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Journal of Pharmacy & Bioallied Sciences

Evgenii Plotnikov, Elena Korotkova, Olesya Voronova
Objective: Aim of the present work was to study the antioxidant properties of lithium salts of Krebs cycle substrates and their influence on immune cells. Lithium is a well-known and widely used mood stabilizer. These lithium-based substances have a lot of potential properties because of the anionic component of the Krebs cycle substrates, which take part in basic intracellular biochemical process. Materials and Methods: Lithium salts of fumarate, pyruvate, malate, succinate, and citrate (as reference drug) were investigated in this study as antioxidants and immunomodulators...
October 2018: Journal of Pharmacy & Bioallied Sciences
Aimi M Mohd Yusof, Nor A A Rahman, Mainul Haque
Background: Food poisoning (FP) commonly occurs because of consuming contaminated food, which can be fatal. Many people are not aware of the dangers of FP. Thus, the purpose of this study is to analyze the knowledge, attitude, and practice (KAP) of FP among dietetic students (DS) and food handlers (FH) in a public university in Malaysia. Materials and Methods: A cross-sectional study was designed, and a self-administered questionnaire was distributed to 106 respondents...
October 2018: Journal of Pharmacy & Bioallied Sciences
Allan Mathews, Abul Kalam Azad, Syed A Abbas, Farid Z Bin Che Rose, A B M Helal Uddin
Background: In Malaysia, community pharmacies play an important and vital role in both urban and rural areas with approximately 30% of 12,000 registered pharmacists with annual retention certificate practicing in community pharmacies. The main objective of this study was to find the perception of respondents on the value and necessity of pharmacists. Materials and Methods: The questionnaire was divided into two sections: the first section assessed the visits to community pharmacies, purpose, interaction with pharmacy staffs, professional fee, and improvements to pharmacy practices; the second section evaluated the characteristics of respondents including an e-consent form...
October 2018: Journal of Pharmacy & Bioallied Sciences
Shahid Mitha, Mohamed Hassan ElNaem, Jaganmohan Chandran, Nishakaran Pushpa Rajah, Tay Yi Fam, Muneer Gohar Babar, Mohammad Jamshed Siddiqui, Shazia Jamshed
Background and Objectives: Various devices have been used to maintain oral hygiene. These include toothbrush and toothpaste, mouthwash, dental floss, miswak, and toothpick. This study attempts to investigate the use of various oral cleaning devices and their perceived benefits among Malaysians. Methods: A quantitative cross-sectional study conducted in two different cities of Malaysia. A convenience sampling approach was adopted. A total of 787 participants agreed to participate in the current research...
October 2018: Journal of Pharmacy & Bioallied Sciences
Mohammad Azadbakht, Taha Monadi, Zahra Esmaeili, Aroona Chabra, Naser Tavakoli
Aim: Glycyrrhiza glabra ( G. glabra ) or licorice with isoflavonoid, flavonoids, and triterpenoid glycosides (saponins) components are highly regarded in the cosmetic industry. This study has been planned as the first project for formulating a new herbal shampoo by utilizing the aqueous extracts of G. glabra . Materials and Methods: The dried powdered root of G. glabra was extracted with boiled water through percolation method, and the pH was set by ammonia; then it was used with other constituents to formulate the herbal shampoo...
October 2018: Journal of Pharmacy & Bioallied Sciences
Nor Faizatul F Ismail, Chin Fen Neoh, Qi Ying Lean, Amir H Abdullah, Siong Meng Lim, Kalavathy Ramasamy, Rahul P Patel, Long Chiau Ming, Yee Chang Soh
Aims: Facial candling is one of the traditional treatments that is claimed to be able to help in curing or reducing various allergy and inflammation conditions such as allergic rhinitis. We aimed to explore the perceptions of participants with allergic rhinitis toward their disease conditions and facial candling treatment. Materials and Methods: The study used a qualitative exploratory design, comprising 12 in-depth interviews. A semi-structured topic guide was used to explore all relevant aspects of the topic, which were audio recorded, transcribed verbatim...
October 2018: Journal of Pharmacy & Bioallied Sciences
Muhammad Tariq Aftab, Atta Abbas Naqvi, Aseel Fuad Al-Karasneh, Syed Azizullah Ghori
Objective: To evaluate the impact of religiosity on subjective life satisfaction and perceived academic stress in undergraduate pharmacy students. Materials and Methods: This 1-month descriptive study focused on pharmacy students of a public-sector university and used three survey questionnaires. The questionnaires included: the Duke University Religion Index to assess religiosity, Subjective Happiness Scale for documenting subjective happiness of life, and Perceived Stress Scale for evaluation of perceived stress due to academic load...
October 2018: Journal of Pharmacy & Bioallied Sciences
Ayon Bhattacharya, Prashant Tiwari, Pratap K Sahu, Sanjay Kumar
Moringa oleifera is a valued medicinal plant in traditional folk medicine. Many pharmacological studies have shown the ability of this plant to exhibit analgesic, anti-inflammatory, antipyretic, anticancer, antioxidant, nootropic, hepatoprotective, gastroprotective, anti-ulcer, cardiovascular, anti-obesity, antiepileptic, antiasthmatic, antidiabetic, anti-urolithiatic, diuretic, local anesthetic, anti-allergic, anthelmintic, wound healing, antimicrobial, immunomodulatory, and antidiarrheal properties. This review is a comprehensive summary of the phytochemical and pharmacological activities as well as the traditional and therapeutic uses of this plant...
October 2018: Journal of Pharmacy & Bioallied Sciences
Mohammad J Siddiqui, Mohammed S M Saleh, Siti N B Binti Basharuddin, Siti H Binti Zamri, Mohd H Bin Mohd Najib, Muhammad Z Bin Che Ibrahim, Nur A Binti Mohd Noor, Hanin N Binti Mazha, Norazian Mohd Hassan, Alfi Khatib
Saffron, Crocus sativus (Iridaceae), is a perennial herb, which earned its popularity as both medicine and spice. It is an inhabitant of different mountainous regions of Asia Minor to Greece, Western Asia, Egypt, and India. The benefits of saffron as an antidepressant are well-documented. Almost 150 volatile and nonvolatile compounds are obtained from the chemical analysis of this plant. Fewer than 50 constituents elucidated and identified so far showed phytochemical characteristics. The major bioactive compounds identified are safranal, crocin, and picrocrocin, which are responsible for its aroma as well as its bitter taste...
October 2018: Journal of Pharmacy & Bioallied Sciences
Mohsen Keshavarz, Mohammad Hadi Karbalaie Niya, Fahimeh Safarnezhad Tameshkel, Amir Sasan Mozaffari Nejad, Seyed Hamidreza Monavari, Hossein Keyvani
Background: Xenotropic murine leukemia virus-related virus (XMRV) is a gamma retrovirus, which has been detected in patients with prostate cancer, chronic fatigue syndrome, and general population with a number of acquired infections such as infection with human T-cell lymphotropic virus (HTLV) and human immunodeficiency virus (HIV). The aim of this study was to determine the HTLV-1 and XMRV coinfection for the first time in Iranian patients who were admitted to the Tehran hospitals. Materials and Methods: Two hundred and ninety one patients suspected with HTLV-1 were referred to the hospitals affiliated to the Iran University of Medical Sciences, Tehran, Iran from April 2012 to October 2016...
July 2018: Journal of Pharmacy & Bioallied Sciences
Hanine Almubayedh, Rizwan Ahmad, Atta A Naqvi, Niyaz Ahmad
Background: Cinnamon ( Cinnamomum zeylanicum ) is a herb that is used traditionally as a flavoring agent as well as for its health benefits in different parts of the world. Its use may vary among cultures. Aim: To observe the knowledge and uses regarding cinnamon in the Saudi population. Materials and Methods: A 2-month cross-sectional study was conducted in Khobar, Saudi Arabia, using a novel questionnaire in Arabic language. Results: A total of 585 responses were collected...
July 2018: Journal of Pharmacy & Bioallied Sciences
Mohd Akhtar Ali, Hamiduddin, Mohammad Zaigham, Mohammad Ikram, Rajeev Ranjan
Introduction: Kushta of Shangarf (KS) is in therapeutic use since long time in Unani and Ayurvedic medicine. It requires extensive assessment with respect to its safety and processing because of the presence of mercury. KS prepared with Shangarf (HgS), Phitkari (alum), and Jozbua ( Myristica fragrans Houtt.) was selected for the study. It is indicated as tonic, increases blood production, and improves complexion of face. Preparation of KS by classical and contemporary method and its comparative physicochemical analysis was attempted in this work...
July 2018: Journal of Pharmacy & Bioallied Sciences
Bashir A Yousef, Amina I Dirar, Mohamed Ahmed A Elbadawi, Mohamed K Awadalla, Magdi A Mohamed
Background: Plants of the Amaryllidaceae family have been under intense scrutiny for the presence of a couple of alkaloidal secondary metabolites with endued cytotoxic activity, such as pancratistatin ( 1 ), 7-deoxypancratistatin ( 2 ), narciclasine ( 3 ), 7-deoxynarciclasine ( 4 ), trans -dihydronarciclasine ( 5 ), and 7-deoxy- trans -dihydronarciclasine ( 6 ). Nevertheless, preclinical evaluation of these alkaloids has been put on hold because of the limited quantity of materials available from isolation...
July 2018: Journal of Pharmacy & Bioallied Sciences
Harshad O Malve
Abuse of substances or methods to enhance the performance is becoming very common in the sports, which often destroys the spirit of competition. The regulatory bodies for sports have reported rates ranging from 5% to 31% for the use of performance-enhancing substances among athletes. Athletes can have serious injuries and morbidities, leading to poor health with the use of such substances. Commonly abused agents in sports include anabolic-androgenic steroids and its analogs, blood, erythropoietin, growth hormone and its derivatives, nutritional supplements, creatine, amphetamines, beta-hydroxy-beta-methylbutyrate (HMB), stimulants, and analgesics...
July 2018: Journal of Pharmacy & Bioallied Sciences
Nallan Csk Chaitanya, Arvind Muthukrishnan, C M S Krishnaprasad, Gali Sanjuprasanna, Poojaragini Pillay, Balmoori Mounika
Pain is an unpleasant subjective feeling having implications on both physical and mental realm. Multiple dimensions of pain involving behavioral, spiritual, emotional, and cognitive changes have been studied and pathways elucidated. It is stressed that the nature in which pain is modulated and perceived at a higher center is a complex phenomenon. One of the main goals of pain modulation is to modify pain to a more tolerable level, rather than its complete eradication. Different pain management interventions were tried but have effects that are more adverse...
July 2018: Journal of Pharmacy & Bioallied Sciences
Kamran Ashraf, Sadia Sultan, Aishah Adam
Orthosiphon stamineus Benth. (Lamiaceae) is a valued medicinal plant in traditional folk medicine. Many pharmacological studies have demonstrated the ability of this plant to exhibit antimicrobial, antioxidant, hepatoprotection, antigenotoxic, antiplasmodial, cytotoxic, cardioactive, antidiabetic, anti-inflammatory activies. This review is a comprehensive summary of the presently available chemical, pharmacological investigations as well as the traditional and therapeutic uses of this plant. Important and different experimental data have been addressed along with a review of all phytochemicals identified in this plant, including flavonoids, terpenoids, and essential oils...
July 2018: Journal of Pharmacy & Bioallied Sciences
Gibson S T Daniel, Manigandan Thiruppathy, Nalini Aswath, Sankar R Narayanan
Oral cancer is the fifth most common cancer in the world, accounting for numerous deaths annually. The 5-year survival rate remains approximately 50% for oral squamous cell carcinoma (OSCC) in the past several decades. Early detection plays a vital role in the survival rate of the patients. There is no accurate, cost-effective, and reliable method for the screening of patients with OSCC. Hence, many patients are diagnosed at advanced stages. Early detection would, therefore, help to identify patients and modify treatment with close monitoring...
April 2018: Journal of Pharmacy & Bioallied Sciences
Pratima Gupta, Ruchi Dua, Mohit Bhatia, Puneet K Gupta, Neelam Kaistha
Strongyloides stercoralis is a soil-transmitted helminth that occurs almost worldwide, yet estimates about its prevalence are not well documented. The spectrum of clinical manifestations of strongyloidiasis is wide, ranging from asymptomatic disease to hyperinfection or dissemination of larvae involving multiple organ systems. Immunosuppression can increase the risk of hyperinfection syndrome in patients with strongyloidiasis. Strongyloidiasis continues to remain a neglected tropical disease, the diagnosis of which is often overlooked by clinicians and diagnosticians alike...
April 2018: Journal of Pharmacy & Bioallied Sciences
Priyanka Gupta, Mohit Bhatia, Pratima Gupta, Balram J Omar
Context: Possible linkage between biocide and antibiotic resistance in bacteria is a major area of concern. Aim: To evaluate the susceptibility of multidrug-resistant (MDR) bacteria to four commonly used biocides. Settings and Design: A pilot study was conducted in a tertiary care hospital from April to November 2017. Materials and Methods: Fifty-four MDR bacterial isolates, namely Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa , and Staphylococcus aureus , were obtained from various clinical samples of inpatients...
April 2018: Journal of Pharmacy & Bioallied Sciences
Sahithi Sharma, Shubhatara Swamy, Anupam Bhambhani, Pratibha Nadig
Introduction: This study was carried out to collect and analyze the adverse drug reactions (ADRs) reported with use of anticoagulants, heparin and fondaparinux. These drugs are vital in the treatment of unstable coronary artery diseases and emergencies. Materials and Methods: A cross-sectional study with active reporting of ADRs from cardiology and medicine department was conducted. The type of reaction was assessed by Rawlins and Thomson criteria, causality by Naranjo probability scale, severity by modified Hartwig criteria, and preventability by Schumock and Thornton criteria...
April 2018: Journal of Pharmacy & Bioallied Sciences
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