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Journals Critical Care Research and Pra...

Critical Care Research and Practice

https://read.qxmd.com/read/38450049/dcrox-and-rox-indices-predict-clinical-outcomes-in-patients-with-covid-19-pneumonia-treated-with-high-flow-nasal-cannula-oxygen-therapy
#1
JOURNAL ARTICLE
Pitchayapa Ruchiwit, Kanpisut Pongtongkam, Narongkorn Saiphoklang
BACKGROUND: High-flow nasal cannula (HFNC) therapy is a common respiratory support in patients with COVID-19 pneumonia. Predictive tools for the evaluation of successful weaning from HFNC therapy for COVID-19 pneumonia have been limited. This study aimed to develop a new predictor for weaning success from HFNC treatment in patients with COVID-19 pneumonia. METHODS: We conducted a retrospective cohort study at Thammasat University Hospital, Thailand. Patients with COVID-19 pneumonia requiring HFNC therapy from April 2020 to September 2021 were included...
2024: Critical Care Research and Practice
https://read.qxmd.com/read/38379715/the-association-of-the-pulmonary-artery-pulsatility-index-and-right-ventricular-function-after-cardiac-surgery
#2
JOURNAL ARTICLE
Johnny Wei, Abigail Kee, Rachel Dukes, Jack Franke, Vincent Leonardo, Brigid C Flynn
BACKGROUND: The pulmonary artery pulsatility index (PAPi) has been shown to correlate with right ventricular (RV) failure in patients with cardiac disease. However, the association of PAPi with right ventricular function following cardiac surgery is not yet established. METHODS: PAPi and other hemodynamic variables were obtained postoperatively for 959 adult patients undergoing cardiac surgery. The association of post-bypass right ventricular function and other clinical factors to PAPi was evaluated using linear regression...
2024: Critical Care Research and Practice
https://read.qxmd.com/read/38328675/plasma-kl-6-as-a-potential-biomarker-for-bronchopulmonary-dysplasia-in-preterm-infants
#3
JOURNAL ARTICLE
Petya Radulova, Margaritka Boncheva, Gencho Nachev, Boriana Slancheva, Violeta Dimitrova
BACKGROUND: KL-6 is a biomarker of interstitial lung injury and increases during repair. AIM: Our aim was to determine the predictive value of plasma KL-6 for the development of bronchopulmonary dysplasia (BPD) in preterm infants. METHODS: Ninety-five extremely preterm infants (EPIs), born at <28 gestational age (GA), were divided into two main BPD groups as follows: the moderate/severe and the no/mild group. KL-6 was analyzed on days 7 and 14...
2024: Critical Care Research and Practice
https://read.qxmd.com/read/38187985/application-of-a-new-type-of-protective-sputum-suction-device-in-clinic-against-cross-infection-between-medical-staff-and-patients
#4
JOURNAL ARTICLE
Kang Lu, Weizhou Wu, Gaomei Jin, Haixia Yang, Xiaowei Cai, Lin Li, Zanchao Chen, Lin Ren, Baoshuan Guo, Qing-Feng Xue
OBJECTIVE: To explore the clinical application of a new type of protective sputum suction device (PSSD) in patients with tracheotomy or tracheal intubation and to evaluate the protective effect of PSSD against cross-infection between medical staffs and patients. METHODS: A novel PSSD was designed which can assist closed sputum suction operation without disconnecting the ventilator. 32 patients with tracheotomy were included to study the protective effect and safety of this device...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/38021314/prevalence-and-mortality-rates-of-acute-kidney-injury-among-critically-ill-patients-a-retrospective-study
#5
JOURNAL ARTICLE
Randa I Farah, Othman A Alfuqaha, Ali R Younes, Hasan A Mahmoud, Alhareth M Al-Jboor, Mohammad M Karajeh, Mohammad Z Al-Masadeh, Omar I Murad, Nathir Obeidat
Acute kidney injury (AKI) poses a significant challenge in critically ill patients. To determine the prevalence, risk factors, and mortality rate of AKI among nonsurgical critically ill patients in Jordan University Hospital, we conducted a retrospective study using a consecutive sampling method, including 457 nonsurgical critically ill patients admitted to the medical intensive care unit (MICU) from January to June 2021. The mean age was 63.8 ± 18 years, with 196 (42.8%) developing AKI during their stay in the MICU...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/38021313/barriers-to-safe-oxygen-therapy-and-the-effect-of-the-training-on-the-knowledge-and-performance-of-icu-nurses
#6
JOURNAL ARTICLE
Samaneh Mirzaei, Mohsen Gholinataj Jelodar, Shahab Rafieian, Farzaneh Sadat Dehghan, Asma Jaafari Nia, Khadijeh Nasiriani, Amir Neshati
INTRODUCTION: Proper oxygen therapy is crucial in hospitals, particularly intensive care units, to ensure safety and accuracy. The role of nurses during oxygen therapy is vital, as their knowledge and correct performance significantly impact patients' clinical conditions. A study was carried out to examine the knowledge and performance of nurses regarding safe oxygen therapy. The study aimed to identify the obstacles hindering safe oxygen therapy and assess the impact of training on the knowledge and performance of intensive care nurses...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/37965250/the-effect-of-listening-to-holy-quran-recital-on-pain-and-length-of-stay-post-cabg-a-randomized-control-trial
#7
JOURNAL ARTICLE
Mohannad Eid Aburuz, Ghadeer Al-Dweik, Fatma Refaat Ahmed
BACKGROUND: Nearly, 75% of patients post-CABG complain of moderate to severe pain during their hospital stay. Nonpharmacological interventions have been investigated; however, the effect of Holy Quran recital post-CABG is still not well studied, especially in developing Islamic countries. OBJECTIVE: To investigate the effect of listening to the Holy Quran recital on pain and length of stay post-CABG. METHODS: This was a randomized control trial on 132 patients recruited from four hospitals in Amman, Jordan...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/37937161/direct-discharge-from-the-critical-care-resuscitation-unit-results-from-a-longitudinal-assessment
#8
JOURNAL ARTICLE
Quincy K Tran, Austin Widjaja, Anya Plotnikova, Jerry Yang, Jacob Epstein, Alexa Aquino, Fernando Albelo, Taylor Kowansky, Isha Vashee, Samuel Austin, Daniel J Haase, Emily Esposito
BACKGROUND: The critical care resuscitation unit (CCRU) facilitates interhospital transfer (IHT) of critically ill patients for immediate interventions. Due to these patients' acuity, it is uncommon for patients to be directly discharged home from this unit, but it does happen on occasion. Since there is no literature regarding outcomes of patients being discharged from a resuscitation unit, our study investigated these patients' outcome at greater than 12 months after being discharged directly from the CCRU...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/37829150/comfort-and-coordination-among-interprofessional-care-providers-involved-in-intubations-in-the-pediatric-intensive-care-unit
#9
JOURNAL ARTICLE
Chetna K Pande, Kelsey Stayer, Thomas Rappold, Madeleine Alvin, Keri Koszela, Sapna R Kudchadkar
BACKGROUND: Successful execution of invasive procedures in acute care settings, including tracheal intubation, requires careful coordination of an interprofessional team. The stress inherent to the intensive care unit (ICU) environment may threaten the optimal communication and planning necessary for the safe execution of this complex procedure. The objective of this study is to characterize the perceptions of interprofessional team members surrounding tracheal intubations in the pediatric ICU (PICU)...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/37822416/the-impact-of-positive-fluid-balance-on-sepsis-subtypes-a-causal-inference-study
#10
JOURNAL ARTICLE
Sharad Patel, Adam Green, Yanika Wolfe, Gregory Felock, Samantha Epstein, Nitin Puri
INTRODUCTION: Sepsis, the leading cause of death in hospitalized patients globally, was investigated in this study, examining the varying effects of positive fluid balance on sepsis subtypes through causal inference. METHODS: In this study, data from the eICU database were utilized, extracting 35 features from sepsis patients. Fluid balance during ICU stay was the treatment, and ICU mortality was the primary outcome. Data preprocessing ensured linear assumptions for logistic regression...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/37795474/rate-of-change-of-rapid-shallow-breathing-index-and-extubation-outcome-in-mechanically-ventilated-patients
#11
JOURNAL ARTICLE
Manjush Karthika, Farhan A Al Enezi, Lalitha V Pillai, Yaseen M Arabi
BACKGROUND: Rapid shallow breathing index (RSBI) has been widely used as a predictor of extubation outcome in mechanically ventilated patients. We hypothesize that the rate of change of RSBI between the beginning and end of a 120-minute spontaneous breathing trial (SBT) could be a better predictor of extubation outcome than a single RSBI measured at the end of SBT in mechanically ventilated patients. Methodology . In this prospective observational study, we enrolled 193 patients who met the inclusion criteria, of whom 33 patients were unable to tolerate a 120-minute SBT and were excluded from the study...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/37795473/impact-of-chronic-kidney-disease-on-clinical-outcomes-during-hospitalization-and-five-year-follow-up-after-coronary-artery-bypass-grafting
#12
JOURNAL ARTICLE
Mohamed Laimoud, Mosleh Nazzel Alanazi, Mary Jane Maghirang, Shatha Mohamed Al-Mutlaq, Suha Althibait, Rasha Ghamry, Rehan Qureshi, Boshra Alanazi, Munirah Alomran, Zeina Bakheet, Zohair Al-Halees
BACKGROUND: Chronic kidney disease (CKD) is often associated with multiple comorbidities including diabetes mellitus, and each has its own complications and impact after cardiac surgery including coronary revascularization. The objective of this work was to study the impact of CKD on clinical outcomes after coronary artery bypass grafting (CABG) and to compare outcomes in patients with different grades of renal functions. We retrospectively reviewed all patients who underwent CABG from January 2016 to August 2020 at our tertiary care hospital using electronic medical records...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/37766780/value-of-diaphragm-ultrasonography-for-extubation-a-single-blinded-randomized-clinical-trial
#13
JOURNAL ARTICLE
T G Toledo, M R Bacci
INTRODUCTION: Daily evaluation of mechanically ventilated (MV) patients is essential for successful extubation. Proper withdrawal prevents complications and reduces the cost of hospitalization in the intensive care unit (ICU). Diaphragm ultrasonography (DUS) has emerged as a potential instrument for determining whether a patient is ready to be extubated. This study compared the efficacy rate of extubation using a standard withdrawal protocol and DUS in patients with MV. METHODS: A randomized, parallel, single-blind, controlled study was conducted on ICU patients undergoing MV...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/37720488/fungal-infections-are-not-associated-with-increased-mortality-in-covid-19-patients-admitted-to-intensive-care-unit-icu
#14
JOURNAL ARTICLE
James Ainsworth, Peter Sewell, Sabine Eggert, Keith Morris, Suresh Pillai
INTRODUCTION: Fungal infection is a cause of increased morbidity and mortality in intensive care patients. Critically unwell patients are at increased risk of developing invasive fungal infections. COVID-19 patients in the intensive care unit (ICU) may be at a particularly high risk. The primary aim of this study was to establish the incidence of secondary fungal infections in patients admitted to the ICU with COVID-19. Secondary aims were to investigate factors that may contribute to an increased risk of fungal infections and to calculate the mortality between fungal and nonfungal groups...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/37637470/early-tracheostomy-may-reduce-the-length-of-hospital-stay
#15
JOURNAL ARTICLE
Fernanda Kazmierski Morakami, Ana Luiza Mezzaroba, Alexandre Sanches Larangeira, Lucienne Tibery Queiroz Cardoso, Carlos Augusto Marçal Camillo, Cintia Magalhães Carvalho Grion
INTRODUCTION: There is evidence that prolonged invasive mechanical ventilation has negative consequences for critically ill patients and that performing tracheostomy (TQT) could help to reduce these consequences. The ideal period for performing TQT is still not clear in the literature since few studies have compared clinical aspects between patients undergoing early or late TQT. OBJECTIVE: To compare the mortality rate, length of stay in the intensive care unit, length of hospital stay, and number of days free of mechanical ventilation in patients undergoing TQT before or after ten days of orotracheal intubation...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/37608868/change-in-antimicrobial-therapy-based-on-bronchoalveolar-lavage-data-improves-outcomes-in-icu-patients-with-suspected-pneumonia
#16
JOURNAL ARTICLE
Bharti Chogtu, Vrinda Mariya Elenjickal, Dharma U Shetty, Mahsheeba Asbin, Vasudeva Guddattu, Rahul Magazine
Flexible bronchoscopy (FB) is often performed in critically ill patients with suspected pneumonia. It is assumed that there will be an association with improved outcomes when bronchoalveolar lavage (BAL) data lead to a change in antimicrobial therapy. Methods. This study included a retrospective cohort of intensive care unit (ICU) patients who underwent FB for a diagnosis of suspected pneumonia. The study compared the outcome of patients in whom antimicrobial modification was carried out based on BAL reports versus those in whom it was not carried out...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/37583653/investigating-the-utility-of-the-sofa-score-and-creating-a-modified-sofa-score-for-predicting-mortality-in-the-intensive-care-units-in-a-tertiary-hospital-in-jordan
#17
JOURNAL ARTICLE
Anas H A Abu-Humaidan, Fatima M Ahmad, Laith S Theeb, Abdelrahman J Sulieman, Abdelkader Battah, Amjad Bani Hani, Mahmoud Abu Abeeleh
BACKGROUND: The utility of the Sequential Organ Failure Assessment (SOFA) score in predicting mortality in the intensive care unit (ICU) has been demonstrated before, but serial testing in various settings is required to validate and improve the score. This study examined the utility of the SOFA score in predicting mortality in Jordanian ICU patients and aimed to find a modified score that required fewer laboratory tests. METHODS: A prospective observational study was conducted at Jordan University Hospital (JUH)...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/37547450/early-neuromuscular-electrical-stimulation-preserves-muscle-size-and-quality-and-maintains-systemic-levels-of-signaling-mediators-of-muscle-growth-and-inflammation-in-patients-with-traumatic-brain-injury-a-randomized-clinical-trial
#18
JOURNAL ARTICLE
Luciana Vieira, Paulo Eugênio Silva, Priscilla Flavia de Melo, Vinicius Maldaner, Joao Q Durigan, Rita de Cassia Marqueti, Otavio Nobrega, Sunita Mathur, Chris Burtin, Fabrício Barin, Wilcelly Machado-Silva, Sergio Ramalho, Gaspar R Chiappa, Nadia Oliveira Gomes, Celso R F Carvalho, Graziella F B Cipriano, Gerson Cipriano
OBJECTIVE: To investigate the effects of an early neuromuscular electrical stimulation (NMES) protocol on muscle quality and size as well as signaling mediators of muscle growth and systemic inflammation in patients with traumatic brain injury (TBI). DESIGN: Two-arm, single-blinded, parallel-group, randomized, controlled trial with a blinded assessment. Setting . Trauma intensive care unit at a university hospital. Participants . Forty consecutive patients on mechanical ventilation (MV) secondary to TBI were prospectively recruited within the first 24 hours following admission...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/37497269/developing-a-preliminary-clinical-prediction-model-for-prognosis-of-pneumonia-complicated-with-heart-failure-based-on-metagenomic-sequencing
#19
JOURNAL ARTICLE
Rongyuan Yang, Yong Duan, Dawei Wang, Qing Liu
BACKGROUND: The predictive factors of prognosis in patients with pneumonia complicated with heart failure (HF) have not been fully investigated yet, especially with the use of next-generation sequencing (NGS) of metagenome. METHODS: Patients diagnosed with pneumonia complicated with HF were collected and divided into control group and NGS group. Univariate and multivariate logistic regression and LASSO regression analysis were conducted to screen the predictive factors for the prognosis, followed by nomogram construction, ROC curve plot, and internal validation...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/37457639/a-systematic-review-and-meta-analysis-of-randomized-controlled-trials-on-supine-vs-nonsupine-endotracheal-intubation
#20
JOURNAL ARTICLE
Chriselyn F Palma, Radwan Mashina, Claire Chen, Tareq Arar, Marwan Mashina, Yussef Al Ghoul, Banreet Dhindsa, Rajany Dy
BACKGROUND: This systematic review and meta-analysis of randomized controlled trials (RCTs) was performed to compare the safety and efficacy of supine vs. nonsupine positions during intubation. METHODS: Based on the literature from inception to October 2020, 13 studies with nonemergent intubation in supine and nonsupine positions were chosen using PRISMA and MOOSE protocols. Pooled estimates were calculated using random-effects models with 95% confidence interval (CI)...
2023: Critical Care Research and Practice
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