Journal of Pharmacy & Bioallied Sciences

UNLABELLED: This study investigates the effectiveness of nanoparticles in preventing the formation of biofilms on orthodontic brackets. Biofilm formation is a common concern during orthodontic treatment, as it can lead to oral health issues. MATERIALS AND METHODS: The study utilized a randomized controlled trial design. The participants were divided into two groups: the experimental group and the control group. The experimental group received orthodontic brackets coated with nanoparticles, while the control group received regular brackets...

AIM AND OBJECTIVE: This study was intended for a possible relationship that might exist between exercise addiction and unbending commitment among female amateur runners. Exercise addiction (EA) can be characterized as an obsession with physical activity. MATERIALS AND METHODS: The "purposive sampling method" was utilized to collect data. The inventories taken for this purpose were "The Exercise Addiction Inventory" and "Commitment Running Scale." The questionnaire was filled out by 100 participants aged between 18 and 50 years from the capital of India and its border area (Delhi and NCR)...

BACKGROUND AND OBJECTIVES: Although immunization against coronavirus disease 2019 (COVID-19) is ongoing, adverse reactions to these vaccinations have been observed in isolated cases. We aimed to report different neurological complications developed after COVID-19 vaccination. MATERIALS AND METHODS: In our case series study, we report all cases of CNS demyelination following COVID-19 immunization. Clinical evaluation, brain MRI, and CSF analysis for oligoclonal bands and IgG index were performed for all patients...

INTRODUCTION: Alteration in the various markers is seen in diabetic nephropathy (DN). In the current research, four different markers were evaluated and were examined for their diagnostic value in the nephropathic type 2 diabetes patients. METHODS: A prospective clinical trial was piloted with diabetic male subjects with nephropathy. The subjects were followed up for 9 months. Thirty subjects were recruited as type 2 diabetes mellitus patients without nephropathy as controls...

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Traumatic dental injuries (TDIs) have significant long-term consequences for the oral cavity's hard and soft tissues. Alveolar process fractures are particularly complicated. This case report describes the management and 12-month follow-up of a segmental maxillary alveolar process fracture involving laterally luxated primary incisors. A case of a 4-year-old boy was reported to the hospital 1 hour after an accidental fall at school, which resulted in a fracture of the maxillary alveolar process. Emergency treatment consisted of fracture reduction and repositioning of the primary incisors, followed by a semirigid splint between maxillary canines...

BACKGROUND AND OBJECTIVES: Numerous therapeutic and dietary interventions have been examined in the last thirty years for pediatric patients diagnosed with autism spectrum disorder (ASD). Our interventional study aimed to assess the effectiveness of the gluten-free, casein-free (GFCF) diet in a cohort of Egyptian children with ASD. MATERIALS AND METHODS: The present clinical trial was conducted as a prospective 12-month, open-label, case-controlled interventional study...

OBJECTIVE: Using cone beam computed tomography (CBCT), this study compared three rotary file systems-XP Endoshaper, Hyflex CM, and K3 XF-for centering, canal transportation, and root canal area growth. MATERIALS AND METHODS: The rotating file system randomly separated 60 removed human mandibular molars into three groups ( n = 20). Manufacturer-recommended root canal instrumentation was done. Specialized software examined pre- and post-instrumentation CBCT scans...

AIM: This study was done for the efficacy assessment of cognitive behavioral therapy (CBT) and various relaxation techniques in patients with suicidal tendencies. METHODOLOGY: The study was conducted among 150 patients of attempted suicide for a period of 2 years (January 2017 to January 2019). The participants were randomly allocated into three groups, with 50 patients each receiving CBT, JPMR, and combined treatment (groups I, II, and III, respectively). The Beck Scale for Suicide Ideation (BSI) and the Columbia-Suicide Severity Rating Scale (C-SSRS) score were used for pre- and postassessment of depression in the patients...

INTRODUCTION: Using three-dimensional printed duplicates of the donor teeth, three-dimensional auto-transplantation is a medical procedure that moves a tooth from one location inside a patient to another. The intraoperative practicability during 3D auto-transplantation of teeth was evaluated in the present study. MATERIAL AND METHODS: A prospective multicenter clinical study was done among the subjects. "Preoperative cone-beam computed tomography imaging," "computer-assisted design (CAD)," and "computer-assisted manufacturing (CAM)" were used in all operations to make a 3D duplicate of the donor teeth...

BACKGROUND: Effective endodontic instrumentation aims to remove microorganisms, debris, and tissue from the root canal while maintaining dentinal integrity. This study compares dentinal defect incidence following canal preparation with different hand files, nickel-titanium rotary files, and reciprocating files. MATERIALS AND METHODS: Eighty single-rooted mandibular premolars with mature apices were collected. Four groups ( n = 20) were established based on canal patency establishment, canal preparation technique, irrigation solution, and final irrigation...

This study aims to highlight the challenges that undergraduates face when traveling a significant distance from home to study. These challenges are psychological, financial, and nutritional. The study was descriptive and based on a survey conducted to investigate the challenges faced by university students while studying away from their hometown. A questionnaire was used to collect data from 214 undergraduates between February and April 2021. The collected data were analyzed using the computer program SPSS version 24...

AIM: The aim of the present study was to determine the prevalence of paraplegia-related fear in spinal anesthesia among the general population in the central region of Saudi Arabia. MATERIALS AND METHODS: A total of 371 participants were given a pretested, precoded, questionnaire was used to collect data to assess the prevalence of fear of paraplegia in spinal anesthesia. The questionnaire contained questions to assess variables like the extent of fear, causes, gender preponderance, any false information about paraplegia in spinal anesthesia, and complications experienced after receiving spinal anesthesia...

INTRODUCTION: In today's healthcare environment, peripheral venous cannulations are frequently performed procedures. Bloodstream infections could occur as a result of the intrusive operation. Peripheral venous cannulas should be inserted and managed according to specific rules. This study compared these standards to the peripheral venous cannulation procedure and results at a teaching hospital institution. MATERIALS AND METHODS: This study investigated the procedure and results of peripheral venous cannulation in a teaching center using a prospectively completed audit loop study...

The present study aimed to evaluate the effect of denture wearing on the occurrence of fungal isolates in the oral cavity before and after complete denture insertion. Fifty completely edentulous patients were selected. Swab samples were collected intraorally before the fabrication of complete dentures from the palatal mucosal surface and after complete denture fabrication (1 and 7 days after denture insertion). Further, these samples were inoculated and incubated. Results showed that in 48 patients, no isolate of fungus before denture insertion was found...

BACKGROUND: Pediatric facial fractures are fairly uncommon injuries and comprise less than 15% of all facial fractures in the literature. OBJECTIVES: To analyze the pattern of pediatric facial fractures and compare the results with similar studies performed in India and the rest of the world. MATERIALS AND METHODS: A total of 231 patients were admitted for the treatment of maxillofacial fractures. Data on etiology, anatomical location, mode of treatment, duration of stay, and X-ray advice were recorded...

UNLABELLED: The transfer of interocclusal data from the patient's mouth to articulators utilizing various types of recording media is necessary for the production of dental prostheses. Occlusal errors in the final prosthesis result from any discrepancies in these interocclusal records. MATERIALS AND METHODS: The purpose of this study was to assess the linear dimensional changes in the four elastomeric interocclusal recording materials as well as the material's resistance to compression during the cast mounting on the articulator...

OBJECTIVE: This study used spectrophotometry to examine how staining beverages affect the color stability of three commercial composite materials (nanohybrid composite (A), bulk fill composite (B), and flowable composite (C)) over time. MATERIALS AND METHODS: Composite discs were randomly divided into groups. The specimens were kept in coffee, tea, red wine, and cola for 14 days at 37°C in the dark. At baseline, 7 days, and 14 days, spectrophotometers measured color...

BACKGROUND: Accurate assessment of impacted canines is crucial for successful treatment planning. Radiographic techniques like Cone Beam Computed Tomography (CBCT) and Panoramic Radiography are commonly used, but their comparative accuracy remains under scrutiny. MATERIALS AND METHODS: In this study, 50 patients diagnosed with impacted canines were enrolled. Both CBCT and Panoramic Radiography images were obtained for each patient using standard protocols. Two experienced dentists independently analyzed the images to determine the position of impacted canines and their relationship with neighboring structures...

BACKGROUND: This study compares the effectiveness of laser-assisted periodontal therapy (LAPT) to conventional scaling and root planing (SRP) in the treatment of periodontal disease. MATERIALS AND METHODS: Patients with periodontal disease were divided into two groups. One group received LAPT, while the other group underwent conventional SRP. The periodontal parameters, including pocket depth (PD) and clinical attachment level (CAL), were measured before and after the treatments...