcomes)? Methods: A structured search was performed in Cochrane CENTRAL, CINAHL, Database of Abstracts of Reviews of Effects, Directory of Open Access Journals, Embase, IEEE-Xplorer, Latin American and Caribbean Health Sciences Literature, Magiran, PubMed, Scientific Information Database, Scopus, TÜBİTAK ULAKBİM, and Web of Science...
2019: Journal of Pain Research
Xiaohui Ren, Le Zhang, Qiuxia Xiao, Daxue Huang, Qing Liu, Ying Zhang
Background: COMT gene polymorphism is associated with mental disorders and sensitivity to pain. In this study, we investigated the association between the COMT gene polymorphism and labor anxiety and analgesia in pregnant women. Subjects and methods: A total of 425 pregnant women undergoing labor analgesia were selected from May 2016 to February 2018. The COMT gene polymorphism was detected through the PCR with restriction fragment length polymorphism technique before childbirth...
2019: Journal of Pain Research
Nguyen Van Chuong, Dinh Cong Pho, Nguyen Thi Thanh Thuy, Dinh Toan Nguyen, Nguyen The Luan, Luu Hong Minh, Luong Thi Khai, Nguyen Thuy Linh, Nguyen Trung Kien
Objective: To describe the rate and demographics of pain among Vietnamese people in 48 provinces and describe the impact of pain on individuals, levels of satisfaction with treatment results, and behavior of pain sufferers. Methods: The cross-sectional study was conducted in adults presenting to outpatient clinics throughout 48 provinces in Vietnam and were randomly selected for inclusion in this study. A physician trained to administer a questionnaire in a standardized fashion interviewed each patient and collected data regarding gender, age, career, acute and chronic pain, diagnoses, treatment, and satisfaction with treatment...
2019: Journal of Pain Research
Koji Akeda, Junichi Yamada, Erikka T Linn, Akihiro Sudo, Koichi Masuda
Low back pain (LBP) is now regarded as the first cause of disability worldwide and should be a priority for future research on prevention and therapy. Intervertebral disc (IVD) degeneration is an important pathogenesis of LBP. Platelet-rich plasma (PRP) is an autologous blood concentrate that contains a natural concentration of autologous growth factors and cytokines and is currently widely used in the clinical setting for tissue regeneration and repair. PRP has great potential to stimulate cell proliferation and metabolic activity of IVD cells in vitro...
2019: Journal of Pain Research
Shai N Gozani, Thomas C Ferree, Martin Moynihan, Xuan Kong
Objective: The purpose of this study was to determine if transcutaneous electrical nerve stimulation (TENS) improves sleep in chronic low back pain (CLBP). Background: There is uncertainty over the effectiveness of TENS in CLBP. In most studies, pain intensity has been the primary outcome measure. Although sleep abnormalities are common in CLBP, sleep outcomes have not been evaluated in most studies of TENS effectiveness. Subjective and objective sleep measures are often inconsistent in CLBP, suggesting that perception of sleep and actual sleep may differ...
2019: Journal of Pain Research
Mohammad Hossein Delshad, Sedigheh Sadat Tavafian, Anoshirvan Kazemnejad
Introduction: Health Promotion Model (HPM) is one comprehensive model by which health behavior predicting factors could be determined. Purpose: This study aimed to investigate the effects of a designed interventional program based on HPM on promoting stretching exercise (SE) behavior among office employees. Patients and methods: This interventional designed study was carried out on 87 office employees who were working in the three health networks affiliated to Shahid Beheshti University of Medical Sciences in Tehran, Iran...
2019: Journal of Pain Research
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