Vladyslav Povoroznyuk, Nataliia Grygorieva, Helena Johansson, Mattias Lorentzon, Nicholas C Harvey, Eugene V McCloskey, Anna Musienko, Enwu Liu, John A Kanis, Nataliia Zaverukha, Oksana Ivanyk
Objectives: Osteoporosis, in addition to its consequent fracture burden, is a common and costly condition. FRAX® is a well-established, validated, web-based tool which calculates the 10-year probability of fragility fractures. A FRAX model for Ukraine has been available since 2016 but its output has not yet been translated into intervention thresholds for the treatment of osteoporosis in Ukraine; we aimed to address this unmet need in this analysis. Methods: In a referral population sample of 3790 Ukrainian women, 10-year probabilities of major osteoporotic fracture (MOF) and hip fracture separately were calculated using the Ukrainian FRAX model, with and without femoral neck bone mineral density (BMD)...
2021: Journal of Osteoporosis