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Journals Critical Care Research and Pra...

Critical Care Research and Practice

https://read.qxmd.com/read/38766547/clinical-significance-of-the-prognostic-nutritional-index-in-predicting-delirium-among-critically-ill-patients-a-retrospective-cohort-study
#1
JOURNAL ARTICLE
Feifei Xu, Xi Zhong
Delirium is a serious and complex problem facing critically ill patients. This retrospective study aimed to explore the association between prognostic nutrition index (PNI) and delirium in critically ill patients in the intensive care unit (ICU). This study was based on the Medical Information Mart Intensive Care IV (MIMIC IV) database. Patients over 18 years of age were enrolled. Univariate and multivariate logistic regression analyses were performed to explore the association between PNI and delirium...
2024: Critical Care Research and Practice
https://read.qxmd.com/read/38766546/continuous-infusion-of-ketamine-in-mechanically-ventilated-patients-with-sars-cov-2
#2
JOURNAL ARTICLE
Brian Phan, Afua Agyemang, Walter Klein, Suman B Thapamagar
BACKGROUND: Widespread drug shortages led to higher utilization of ketamine in our intensive care unit, especially among patients with SARS-CoV-2. OBJECTIVES: To evaluate the impact of continuous infusion of ketamine on vasopressor requirements in patients with SARS-CoV-2. METHOD: This was a single-center, retrospective, cohort study comparing mechanically ventilated (MV), adult patients with SARS-CoV-2 receiving either propofol or ketamine for at least 72 hours...
2024: Critical Care Research and Practice
https://read.qxmd.com/read/38742230/practice-and-predictors-of-do-not-resuscitate-orders-in-a-tertiary-care-intensive-care-unit-in-saudi-arabia
#3
JOURNAL ARTICLE
Abdulrahman Asiri, Farhan Zayed Alenezi, Hani Tamim, Musharaf Sadat, Felwa Bin Humaid, Wedyan AlWehaibi, Hasan M Al-Dorzi, Yasir Adnan Alzoubi, Samiyah Alrawey Alanazi, Brintha Naidu, Yaseen M Arabi
INTRODUCTION: The objective of this study was to describe Do-Not-Resuscitate (DNR) practices in a tertiary-care intensive care unit (ICU) in Saudi Arabia, and determine the predictors and outcomes of patients who had DNR orders. METHODS: This retrospective cohort study was based on a prospectively collected database for a medical-surgicalIntensive CareDepartment in a tertiary-care center in Riyadh, Saudi Arabia (1999-2017). We compared patients who had DNR orders during the ICU stay with those with "full code...
2024: Critical Care Research and Practice
https://read.qxmd.com/read/38725586/sequelae-of-severe-acute-respiratory-syndrome-coronavirus-2-sars-cov-2-infection-among-kidney-transplant-recipients-a-large-single-center-experience
#4
JOURNAL ARTICLE
Emily E Zona, Mina L Gibes, Asha S Jain, Juan S Danobeitia, Jacqueline Garonzik-Wang, Jeannina A Smith, Didier A Mandelbrot, Sandesh Parajuli
BACKGROUND: Kidney transplant recipients (KTRs) are a vulnerable immunocompromised population at risk of severe COVID-19 disease and mortality after SARS-CoV-2 infection. We sought to characterize the post-infection sequelae in KTRs at our center. METHODS: We studied all adult KTRs (with a functioning allograft) who had their first episode of SARS-CoV-2 infection between 04/2020 and 04/2022. Outcomes of interest included risk factors for hospitalization, all-cause mortality, COVID-19-related mortality, and allograft failure...
2024: Critical Care Research and Practice
https://read.qxmd.com/read/38716052/questioning-the-role-of-carotid-artery-ultrasound-in-assessing-fluid-responsiveness-in-critical-illness-a-systematic-review-and-meta-analysis
#5
REVIEW
Samuel C D Walker, Adam C Lipszyc, Matthew Kilmurray, Helen Wilding, Hamed Akhlaghi
BACKGROUND: A noninvasive and accurate method of identifying fluid responsiveness in hemodynamically unstable patients has long been sought by physicians. Carotid ultrasound (US) is one such modality previously canvassed for this purpose. The aim of this novel systematic review and meta-analysis is to investigate whether critically unwell patients who are requiring intravenous (IV) fluid resuscitation (fluid responders) can be identified accurately with carotid US. METHODS: The protocol was registered with PROSPERO on the 30/11/2022 (ID number: CRD42022380284)...
2024: Critical Care Research and Practice
https://read.qxmd.com/read/38560481/effects-of-the-high-intensity-early-mobilization-on-long-term-functional-status-of-patients-with-mechanical-ventilation-in-the-intensive-care-unit
#6
JOURNAL ARTICLE
Chuanlin Zhang, Xueqin Wang, Jie Mi, Zeju Zhang, Xinyi Luo, Ruiying Gan, Shaoyu Mu
OBJECTIVE: Intensive care unit (ICU)-acquired weakness often occurs in patients with invasive mechanical ventilation (IMV). Early active mobility may reduce ICU-acquired weakness, improve functional status, and reduce disability. The aim of this study was to investigate whether high-intensity early mobility improves post-ICU discharge functional status of IMV patients. METHODS: 132 adult patients in the ICU who were undergoing IMV were randomly assigned into two groups with a ratio of 1 : 1, with one group received high-intensity early mobility (intervention group, IG), while the other group received conventional treatment (control group, CG)...
2024: Critical Care Research and Practice
https://read.qxmd.com/read/38560480/comparison-of-treatment-approaches-and-subsequent-outcomes-within-a-pulmonary-embolism-response-team-registry
#7
JOURNAL ARTICLE
Anthony J Weekes, Ariana Trautmann, Parker L Hambright, Shane Ali, Angela M Pikus, Nicole Wellinsky, Kelly L Goonan, Sarah Bradford, Nathaniel S O'Connell
OBJECTIVES: To characterize the association between pulmonary embolism (PE) severity and bleeding risk with treatment approaches, outcomes, and complications. METHODS: Secondary analysis of an 11-hospital registry of adult ED patients treated by a PE response team (August 2016-November 2022). Predictors were PE severity and bleeding risk. The primary outcome was treatment approach: anticoagulation monotherapy vs. advanced intervention (categorized as "immediate" or "delayed" based on whether the intervention was received within 12 hours of PE diagnosis or not)...
2024: Critical Care Research and Practice
https://read.qxmd.com/read/38450049/dcrox-and-rox-indices-predict-clinical-outcomes-in-patients-with-covid-19-pneumonia-treated-with-high-flow-nasal-cannula-oxygen-therapy
#8
JOURNAL ARTICLE
Pitchayapa Ruchiwit, Kanpisut Pongtongkam, Narongkorn Saiphoklang
BACKGROUND: High-flow nasal cannula (HFNC) therapy is a common respiratory support in patients with COVID-19 pneumonia. Predictive tools for the evaluation of successful weaning from HFNC therapy for COVID-19 pneumonia have been limited. This study aimed to develop a new predictor for weaning success from HFNC treatment in patients with COVID-19 pneumonia. METHODS: We conducted a retrospective cohort study at Thammasat University Hospital, Thailand. Patients with COVID-19 pneumonia requiring HFNC therapy from April 2020 to September 2021 were included...
2024: Critical Care Research and Practice
https://read.qxmd.com/read/38379715/the-association-of-the-pulmonary-artery-pulsatility-index-and-right-ventricular-function-after-cardiac-surgery
#9
JOURNAL ARTICLE
Johnny Wei, Abigail Kee, Rachel Dukes, Jack Franke, Vincent Leonardo, Brigid C Flynn
BACKGROUND: The pulmonary artery pulsatility index (PAPi) has been shown to correlate with right ventricular (RV) failure in patients with cardiac disease. However, the association of PAPi with right ventricular function following cardiac surgery is not yet established. METHODS: PAPi and other hemodynamic variables were obtained postoperatively for 959 adult patients undergoing cardiac surgery. The association of post-bypass right ventricular function and other clinical factors to PAPi was evaluated using linear regression...
2024: Critical Care Research and Practice
https://read.qxmd.com/read/38328675/plasma-kl-6-as-a-potential-biomarker-for-bronchopulmonary-dysplasia-in-preterm-infants
#10
JOURNAL ARTICLE
Petya Radulova, Margaritka Boncheva, Gencho Nachev, Boriana Slancheva, Violeta Dimitrova
BACKGROUND: KL-6 is a biomarker of interstitial lung injury and increases during repair. AIM: Our aim was to determine the predictive value of plasma KL-6 for the development of bronchopulmonary dysplasia (BPD) in preterm infants. METHODS: Ninety-five extremely preterm infants (EPIs), born at <28 gestational age (GA), were divided into two main BPD groups as follows: the moderate/severe and the no/mild group. KL-6 was analyzed on days 7 and 14...
2024: Critical Care Research and Practice
https://read.qxmd.com/read/38187985/application-of-a-new-type-of-protective-sputum-suction-device-in-clinic-against-cross-infection-between-medical-staff-and-patients
#11
JOURNAL ARTICLE
Kang Lu, Weizhou Wu, Gaomei Jin, Haixia Yang, Xiaowei Cai, Lin Li, Zanchao Chen, Lin Ren, Baoshuan Guo, Qing-Feng Xue
OBJECTIVE: To explore the clinical application of a new type of protective sputum suction device (PSSD) in patients with tracheotomy or tracheal intubation and to evaluate the protective effect of PSSD against cross-infection between medical staffs and patients. METHODS: A novel PSSD was designed which can assist closed sputum suction operation without disconnecting the ventilator. 32 patients with tracheotomy were included to study the protective effect and safety of this device...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/38021314/prevalence-and-mortality-rates-of-acute-kidney-injury-among-critically-ill-patients-a-retrospective-study
#12
JOURNAL ARTICLE
Randa I Farah, Othman A Alfuqaha, Ali R Younes, Hasan A Mahmoud, Alhareth M Al-Jboor, Mohammad M Karajeh, Mohammad Z Al-Masadeh, Omar I Murad, Nathir Obeidat
Acute kidney injury (AKI) poses a significant challenge in critically ill patients. To determine the prevalence, risk factors, and mortality rate of AKI among nonsurgical critically ill patients in Jordan University Hospital, we conducted a retrospective study using a consecutive sampling method, including 457 nonsurgical critically ill patients admitted to the medical intensive care unit (MICU) from January to June 2021. The mean age was 63.8 ± 18 years, with 196 (42.8%) developing AKI during their stay in the MICU...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/38021313/barriers-to-safe-oxygen-therapy-and-the-effect-of-the-training-on-the-knowledge-and-performance-of-icu-nurses
#13
JOURNAL ARTICLE
Samaneh Mirzaei, Mohsen Gholinataj Jelodar, Shahab Rafieian, Farzaneh Sadat Dehghan, Asma Jaafari Nia, Khadijeh Nasiriani, Amir Neshati
INTRODUCTION: Proper oxygen therapy is crucial in hospitals, particularly intensive care units, to ensure safety and accuracy. The role of nurses during oxygen therapy is vital, as their knowledge and correct performance significantly impact patients' clinical conditions. A study was carried out to examine the knowledge and performance of nurses regarding safe oxygen therapy. The study aimed to identify the obstacles hindering safe oxygen therapy and assess the impact of training on the knowledge and performance of intensive care nurses...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/37965250/the-effect-of-listening-to-holy-quran-recital-on-pain-and-length-of-stay-post-cabg-a-randomized-control-trial
#14
JOURNAL ARTICLE
Mohannad Eid Aburuz, Ghadeer Al-Dweik, Fatma Refaat Ahmed
BACKGROUND: Nearly, 75% of patients post-CABG complain of moderate to severe pain during their hospital stay. Nonpharmacological interventions have been investigated; however, the effect of Holy Quran recital post-CABG is still not well studied, especially in developing Islamic countries. OBJECTIVE: To investigate the effect of listening to the Holy Quran recital on pain and length of stay post-CABG. METHODS: This was a randomized control trial on 132 patients recruited from four hospitals in Amman, Jordan...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/37937161/direct-discharge-from-the-critical-care-resuscitation-unit-results-from-a-longitudinal-assessment
#15
JOURNAL ARTICLE
Quincy K Tran, Austin Widjaja, Anya Plotnikova, Jerry Yang, Jacob Epstein, Alexa Aquino, Fernando Albelo, Taylor Kowansky, Isha Vashee, Samuel Austin, Daniel J Haase, Emily Esposito
BACKGROUND: The critical care resuscitation unit (CCRU) facilitates interhospital transfer (IHT) of critically ill patients for immediate interventions. Due to these patients' acuity, it is uncommon for patients to be directly discharged home from this unit, but it does happen on occasion. Since there is no literature regarding outcomes of patients being discharged from a resuscitation unit, our study investigated these patients' outcome at greater than 12 months after being discharged directly from the CCRU...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/37829150/comfort-and-coordination-among-interprofessional-care-providers-involved-in-intubations-in-the-pediatric-intensive-care-unit
#16
JOURNAL ARTICLE
Chetna K Pande, Kelsey Stayer, Thomas Rappold, Madeleine Alvin, Keri Koszela, Sapna R Kudchadkar
BACKGROUND: Successful execution of invasive procedures in acute care settings, including tracheal intubation, requires careful coordination of an interprofessional team. The stress inherent to the intensive care unit (ICU) environment may threaten the optimal communication and planning necessary for the safe execution of this complex procedure. The objective of this study is to characterize the perceptions of interprofessional team members surrounding tracheal intubations in the pediatric ICU (PICU)...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/37822416/the-impact-of-positive-fluid-balance-on-sepsis-subtypes-a-causal-inference-study
#17
JOURNAL ARTICLE
Sharad Patel, Adam Green, Yanika Wolfe, Gregory Felock, Samantha Epstein, Nitin Puri
INTRODUCTION: Sepsis, the leading cause of death in hospitalized patients globally, was investigated in this study, examining the varying effects of positive fluid balance on sepsis subtypes through causal inference. METHODS: In this study, data from the eICU database were utilized, extracting 35 features from sepsis patients. Fluid balance during ICU stay was the treatment, and ICU mortality was the primary outcome. Data preprocessing ensured linear assumptions for logistic regression...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/37795474/rate-of-change-of-rapid-shallow-breathing-index-and-extubation-outcome-in-mechanically-ventilated-patients
#18
JOURNAL ARTICLE
Manjush Karthika, Farhan A Al Enezi, Lalitha V Pillai, Yaseen M Arabi
BACKGROUND: Rapid shallow breathing index (RSBI) has been widely used as a predictor of extubation outcome in mechanically ventilated patients. We hypothesize that the rate of change of RSBI between the beginning and end of a 120-minute spontaneous breathing trial (SBT) could be a better predictor of extubation outcome than a single RSBI measured at the end of SBT in mechanically ventilated patients. Methodology . In this prospective observational study, we enrolled 193 patients who met the inclusion criteria, of whom 33 patients were unable to tolerate a 120-minute SBT and were excluded from the study...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/37795473/impact-of-chronic-kidney-disease-on-clinical-outcomes-during-hospitalization-and-five-year-follow-up-after-coronary-artery-bypass-grafting
#19
JOURNAL ARTICLE
Mohamed Laimoud, Mosleh Nazzel Alanazi, Mary Jane Maghirang, Shatha Mohamed Al-Mutlaq, Suha Althibait, Rasha Ghamry, Rehan Qureshi, Boshra Alanazi, Munirah Alomran, Zeina Bakheet, Zohair Al-Halees
BACKGROUND: Chronic kidney disease (CKD) is often associated with multiple comorbidities including diabetes mellitus, and each has its own complications and impact after cardiac surgery including coronary revascularization. The objective of this work was to study the impact of CKD on clinical outcomes after coronary artery bypass grafting (CABG) and to compare outcomes in patients with different grades of renal functions. We retrospectively reviewed all patients who underwent CABG from January 2016 to August 2020 at our tertiary care hospital using electronic medical records...
2023: Critical Care Research and Practice
https://read.qxmd.com/read/37766780/value-of-diaphragm-ultrasonography-for-extubation-a-single-blinded-randomized-clinical-trial
#20
JOURNAL ARTICLE
T G Toledo, M R Bacci
INTRODUCTION: Daily evaluation of mechanically ventilated (MV) patients is essential for successful extubation. Proper withdrawal prevents complications and reduces the cost of hospitalization in the intensive care unit (ICU). Diaphragm ultrasonography (DUS) has emerged as a potential instrument for determining whether a patient is ready to be extubated. This study compared the efficacy rate of extubation using a standard withdrawal protocol and DUS in patients with MV. METHODS: A randomized, parallel, single-blind, controlled study was conducted on ICU patients undergoing MV...
2023: Critical Care Research and Practice
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